BACKGROUND Psychological function after transplantation has garnered increased attention, and the relationship between recipients and corresponding donors has been investigated in medical research. Here, we investigated potential qualitative and quantitative psychological and lifestyle changes among recipients after heart transplantation and their correlation with donors. MATERIAL AND METHODS Transplant recipients, their families, and the donor's families were interviewed. The interview was semi-structured, featuring open-ended questions related to 5 domains: preference, emotions and temperament, memory, self-identity, and social identity. Qualitative data were analyzed by triangulation and deductive content analysis. Quantitative data were collected using the Big Five Inventory-19 (BFI-19) questionnaire, to complement the domain of emotions and temperament. RESULTS Overall, 20 recipients, 15 recipients' families, and 13 corresponding donors' families were interviewed (5 recipients' families and 7 donors' families refused to participate) between October 2020 and July 2021. The data were matched to 13 groups, each including at least 1 recipient and the corresponding donor. Finally, 13 recipients, 9 corresponding recipients' families, and 13 corresponding donors' families were identified. Similarities between recipients' psychological and lifestyle changes and the corresponding donors' traits were primarily identified in the aspects of diet, emotions and temperament, and special experiences other than dreams. The BFI-19 data showed no significant correlations between recipients and the corresponding donors' families. CONCLUSIONS Our findings indicate significant psychological and lifestyle changes in recipients before and after heart transplantation, with 38% exhibiting characteristics partly similar to those of their donors. Further investigation is needed to explore the psychobiological correlation between recipients and donors.
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