Spastic Diplegic Cerebral Palsy Children Research Articles

The Effect of Rood's Ontogenic Motor Patterns on Trunk Control and Balance in Spastic Diplegic Cerebral Palsy Children

Background: Cerebral palsy (CP) is a non-progressive neuromotor disorder affecting movement, muscle tone, and posture due to brain injury during early development. Effective interventions are essential for improving functional outcomes in children with spastic diplegic CP.Objective: This study aimed to evaluate the effects of Rood's Ontogenic Motor Patterns (ROMP) on trunk control and balance in children with spastic diplegic cerebral palsy.Methods: A single-blinded randomized clinical trial was conducted with 22 children aged 3-10 years, diagnosed with spastic diplegic CP. Participants were randomly assigned to two groups: Group A received Functional Electrical Stimulation with ROMP, and Group B received conventional physical therapy. The intervention lasted five weeks, with three sessions per week. Outcomes were assessed using the Modified Ashworth Scale, Gross Motor Function Measurement Scale (GMFM-88), and Pediatric Berg Balance Scale. Data were analyzed using SPSS 27.Results: Group A showed significant improvement in balance (PBBS: pre 13.81 ± 1.64, post 24.18 ± 4.67; p=0.017) and GMFM-88 scores (pre 9.95 ± 109.50, post 15.73 ± 173.0; p<0.001). Spasticity reduced significantly in the ROMP group (MAS: pre 11.50 ± 126.50, post 7.30 ± 73.00; p=0.010).Conclusion: ROMP significantly improved balance and reduced spasticity in children with spastic diplegic CP compared to conventional therapy, suggesting its potential integration into rehabilitation programs.

Effectiveness of Neurodevelopmental Therapy with Conventional Physiotherapy on Gross Motor Function and Spasticity in Spastic Diplegic Cerebral Palsy Children

Effectiveness of Neurodevelopmental Therapy with Conventional Physiotherapy on Gross Motor Function and Spasticity in Spastic Diplegic Cerebral Palsy Children

Effectiveness of Spider Cage Therapy for Balance Control in Spastic Diplegic Cerebral Children: A Pilot Study

Background: Spastic diplegic cerebral palsy (CP), a neurological disorder that specifically affects the lowerextremities, affects mobility and posture. People with spastic diplegia frequently have balance problems, whichreduces their functional independence and raises their risk of falling. In order to treat balance impairments in thispopulation.Purpose: The aim of the study is to examine novel and alternative treatment approaches that may possibly enhancethe motor function and general quality of life in spastic diplegic cerebral palsy children by examining the efficacyof spider cage therapy for balance control.Methods: 10 children with spastic diplegic cerebral palsy were allocated into developmental and experimentalgroup. The experimental group (n=5) received spider cage therapy and the developmental group (n=5) receivedconventional physiotherapy.Result: This finding shows that the conventional group pre and post-test values by using GMFM (30.2±1.67,34.95±1.58) experimental group pre & post value of GMFM (30.55±5.63,36.95±1.64) with p value<0.0001.Conventional group pre & post-test values by using PBS (9.2±3.11,14.95±4.52) and experimental group pre andpost-test values of PBS (9.75±1.58,16.7±1.78) with a p value <0.0001.Conclusion: The study’s findings suggest that children with spastic diplegia might benefit from balance trainingin a spider cage.

Association Between Calf Muscle Tone, Plantar Surface Area, and Gross Motor Function in Children with Spastic Diplegic Cerebral Palsy.

Children diagnosed with spastic diplegic Cerebral Palsy (CP) usually demonstrate hypertonicity of the lower limb muscles which affects the normal alignments and weight reception by the feet. These impairments could be correlated to the limitations in gross motor function such as standing and walking abilities. Understanding these relationships can contribute to developing more effective rehabilitation strategies and improving overall motor outcomes for affected children. The current study was designed to explore the relationship between plantar surface area, weight distribution on the plantar surface, and gross motor function (namely, standing and walking abilities) in spastic diplegic CP children. Seventy-one spastic diplegic CP children aged 8-14 years joined this cross-sectional study. The Person's correlation coefficient and regression tests were used to assess the correlation between variables, namely, Gross Motor Function (GMFM), Calf Muscle Tone, Plantar surface area (PSA), and Peak pressure on mid and hind feet (PPMF, PPHF, respectively). These variables were assessed using the GMFM-88 scale, Modified Ashworth scale, and foot scan plantar pressure detection system, respectively. The correlation analysis demonstrated a strong to moderate positive correlation between PSA, PPMF, PPHF, and GMFM-D and GMFM-E. Additionally, regression model showed prediction levels equal to 0.791 for the GMFM-D and 0.720 for the GMFM-E categories, respectively. Standing and walking abilities were positively correlated (r ≥.6) with the increased plantar surface area and higher peak pressure on mid and hind feet in spastic diplegic CP. Future longitudinal studies should investigate changes in gross motor function in relation to improvement in plantar surface area and peak pressure values.

