Spearman Rank Correlation Test Research Articles

THE THE ROLE OF NUTRITIONAL STATUS ON HEMOGLOBIN LEVELS IN ADOLESCENTS

Background: Adolescents were one of the strong foundations for the future of the nation because of their role in development and progress of the country. Healthy physical and psychological conditions will form a strong and resilient adolescent character which is affected by adequate nutritional intake. So that if nutrients are not sufficient, it can cause disturbances in metabolic processes. Inadequate intake of nutrients such as protein and iron will aggravate the occurrence of anemia and lead to malnutrition. Indirectly, nutritional status will also affect the occurrence of anemia. Objectives: This study was to examine the relationship between nutritional status and adolescent hemoglobin levels. Methods: This study was an analytic study with Cross Sectional approach. Respondents were 46 students of SMP PGRI 01 Bantur in Malang regency conducted in August 2023. Independent variable was nutritional status using weight, height and Body mass index (BMI) and dependent variable was anemia using hemoglobin level. BMI was calculated using formula weight divided by height square. The analysis used both univariate and bivariate analysis. Bivariate analyzed using Spearman rank correlation test. Results: Results showed 76,1% adolescents classified normal nutritional, 19,6% overweight and 2,2% underweight and obese. The hemoglobin level, 86,9% normal and 13,1% anemia. Based on the results of statistical tests using rank spearman test, the p value = 0.044 less than 0,05. It means there was a significant correlation between nutritional status and anemia. Conclusion: There is a relationship between nutritional status with Hb levels in adolescents. Enrichment of nutritional intake will give big impact on nutritional and anemia status among adolescents.

Morphological Changes and Inflammation Preceded the Pathogenesis of 1,2-Dimethylhydrazine-Induced Colorectal Cancer.

This study examined the morphological changes in the colonic mucosa and the presence of inflammation in rats induced with 1,2-dimethylhydrazine (DMH) 30 mg/kg BW over 9, 11, and 13 weeks without a latency period. Hematoxylin and eosin staining was performed to assess the morphology and characteristic alteration of the epitheliocytes in the colon. Immunohistochemistry was employed to assess the expression of tumor necrosis factor (TNF)-α and cyclooxygenase-2 (COX-2). The difference in the severity of inflammation and COX-2 expression was examined using one-way analysis of variance. The correlation of COX-2 expression with the severity of inflammation was analyzed using Spearman's rank correlation test. Until week 13, chronic inflammation and non-hyperplastic and hyperplastic aberrant crypt foci occurred. The severity of inflammation gradually shifted from high moderate to low moderate. TNF-α expression was high in all groups; however, COX-2 expression was gradually lower with longer duration of induction, which corresponded with the severity of inflammation. DMH induction until week 13 without a latency period caused chronic inflammation without the formation of adenoma or adenocarcinoma. A very strong correlation was established between COX-2 expression and inflammation.

Korelasi Efikasi Diri dengan Tingkat Intradialitic Weight Gain (IDWG) Pada Pasien Gagal Ginjal Kronik

Background: Kidney failure in carrying out its functions at the terminal stage requires treatment in the form of hemodialysis. In hemodialysis patients, adhering to fluid intake restrictions has a very vital role to prevent further complications. The success of fluid and diet management in therapy is measured by the level of Interdialytic Weight Gain (IDWG). One of the things that affects IDWG during the hemodialysis therapy period is self-efficacy. Purpose: To determine the relationship of self-efficacy with the level of Interdialytic Weight Gain (IDWG) of chronic kidney disease patients in the hemodialysis unit of RAA Soewondo Pati Hospital. Methods: This study is a correlational analytical study, with a cross-sectional research design, a sampling method using consecutive sampling, with a total sample of 68 respondents and data collection using questionnaires. Results: The results of this study found that respondents with high category self-efficacy and IDWG levels in the mild category were 38 respondents (50.5%), the results of the analysis with the spearman rank correlation test obtained p value = 0.000< α (0.05) which can be concluded to be a relationship between self- efficacy and the interdialytic weight gain (IDWG) level of chronic kidney disease patients in the hemodialysis unit of RAA Soewondo Pati Hospital. Conclusion: There was a significant relationship between self-efficacy and interdialytic weight gain (IDWG) levels of chronic kidney disease patients in the hemodialysis unit of RAA Soewondo Pati Hospital.

