South African Countries Research Articles

Projected impacts of climate change on global irrigation water withdrawals

Investigating processes causing water resource depletion risks is key to understanding past, present, and future excessive irrigation water withdrawal. Quantitative spatiotemporal analysis of the factors driving excessive irrigation water withdrawal is currently inadequate. Although multiple drivers typically contribute to this risk, we studied, for the first time, whether and how Actual Irrigation Water Withdrawals (AIWW) could affect global future water resources projection. Here, we used AIWW datasets from five CMIP6 climate models based on two Shared Socioeconomic Scenarios (SSP370 and 585) and a global hydrological model (H08) to compare the historical (1981–2014) with the future periods: 2041–2070 and 2071–2100. Results show that the temporal AIWW average variations have shown a statistically significant increase during 1981–2014 (p<0.05 and R2 = 0.98) ranging from 101.82 to 136.24 mm yr−1 (mean = 120.5 mm yr−1). Under SSP370 and SSP585, the global spatial AIWW average during 2041–2070 and 2071–2100 are 142.55 and 145.55, and 144.91 and 149.74 mm yr−1, respectively. Under SSP370 and SSP585, the average AIWW changes for 2041–2070 and 2071–2100 are projected to be 96.71, 97.55, 103.52, and 106.98 %, respectively. Under SSP370 and 585, the average global AIWW anomaly changes for 2041–2070 and 2071–2100 are also projected to be −96.86, −106.29, −97.72, and −111.48 %, respectively. Higher AIWW increases are mainly concentrated in India, South China, parts of the United States, parts of Europe, and parts of South African and Latin American countries. Substantiated with population increase, and higher food demand, an increased AIWW will further aggravate globally. Thus, exploring future AIWW changes is a key step forward that requires greater attention in irrigation research interventions helpful to inform societies to reduce future risks of water resource depletion. Adaptation policies targeting the future use of water for irrigation are crucial to lessen water resource depletion risk, suggesting the need for large-scale policy interventions.

Prevalence of group B Streptococcus colonisation in mother–newborn dyads in low-income and middle-income south Asian and African countries: a prospective, observational study

Rectovaginal group B Streptococcus (GBS) colonisation in pregnant individuals at the time of labour is a major risk factor for invasive GBS disease by age 7days (early-onset disease). We aimed to investigate the prevalence of rectovaginal GBS colonisation at the time of labour among pregnant women and vertical transmission to their newborns across selected low-income and middle-income African and south Asian countries. This prospective, observational study was undertaken at 11maternity and obstetric care facilities based in Ethiopia, Kenya, Mozambique, Nigeria, Mali, South Africa, Bangladesh, India, and Bhutan. HIV-negative pregnant women aged 18-45years who were in the early stages of labour and at least 37weeks' gestation were eligible for inclusion. Lower vaginal and rectal swabs and urine were collected from the women, and swabs of the umbilicus, outer ear, axillary fold, rectum, and throat were obtained from their newborns, for GBS culture. Standardised sampling and culture using direct plating and selective media broth for detection of GBS colonisation was undertaken at the sites. Serotyping of GBS isolates was done in South Africa. The primary outcome was the prevalence of rectovaginal GBS among pregnant women, analysed in participants with available data. This study is registered with the South African National Clinical Trials Register, number DOH-27-0418-4989. 6922pregnant women were enrolled from Jan 10, 2016, to Dec 11, 2018, of whom 6514 (94·1%; 759-892per country) were included in the analysis; data from Bhutan were not included in the study due to issues with specimen collection and processing. Overall, the prevalence of maternal GBS colonisation was 24·1% (95% CI 23·1-25·2; 1572of 6514); it was highest in Mali (41·1% [37·7-44·6]; 314of 764) and lowest in Ethiopia (11·6% [9·5-14·1]; 88of 759). Theoverall rate of vertical transmission of GBS from women with rectovaginal GBS colonisation was 72·3% (70·0-74·4; 1132of 1566); it was highest in Mozambique (79·2% [73·3-84·2]; 168of 212) and lowest in Bangladesh (55·8%, 47·5-63·8; 77of 138). The five most common GBS colonising serotypes were Ia (37·3% [34·9-39·7]; 586of 1572), V(28·5% [26·3-30·8]; 448of 1572), III (25·1% [23·0-27·3]; 394of 1572), II (9·2% [7·8-10·7]; 144of 1572), and Ib(6·5% [5·4-7·8]; 102of 1572). There was geographical variability in serotype proportion distribution; serotype VIIwas the third most common serotype in India (8·6% [5·3-13·7]; 15of 174) and serotype VI was mainly identified in Bangladesh (5·8% [3·0-11·0]; eight of 138) and India (5·7% [3·2-10·3]; ten of 174). Our study reported a high prevalence of GBS colonisation in most settings, with some geographical variability even within African countries. Our findings suggest that serotypes not included in current multivalent capsular-polysaccharide GBS vaccines prevail in some regions, so vaccine efficacy and post-licensure effectiveness studies should assess the effect of vaccination on maternal GBS colonisation given the potential for replacement by non-vaccine serotypes. Bill & Melinda Gates Foundation.