Efficacy of TheraTogs on Biomechanical Variables in Spastic Diplegic Cerebral Palsy Children: A Literature Review

Efficacy of TheraTogs on Biomechanical Variables in Spastic Diplegic Cerebral Palsy Children: A Literature Review

Effects of routine physical therapy with and without kinesio taping in improving gross motor function in sitting and standing in spastic diplegic cerebral palsy children

ObjectiveTo determine the effectiveness of Kinesio taping along with routine physical therapy on improving gross motor function in sitting and standing among spastic diplegic Cerebral Palsy children. DesignRandomized controlled trial. SettingsUniversity Teaching Hospital University of Lahore, Lahore. Participants53 participants with diagnosed spastic diplegic cerebral palsy were randomly allocated in control and experimental groups. Intervention26 Participants were treated by kinesio taping which was applied in a criss-cross manner along with routine physical therapy program while the control group (n = 27) received NDT exercise program that comprises of stretching, functional reaching, weight-bearing exercises and walking. Outcome measureGross motor function was assessed using 2 components of Gross Motor Function Classification System (GMFCS-88), i.e., sitting as well as standing at the base line and after every 3rd week for 12 weeks follow up. ResultsIn study and control group the mean score of gross motor function for sitting at baseline was 33.96 ± 3.11 and 31.50 ± 3.32 respectively. After intervention, it changed to 47.70 ± 5.46 and 43.46 ± 1.81 respectively. Mean score for Gross Motor Function calculated at base line in study and control group for standing was 27.37 ± 1.14 and 26 ± 3.01 respectively. At the end of intervention, the score improved to 36.55 ± 4.27 and 33.69 ± 2.46 respectively. ConclusionIn comparison to control group, significant increase in gross motor function of intervention group was seen after the 12 weeks of intervention. In this way, over back muscles the application of kinesio tape in a Criss-Cross manner may be helpful. Also it can be used as an additional approach along with routine physical therapy to improve standing and sitting in spastic diplegic children.

Effectiveness of Sensory Integration Therapy on Functional Mobility in Children With Spastic Diplegic Cerebral Palsy.

Background A set of non-progressive brain abnormalities and nervous system dysfunctions are referred to as cerebral palsy (CP). Due to this,the child's mobility, eyesight, learning, and thought processes are affected. It can evolve before, through birth, or the firstyear of a child's life.The activity through which the brain organizes and analyses external sensations like touch, motion, body awareness, vision, hearing, and gravity is indicated as sensory integration. The use of sensory integration therapy (SIT)necessitates that the sensorimotor exercises target the specific parts of difficulties that the child experiences daily. This study aims tostudy the effectiveness of SIT on functional mobility in children with spastic diplegic CP. Methods In this study, 40 children of CP with spastic diplegic who met the inclusion and exclusion criterion were enlisted and were separated into two groups, with Group A (n=20) receiving SITfor 25 minutes along with conventional physiotherapy for 20 minutes, and Group B (n=20) were given conventional physiotherapy for 45 minutes. A four-week therapy plan was followed. Short sensory profile (SSP) and Gross Motor Function Classification System (GMFCS), Pediatric mini-mental state examination (MMSE), and Modified Ashworth Scale were taken as outcome measures. Results SIT along with traditional treatment is described in the study protocol which aids CP children to improve themselves. Following a four-week protocol, combined therapy of SIT and conventional physiotherapy show an effect on the motor function of the children. After therapy, scores in GMFCS and SSP improved. By using Student's paired t-test, a statistically significant difference was found in GMFCS score at pre and post-test treatment in group A (7.28, p=0.0001) and group B (4.48, p=0.0001),in SSP score at pre and post-test treatment in group A (27.91, p=0.0001) and group B (11.31, p=0.0001), in MMSE score at pre- and post-test treatment in group A (6.89, p=0.0001) and group B (6.32, p=0.0001). The significance threshold was p<0.0001. Conclusion Under the study's experimental conditions, both groups showed substantial improvements in the functional mobility of children. When the efficacy of SIT along with conventional physiotherapy was examined, the impact resulted in a significantly greater improvement in the functional mobility of spastic diplegic CP children.