Comparison of the vitality test with sensitivity tests in mature and immature teeth: clinical trial.

One of the most important steps in deciding on the treatment of a tooth is to determine the vitality and health status of the pulp. Since immature teeth innervation is not completed, the response to sensitivity tests may not yield definite results. Pulse oximetry (PO) which is considered as a vitality test, measures the arterial oxygen saturation (SpO2). This study aims to compare PO, electric pulp test (EPT) and cold test in mature and immature permanent teeth. 20 immature and 20 mature permanent incisors of 6-12-year-old ASA1 children who did not use any analgesics, were included in the study. Pulp vitality of the teeth was determined by EPT, cold test and PO. An infant probe of PO device (CMS60D, Contec Medical Systems Co. Ltd, China) was used to determine the SpO2 of the teeth. The SpO2 level is controlled on the patient's finger by a children's probe and an infant probe of PO. Shapiro-Wilk, Spearman rank correlation test and Kruskal-Wallis test/Dunn post-hoc analysis were used for statistical comparisons. There was no significant correlation between finger SpO2 and the mature/immature teeth SpO2 (r=-0.026, r = 0.253). Arterial oxygen saturation values in the immature teeth were significantly higher than in the mature teeth (p = 0.002). There was a high correlation between the vitality response of the EPT, cold test and PO. Pulse oximetry can be used as an effective vitality test compared to sensitivity tests in both immature and mature permanent incisors.

Relationship between Femoral Proximal Bone Quality Assessment by MRI IDEAL-IQ Sequence and Body Mass Index in Elderly Men.

Bone assessment using the MRI DEAL-IQ sequence may have the potential to serve as a substitute for evaluating bone strength by quantifying the bone marrow hematopoietic region (R2*) and marrow adiposity (proton density fat fraction: PDFF). Higher body mass index (BMI) is associated with increased bone mineral density (BMD) in the proximal femur; however, the relationship between BMI and R2* or PDFF remains unclear. Herein, we investigated the correlation between BMI and MRI IDEAL-IQ based R2* or PDFF of the proximal femur. A retrospective single-cohort study was conducted on 217 patients diagnosed with non-metastatic prostate cancer between September 2019 and December 2022 who underwent MRI. The correlation between BMI and R2* or PDFF of the proximal femur was analyzed using Spearman's rank correlation test. Among 217 patients (median age, 74 years; median BMI, 23.8 kg/m2), there was a significant positive correlation between BMI and R2* at the right and left proximal femur (r = 0.2686, p < 0.0001; r = 0.2755, p < 0.0001, respectively). Furthermore, BMI and PDFF showed a significant negative correlation (r = -0.239, p = 0.0004; r = -0.2212, p = 0.001, respectively). In elderly men, the increased loading on the proximal femur due to elevated BMI was observed to promote a decrease in bone marrow adiposity in the proximal femur, causing a tendency for a transition from fatty marrow to red marrow with hematopoietic activity. These results indicate that the MRI IDEAL-IQ sequence may be valuable for assessing bone quality deterioration in the proximal femur.

