Specialty Construction Research Articles

The industry demand oriented construction of intelligence medicine specialty in traditional Chinese medicine university: teachers’ perspective

BackgroundThe aim of this study was to explore the relationships between teaching competence, career development, industrial orientation, and specialty construction in the case of intelligent medicine specialties in universities of traditional Chinese medicine, as well as the influencing factors of specialty construction.MethodsTwo-stage sampling with unequal probability was conducted to distribute self-administered questionnaires in the fieldwork. A structural equation model was built to investigate the influencing factors of specialty construction. Forty-two teachers were recruited and completed the questionnaire.ResultsThe study found that teaching competence, career development, and industrial orientation positively affect specialty construction at a significant level. Career development and industrial orientation play chain mediating roles in the effect of teaching competence on specialty construction.ConclusionsIn the construction of intelligent medicine specialties, a professional curriculum system should be built that caters to industrial demand and is combined with industrial development, the traditional mode of teaching should be transformed, and the transformation of theoretical knowledge into practical ability should be promoted. Innovations in teaching modes should be achieved by introducing information technology, and the teacher evaluation system should be optimized.

Based on Three-Stage Data Envelopment Analysis of The Efficiency Evaluation Model of Specialty Construction

Based on Three-Stage Data Envelopment Analysis of The Efficiency Evaluation Model of Specialty Construction

Study on the Adaptability of Specialty Construction of Chongqing Higher Education Institutions to the Development of "33618" Modern Manufacturing Cluster System

This paper takes the industrial development of 33618 modern manufacturing clusters in Chongqing Municipality as the actual background as the basis. The purpose of this paper is to study the adaptability of the construction of higher education institutions and the development of "33618" modern manufacturing cluster system, analyze the degree of match between the current higher education institutions' professional settings and the development needs of the manufacturing industry, and put forward corresponding optimization proposals. Through this research, we can more deeply understand the development status and future trends of the city's manufacturing industry, to further promote the high-quality development of the manufacturing industry to provide strong support. The study firstly elaborates the development overview of modern manufacturing industry in Chongqing, combines the development of 33618 modern manufacturing cluster system, and constructs the development model of professional construction applicable to the current economic background. Secondly, through questionnaire survey, interviews and policy text analysis, multi-source data including teachers, students, enterprises and relevant government document statements were collected to ensure the comprehensiveness and accuracy of the research results. The study found that: educational institutions with high technology acceptance are more capable of attracting and cultivating students with innovative spirit and practical ability; effective allocation of resources directly affects the quality of teaching and the enhancement of students' ability; the implementation of teaching reforms can significantly enhance the responsiveness of education and the level of market orientation; and the in-depth promotion of the integration of industry and education is conducive to the accumulation of students' practical experience and the enhancement of their employment competition. In summary, the construction of e-commerce in colleges and universities should comply with the general trend of digital transformation, innovative educational concepts and teaching models, and strengthen cooperation with the industry in order to better adapt to and lead the needs of future e-commerce development. The research results of this paper expand the theoretical vision of 33168 modern manufacturing cluster system development research, and provide experience exploration and practical guidance for the construction of modern manufacturing industry in Chongqing and even the whole country, the new requirements for university professional construction and talent training, collaborate with industry information technology, education, science and technology, human resources and other relevant departments to promote the innovation of manufacturing high-quality development of talent training system, and promote the integration of "industry chain, innovation chain, talent chain, capital chain" depth.

Alterations in the gut mycobiome with coronary artery disease severity

BackgroundCoronary artery disease (CAD) is a prevalent cardiovascular condition, and numerous studies have linked gut bacterial imbalance to CAD. However, the relationship of gut fungi, another essential component of the intestinal microbiota, with CAD remains poorly understood. MethodsIn this cross-sectional study, we analyzed fecal samples from 132 participants, split into 31 healthy controls and 101 CAD patients, further categorized into stable CAD (38), unstable angina (41), and acute myocardial infarction (22) groups. We conducted internal transcribed spacer 1 (ITS1) and 16S sequencing to examine gut fungal and bacterial communities. FindingsBased on ITS1 analyses, Ascomycota and Basidiomycota were the dominant fungal phyla in all the groups. The α diversity of gut mycobiome remained unaltered among the control group and CAD subgroups; however, the structure and composition of the mycobiota differed significantly with the progression of CAD. The abundances of 15 taxa gradually changed with the occurrence and progression of the disease and were significantly correlated with major CAD risk factor indicators. The mycobiome changes were closely linked to gut microbiome dysbiosis in patients with CAD. Furthermore, disease classifiers based on gut fungi effectively identified subgroups with different degrees of CAD. Finally, the FUNGuild analysis further categorized these fungi into distinct ecological guilds. InterpretationIn conclusion, the structure and composition of the gut fungal community differed from healthy controls to various subtypes of CAD, revealing key fungi taxa alterations linked to the onset and progression of CAD. Our study highlights the potential role of gut fungi in CAD and may facilitate the development of novel biomarkers and therapeutic targets for CAD. FundingThis work was supported by the grants from the National Natural Science Foundation of China (No. 82170302, 92168117, 82370432), National clinical key specialty construction project- Cardiovascular Surgery, 2024 Reform and Development Program of Beijing Institute of Respiratory Medicine, the Beijing Natural Science Foundation (No. 7222068); the Reform and Development Program of Beijing Institute of Respiratory Medicine (No. Ggyfz202308); and the Clinical Research Incubation Program of Beijing Chaoyang Hospital Affiliated to Capital Medical University (No. CYFH202209).

PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response

Poly(ADP-ribose) polymerase (PARP) inhibitors have emerged as promising chemotherapeutic drugs primarily against BRCA1/2-associated tumours, known as synthetic lethality. However, recent clinical trials reported patients' survival benefits from PARP inhibitor treatments, irrelevant to homologous recombination deficiency. Therefore, revealing the therapeutic mechanism of PARP inhibitors beyond DNA damage repair is urgently needed, which can facilitate precision medicine. A CRISPR-based knock-in technology was used to establish stable BRCA1 mutant cancer cells. The effects of PARP inhibitors on BRCA1 mutant cancer cells were evaluated by biochemical and cell biological experiments. Finally, we validated its invivo effects in xenograft and patient-derived xenograft (PDX) tumour mice. In this study, we uncovered that the majority of clinical BRCA1 mutations in breast cancers were in and near the middle of the gene, rather than in essential regions for DNA damage repair. Representative mutations such as R1085I and E1222Q caused transient extra spindle poles during mitosis in cancer cells. PAR, which is synthesized by PARP2 but not PARP1 at mitotic centrosomes, clustered these transient extra poles, independent of DNA damage response. Common PARP inhibitors could effectively suppress PARP2-synthesized PAR and induce cell senescence by abrogating the correction of mitotic extra-pole error. Our findings uncover an alternative mechanism by which PARP inhibitors efficiently suppress tumours, thereby pointing to a potential new therapeutic strategy for centrosome error-related tumours. Funded by National Natural Science Foundation of China (NSFC) (T2225006, 82272948, 82103106), Beijing Municipal Natural Science Foundation (Key program Z220011), and the National Clinical Key Specialty Construction Program, P. R. China (2023).

Teaching Measures Improvement and Optimization for the Course “Principles and Applications of Optoelectronic Devices”

In the process of promoting the transformation of the social industrial structure, high-level talents are indispensable elements. Therefore, emphasizing the cultivation of high-level talents is necessary and important. Combining with the current social practice for analysis, to cultivate high-level talents, it is necessary to emphasize the construction of high-level specialties. Therefore, at the current stage, the country actively promotes the construction of first-class undergraduate schools and specialties. In the process of constructing first-class undergraduate schools and specialties, curriculum construction and optimization are indispensable contents. Therefore, based on the perspective of first-class undergraduate curriculum construction, the optimization of specific courses and the utilization of teaching reform measures are analyzed, which can provide reference for practice.

Exploration and practice of multi-school co-construction of regional virtual teaching and research room for building electrical and intelligent specialty

To meet the needs of professional development promotion through cross-university collaborative construction in the era of Internet+, a new model of cross-university teaching and research organization is proposed by constructing a regional virtual teaching and research room for remote teaching and research activities among grassroots teaching organizations of different universities, utilizing modern information technology. Led by the national first-class specialty construction site of Building Electrical and Intelligent Specialty at Zhengzhou University of Light Industry, a cross-university regional virtual teaching and research room for this specialty is established in collaboration with other universities offering the same specialty in Henan province. This paper outlines the efficient and stable operation mechanism for the regional virtual teaching and research room’s multi-university collaborative construction and explores the co-construction path for cross-university regional virtual teaching and research rooms. A high-quality resource sharing platform for multi-university collaborative construction is built within the regional virtual teaching and research room, enabling intercollegiate high-quality resource and outstanding teaching team interconnection, co-construction, and sharing. This approach aims to fully leverage the distinctive features and advantages of the Building Electrical and Intelligent Specialty in each university in the region, promote cooperative development and interdisciplinary integration among partnering universities, and improve the quality of talent cultivation. It may also provide valuable reference and guidance for the collaborative construction of virtual teaching and research rooms across a broader range of universities.