Hearing and Visual Impairment in Children with Cerebral Palsy, A Study in Tertiary Level Hospital in Bangladesh

Background: Cerebral palsy (CP) is a diagnostic term used to describe a group of motor syndromes resulting from disorders of early brain development. CP remains unexplained in most cases and is typically diagnosed outside the neonatal period. Visual impairment decreases the quality of life and hearing impairment hampers linguistic development. This study aimed to observe the visual and hearing impairment of children with cerebral palsy associated with developmental disabilities. Material Methods: This is a cross-sectional observational descriptive study carried out in the department of Paediatric Neurology CMH Dhaka from March 2018 to February 2022. The participants (N=120) were from birth to 12 years of age. Detailed information was obtained in each case according to protocol. The pediatric neurologist based on the study definition crosschecked the diagnosis. The hearing assessment was done with the help of an Otolaryngologist in the department of Otolaryngology and the ophthalmological evaluation was done with the help of an ophthalmologist of the department of ophthalmology of CMH Dhaka. Hearing impairment, Ophthalmological motor disturbance, and developmental disabilities were correlated. A convenience sampling technique was used in this study. Relevant data were collected from hospital records. All the information was recorded in the fixed protocol. Collected data were classified, edited, coded, and entered into the computer for statistical analysis by using SPSS 2021. Results: In this study, among the 120 children with CP, the mean age of the study was 5.57(SD±3.89) age range of 2-12 years Males were 82(68%) and females were 38(32%), male-female ratio (sex M: F 2.15: 1). Spastic quadriplegia constitutes the predominant group 59(49%), followed by Spastic diplegia 21(18%), Spastic hemiplegia 20(17.5%), dyskinetic CP 09(8%), 7(6%) were mixed CP and 4(3%) were hypotonic CP. Hearing impairment was found in 87 (72%) cases and visual impairment was detected in 92(76%). Among them, the child with Spastic Quadriplegic (83%) and diplegic CP (62%) children had a hearing impairment. Regarding vision, no fix and follow were observed in 69(57%) cases. Among the studied CP child (n=120) 16 children (13.33%) had normal eye finding and 104 (86%) had abnormal eye findings. Refractive error (32.5%) and Squint (19%) were the most common ocular defect among studied patients. Other ocular defect were nystagmus(10%), optic atrophy(12.5%), microphthalmia(10%), corneal opacity(3%), optic hypoplasia(4.1%), cataract(2.5%), pigmentary retinopathy(5%), retro-lental fibroplasias(3.3%) and ptosis(2.5%). In children with hypotonic (athetoid) and mixed CP, almost all (11 of 11) children had visual impairment. Spastic quadriplegic CP children (80%) and Spastic diplegic CP children (90%) had one or more domains of visual impairment. Conclusion: Cerebral Palsy is a non-progressive various form of neurological disorder in children. Early visual screening and hearing assessment can help CP children to minimize mental retardation, learning difficulties, and speech delay.

COMPARATIVE STUDY OF EFFICACY OF CRYOTHERAPY AND MYOFASCIAL RELEASE TECHNIQUE IN CALF MUSCLE SPASTICITY IN SPASTIC DIPLEGIC CEREBRAL PALSY CHILDREN

The greatest substantial consequence of juvenile impairment is cerebral palsy (CP). Spasticity of numerous muscle groupings is common after Central Nervous System damage. Spasticity causes functioning issues. For individuals suffering from CP ankle anomalies seem strongly tied to workable limits. Spastic CP is highest frequent type of CP, which limits child's responsive status and prohibits them from participating in communal activities. Soft tissue mobilisation procedures would be used in variety ways. Cryotherapy is interventional method for stiffness in neurological patients that has narrow advantage. MFR can potentially utilised against spasticity. The focus of this investigation is to evaluate Cryotherapy and MFR influence over calf muscle stiffness in participants who have Spastic Diplegic CP. The survey's goal is to determine efficacy of Cryotherapy and MFR in calf muscle spasticity in Spastic diplegic CP subjects. Thirty individuals suffering spastic diplegic CP were chosen using randomized sampling procedure. The subjects was categorised onto 3 subgroups, each of ten individuals. Cryotherapy was applied to Group A, MFR was applied to B and C Group was applied with combination of cryotherapy and MFR. Both before and after therapy, MAS and goniometry are used to assess calf muscle spasticity and ankle PROM. Overall validity of MAS and PROM comparing before and after in subgroup was determined using Tukey Test. Spasticity was reduced and range of motion was improved (p&lt;0.05) in intra group comparison. Cumulative influence of cryotherapy and MFR is beneficial in reducing calf muscle stiffness in spastic diplegic CP children, as per this investigation.