Application of family nursing documentation in Tarakan City, Indonesia

Documentation of nursing care is authentic proof of nursing service activities, serving as the basis for fulfilling nurses' responsibilities and accountabilities. Family nursing documentation holds distinct characteristics compared to other nursing practice settings. The Indonesian nursing professional organization has established three standards for nursing care: diagnosis, intervention, and outcome. This research aimed to understand how the implementation of family nursing care documentation is conducted by community nurses in Tarakan City. The research was a correlational study with a cross-sectional approach. The study population consisted of all the nurses working in Community Health Centers in Tarakan City, totaling 80 individuals. The sample was selected using total sampling. The research variables included demographic factors, nurses' knowledge about the documentation concept, and the application of family nursing documentation; these were measured using a modified researcher-made questionnaire and declared valid and reliable. The analysis of research data used descriptive analysis and the Spearman Rank correlation test. This research identified that the majority of community nurses in Tarakan City did not implement family nursing documentation, and the level of knowledge regarding nursing documentation concepts was low. The Spearman's rank correlation test yielded a p-value of 0.874, indicating no significant correlation between the level of knowledge and the implementation of family nursing documentation. The inhibiting factors for the implementation of family nursing care documentation primarily included a high workload, a limited number of health center nurses, motivation, and the lack of clear and uniform documentation guidelines.

Eco-Gender Gap Dalam Pemeliharaan Lingkungan di Desa Wisata (Kasus : Rumah Tangga Anggota Komunitas Pecinta Lingkungan di Desa Wisata Batulayang, Kecamatan Cisarua, Kabupaten Bogor)

Batulayang Tourism Village is one of West Java Province's sustainable tourism villages. Gender equality in environmental preservation are an important factor in efforts to preserve the ecological environment. Men and women share equal responsibility for environmental preservation. The purpose of this study is to examine the relationship between environmental preservation and the level of the gender gap. This study uses a mixed method exploratory sequential design approach, applying in-depth interviews for qualitative followed by questionnaires for quantitative data collection. The respondents in this research are 30 household members of the environmental community and 5 people research subjects who were in Ecovillage Program. The Spearman Rank Correlation and Chi-Square Test were utilised in this data processing for quantitative data. The research findings indicate that the Ecovillage Programe has sufficiently increased community participation to care more about the surrounding environment; however, in its implementation in the household sphere, the lack of gender-based environmental awareness causes there to still be a gap between husbands and wives in environmental management because environmental management is often associated with women's domestic role.

Analysis of Dominant Risk Factors for Stroke Incidence and Unhealthy Lifestyle at Sidomulyo Pekanbaru Health Center

The introduction of health in the community is not only seen in the health sector but also must be seen in all sectors that influence health problems. Generally, there are two kinds of causes of stroke. The first is a blockage of the arteries, called ischemic stroke, while the second cause is rupture of blood vessels, or stroke ischemic, while the second cause is a rupture of blood vessels called a hemorrhagic stroke. Other causes of stroke can be a temporary disruption of blood flow to the brain, commonly referred to as an ischemic attack (TIA). These three conditions have a series of potential factors that trigger stroke. Hemorrhagic. Other causes of stroke can be a temporary disruption of blood flow to the brain, commonly referred to as an ischemic attack (TIA). These three conditions have a series of potential factors that trigger stroke. The study employed the Spearman rank correlation test method to investigate the relationship between smoking habits, alcohol consumption, lack of physical activity, and the occurrence of stroke. It involved 41 respondents from the Sidomulyo Health Center's jurisdiction. The findings revealed a significant association between smoking habits and stroke, as indicated by a significance value of 0.007, which is less than the threshold of 0.05. Similarly, there was a significant relationship observed between alcohol consumption and stroke, with a significance value of 0.016. However, the analysis showed no significant correlation between lack of physical activity and stroke, as the significance value of 0.446 exceeded the threshold of 0.05.