Seasonal Maize yield forecasting in South and East African Countries using hybrid Earth observation models

Climate change still adversely affects agriculture in the sub-Saharan Africa. There is need to strengthen early action to bolster livelihoods and food security. Most governments use pre- and post-harvest field surveys to capture statistics for National Food Balance Sheets (NFBS) key in food policy and economic planning. These surveys, though accurate, are costly, time consuming, and may not offer rapid yield estimates to support governments, emergency organizations, and related stakeholders to take advanced strategic decisions in the face of climate change. To help governments in Kenya (KEN), Zambia (ZMB), and Malawi (MWI) adopt digitally advanced maize yield forecasts, we developed a hybrid model based on the Regional Hydrologic Extremes Assessment System (RHEAS) and machine learning. The framework is set-up to use weather data (precipitation, temperature, and wind), simulations from RHEAS model (soil total moisture, soil temperature, solar radiation, surface temperature, net transpiration from vegetation, net evapotranspiration, and root zone soil moisture), simulations from DSSAT (leaf area index and water stress), and MODIS vegetation indices. Random Forest (RF) machine learning model emerged as the best hybrid setup for unit maize yield forecasts per administrative boundary scoring the lowest unbiased Root Mean Square Error (RMSE) of 0.16 MT/ha, 0.18 MT/ha, and 0.20 MT/ha in Malawi's Karonga district, Kenya's Homa Bay county, and Zambia's Senanga district respectively. According to relative RMSE, RF outperformed other hybrid models attaining the lowest score in all countries (ZMB: 25.96%, MWI: 28.97%, and KEN: 27.54%) followed by support vector machines (ZMB: 26.92%, MWI: 31.14%, and KEN: 29.50%), and linear regression (ZMB: 29.44%, MWI: 31.76%, and KEN: 47.00%). Lastly, the integration of VI and RHEAS information using hybrid models improved yield prediction. This information is useful for NFBS bulletins forecasts, design and certification of maize insurance contracts, and estimation of loss and damage in the advent of climate justice.

Performance Evaluation of Different Finger Millet (Eleusine coracana L. Gaertn.) Cultivars for Growth, Productivity and Nutrient Quality of Grains Under Hot and Subhumid Region of Odisha

Millets are cultivated world-wide and are more prominent in South Asian and African countries. Among different millets, finger millets hold a significant position in terms of area and productivity. Due to negligence in various cultivation practices and improper selection of genotypes, most farmers fail to achieve optimum yields. In this scenario, the choice of a suitable cultivar is essential. Considering the above, an experiment was conducted at Post Graduate Research Farm of Centurion University of Technology and Management, Odisha, to evaluate suitable cultivars of finger millet. The study consisted of eight treatments comprising of V1: VL Mandua, V2: Hima, V3: Indravathi, V4: Vegavathi, V5: Champavathi, V6: Suvarnamukhi, V7: Bharathi, V8: Sri Chaitanya. The treatments were replicated thrice and the randomized block design was implemented. The results revealed that the highest plant height (158 cm) was observed with the cultivar Bharathi. Indravathi recorded the highest dry matter accumulation at harvest (776 g m-2), leaf area index at 50 DAT (3.56) and number of tillers at 50 DAT (66). However, the highest effective tillers per m2 (2.3) were recorded with the cultivar Sri Chaitanya, and the highest number of grains per ear head and weight per ear head were registered in the Bharathi variety. Further, the highest numbers of fingers per ear head (8.4), 1000 grain weight (2.82g), weight of grains hill-1 (6.72g) and length of finger (7.7cm) were recorded in the variety Indravathi. The cultivar Indravathi recorded the highest grain (2315 kg ha-1), stover (5372 kg ha-1) and biological yield (7687 kg ha-1) and Sri Chaitanya followed it. The study concludes that Indravathi and Sri Chaitanya can be considered short-duration and Hima as long duration cultivar for obtaining higher yield during Kharif season (July to September) under the hot and subhumid regions of Odisha.