A Protocol on Effect of Cryotherapy and Myofascial release Technique in Calf Muscle Spasticity of Spastic Diplegic Cerebral Palsy Children

Background: Cerebral Palsy is been one of the developmental disorders affecting the infants brain. Themost common form of Cerebral Paralysis being Spastic Cerebral Palsy affects children functionally andprevents their social functioning. Most of the physiotherapy interventions to treat spasticity are Cryotherapy,Myofascial Release technique. Cryotherapy is effective in reducing Spasticity and some suggest MyofascialRelease Technique is also effective in reducing spasticity. Aim: To find out the effect of Cryotherapy andMyofascial Release Technique in calf muscle of Spastic Diplegic Cerebral Palsy Children. Methods: 30Participants with Spastic Diplegia will be selected on the basis of inclusion as well as exclusion criteria. Thepatients will be evaluated using Modified Ashworth Scale and Modified Tardieu Scale for calf muscle priorto the treatment. The 30 participants will be divided into 3 groups. All the groups will receive Cryotherapy,MFR technique and combined effect of both the techniques separately. The patients will be again evaluatedafter the treatment by using MSA and MTS. Conclusion: This Study Concluded that there may be significantreduction in calf muscle spasticity in spastic diplegic cerebral palsy children by using combine effect of bothCryotherapy and Myofascial Release technique ore one of the method.

Effectiveness of Mother as a Rehabilitative Aid (MARA) Program in the Recovery of Children with Cerebral Palsy-An Assessor blinded Randomized Controlled Trial

Background: Cerebral Palsy is a non-Progressive neuromotor disorder which leads to various impairments and disabilities. There are evidence based Paediatric Physiotherapy approaches for rehabilitating the same. In the recovery of the child literature suggests that home program plays a major role. Objectives; Till date there is a dearth in the literature which quantifies the home program. To provide Mother as a Rehabilitative Aid Program (MARA) to parents of children with cerebral palsy. To compare the effectiveness of MARA with traditional home program. Methodology: Mother as a Rehabilitative Aid (MARA) is a unique program which helps the mothers to be a part of rehabilitative team. It is a quantified tailor made treatment protocol to be effectively used by the mothers. The present study aims to see the effectiveness of MARA over traditional approaches for home program in children with spastic diplegic Cerebral palsy children of age 5 to 10 years. The study design is Assessor Blinded Randomized Controlled Trial. The study population divided into MARA group and Controlled group Results: MARA proved to be effective than traditional home program. T test was used in the statistical analysis. GMFM-88, PBS, Gait parameters all were statistically significant in MARA group than Control group. Discussion: This study is correlated with previous studies and found to give a clear explanation for parent oriented program with quantifiable outcome measures. Conclusion: It can be incorporated in the treatment of cerebral palsy children. Students Communication skills improved, Their Practical skills and service oriented mindset generated. They will get good ideas and can able to feel different problems that parents are facing and they got chance to plan their treatment accordingly. For Parents it generates hope and Trust on our profession. Their involvement will be more when their suffering is shared. Parents came to know different other challenges faced by other parents and they Got to know various other methods to overcome. This study leaves a benchmark for more high quality studies on MARA.