A BWM-TOPSIS Linear Programming Model for Evaluating the Performance of Health-Promoting Hospitals with McKinsey 7s Framework in Organizational Management

This research addresses the critical aspect of evaluating operational performance in health promotion hospitals, which play a vital role in providing medical services to local communities. The research proposes an integrated method for performance assessment, utilizing the Best-Worst Method (BWM) and the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) linear programming model. Taking the case of health promotion hospitals in Maha Sarakham province, Thailand, and considering the McKinsey 7s framework's seven criteria, BWM is employed to determine the criteria weights. Subsequently, the TOPSIS linear programming model selects the ideal health promotion hospital based on these weights. The BWM analysis reveals criteria weights in the following order: system, staff, skill, style, structure, strategy, and shared value. The TOPSIS linear programming model identifies SH12 as the top-performing health promotion hospital with a closeness coefficient value of 0.8821. Additionally, a Spearman's rank correlation test validates this proposed method against the original TOPSIS approach, yielding a correlation value of 1.0. These findings provide valuable guidance for organizations, particularly in shaping strategic policies and resource allocation within medical service units, medical equipment, and personnel management in organizational settings. This study offers that the proposed method is simpler and will aid in the ongoing analysis of strengths and weaknesses in the improvement of organizations and development, helping organizations adapt to changes.

Performance of a cost-effective olfactory test to evaluate hyposmia in Parkinson's disease patients.

Parkinson's disease (PD) causes motor and non-motor symptoms such as hyposmia, which is evaluated through olfactory tests in the clinical practice. To assess the feasibility of using the modified Connecticut Chemosensory Clinical Research Center (mCCCRC) olfactory test and to compare its performance with the Sniffin' Sticks-12 (SS-12, Burghart Messtechnik GmbH, Wedel, Germany) test. A transversal case-control study in which the patients were divided into the PD group (PDG) and the control group (CG). The cost and difficulty in handling substances to produce the mCCCRC test kits were evaluated. Sociodemographic characteristics, smoking habits, past coronavirus disease 2019 (COVID-19) infections, self-perception of odor sense, and cognition through the Montreal Cognitive Assessment (MoCA) were also evaluated. The PDG was scored by part III of the Unified Parkinson's Disease Rating Scale (UPDRS-III) and the Hoehn and Yahr Scale (H&Y) scale. Correlations were assessed through the Spearman rank correlation coefficient test (ρ, or rho). The mCCCRC test was easily manufactured and handled at a cost ten times lower compared with the SS-12. The groups (PDG: n = 34; CG: n = 38) were similar in terms of age, sex, level of schooling, smoking habits, and history of COVID-19. The tests results showed moderate correlation (rho = 0.65; p < 0.0001). The CG presented better cognitive performance and scored better in both tests (p < 0.0001). There was a tendency for a negative correlation with age, but good correlation with the MoCA (p = 0.0029). The results of the PDG group showed no correlation with olfactory results and motor performance or disease duration. The self-perception of hyposmia was low in both groups. The mCCCRC is an easy-to-apply and inexpensive method that demonstrated a similar performance to that of the SS-12 in evaluating olfaction in PD patients and healthy controls.

Kepuasan Penggunaan Telemedicine terhadap Keputusan Penggunaan Telemedicine di RSU X Kabupaten Malang

Patients feel dissatisfied when using telemedicine because they feel that the telemedicine service has too many menus, is not clear and is not easy to use. The research design used in this research is a cross-sectional method and is a quantitative study. This research was conducted on patients at the Outpatient Installation of Hospital The sample obtained for this research was 209 people. The data collection technique uses a questionnaire method with a Linkert measurement scale. Data analysis in this study used the Spearman Rank correlation test. The results of the Spearman Rank analysis statistical test in this study to determine the relationship between satisfaction with using telemedicine services and the decision to use telemedicine services at RSU X Malang Regency showed a coefficient value of 0.827. Based on the results of hypothesis testing in this study, it can be concluded that there is a relationship between patient satisfaction (X) and reuse of telemedicine services (Y). Improving the quality of telemedicine, ease of communication and comfort need to be considered, in order to provide patient satisfaction in using telemedicine services and will have an impact on the reuse of these services.

