Spain October Research Articles

ESGCT 27th Annual Congress In collaboration with SETGyc Barcelona, Spain October 22–25, 2019 Abstracts

Xenotransplantation of transgenic porcine pancreatic islets offers a promising alternative source to circumvent current limitations posed by the scarcity of allogeneic donors. We have investigated the feasibility to generate tissue engineered SLA silenced islet cell clusters (ICC) to decrease xenogeneic immune responses Pancreatic islets single cell suspensions were generated by enzymatic digestion of porcine ICCs. Single cells were silenced for SLA expression by lentiviral vectors encoding for Nanoluciferase as reporter gene and for short hairpin RNAs targeting beta2-microglobulin or class II transactivator, respectively. SLA transcripts were evaluated by real-time PCR and protein levels by flow cytometry and fluorescence microscopy analyses. The effect of SLA silencing was evaluated in human T and NK cell cytotoxicity assays. SLA-silenced pancreatic beta-cells were then reassembled into ICCs in stirred bioreactors. SLA class I silencing reached a level of up to 84% and class II by up to 50% on pancreatic islet cell. Silencing SLA expression did not affect cell viability and the insulin-producing beta-cell phenotype. Xenogeneic T-cell immune responses (p < 0.05) as well as antibody-mediated cellular-dependent immune responses (p < 0.01) were significantly decreased. Silencing SLA class I expression did not increase susceptibility to NK-cell cytotoxicity. In stirred bioreactors, tissue engineered islets showing the typical 3D-structure and morphology of ICC were assembled from SLA-silenced pancreatic cell suspensions. These data shows the feasibility to generate low immunogenic porcine ICC from transgenic pigs after single cell engineering and post-transduction islet reassembling that might serve as a robust alternative to allogeneic pancreatic islet cell transplantation.

Abstracts of the 21st Congress of the Spanish Society for Surgical Research Madrid, Spain October 2015.

Abstracts of the 21st Congress of the Spanish Society for Surgical Research Madrid, Spain October 2015.

Abstracts of the XXXIII Symposium of ASESCU.Calahorra Spain October 30 - 31 2008.

The annual Congress of the Spanish Association of Cuniculture (ASESCU) was held in Calahorra (La Rioja) on &nbsp;30-31 st October of 2008. The 33 th &nbsp;edition was devoted to study different strategies to enhance the farm profitability. &nbsp;The high increment in the feeding and the low price of the meat have been the main responsible of the decrease in &nbsp;the profitability in the last 2 years. Different possibilities to reduce the feed conversion ratio (FCR) both in fatteners &nbsp;and females were discussed in two sessions. Furthermore, a total of 15 communications were presented in 5 working &nbsp;sessions: Meat quality in commercial or wild rabbits, Genetic and Reproduction, with a focus on new selection &nbsp;criteria and semen quality, Management and economy, with a study of the costs, Nutrition, with strategies to reduce &nbsp;mortality and Pathology, with references to different pathologies.&nbsp;