Redesign of Mobility Aids for Spastic Diplegic Cerebral Palsy Children Through Collaboration Among Academics - Medical Devices Industry and User Intitutions

Cerebral palsy (CP) children are part of the neuro disability spectrum in impaired brain function. The etiological understanding of CP children for primary prevention and early treatment can reduce the effects of damage to brain function. CP children with cerebral diplegia are motor developmental disorders caused by damage to the brain characterized by weakness in the lower limbs heavier than the upper limbs. The walker product is designed through a universal design approach to provide as much as possible mobility to CP children in general. A universal design approach to the walker products through the triple helix collaboration included academic, medical devices industry and user institutions. Three subjects with spastic CP cerebral diplegia children underwent gait training using a walker. Gait performance (continuous walking distance, and maximum and comfortable walking speed) and energy expenditure are measured at the end of the 1-week training session. The purpose of the pediatric walker redesign is to facilitate mobilization of the position of the child's body CP in the anterior and posterior positions. The walker design can be removed from the raft back and forth from both sides at the front. At a certain time, the walker can be positioned behind the user according to the recommendations of some physiotherapy practitioners. This design also facilitates the position of CP children in order to be more precise, reducing double support during ambulation and increasing walking speed. The anterior-posterior walker as an ADVANCED walker for CP children provides the most appropriate position because it provides the best gait pattern and consumes less energy.

Efficacy of Cold Therapy and Passive Stretching to Improve Gait in Spastic Diplegic Cerebral Palsy Children

Background One of the most common causes of severe physical disability in childhood is cerebral palsy (CP). Mobility is one of the most important functions to fulfill the activities of daily living. We aimed to determine the effectiveness of cold application to improve the ambulation in spastic diplegic CP children. Materials and Methods In this clinical trial study, 40 subjects were included for the study. They were divided into two groups, namely experimental (n=20), and conventional group (n=20). Study was carried out in Holy Cross College, Department of Rehabilitation Science, Tiruchirappalli, India. Conventional group was given regular conventional training and experimental group was given cold therapy, passive stretching in both legs before training. Both groups received training for 45 minutes, 3 times a week for a duration of 6 weeks. Modified Ashworth scales were used to measure spasticity step length, stride length and Cadences were used to measure the gait parameters, and Timed Up and Go test (TUG) was used to measure the functional activity. Results Significant effect was observed in decrease in spasticity, there was increase in gait parameters and timed up and go test in two studied groups. The post-test mean values of all the variables of cold therapy, passive stretching in experimental group are improved compared with that of conventional group. The experiment improved with stride length, step length, cadence, timed up and go test and Modified Ashworth scale (p<0.05). Conclusion Based on the derived results, there was decreased tone in spastic muscles and improvement in gait parameters and functional ability in children with diplegic CP after application of cold therapy and passive stretching.

Effect of push-up exercises on hand grip strength in diplegic children.

Background: Diplegia is a spastic form of cerebral palsy with lower limbs more affected than upper limbs. The hand is effector organ of upper extremity for support, manipulation and prehension. Purpose: The purpose of this study is to determinethe effect of push-up exercises on hand grip strength in spastic diplegic cerebral palsied children. Subjects and methods: Sixty spastic diplegic children with age ranged from 4 to 7 years from both sexes participated in this study. They were chosen from physical therapy department, Mubarak Central Hospital, Giza Governorate, Egypt. Subjects were divided randomly into three groups A, B and C, of equal number [twenty patients each]. Each patient was evaluated pre and post-treatment individually by using Peabody Developmental Motor Scale (PDMS-2) to determine standard scores of grasping subtest and age equivalent for fine motor activities and Baseline pneumatic squeeze handheld dynamometer to detect maximum hand grip strength. Control group (A) received traditional physiotherapy program for spastic diplegia and the two study groups (B and C) received the same traditional physiotherapy program in addition to push-up exercises on stable surface for group B in form of wide base push-up exercises, while group C in form of narrow base push-up exercises. The treatment protocol was conducted for three successive months and six times per week. Results: The results of this study revealed significant improvement in hand grip strength, standard scores of grasping and age equivalent in the three groups equally. Conclusion: Conventional physiotherapy program is effective as push-up exercises in improving hand function in spastic diplegic children. Push-up exercises only do not add benefits on hand grip strength.

Relation of Hip Anteversion, Knee Flexion Angle and Balance in Spastic Diplegic Cerebral Palsied Children

Abstract Background: Torsional disorders and flexed knee gait are frequently pronounced in spastic diplegic cerebral palsy (CP) children. Identification of these anomalies is essential as they affect postural control

Effect of treadmill training with partial body weight support on spine geometry and gross motor function in children with diplegic cerebral palsy