Transmission of viable Haemophilus ducreyi by Musca domestica.

Haemophilus ducreyi was historically known as the causative agent of chancroid, a sexually-transmitted disease causing painful genital ulcers endemic in many low/middle-income nations. In recent years the species has been implicated as the causative agent of nongenital cutaneous ulcers affecting children of the South Pacific Islands and West African countries. Much is still unknown about the mechanism of H. ducreyi transmission in these areas, and recent studies have identified local insect species, namely flies, as potential transmission vectors. H. ducreyi DNA has been detected on the surface and in homogenates of fly species sampled from Lihir Island, Papua New Guinea. The current study develops a model system using Musca domestica, the common house fly, as a model organism to demonstrate proof of concept that flies are a potential vector for the transmission of viable H. ducreyi. Utilizing a green fluorescent protein (GFP)-tagged strain of H. ducreyi and three separate exposure methods, we detected the transmission of viable H. ducreyi by 86.11% ± 22.53% of flies sampled. Additionally, the duration of H. ducreyi viability was found to be directly related to the bacterial concentration, and transmission of H. ducreyi was largely undetectable within one hour of initial exposure. Push testing, Gram staining, and PCR were used to confirm the identity and presence of GFP colonies as H. ducreyi. This study confirms that flies are capable of mechanically transmitting viable H. ducreyi, illuminating the importance of investigating insects as vectors of cutaneous ulcerative diseases.

Unveiling the Path to Healthy Habits: The Effect of School-Led Total Sanitation Intervention on Sanitation and Hygiene Knowledge and Practices Among School-Going Children (Grade 4–7) in Baringo County, Kenya

Background: Poor hygiene and sanitation knowledge and practices pose serious health risks to vulnerable populations, such as school-going children. Kenya is among the 26 countries worldwide that account for 90% of open defecation. School-led total sanitation (SLTS) is a novel intervention that has been successfully implemented in South African countries to improve sanitation and hygiene outcomes among school-going children. Despite the intervention’s success elsewhere, it has not been implemented in Kenya. The main aim of this study was to assess SLTS’ effectiveness in improving sanitation and hygiene knowledge and practices among school-going children in Baringo County. Methods: A quasi-experimental study was conducted involving 434 pupils divided into intervention and control groups across three schools in each study group. A six-month intervention included triggering, forming health clubs, training sessions, and distributing information, education, and information materials. Thereafter, an evaluation was performed 3 months post-intervention. The data were analyzed using SPSS V18. The Chi-square test was used to compare knowledge and practices in both groups, while the difference in differences (DID) method assessed intervention effectiveness. Results: Compared to the control group (15.2%), children in the intervention group (63.2%) showed significantly high knowledge levels (χ2=104.67, df=1, P&lt;0.0001). There was a 52.3% mean increase in knowledge among children in the intervention group. A more considerable number of pupils (85.6%) in the intervention schools washed their hands with soap compared to 65.5% (χ 2=23.57, df=1, P&lt;0.0001) in the control group, demonstrating an increase of 19.6%. In the intervention group, there was a significantly lower proportion of pupils who practiced open defecation at home (16.3%) compared to 35.4% in the control group (χ 2=25.0, df=1, P&lt;0.0001). Conclusion: The SLTS intervention led to an increase in knowledge on sanitation and hygiene but a reduction in open defecation at home among school-going children. These findings revealed that SLTS is an effective approach that can be adopted by regional governments, national governments, and other stakeholders as an additional intervention to address the problem of poor hygiene and sanitation in Kenya.

The Effect of Digital Mental Health Literacy Interventions on Mental Health: Systematic Review and Meta-Analysis.