The European Course of Neuroradiology (ECNR) Goes Diagnostic and Interventional

The European Course of Neuroradiology (ECNR) was set up in 1983 under the aegis of the European Society of Neuroradiology (ESNR) founded in 1969. Besides the major aim of educating young doctors to become neuroradiologists, this course was also necessary to adhere as much as possible to the European regulations for academic education programs with the precise aim of being recognized as a sub-speciality within the European Union of Medical Specialists (UEMS). It was meant to be a dynamic initiative flanking the existing European Course of Neurosurgery (ECNS) thereby creating a true European neuroradiological profile. During the past years, our speciality has undergone many changes, the most obvious of which being that neuroradiology is nowadays widely accepted as both a diagnostic and interventional speciality. Guidelines for training and practice were established and specifically targeted the above-mentioned dual aspects of neuroradiology. Since March 2008 our goal of becoming a subsection within the UEMS has been rea-ched, further stressing the need to provide a European Course of Neuroradiology that adheres more obviously to our training guidelines which are both diagnostic and interventional. Under the directorate of Prof. Radu from Basel who organized the 8th and 9th cycles of the ECNR with huge success in Basel during the past four years, the first steps towards the dual aspect of the ECNR had been undertaken. With the 10th cycle we plan to continue on this path and even further stress our “interventional” educational mission with the ECNR being the course of the European Society for both diagnostic and interventional neuroradiology. The scientific content of the 10th Cycle will provide unique material and will take into very close account the standards and guidelines for residency training in clinical neuroradiology (diagnostic and interventional) included in the European Charter on Training of Medical Specialists in the European Union (EU), a document needed by the European Commission with the principal aim of standardizing training programs in the countries of the EU and associated member states. Different from the usual “refresher courses”, the 10th Cycle is mainly directed toward in-training or established neuroradiologists and has the following main scientific objectives and characteristics: 1) Impart teaching-based lectures and workshops, rather than academic-type conferences in order to transmit rather than deliver information. 2) Provide the students with scientific and conceptual lectures, which they are unlikely to obtain in their own countries, or from general radiology courses or textbooks. 3). Acquire basic neuroscience and clinical core knowledge. 4) Provide theoretical bases of present and future clinical practices and research in diagnostic and interventional neuroradiology. 5) Impart highly interactive diagnostic, interventional and mixed-type neuroradiological workshops. The interventional topics are chosen in close collaboration with the World Federation of Interventional and Therapeutic Neuroradiology (WFITN) to assure the highest academic standards and to adhere to the Training Path of Interventional Neuroradiology consisting basic and theoretical knowledge, practical experience, and skill training. All topics are discussed by the board of the European Course of Neuroradiology comprising the course directors, the EBNR and ten established diagnostic and interventional neuroradiologists from Europe. Because of the broad coverage of interventional and diagnostic neuroradiology, the 10th cycle has also been approved by the European Society of Radiology (ESR) as being a modular part of the European School of Radiology (ESOR), further emphasizing its role as the European Course of Neuroradiology. The following topics have been chosen for each of the four courses to be covered in six full days of lectures and workshops: 1) Embryology/Anatomy/Malformations/Genetics (Tarragona, Spain October, 2008). 2) Tumours (Rome, Italy March, 2009). 3) Vascular Diseases (Tarragona, Spain October, 2009). 4) Trauma/Degenerative/Me-tabolic/ Inflammatory Diseases (Rome, Italy March 2010). The didactic credits provided for the course are intended to comply with the regulations of academic education programs. The cycles are structured in four modules held over two years. At the end of each module a certificate reporting CME credits is issued after completing a written test. Upon completion of all four modules (one entire cycle) participants can apply to take a final oral examination. If they pass, a certification as a qualified neuroradiologist (European Qualification in Neuroradiology EQNR) will be issued jointly by ESNR and EBNR. This EQNR is part of the European Qualification, as required by the UEMS for Specialities. We hope that with the 10th cycle we will be able to step into the large footsteps of the past courses and add our own marks to the education of future neuroradiologists. We look forward to meeting you in Tarragona and in Rome.