Abstract Back ground: Cerebral palsy children suffer from neuromuscular and musculoskeletal problems such as spasticity, muscle contractures, bony deformities, incoordination and muscle weakness that interfere with motor function. The aim of this study was to evaluate the effect of treadmill training with partial body weight support on spine geometry and gross motor function in spastic diplegic cerebral palsy children. Methods: 31 children with spastic diplegia (5-7 years) were recruited and randomly allocated to control group (15) and study group (16). Of these, 30 children completed training and testing. Both groups received a specially designed therapeutic exercise program. The study group additionally received treadmill training with partial body weight support (30% relief of total body weight). Treatment was provided 3d/w for 3 successive months. Assessment was performed before and after intervention. Trunk imbalance, pelvic tilt scores using formatric instrumentation system were recorded. Gross motor function (standing and walking) scores using gross motor function measurement scale were recorded. Results: children in both groups showed a significant improvements in the mean values of all measured variables post-treatment (p

Study on Efficacy of Task Oriented Training on Mobility and Balance among Spastic Diplegic Cerebral Palsy Children

Study on Efficacy of Task Oriented Training on Mobility and Balance among Spastic Diplegic Cerebral Palsy Children

USING BIODEX BALANCE TRAINING SYSTEM TO IMPROVE POSTURAL CONTROL IN SPASTIC DIPLEGIC CEREBRAL PALSY CHILDREN: A BIOMECHANICAL PERSPECTIVE

Background : Spastic diplegic cerebral palsy (SDCP) is the most common form of cerebral palsy.It is characterized by multiple postural disorders.Objective: The aim of this study was to evaluate the effect of postural control training using Biodex balance system on back geometry. Method: Forty SDCP children (22 boys and 18 girls) in the age ranged from 5 to 7 years old were randomly allocated into two groups of 20 children each. All children were assessed before and after the treatment program by the formetric system. The study group received postural control training using Biodex balance system and therapeutic exercise program. The control group received only the therapeutic exercise program. Results: The results revealed significant improvement in all post treatment mean values which was higher for the study group. Conclusion: Postural control training using Biodex balance system can be used to improve postural alignments in children with spastic diplegia.

Balance training versus reciprocal electrical stimulation on knee joint alignment in spastic diplegic cerebral palsy children

Spastic diplegia is the most common pattern of motor impairment in patients with cerebral palsy (CP) because of a number of deficits, including poor muscle control, weakness, impaired balance, and spasticity, which cause malalignment of the knee joint during standing and walking. This study aimed to evaluate the effect of balance training (BT) versus reciprocal electrical stimulation (RES) of knee extensors and flexors on knee joint alignment in spastic diplegic CP children. Thirty children with spastic diplegic CP of both sexes were selected, ranging in age from 6 to 8 years. Children were divided randomly into two equal groups (I and II). Evaluation was performed before and after 12 weeks of treatment using a digital goniometer to measure range of motion of the knee joint, tape measurement to measure the distance between the buttock and the heel, and gross motor functional measure to provide functional evaluation of standing and walking abilities. Group I received a BT program on the Biodex balance system in addition to a selected physical therapy program. Group II received RES of knee extensors and flexors in addition to the same selected physical therapy program. Both BT and RES for 12 weeks in spastic diplegic CP seem to yield a beneficial and statistically significant increase in adjusting knee alignment and improving the functional abilities in standing and walking (P < 0.05). However, BT seems to exert a more beneficially and statistically significant effect than RES. BT and RES have a significant effect on improving knee alignment in spastic diplegic CP children.

LOCOMOTOR TREADMILL TRAINING PROGRAM USING DRIVEN GAIT ORTHOSIS VERSUS MANUAL TREADMILL THERAPY ON MOTOR OUTPUT IN SPASTIC DIPLEGIC CEREBRAL PALSY CHILDREN

Abstract Purpose: This study intended to understand and compare the effect of loco-motor treadmill training program using robot-assisted gait therapy (Driven gait-orthosis DGO) and manual treadmill therapy on motor function in children with spastic diplegic cerebral palsy on their gross motor skills related to walking speed, ambulation and endurance. Subjects and Methods: Twelve spastic diplegic cerebral palsy children with the age under 5 years were participated in different ambulation training 3 times per week for 30 - 40 minutes sessions consisting of 2 different treadmill walking programs, for 10 weeks, and were tested pre and post intervention. The outcome measures included were; a timed 10-m walk test, ground walking speed, walking distance, and balance which were measured before and after treatment. Results &amp; Conclusion: The results of this study suggests preliminary findings that children with CP under the age of 5 years can benefit their gross motor function, gait variables after intensive ambulation training using Driven gait orthotis (DGO).