South America Research Articles

A new species of Cis Latreille (Coleoptera: Ciidae) widespread in Brazil but with similarities to the African fauna

Cis caramelo sp. nov. is described based on specimens collected in the North, Northeast, and Southeast Regions of Brazil. It stands out for being more similar to the species of Cis Latreille from Africa than South America. Cis caramelo sp. nov. fits into the Cis neserorum species-group, being morphologically similar to Cis aster Souza-Gonçalves & Lopes-Andrade, but differing in the presence of a sex patch on the first abdominal ventrite of males and in the morphology of the aedeagus, with a wide tegmen lacking acute tips on the sides and a penis wide and sclerotized at its basal portion, abruptly narrowed and membranous apically. Brief descriptions and images of immatures of C. caramelo sp. nov. are also provided.

Genetic architecture underlying the parallel evolution of leaf ecomorphs in Viburnum

Abstract In a neotropical lineage of the plant clade Viburnum (Adoxaceae) several leaf ecomorphs evolved independently and repeatedly as the group radiated through cloud forests of North and South America. Here, we focus on one pair of co-occurring sister species within this radiation with strongly contrasting leaf morphotypes and document the presence of phenotypically diverse and genetically admixed hybrid individuals in multiple hybrid swarms. Hybrid phenotypes are generally intermediate in form, but sometimes show parental or entirely novel and transgressive combinations of leaf traits, suggesting that parental leaf ecomorphs can be functionally and genetically dissociated. We used admixture mapping within hybrid swarms to investigate the genetic architecture of key traits comprising these leaf ecomorphs and uncovered loci proximal to known genes implicated in leaf development, including some that may alter multiple leaf traits simultaneously, potentially facilitating the emergence of leaf syndromes. We conclude that the shared genetic architecture underlying some traits, such as leaf size and marginal teeth, could promote the repeated evolution of these traits in concert, while low levels of genetic linkage between other leaf traits supports the hypothesis that selection promoted the repeated assembly of particular combinations of leaf traits as Viburnum radiated throughout the neotropics.

Genetic diversity of Theileria spp. in deer (Artiodactyla: Cervidae) from Brazil.

Babesia spp. and Theileria spp. are tick-borne apicomplexan protozoa that can cause disease in animals and humans. Deer are considered reservoirs for a wide variety of Piroplasmida species, including some potentially zoonotic. This study aimed to investigate the occurrence and genetic diversity of piroplasmids in wild deer sampled in four Brazilian states (São Paulo, Mato Grosso do Sul, Paraná and Goiás). For this purpose, extracted DNA samples from 181 deer buffy coat samples (138 Blastocerus dichotomus, 26 Subulo gouazoubira, 4 Mazama jucunda, 3 Mazama rufa and 10 Ozotocerus bezoarticus) were subjected to a nested PCR (nPCR) assay based on the 18S rRNA gene in order to perform a screening for piroplasmids and characterized based on the near-complete 18S rRNA, hsp70 and cox-3 genes. As a result, 75.14% (136/181) samples were positive for piroplasmids. Of these, 108 (79.41%), 101 (74.26%) and 67 (49.26%) were positive to near complete 18S rRNA, hsp70 and cox-3 genes, respectively. Phylogenetic analyses based on three molecular markers showed similar topology to each other. All sequences obtained in the present study were positioned into the Theileria sensu stricto clade, forming a distinct clade, albeit close to T. cervi. Most sequences grouped together into a large clade divided into subclades, which were often related to deer genus/species, showing that Theileria lineages seemed to show specificity according to deer genus/species. Two 18S rRNA sequences (one obtained from S. gouazoubira and another from M. jucunda) were positioned into a different clade, apart from other sequences detected in this study, indicating that different species of Theileria occur in deer from Brazil. Two subclusters were observed in the phylogenetic analysis based on the hsp70 gene: the first containing only sequences detected in marsh deer and the second grouping sequences detected in brocket deer (Mazama spp. and S. gouazoubira). The latter was also divided into smaller clades that grouped Theileria genotypes according to deer species (M. jucunda, M. rufa and S. gouazoubira). This study provides the first molecular evidence of Theileria infection in M. jucunda, as well as co-infection by distinct Theileria (sub)species/genotypes in the same deer was evidenced. Finally, this study expanded the knowledge on the diversity of Theileria spp. infecting deer from South America.