The Effectiveness of Discharge Planning Implementation on the Quality of Life of Post Opname Patients with Heart Failure at Hospital

Background: Heart failure is a disease with a high rehospitalization rate due to patients not fulfilling recommended therapy, for example, breaking a diet, doing excessive physical activity and lack of understanding during discharge planning. This causes a decrease in the quality of life after patient is discharged. Purpose: This research aims to determine the effectiveness of discharge planning implemention on the quality of life of post-opname patients with heart failure at Bhayangkara Hospital, Kediri City. Method: The type of research used is quantitative research with a descriptive cross-sectional study design. The number of samples in this study were 31 respondents with accidental sampling technique. Results: The results of the non-parametric Spearman rank correlation test analysis obtained a value of p = 0.022 (p &lt;0.05) and a correlation coefficient of 0.411 which is moderate and has a positive direction. This shows that there is a positive relationship between the effectiveness of implementing Discharge Planning on the quality of life of post-hospitalized patients with heart failure at Bhayangkara Hospital, Kediri City. Conclusion: Discharge Planning given to patients with heart failure at Bhayangkara Hospital, Kediri City is not yet effective and needs to be improved. However, the majority of respondents have a good quality of life where respondents experience an increase in socialization, psychology, but still experience physical discomfort.

Differences in Glutamate Dehydrogenase (GLDH) and Other Liver Biochemistry Levels before and after Remdesivir Treatment in COVID-19

Background: Remdesivir (RDV) is a broad-spectrum antiviral approved by the Food and Drug Administration (FDA) for the treatment of Covid-19 patients, known to have the potential to cause toxic effects on the liver. Routine monitoring of liver biochemical parameters such as AST, ALT, bilirubin, ALP and GGT, can help detect liver injury. Drug-induced liver injury, according to Hy's law, is characterized by an increase in ALT &gt; 5x ULN, or ALP &gt; 2x ULN, or an increase in ALT &gt; 3x and total bilirubin &gt; 2x ULN, simultaneously. Glutamate dehydrogenase (GLDH) is a sensitive and specific hepatic marker, which can detect liver injury and loss of mitochondrial integrity earlier than other liver biochemical parameters. This study aimed to analyze GLDH levels and liver biochemical parameters before and after RDV therapy in patients with Covid-19. We also analyze several factors that affect liver function and suggest renal function. Methods: This study used an observational analytical with a prospective cohort design, in a population of Covid-19 patients receiving RDV therapy at the infectious emergency department and isolation ward Dr. Soetomo Surabaya for September-November. Consecutive sampling was taken. The subject had drawn blood twice; once before therapy and 5 days after receiving intravenous RDV. GLDH examination is using sandwich ELISA method, while ALT, AST, ALP, GGT, direct and total bilirubin were determined spectrophotometrically. Mann-whitney, the Wilcoxon rank test and Spearman correlation test were used to analyze the data. Results: The number of samples was 34 participants with an average age of 52.47+15.21 years. Concomitant medications were dominated by n-acetylcysteine (94.1%), antioxidants (91.2%) and immunomodulators (82.4%). None of the subjects suffered liver injury induced by RDV according to Hy’s Law. Median GLDH serum levels before RDV treatment 1,14 U/L and after 5 days RDV administration 0,85 U/L (p=0,945), AST (36,4 U/L; 34, 00U/L; p=0,140), ALT (30,43 U/L; 30,20 U/L; p=0,301), DBI (0,15mg/dL; 0,24mg/dL; p=0,090), TBI (0,49mg/dL; 0,50mg/dL; p=0,567), ALP (85,0U/L; 87, 5 U/L; p=0,313) dan GGT (64,5U/L; 71,0U/L; p=0,871). The use of concomitant medication was thought to have protective properties against hepatocytes. Conclusion: After 5 days of RDV treatment, there is no evidence of liver injury. There are no significant differences in GLDH levels and other liver biomarker parameters compared to baseline. There is no difference in delta GLDH levels between groups with and without renal impairment.