Accelerated by technological advancements and the recent global pandemic, there is burgeoning interest in digital mental health literacy (DMHL) interventions that can positively affect mental health. However, existing work remains inconclusive regarding the effectiveness of DMHL interventions. This systematic review and meta-analysis investigated the components and modes of DMHL interventions, their moderating factors, and their long-term impacts on mental health literacy and mental health. We used a random-effects model to conduct meta-analyses and meta-regressions on moderating effects of DMHL interventions on mental health. Using 144 interventions with 206 effect sizes, we found a moderate effect of DMHL interventions in enhancing distal mental health outcomes (standardized mean difference=0.42, 95% CI -0.10 to 0.73; P<.001) and a large effect in increasing proximal mental health literacy outcomes (standardized mean difference=0.65, 95% CI 0.59-0.74; P<.001). Uptake of DMHL interventions was comparable with that of control conditions, and uptake of DMHL interventions did not moderate the effects on both proximal mental health literacy outcomes and distal mental health outcomes. DMHL interventions were as effective as face-to-face interventions and did not differ by platform type or dosage. DMHL plus interventions (DMHL psychoeducation coupled with other active treatment) produced large effects in bolstering mental health, were more effective than DMHL only interventions (self-help DMHL psychoeducation), and were comparable with non-DMHL interventions (treatment as usual). DMHL interventions demonstrated positive effects on mental health that were sustained over follow-up assessments and were most effective in enhancing the mental health of emerging and older adults. For theory building, our review and meta-analysis found that DMHL interventions are as effective as face-to-face interventions. DMHL interventions confer optimal effects on mental health when DMHL psychoeducation is combined with informal, nonprofessional active treatment components such as skills training and peer support, which demonstrate comparable effectiveness with that of treatment as usual (client-professional interactions and therapies). These effects, which did not differ by platform type or dosage, were sustained over time. Additionally, most DMHL interventions are found in Western cultural contexts, especially in high-income countries (Global North) such as Australia, the United States, and the United Kingdom, and limited research is conducted in low-income countries in Asia and in South American and African countries. Most of the DMHL studies did not report information on the racial or ethnic makeup of the samples. Future work on DMHL interventions that target racial or ethnic minority groups, particularly the design, adoption, and evaluation of the effects of culturally adaptive DMHL interventions on uptake and mental health functioning, is needed. Such evidence can drive the adoption and implementation of DMHL interventions at scale, which represents a key foundation for practice-changing impact in the provision of mental health resources for individuals and the community. PROSPERO International Prospective Register of Systematic Reviews CRD42023363995; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023363995.

Macroeconomic Determinants of Tax Revenues of South African Countries

This research explores the macroeconomic elements that impact tax income in countries in South Africa. The study considers five countries: Namibia, Botswana, Zimbabwe, South Africa, and Zambia. Its primary objective is to identify key factors influencing tax revenue in these nations and examine their economic impact. Employing multivariate regression analysis, the research evaluates the impact of various macroeconomic indicators, including economic growth, inflation, foreign direct investment, and trade openness on tax revenues, using data from 1990 to 2021. Results indicate that economic growth and trade openness positively influence tax revenue, while inflation adversely affects it. The impact of foreign direct investment on tax revenue varies by country. These findings carry significant policy implications for South African nations, highlighting the importance of focusing on trade liberalization and economic growth to boost tax revenues, while also controlling inflation.

Addressing Poverty through Social Entrepreneurship for Sustainable Development: A Comprehensive Bibliometric Analysis

The increasing social and environmental challenges, particularly poverty, have brought social entrepreneurship, a highly researched domain, to the attention of academicians. It has emerged as a critical issue in the context of economic development and societal well-being. The current study presents a comprehensive bibliometric analysis in the field of social entrepreneurship and poverty alleviation to explain the current state, geographical performance, and future research agenda. Utilizing VOS viewer (version 1.6.20) and R Studio software (version 4.3.2), 461 final articles were examined and extracted from the Web of Science database, covering the period from 1998 to 2022. The findings reveal a significant increase in research activity in this field since 2009, indicating a growing demand for it as a solution to social challenges. Notably, the years 2021–2022 witnessed a remarkable 55% surge in research output. The Sustainability Journal ranks first as the most productive source, followed by the Journal of Cleaner Production. The most prolific authors are Nina Kolleck from Germany, David Littlewood, and Diane Holt from the UK. Additionally, this study assesses the geographic distribution of research contributions, highlighting regions with relatively lower research performance, such as South Asian and African countries. Leading in this domain are the UK, Spain, the USA, and European institutions. Co-citation patterns reveal four thematic clusters: (1) dynamics of social entrepreneurship; (2) sustainable entrepreneurial ecosystem; (3) social entrepreneurship for social innovation; and (4) integrated sustainable entrepreneurship, shedding light on critical aspects and the intellectual structure of this domain. Finally, keyword co-occurrence analysis identifies emerging research areas, e.g., entrepreneurial development, the role of higher education, enterprise collaboration, inclusive growth, and socio-economic empowerment. This research provides valuable insights for policymakers, researchers, and practitioners committed to achieving sustainable social change.