Cascabela Thevetia Ethnobotanical, Phytochemistry, Pharmacological Activities and Medicinal Uses: A Detailed Study

There are a few different names for the member of the Apocynaceae family known as Cascabela thevetia. Some of these names include digoxin, lucky nut, and yellow oleander. The lovely and evergreen Cascabela thevetia is a dicotyledonous shrub that is known for its evergreen nature. There are a number of countries in Central and South America, as well as a number of Asian nations, where the Cascabela thevetia plant is indigenous. These countries include India and Sri Lanka. The Cascabela thevetia plant has been found to have a wide variety of secondary metabolites, such as alkaloids, flavonoids, steroids, terpenoids, tannins, saponins, and cardiac glycosides. These plants include a number of cardiac glycosides, including neriifolin, thevetin A, thevetin B, and oleandrin, and each and every one of them is dangerous. The leaves of the plant are used in traditional medicine not just for their alleged medicinal benefits, but also for their diuretic and cardiotonic effects. The pharmacological activity of a number of plant components, including seeds, flowers, bark, fruits, and leaves, has been reported in a number of different experiments. It is common for T. peruviana to be the cause of toxicological emergencies in tropical and subtropical climates all over the world. Numerous cardiac glycosides, including neriifolin, oleandrin, thevetin A, and thevetin B, are discovered in this potentially hazardous plant. These glycosides are only a few examples. After consuming oleander, some of the symptoms that may manifest themselves include hyperkalaemia, nausea, vomiting, diarrhoea, and abdominal pain. Oliander can also cause diarrhoea. The purpose of this review is to provide a comprehensive data collection that includes information on morphology, cultivation and propagation, distribution, phytochemistry, traditional uses, and pharmacological qualities.

Inside the November 2024 Issue

Dear Readers, We are thrilled to bring you the second issue of the ninth volume of POCUS Journal. Published since 2016, POCUS Journal is the only multi-disciplinary, peer-reviewed, POCUS-focused journal that is free for authors and readers alike. This issue features a variety of POCUS articles from around the world: from North America, South America, Europe, Asia, and even Australia. In addition to novel cases with striking POCUS images and video clips, this issue boasts a great deal of educational research at all levels: Danila et al. (page 80) report on their study of how POCUS can augment a medical student preclinical cardiovascular course while Piro et al. (page 93) studied the impact of just-in-time POCUS curriculum on internal medicine residents; Janjigian et al. (page 109) studied the longitudinal impact of a faculty POCUS training course. POCUS is a powerful tool with a wide range of applications: for example, it can be used both to diagnose musculoskeletal conditions (Doblinger et al. page 15 and Mack et al. page 27) and to treat musculoskeletal conditions (Bowling et al page 12, and McCreary et al. page 30). POCUS can also be used to predict heart failure readmission (Malagón et al. page 125). We are so excited to showcase pivotal POCUS scholarship like this in the November issue. I hope you enjoy this issue of POCUS Journal as much as I have. A huge thank you to our authors, editorial board, and publisher. Sincerely , Benjamin T. Galen, MD Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA

Self-Reported Unfair Police Stops and Skin Tone, Ethnic Origin, and Citizenship Status among Latino Adults

While a growing literature has documented vast ethnoracial inequalities tied to the occurrence and outcomes of police contact, less research has examined the patterning of perceived unfair police stops among Latino populations. The present study relies on insights from tri-racial stratification theory to examine associations between perceived unfair police stops and skin tone, ethnic origin, and citizenship status among Latino adults. Data come from the Pew Research Center’s nationally representative 2021 National Survey of Latinos ( n = 3,019). We regress whether a respondent perceived being stopped unfairly by police in the past year on the Yadon-Ostfeld Skin Color Scale (i.e., 1–10, 10 = Darkest), ethnic origin (i.e., Puerto Rican, Cuban, Dominican, Salvadoran, Spaniard, Central American, South American, or other), and citizenship status (i.e., U.S. citizen or not). Results showed that having a darker skin tone and U.S. citizenship were associated with higher odds of experiencing a police stop perceived as unfair. Latinos with the darkest skin tones had nearly a one in five chance of a perceived unfair police stop. Average probabilities of a perceived unfair stop were higher for Puerto Ricans, Cubans, and Salvadorans than others followed by Mexicans/Chicanos. Dominicans’ probability was lower than five of the eight other groups. Findings identify heterogeneity among Latino populations such that variation in skin tone, citizenship status, and ethnic origin independently factor into self-reported unfair police stops. Research examining ethnoracial disparities in criminal legal contact and its consequences would benefit from more fully disaggregating panethnic groups.