Thoughts on the Curriculum Construction of Japanese Majors Specialty Serving the "Belt and Road"

The training mode of Japanese majors must actively adapt to the strategic policy adjustment of national economic structure, closely meet the actual needs of national development and social progress, properly adjust the curriculum system and syllabus, and scientifically and reasonably formulate the development plan of characteristic majors, so as to promote their sustained and healthy development. This paper discusses the optimization and reform of the curriculum system for Japanese majors, actively Introducing Information Technology into Links of Japanese Major Teaching, the enhancement of the platform for improving the international ability and the construction of educational resources, and makes new thoughts on the curriculum for Japanese majors serving the “Belt and Road”. It is expected that this paper can provide useful reference for other colleges and universities.

Exploration and Practice of Course Construction of Electronic Information Specialty under the Background of Integration of Production and Education

Exploration and Practice of Course Construction of Electronic Information Specialty under the Background of Integration of Production and Education

融入商科特色的智能科学与技术新专业建设探讨

融入商科特色的智能科学与技术新专业建设探讨

我国高校机电工程专业建设进展

我国高校机电工程专业建设进展

Practical Research on Promoting The Construction of New Engineering Education through Discipline Competition by PDCA Cycle

<p>At the beginning of the emergence of the concept of new engineering, its connotation interpretation and paradigm change theme have become the focus of attention. The new engineering should not only pay attention to the construction of new industries and new specialties under the new technology, but also pay attention to the continuous training effect of talents under the new engineering education. Discipline competition is an effective way to cultivate the innovation and entrepreneurship ability of college students and improve their comprehensive quality. In order to promote the sustainable and good construction of new engineering education in Colleges and universities, this paper uses PDCA cycle as a means to integrate multi-disciplinary technology through discipline competition, promote the ability of college students to solve complex engineering problems, and thus improve the teaching quality of new engineering. Practice has proved that PDCA is applied to discipline competition in a circular way, providing a feasible path for the implementation of new engineering. After three years of tracking assessment on three different classes of computer science, the graduation design score has been raised from about 82 points to about 85 points, and the students’ theoretical level, practical ability, innovation ability and discipline competition design level have been significantly improved.</p> <p> </p>

Exploration of University Student Talent Cultivation for Innovative Entrepreneurship Based on the "Tutorial System"

Enhancing the innovative entrepreneurial capabilities of contemporary university students and cultivating specialized application-oriented talents is one of the core issues in the field of higher education research in China at this stage. Among them, the practice teaching team based on the "tutorial system", which combines school professional teachers with frontline industry experts, can improve the societal value transformation of classroom theoretical teaching outcomes through industry-led "real-case, real-action" projects. This in turn promotes the industry participation of university faculty and student teams, further optimizing teaching modules and objectives. Taking the cultural creation project published by Shanghai Sanlian Bookstore as a case study, this article elaborates on the advantages of the "tutorial system" talent cultivation model in industry project collaboration, the application transformation of professional course knowledge points, and the realization of guided innovation achievements. This serves as a reference for the reform of university professional teaching and the construction of first-class specialties.

Research on Strategies of Specialty Construction of Environmental Disciplines in the Context of Petroleum and Petrochemical Characteristics

In the context of the new era, with the focus on talent training, "government, industry, academia and research" integration, environmental disciplines construction deficiencies are increasingly apparent, in view of its problems, in the context of petroleum and petrochemical characteristics of the construction of the whole process of the linkage mechanism, a full range of evaluation system. This article not only provides comprehensive guidance for the construction of the environmental discipline in our school, but also provides effective mechanism and method guarantees for the deep integration of the demand side of senior environmental protection professionals and the supply side of universities exporting talents to the chemical industry. It has important practical and far-reaching strategic significance for the construction and development of the environmental discipline in our school.

The enlightenment of western university construction to college education construction in China

There are many factors involved in improving the quality of university education.The most important factor restricting. the quality of university education is specialty construction.The university's specialty is the part that is most closely related to the labor market.Strengthening specialty construction,especially the construction of characteristic specialties is undoubtedly an important measure. A stone from another mountain can conquer a jade.The history and present situation of characteristic subject development and specialty construction in western universities enlighten us a lot.Under the realistic background of our country, the government and universities should learn from the concept of specialty management in western countries, and make joint efforts to strengthen the construction of characteristic specialty.

Uptake of the core outcome set on polycystic ovary syndrome before and after its publication.