The European Course of Neuroradiology (ECNR) Goes Diagnostic and Interventional

The European Course of Neuroradiology (ECNR) was set up in 1983 under the aegis of the European Society of Neuroradiology (ESNR) founded in 1969. Besides the major aim of educating young doctors to become neuroradiologists, this course was also necessary to adhere as much as possible to the European regulations for academic education programs with the precise aim of being recognized as a sub-speciality within the European Union of Medical Specialists (UEMS). It was meant to be a dynamic initiative flanking the existing European Course of Neurosurgery (ECNS) thereby creating a true European neuroradiological profile. During the past years, our speciality has undergone many changes, the most obvious of which being that neuroradiology is nowadays widely accepted as both a diagnostic and interventional speciality. Guidelines for training and practice were established and specifically targeted the above-mentioned dual aspects of neuroradiology. Since March 2008 our goal of becoming a subsection within the UEMS has been rea-ched, further stressing the need to provide a European Course of Neuroradiology that adheres more obviously to our training guidelines which are both diagnostic and interventional. Under the directorate of Prof. Radu from Basel who organized the 8th and 9th cycles of the ECNR with huge success in Basel during the past four years, the first steps towards the dual aspect of the ECNR had been undertaken. With the 10th cycle we plan to continue on this path and even further stress our “interventional” educational mission with the ECNR being the course of the European Society for both diagnostic and interventional neuroradiology. The scientific content of the 10th Cycle will provide unique material and will take into very close account the standards and guidelines for residency training in clinical neuroradiology (diagnostic and interventional) included in the European Charter on Training of Medical Specialists in the European Union (EU), a document needed by the European Commission with the principal aim of standardizing training programs in the countries of the EU and associated member states. Different from the usual “refresher courses”, the 10th Cycle is mainly directed toward in-training or established neuroradiologists and has the following main scientific objectives and characteristics: 1) Impart teaching-based lectures and workshops, rather than academic-type conferences in order to transmit rather than deliver information. 2) Provide the students with scientific and conceptual lectures, which they are unlikely to obtain in their own countries, or from general radiology courses or textbooks. 3). Acquire basic neuroscience and clinical core knowledge. 4) Provide theoretical bases of present and future clinical practices and research in diagnostic and interventional neuroradiology. 5) Impart highly interactive diagnostic, interventional and mixed-type neuroradiological workshops. The interventional topics are chosen in close collaboration with the World Federation of Interventional and Therapeutic Neuroradiology (WFITN) to assure the highest academic standards and to adhere to the Training Path of Interventional Neuroradiology consisting basic and theoretical knowledge, practical experience, and skill training. All topics are discussed by the board of the European Course of Neuroradiology comprising the course directors, the EBNR and ten established diagnostic and interventional neuroradiologists from Europe. Because of the broad coverage of interventional and diagnostic neuroradiology, the 10th cycle has also been approved by the European Society of Radiology (ESR) as being a modular part of the European School of Radiology (ESOR), further emphasizing its role as the European Course of Neuroradiology. The following topics have been chosen for each of the four courses to be covered in six full days of lectures and workshops: 1) Embryology/Anatomy/Malformations/Genetics (Tarragona, Spain October, 2008). 2) Tumours (Rome, Italy March, 2009). 3) Vascular Diseases (Tarragona, Spain October, 2009). 4) Trauma/Degenerative/Me-tabolic/ Inflammatory Diseases (Rome, Italy March 2010). The didactic credits provided for the course are intended to comply with the regulations of academic education programs. The cycles are structured in four modules held over two years. At the end of each module a certificate reporting CME credits is issued after completing a written test. Upon completion of all four modules (one entire cycle) participants can apply to take a final oral examination. If they pass, a certification as a qualified neuroradiologist (European Qualification in Neuroradiology EQNR) will be issued jointly by ESNR and EBNR. This EQNR is part of the European Qualification, as required by the UEMS for Specialities. We hope that with the 10th cycle we will be able to step into the large footsteps of the past courses and add our own marks to the education of future neuroradiologists. We look forward to meeting you in Tarragona and in Rome.

Conference announcement and call for papers touch, blindness, and neuroscience Madrid, Spain october 16–18, 2002

Conference announcement and call for papers touch, blindness, and neuroscience Madrid, Spain october 16–18, 2002

Abstracts from the Fourth Meeting of the Spanish Pancreatic Club at Madrid, Spain October 25 and 26, 1996

Abstracts from the Fourth Meeting of the Spanish Pancreatic Club at Madrid, Spain October 25 and 26, 1996

Spain's October Revolution and the Rightist Grasp for Power

In October 1934 a general strike broke out in Madrid, the bourgeois left-liberal government in Barcelona declared the independence of Spain's four Catalan provinces and, for two weeks, revolutionary miners in Asturias fought a desperate battle against the Spanish army. These events were the response of various left-wing elements to the proposed entry into the cabinet of three ministers from the authoritarian Catholic party, the CEDA.1 Since, in the last elections in November 1933, the CEDA had emerged as the largest single grouping in the Cortes, these actions have been widely interpreted as a deliberate rejection by the left of the rules of democratic co-existence. In this view, the left's egoistic extremism in attempting to take by violence what had been denied them by the vote made the right despair of the possibilities of legality.2 Accordingly, they were driven to defend their interests by other means.