Feed-induced hypersalivation in horses from Austria, Germany and Switzerland.

While previous reports come mostly from the southern Americas, several outbreaks of hypersalivation in horses were observed in Middle Europe from 2016 to 2018. To describe feed-induced hypersalivation in European horses. Analysis of feedstuffs. Veterinarians and horse or stable owners were encouraged to submit feedstuffs from case outbreaks of hypersalivation in which, infectious diseases or other systemic causes of the syndrome were ruled out and intoxication was suspected. Feedstuff analysis was performed, including gross examination, microscopic analysis of fine particles, and for hay and forage mycological culturing and mycotoxin testing. Eleven case outbreaks were investigated. Typical clinical findings in the horses were either foamy saliva around the mouth or serous salivation with puddles forming on the ground. Some horses also showed lesions of the gingival mucosa and/or the tongue. Foamy hypersalivation, sometimes combined with lesions of tongue and/or gingiva, was associated with finding of ergot sclerotia and ergot alkaloids in hay or pasture plants (ergocornin and ergocorninin having the highest concentrations). Serous hypersalivation with massive loss of fluid was associated with the fungus Rhizoctonia spp. As indicated by the detection of traces of swainsonine, mycotoxin production on the forage was seen as likely cause. The cessation of clinical signs took days to weeks after diet change, probably depending on the duration, type and amount of toxin intake. Small number of case outbreaks, records of clinical findings and horses' management were incomplete and were reported by horse owners. Hypersalivation due to mycotoxins in the feed has become an emerging problem for horses in middle Europe.

Terminal Pleistocene–Early Holocene human occupation in north-central Chile

While a clear human presence may be recognised in the Andes by 12 000–11 000 cal BP, most archaeological research has focused on occupation of the Andean highlands. To understand the initial occupation of inland areas of South America, the authors consider regional connections and spatial exploitation strategies of hunter-gatherers highlighted in a recent survey of Andean sites. Focusing on north-central Chile, artefacts and radiocarbon dates from three rock shelters suggest sporadic and brief occupation during the Terminal Pleistocene–Early Holocene. Co-occurrence of marine and montane resources, the authors argue, demonstrates a strategy of high mobility and local adaptation in early Andean occupation, using rock shelters as landmarks to navigate and learn new landscapes.

Extreme Precipitation Events During the Wet Season of the South America Monsoon: A Historical Analysis over Three Major Brazilian Watersheds

Most of South America, particularly the region between the southern Amazon and southeastern Brazil, as well as a large part of the La Plata Basin, has its climate regulated by the South American Monsoon System. Extreme weather and climate events in these areas have significant socioeconomic impacts. The Madeira, São Francisco, and Paraná river basins, three major watersheds in Brazil, are especially vulnerable to wet and drought periods due to their importance as freshwater ecosystems and sources of water for consumption, energy generation, and agriculture. The scarcity of surface meteorological stations in these basins makes meteorological studies challenging, often using reanalysis and satellite data. This study aims to identify extreme weather (wet) and climate (wet and drought) events during the extended wet season (October to March) from 1980 to 2022 and evaluate the performance of two gridded datasets (CPC and ERA5) to determine which best captures the observed patterns in the Madeira, São Francisco, and Paraná river basins. Wet weather events were identified using the 95th percentile, and wet and drought periods were identified using the Standardized Precipitation Index (SPI) on a 6-month scale. In general, CPC data showed slightly superior performance compared to ERA5 in reproducing statistical measures. For extreme day precipitation, both datasets captured the time series pattern, but CPC better reproduced extreme values and trends. The results also indicate a decrease in wet periods and an increase in drought events. Both datasets performed well, showing they can be used in the absence of station data.

Toxicological assessment of the effects of CuCl2 and CuO nanoparticles on early developmental stages of the South American toad, Rhinella arenarum by standardized bioassays.