Does the core outcome set (COS) on polycystic ovary syndrome (PCOS) impact the selection of research outcomes? Following the publication of the COS on PCOS, an increasing number of trials are reporting both the generic domain and body mass index; however, the uptake of this COS has not been as extensive as expected. The COS on PCOS included 33 core outcomes in the following seven domains: the generic (3), metabolic (8), reproductive (7), pregnancy (10), psychological (3), oncological (1), and long-term (1). This was done to improve consistency in outcome selection and definition. However, thus far, no studies have investigated the effectiveness of this COS in the above-mentioned tasks. A methodological study based on the trial registries, including 395 eligible clinical trials registered between 1 January 2018 and 21 September 2022. A total of 1258 registered clinical studies on PCOS were retrieved from the World Health Organization International Clinical Trials Registry Platform. Of those, 395 were selected according to the inclusion and exclusion criteria, and divided into two groups based on the publication date of the COS on PCOS (4 February 2020): pre-publication and post-publication. The practical uptake of this COS was explored after data collation, assessment, comparison of the uptake of core outcomes or domains before and after the publication of this COS, and correlation analysis between the domains. There were 26 out of 33 core outcomes and five out of seven domains reported in the 395 trials. The highest uptake was observed for the reproductive domain and the reproductive hormonal profile (63.0% and 38.7%, respectively). After the publication of the COS on PCOS, the uptake of the generic domain and body mass index increased from 24.1% to 35.8% (P = 0.011) and 17.8% to 26.5% (P = 0.039), respectively. The total number of reported core outcomes in the generic domain met statistical significance (P = 0.012). Moreover, multivariable analyses still supported the above finding in the generic domain. Correlation analysis showed that most of the domains were positively correlated with each other. However, the pregnancy domain was negatively correlated with the metabolic domain. Reasons responsible for the unsatisfactory uptake may be the absence of specific definitions of core outcomes, as well as the lack of awareness among researchers regarding this COS. Due to the lack of standardized definition of outcomes, it was difficult to avoid some subjectivity in the process of consistency assessment. Two years after its publication, there was no substantial improvement in the uptake of the COS on PCOS. This suggests that this COS may require further revision, refinement, and promotion to improve the comparability of PCOS studies. This work was funded by Beijing Municipal Health Science and Technology Achievements and Appropriate Technology Promotion Project (BHTPP2022069), and the special fund of Beijing Key Clinical Specialty Construction Project.The authors do not have conflicts of interest to declare. N/A.

Retracted: Research on Application Adaptability of Big Data and IoT in Discipline Construction of Mechanical Engineering Specialty in Universities

Retracted: Research on Application Adaptability of Big Data and IoT in Discipline Construction of Mechanical Engineering Specialty in Universities

Best Practices for Reasonableness of Compensation Analysis in Taxation Disputes

The U.S. Tax Court case Clary Hood, Inc v. Commissioner involves a closely held C corporation’s dispute regarding the reasonableness of executive/shareholder compensation tax deductions. There was no dispute in this litigation that CHI was an extremely successful specialty construction company during the tax years at issue. And, there was no dispute in this litigation that Clary Hood, the company CEO and (with his wife) shareholder, was largely responsible for the construction company’s success during the tax years at issue. The disputed issue in the litigation was whether the bonuses paid to Hood in 2015 and 2016 exceed a reasonable amount of executive compensation for the services Hood actually performed for the company. In its memorandum decision, the Tax Court provided a fulsome discussion of the methodology and analysis it applied in addressing this reasonableness of executive/shareholder compensation issue. This judicial discussion provides meaningful practical guidance.

Research on Innovation Practice Platform Construction and practice path of automotive Specialty

This paper first analyzes the necessity and significance of the construction of the innovation practice platform for automobile majors, and analyzes five models of the innovation practice platform and their respective application scope according to the level of technology maturity. On this basis, it proposes that the operation of the innovation practice platform needs to strengthen the construction of mechanism, operation, talent and achievement. Then it puts forward that the innovation practice platform needs to achieve the expected results, and finally puts forward the existing problems and adopted countermeasures and suggestions.

Research on Improving Engineering Construction of International Trade Talent Cultivation with Industry Education Integration

With the requirements from development, it is proposed to "accelerate the construction of first-class universities and first-class disciplines, and realize the connotative development of higher education", and the National Conference on Education requires colleges and universities to "focus on the cultivation of innovative, composite and application-oriented talents". Applied undergraduate colleges and universities in international trade need to promote the construction of disciplines and specialties, deepen the reform of education and teaching mode, and cultivate innovative and applied talents in line with the market and the needs of the times through the collaborative education of industry, academia and research.