Relationships between self-efficacy, health belief, and self-care among type 2 diabetes mellitus

Introduction: Diabetes mellitus (DM) patients need to be empowered to manage their conditions. Some factors that affected the empowerment of diabetes mellitus patients were self-efficacy, health beliefs, and self-care. Self-efficacy positively correlates with health belief and self-care among patients with type 2 DM. However, such evidence is still limited in the Health Care Centers, especially in Yogyakarta. This research aimed to identify self-efficacy and the relationship between health belief and self-care among Type 2 DM patients. Methods: This is a correlative analytical of quantitative research using the cross-sectional approach. Purposive sampling was used to collect the samples, which were 83 patients who belonged to the inclusion criteria. This research was conducted in the Primary Health Center in Bantul Yogyakarta between April and May. The statistical tests used the Spearman rank correlation test due to the abnormal distribution. Results: The mean of self-efficacy, health belief, and self-care were 84.9±9.3; 105,1±7,2; 67,8±7,7, respectively. There was a significant relationship between self-efficacy and health belief at the value of p&lt;0.000, and there was a relationship between self-efficacy and self-care at the value of p&lt;0.000. Conclusion: Positive correlations were achieved between self-efficacy and health belief and between self-efficacy and self-care in diabetes mellitus patients.

The Relationship of Physical Activity, Energy, and Protein Intake with Nutritional Status in Adolescents at Junior High School

Indonesia is still in a nutritional emergency. Undernutrition or overnutrition is a health problem that is often found in adolescence. Nutritional problems that occur are influenced by an imbalance between physical activity and macronutrient intake in adolescents. This study aims to determine the relationship between physical activity, energy intake, and protein intake with nutritional status in adolescent girls. Observational study with a cross-sectional approach conducted in July – August 2023 at Junior High School 2 Long Bagun, Mahakam Ulu Regency, East Kalimantan. A total of 42 adolescents were included as samples based on purposive sampling by setting inclusion and exclusion criteria. Physical activity variables were measured in the International Physical Activity Questioner (IPAQ) while energy and protein intake were obtained through a 24-hour food recall form. The BMI / U formula measures nutritional status-data analysis using the Spearman Rank correlation test. Our findings show the majority of adolescents with moderate physical activity (76.2%), adequate energy intake (66.7%), and adequate protein intake (66.6%). The results of the relationship analysis showed physical activity (p = 0.001, r = 0.512), energy intake (p = 0.001, r = 0.503), protein intake (p = 0.002, r = 0.459) with the nutritional status of adolescents at Junior High School 2 Long Bagun. There is a significant relationship between physical activity, energy intake, and protein intake with the nutritional status of adolescents at Junior High School 2 Long Bagun. These findings are empirical evidence for the formation of better adolescent health programs

Impact of environmental factors on Biomphalaria pfeifferi vector capacity leading to human infection by Schistosoma mansoni in two regions of western Côte d'Ivoire

AbstractBackgroundIntestinal schistosomiasis remains a worrying health problem, particularly in western Côte d'Ivoire, despite control efforts. It is therefore necessary to understand all the factors involved in the development of the disease, including biotic and abiotic factors. The aim of this study was to examine the factors that could support the maintenance of the intermediate host and its vectorial capacity in western Côte d'Ivoire.MethodsData on river physicochemical, microbiological, and climatic parameters, the presence or absence of snails with Schistosoma mansoni, and human infections were collected between January 2020 and February 2021. Spearman rank correlation tests, Mann–Whitney, analysis of variance (ANOVA), and an appropriate model selection procedure were used to analyze the data.ResultsThe overall prevalence of infected snails was 56.05%, with infection reaching 100% in some collection sites and localities. Of 26 sites examined, 25 contained thermophilic coliforms and 22 contained Escherichia coli. Biomphalaria pfeifferi was observed in environments with lower land surface temperature (LST) and higher relative air humidity (RAH), and B. pfeifferi infection predominated in more acidic environments. Thermal coliforms and E. coli preferred higher pH levels. Lower maximum LST (LST_Max) and higher RAH and minimum LST (LST_Min) were favorable to E. coli, and lower LST_Max favored coliforms. The presence of B. pfeifferi was positively influenced by water temperature (T °C), LST_Min, RAH, and precipitation (Pp) (P < 0.05) and negatively influenced by pH, total dissolved solids (TDS), electrical conductivity (EC), LST_Max, and mean land surface temperature (LST). The parameters pH, TDS, EC, LST_Min, LST, and Pp had a positive impact on snail infection, while LST_Max had a negative impact on infection. Only pH had a positive effect on coliform and E. coli abundance. Of the 701 people examined for human schistosomiasis, 73.13% were positive for the point-of-care circulating cathodic antigen (POC-CCA) test and 12.01% for the Kato–Katz (KK) test. A positive correlation was established between human infections and the abundance of Biomphalaria (r2 = 0.879, P = 0.04959).ConclusionsThe results obtained reflect the environmental conditions that are conducive to the maintenance of S. mansoni infection in this part of the country. To combat this infection as effectively as possible, it will be necessary not only to redouble efforts but also to prioritize control according to the level of endemicity at the village level.Graphical