The release in aquatic environments of emergent contaminants such as copper oxide nanoparticles (CuO-NPs) has generated concerns on their short- and long-term toxicity and the potential risk for more vulnerable animal groups, such as amphibians. In this sense, the aim of this work was to evaluate the toxicity of CuO-NPs in comparison with its respective salt (CuCl2) in embryos and larvae of a native amphibian, Rhinella arenarum, by acute (96h) and chronic (504h) standardized bioassays. Lethality and sublethal effects such as developmental, morphological, and ethological alterations were assessed in a wide range of concentrations (0.001-100mg/L). Neurotoxic effects by acetyl (AChE) and butyrylcholinesterase (BChE) activity levels and changes in the lipid content were also assessed at sublethal concentrations. Results showed that CuCl2 caused higher lethality than CuO-NPs in both developmental periods. Embryos were more sensitive than larvae with LC50-96h = 0.080mg CuCl2/L and 1.26mg CuO-NPs/L and 0.21mg CuCl2/L and 20.17mg CuO-NPs/L, respectively. At acute exposure, embryos exhibited several developmental abnormalities such as developmental delay, edema, axial flexure, and microcephaly. Larvae presented spasmodic contractions and weak movements. Regarding neurotoxicity, a significant increase in AChE activity at low concentrations as well as an inhibition of BChE activity at all tested concentrations was evidenced for both substances at acute exposure. Moreover, an increment in phospholipid and triglyceride levels was observed at the highest concentration of CuO-NPs (10mg/L) at chronic exposure. The chromatographic separation of lipids showed no apparent differences in acylglycerols and free fatty acid bands, between the treatments and the control. The differences in toxicity between CuO-NPs and CuCl2 could be due to structural and physicochemical characteristics that influence their bioavailability and toxicity. Considering the exponential growth in the production and use of these substances, it is expected that the levels of contamination will rise considerably in the future, so that wildlife, particularly aquatic organisms, will be more increasingly exposed, representing a potential risk for their populations.

A new species of Coeliaria Mulsant, 1850 (Coleoptera: Coccinellidae: Coccinellinae: Chnoodini) from northeastern Brazil

The ladybird genus Coeliaria Mulsant, 1850 (Coleoptera: Coccinellidae: Coccinellinae: Chnoodini) includes five species distributed in South America. We describe and illustrate a new species, Coeliaria almeidae sp. nov., found in Casa Nova, Bahia, Brazil. It is the second found in the Northeast Region of Brazil and the first in the Caatinga. We provide an updated identification key for all species of Coeliaria and present new notes on morphology, host plants and prey records. We also provide new records of Coeliaria bernardinensis (Brèthes, 1925).

Historical and ongoing hybridisation in Southern South American grassland species.

Natural hybridisation in plants can impact genetic and morphological diversity, including the emergence of better-adapted new populations and the potential extinction of some lineages involved in this intricate process. Under progressive global warming, species often need to migrate to newly suitable areas, which may be an additional challenge for species with low dispersal ability. Throughout the search for new environments, previously allopatric lineages can come into secondary contact and eventually hybridise if reproductive isolation is incomplete. Here, we focused on two taxa representing the natural herbaceous component of southern South American lowland grasslands. We aimed to evaluate the impact of contact zones and potential hybridisation on the evolutionary relationships and population dynamics. We used single nucleotide polymorphisms and morphological data of multiple individuals from allopatric and contact zones between taxa to shed light on hybridisation patterns and demographic scenarios. Our results indicated that the contact zones impact taxa's genetic and morphological diversity, and each contact zone had different patterns of genetic diversity and morphology, constituting stable populations that potentially reflect hybridisation events occurring at distinct evolutionary times.

Jurassic magmatism in the Garzón region of the Colombian Andes: insights from whole-rock geochemistry and zircon isotope analysis of granites and subvolcanic rocks

ABSTRACT New whole-rock geochemical and zircon U – Pb dating and Lu – Hf isotope data are presented for the Garzón granites and related subvolcanic rocks, which formed during widespread Jurassic arc magmatism in the Colombian Andes. This magmatism resulted from the subduction of a proto-Pacific plate under the NW South American margin. Our data indicate that the granitic and related rocks of the Algeciras, Altamira, and Sombrerillo Plutonic Massifs in the Garzón region have crystallization ages ranging from 179 to 169 Ma. These rocks are characterized as high-K alkali-calcic or calc-alkaline, magnesian, with 0.66 ≤ Fe# ≤ 0.94, and metaluminous to slightly peraluminous, with 0.67 ≤ ASI ≤ 1.01, exhibiting geochemical signatures. The trace element patterns normalized to MORB reveal pronounced negative anomalies for Nb, P, and Ti, alongside positive anomalies for Pb, Rb, Sr, Y, Zr, and Ba. The REE patterns display strong LREE fractionation over HREEs, with moderate to absent negative Eu anomalies in mafic to intermediate rocks (0.5 ≤ Eu/Eu* ≤ 1.0) and greater significance in felsic rocks (Eu/Eu* up to 0.6). Most granitic rocks display negative εHf(t)-in-zircon values (−7.7 to −1.2), indicating substantial contributions from ancient continental crust. In contrast, the subvolcanic rocks have a mix of positive and negative εHf(t) values (from −7.9 to + 11.5), reflecting significant input from both juvenile mantle and ancient crustal sources (221 Ma ≤ TDM ≤1516 Ma). After 167 Ma, the magmatic activity diminished and ceased in the Garzón region, while it continued to the west in the Central Cordillera until ca. 129–110 Ma, with a gradual increase in contributions from the mantle, as indicated by systematic zircon Hf isotopes, arguably due to changes in the subduction regimes.

