Cartography, or geographical visualization of disease is an essential aspect of the field of GeoHealth, yet there is limited guidance on the visualization of spatiotemporal disease maps. In order to adequately contribute to understanding disease outbreaks, disease maps should be crafted carefully and according to relevant cartographic guidelines. This article aims to increase the understanding of space-time visualization techniques that are relevant to the field of GeoHealth, by providing a step-by-step framework for the creation of space-time disease visualizations. This study introduces a systematic approach to spatiotemporal disease mapping by integrating operations from the Generalized Space Time Cube (GSTC) Framework with established cartographic symbology guidelines. This resulted in an overview table that contains both the relevant GSTC operations and cartographic guidelines, as well as a step-by-step procedure that guides users through the process of creating informative spatiotemporal disease maps. The practical application of this step-by-step procedure is demonstrated with an example using Dutch COVID-19 data. By providing a clear, practical step by step procedure, this study enhances the capacity of public health professionals, policymakers, and researchers to monitor, understand, and respond to the spatial and temporal dynamics of diseases.