The Relationship between Long Time Undergoing Hemodialysis and Stress Levels in Chronic Kidney Failure Patients Undergoing Hemodialysis at Bendan Regional Hospital, Pekalongan City

Chronic renal failure is characterised by irreversible decline in kidney function. Chronic renal failure requires haemodialysis therapy. Long time undergoing haemodialysis can cause psychological problems such as stress. The purpose of this study was to assess the relationship between length of haemodialysis and stress level in chronic renal failure patients undergoing haemodialysis at Bendan Hospital, Pekalongan City. Methods: The research design used descriptive correlative with cross sectional approach. The study population were all chronic renal failure patients undergoing haemodialysis at Bendan Hospital, Pekalongan City, as many as 70 people. The study sample were 70 patients with chronic renal failure who underwent haemodialysis at Bendan Hospital, Pekalongan City by total sampling. The research instruments were questionnaires and Perceived Stress Scale (PSS). Data analysis used spearman rank correlation test. Results: the majority of respondents, 36 people (51,4%) had undergone haemodialysis for ≤ 1 year and the majority of respondents, 58 people (82.9%) experienced moderate stress. The results showed that there was relationship between the length of undergoing haemodialysis with stress levels in chronic renal failure patients undergoing haemodialysis at Bendan Hospital, Pekalongan City with a ρ value: 0,000 with a correlation value of rho of -0,438, which means that the length of haemodialysis has a moderate strength of relationship with stress levels. Conclusion: length of haemodialysis is associated with stress levels of chronic kidney failure patients

Do Patients With Mental Illness Undergoing Office-Based Sedation Require an Increased Propofol Dosage?

Providers report needing higher sedative doses to achieve adequate sedation in patients with mental illnesses. These claims, however, have not been thoroughly assessed. The purpose of the study was to measure the association between mental illness and the propofol dosage necessary to achieve a satisfactory level of anesthesia. The study consisted of a single-center, retrospective cohort consisting of patients treated by oral and maxillofacial surgery at the University of Cincinnati Medical Center in 2020. The study was comprised of subjects 15 or older who were American Society of Anesthesiologists (ASA) classification I or II. Subjects under 15 or ASA III or higher were excluded from the study. The predictor variable was the presence or absence of mental illness. The primary outcome was the total dose of propofol, measured as the total amount of propofol administered divided by the patient's weight in kilograms divided by the length of the procedure in minutes (mg/kg/min). The secondary outcome was the Richmond Agitation-Sedation Scale (RASS) score achieved during sedation. Sex, race, ethnicity, age, weight, body mass index, ASA score, prior tobacco use, marijuana use, use of adjunct midazolam, fentanyl, and ketamine during the procedure, and type of procedure served as covariates. Test statistics were calculated using the Wilcoxon rank-sum test, Kruskal-Wallis test, Spearman rank correlation test, and χ2 test for bivariate analyses. Linear and logistic regression models were used to estimate association while controlling for confounding. P values ≤ .05 were considered statistically significant. The study sample was 409 subjects (36.92% male, mean age 28.27±12.20years). In bivariate analysis, mental illness did not show any association with propofol dose (mean dose with mental illness 150.85±143.97mg/kg/min, mean dose without mental illness 116.54±104.16, P=.08) or RASS score (sufficiently sedated with mental illness 63.38%, sufficiently sedated without mental illness 58.80%, P=.36). After adjusting for all previously mentioned covariates, mental illness was statistically associated with propofol dose (P<.01). Adjusting for covariates, only sex had a statistically significant association with the RASS score (P<.05). The findings suggest that a patient's mental illness may influence the amount of sedative required to achieve satisfactory anesthesia.