En route activity of Chilean Elaenia, a long‐distance migratory bird in South America

En route activity of Chilean Elaenia, a long‐distance migratory bird in South America

A survey to determine the zone of equipoise for the Proximal FEmur Resection or Internal Fixation fOR Metastases (PERFORM) randomized controlled trial.

The objective of this study was to establish a zone of clinical equipoise for the Proximal FEmur Resection or Internal Fixation fOR Metastases (PERFORM) randomized controlled trial, which will compare resection and endoprosthetic reconstruction to internal fixation for skeletal metastases of the proximal femur. A survey was developed, piloted, and distributed to self-declared interested stakeholders in the PERFORM trial. The survey targeted orthopedic oncologists and was designed to assess patient and bone lesion characteristics that drive surgical decision-making in the treatment of skeletal metastases in the proximal femur. An Ethics Waiver was obtained at the lead academic institution and data was collected in the REDCap survey database. Responses were complete from 76 surgeons across North America, South America, Europe, Asia, and Africa. Response rate from self-declared interested stakeholders was 70%, with additional responses collected from a broader international audience. Responses indicate that a study population for which either resection and endoprosthetic reconstruction or internal fixation are acceptable options include (1) life expectancy at least 6months, (2) bone loss of no more than 75% and no less than 25%, and (3) minimal to moderate risk for perioperative complications. Ninety-three percent of respondents indicated that they would be interested in participating in the PERFORM trial. A preliminary zone of equipoise for the PERFORM trial includes patients with 25-75% bone loss, low to moderate risk of operative complications, and life expectancy of at least 6months. Further stakeholder discussions have finalized the PERFORM trial protocol prior to study initiation.

Freshwater salinisation: unravelling causes, adaptive mechanisms, ecological impacts, and management strategies.

Freshwater salinisation is a growing problem worldwide, affecting surface and groundwater resources. Compared with other global environmental issues, freshwater salinisation has been studied extensively in North America, Australia, and Europe but less so in South America, Asia, and Africa. Both the natural and anthropogenic sources can contribute for freshwater salinisation, through the concentration of dissolved salts in water rising above its normal levels. This review provides a comprehensive assessment of the causes of freshwater salinisation, the impacts on freshwater communities and ecosystem functions, the adaptive mechanisms for survival in an increasingly saline environment, and the management strategies available to control freshwater salinisation. Many human activities contribute to freshwater salinisation, including road salt use, agricultural practices, resource extraction, reservoir construction, and climate change. Aquatic organisms have evolved mechanisms to survive in increasingly saline environments, but excessive salinity can lead to mortality and non-lethal effects. Such effects can have cascading impacts on the structure and function of aquatic communities and ecosystem services. Therefore, monitoring programmes and chemical fingerprinting are needed to identify highly salinised areas, determine how various human activities contribute to freshwater salinisation, and implement management strategies. Furthermore, current research on freshwater salinisation has been limited to a few regions of the world. It is essential to expand the research further into exploring the impacts of salinisation on freshwater resources in unexplored geographic areas of the world that are mainly impacted by climate change scenarios.

Mapping the ionosphere with millions of phones.

The ionosphere is a layer of weakly ionized plasma bathed in Earth's geomagnetic field extending about 50-1,500 kilometres above Earth1. The ionospheric total electron content varies in response to Earth's space environment, interfering with Global Satellite Navigation System (GNSS) signals, resulting in one of the largest sources of error for position, navigation and timing services2. Networks of high-quality ground-based GNSS stations provide maps of ionospheric total electron content to correct these errors, but large spatiotemporal gaps in data from these stations mean that these maps may contain errors3. Here we demonstrate that a distributed network of noisy sensors-in the form of millions of Android phones-can fill in many of these gaps and double the measurement coverage, providing an accurate picture of the ionosphere in areas of the world underserved by conventional infrastructure. Using smartphone measurements, we resolve features such as plasma bubbles over India and South America, solar-storm-enhanced density over North America and a mid-latitude ionospheric trough over Europe. We also show that the resulting ionosphere maps can improve location accuracy, which is our primary aim. This work demonstrates the potential of using a large distributed network of smartphones as a powerful scientific instrument for monitoring Earth.

