The vehicle transmission system is a power transmission device between the engine and the wheel load. As the connecting hub of the power system, the travel system and the braking system, it ensures the mobility and safety of special equipment in combat missions. From the four aspects of the transmission system structure composition characteristics, power transmission characteristics, energy flow characteristics and vehicle power characteristics, it is demonstrated that the transmission efficiency is an important technical indicator for evaluating the performance of the transmission system; based on the analysis of the relationship between power loss and transmission efficiency, a global model framework of the power loss of the transmission system is established from the perspective of the generation mechanism and structural characteristics, providing a theoretical basis for the performance characterization of the transmission system; from the three aspects of theoretical numerical research, simulation research and experimental demonstration research of transmission efficiency, the difficulties and key points of the research on the power loss of the vehicle transmission system are discussed, and it is pointed out that the multi-media and multi-parameter coupling simulation analysis and experimental research of large-scale mechanical equipment under complex operating conditions can provide guidance for the performance optimization and health management of vehicle transmission components, and the performance evaluation and matching design of the transmission system; it is expected that the comprehensive transmission efficiency analysis under multiple factors, as well as the coupling research of power loss characteristics, efficiency characteristics and performance degradation characteristics based on intelligent algorithms have practical engineering significance for the performance monitoring and evaluation of large-scale mechanical equipment.