Buprenorphine prescribing and treatment accessibility in response to regulation changes due to the COVID-19 public health emergency

BackgroundIn 2021, over 80,000 fatal overdoses occurred in the United States. Since 2020, the federal government has enacted multiple regulatory changes around buprenorphine prescribing for opioid use disorder (OUD) to increase access to buprenorphine. This study aims to explore trends in buprenorphine treatment initiation pre- and post-public health emergency to evaluate changes in the context of X-waiver relaxations and telehealth allowances. MethodsIn a cross-sectional study, all RI residents who filled a buprenorphine prescription at a pharmacy in Rhode Island (RI), Massachusetts, and Connecticut between January 2017 and December 2023 were obtained from the RI Prescription Drug Monitoring Program (PDMP). The study excluded buprenorphine products not approved for OUD treatment from the analysis. Identified individuals had initiated buprenorphine for OUD during the study period if they did not have a prior prescription or if they had >30 days without buprenorphine exposure between their prescriptions. Spearman's rank correlation tests were used to identify significant associations between outcomes and regulation changes. ResultsThe average number of patients dispensed buprenorphine did not significantly change over the study period, however the average number of initiates significantly decreased (ρ = −0.38255, p = .0003). The average number of providers prescribing CII-CV substances in RI has increased 3.4 % over the study period. The average percentage of prescribers in the PDMP prescribing buprenorphine for OUD doubled (ρ = 0.96075, p < .0001). ConclusionThough efforts have been made to increase buprenorphine initiation, buprenorphine initiates remain well below pre-PHE levels. Efforts must continue to eliminate existing barriers to treatment and improve access to individuals seeking treatment.

Hubungan Tingkat Pengetahuan Tentang Vaksinasi Terhadap Kesediaan Vaksinasi Booster COVID-19 Pada Radiografer di Wilayah Jember

Radiographers are at high risk of being infected with COVID-19 related to the most common transmission of COVID-19, so radiographers must be vaccinated. Antibody levels from primary vaccine can only last for 12 to 20 weeks, so booster vaccine is needed. Booster vaccination is one of health behaviors that divided into three domains: cognitive (knowledge), affective (attitudes), and psychomotor (actions). Based on the background above, the authors are interested in researching the relationship between knowledge level about vaccination and willingness to be vaccinated COVID-19 booster among radiographers at Jember. This type of research is a correlational analytic survey with a cross-sectional approach. Population in this research were all radiographers who are members of the Indonesian Radiographers Association (PARI) and active in Jember. The sampling method using total sampling (n=60). Data analysis in this research included editing, scoring, coding, tabulating, univariate analysis, normality test, and bivariate analysis (Rank Spearman Correlation Test) using IBM SPSS Statistics 25 software. Respondent's knowledge level about vaccination showed 46% good, 27% moderate, and 27% less. Respondent’s willingness to be vaccinated COVID-19 booster showed 47% good, 43% moderate, and 10% less. Rank Spearman Correlation Test (Spearman Rho) showed p value or Sig. (2- tailed) of 0.001 and correlation coefficient was 0.43 (+). There is a significant relationship between knowledge level and willingness to be vaccinated COVID-19 booster among radiographers at Jember with moderate correlation strength and unidirectional correlation.