Complementary activity of Trifludimoxazin and Saflufenacil when used in combination for postemergence and residual weed control

Abstract Trifludimoxazin is a new herbicide that inhibits protoporphyrinogen oxidase and is targeted for commercial market introduction in North America, South America, and Asia. It will be available both as a standalone product and in a 1:2 mixture with saflufenacil. The herbicide is intended for use in preplant burndown (PPBD) and preemergence applications in cereal, corn (Zea mays L.), soybean [Glycine max (L.) Merr.], and pulse crops to control a variety of annual broadleaf and grass weed species. Additionally, it is planned to be used in tree crops, oil-palm (Elaeis quineensis Jacq.), and non-crop areas. In this study, we meticulously evaluated the performance and effectiveness of both the standalone herbicide and the innovative mixture concept in combating prevalent weeds commonly encountered in corn and soybean fields. Our findings revealed that both products exhibited exceptional efficacy, significantly reducing the presence of these troublesome weeds. Furthermore, the mixture concept not only demonstrated commendable soil mobility but also showcased impressive residual activity, positioning it as a powerful tool for sustainable weed control. These promising effects are further substantiated by our comprehensive ADME (Adsorption-Distribution-Metabolism-Extraction) studies, which provide insight into the behavior and longevity of the herbicides in the agricultural ecosystem.

Two fancy spines and a collar: a taxonomic review of the myrmecomorphic spider genus Mazax O. Pickard-Cambridge, 1898 (Araneae: Corinnidae: Castianeirinae) in South America

The South American species of the myrmecomorphic spider genus Mazax O. Pickard-Cambridge, 1898 (Castianeirinae, Corinnidae) are revised for the first time, increasing the number of known species from South America from two to six and the number of species in the genus from seven to 11. Here, we reevaluate the identity of Apochinomma acanthaspis Simon, 1896, propose its transfer to Mazax, and consider M. akephaloi Perger & Pett, 2022 as a junior synonym of M. acanthaspis comb. nov. Additional documentation of M. ramirezi Rubio & Danişman, 2014 is provided. The species M. pax Reiskind, 1969 and M. spinosa (Simon, 1898) are recorded from South America for the first time. Three new species are proposed, all based on both sexes: Mazax mokana sp. nov. and M. leonidas sp. nov. from Colombia, and M. tembe sp. nov. from Brazil. Emended diagnoses of the genus and of all six known South American species, as well as a key to males and females for all 11 species in the genus, are provided.

Assessing yellow fever outbreak potential and implications for vaccine strategy.

Yellow fever (YF), a vector-borne viral hemorrhagic fever, is endemic in tropical regions of Africa and South America, with large vaccination programmes being used for control. However, significant outbreaks have occurred in recent years. Data on infection rates and seroprevalence is often sparse, requiring robust mathematical models to estimate the burden of yellow fever. In particular, modelling is required to estimate the risk of outbreaks and inform policy decisions regarding the targeting of vaccination. We present a dynamic, stochastic model of YF transmission which uses environmental covariates to estimate the force of infection due to spillover from the sylvatic (non-human primate) reservoir and the basic reproduction number for human-to-human transmission. We examine the potential for targets identified by the World Health Organization EYE Strategy (50%, 60% or 80% vaccination coverage in 1-60 year olds) to achieve different threshold values for the effective reproduction number. Threshold values are chosen to reflect the potential for seasonal and/or climatic variation in YF transmission even in a scenario where vaccination lowers the median reproduction number below 1. Based on parameter estimates derived from epidemiological data, it is found that the 2022 EYE Strategy target coverage is sufficient to reduce the static averaged annual effective reproduction number R below 1 across most or all regions in Africa depending on the effectiveness of reported vaccinations, but insufficient to reduce it below 0.5 and thereby eliminate outbreaks in areas with high seasonal range. Coverage levels aligned with the 2026 targets are found to significantly decrease the proportion of regions where R is greater than 0.5.