Carbon reduction policies based on the example of South America and Africa

This article examines the political economy of decarbonization in South American and African countries from 2000 to 2021-2022, which have already reached national zero transition. These countries include Suriname, Panama, and Guyana, Comoros. An analytical approach is used, including a rich interdisciplinary systematic literature review and thematic analysis. For each country, the driving forces and political motivation for achieving zero emissions are explored, including the timing, obstacles and benefits of decarbonization, as well as its impact on equality and equity. The main goal of the study is to expand the database on low—carbon transitions beyond the often studied Western, developed, rich and democratic countries (WEIRD) and provide new empirical data on energy policy strategies in the real world. All countries apply similar approaches related to land use, renewable energy sources and waste management. Common obstacles include vulnerability to extreme climate events such as natural disasters and ecosystem degradation. Despite these challenges, achieving zero emissions has a positive impact on marginalized communities, ensuring a more equitable distribution of climate benefits, mitigating negative health effects and reducing social inequality, especially in low-income areas.

Do black women's lives matter? A study of the hidden impact of the barriers to access maternal healthcare for migrant women in South Africa.

Studies on the barriers migrant women face when trying to access healthcare services in South Africa have emphasized economic factors, fear of deportation, lack of documentation, language barriers, xenophobia, and discrimination in society and in healthcare institutions as factors explaining migrants' reluctance to seek healthcare. Our study aims to visualize some of the outcome effects of these barriers by analyzing data on maternal death and comparing the local population and black African migrant women from the South African Development Countries (SADC) living in South Africa. The heightened maternal mortality of black migrant women in South Africa can be associated with the hidden costs of barriers migrants face, including xenophobic attitudes experienced at public healthcare institutions. Our analysis is based on data on reported causes of death (COD) from the South African Department of Home Affairs (DHA). Statistics South Africa (Stats SA) processed the data further and coded the cause of death (COD) according to the WHO classification of disease, ICD10. The dataset is available on the StatsSA website (http://nesstar.statssa.gov.za:8282/webview/) for research and statistical purposes. The entire dataset consists of over 10 million records and about 50 variables of registered deaths that occurred in the country between 1997 and 2018. For our analysis, we have used data from 2002 to 2015, the years for which information on citizenship is reliably included on the death certificate. Corresponding benchmark data, in which nationality is recorded, exists only for a 10% sample from the population and housing census of 2011. Mid-year population estimates (MYPE) also exist but are not disaggregated by nationality. For this reason, certain estimates of death proportions by nationality will be relative and will not correspond to crude death rates. The total number of female deaths recorded from the years 2002 to 2015 in the country was 3740.761. Of these, 99.09% (n = 3,707,003) were deaths of South Africans and 0.91% (n = 33,758) were deaths of SADC women citizens. For maternal mortality, we considered the total number of deaths recorded for women between the ages of 15 and 49 years of age and were 1,530,495 deaths. Of these, deaths due to pregnancy-related causes contributed to approximately 1% of deaths. South African women contributed to 17,228 maternal deaths and SADC women to 467 maternal deaths during the period under study. The odds ratio for this comparison was 2.02. In other words, our findings show the odds of a black migrant woman from a SADC country dying of a maternal death were more than twice that of a South African woman. This result is statistically significant as this odds ratio, 2.02, falls within the 95% confidence interval (1.82-2.22). The study is the first to examine and compare maternal death among two groups of women, women from SADC countries and South Africa, based on Stats SA data available for the years 2002-2015. This analysis allows for a better understanding of the differential impact that social determinants of health have on mortality among black migrant women in South Africa and considers access to healthcare as a determinant of health. As we examined maternal death, we inferred that the heightened mortality among black migrant women in South Africa was associated with various determinants of health, such as xenophobic attitudes of healthcare workers toward foreigners during the study period. The negative attitudes of healthcare workers toward migrants have been reported in the literature and the media. Yet, until now, its long-term impact on the health of the foreign population has not been gaged. While a direct association between the heightened death of migrant populations and xenophobia cannot be established in this study, we hope to offer evidence that supports the need to focus on the heightened vulnerability of black migrant women in South Africa. As we argued here, the heightened maternal mortality among migrant women can be considered hidden barriers in which health inequality and the pervasive effects of xenophobia perpetuate the health disparity of SADC migrants in South Africa.

Cohort profile: the Pregnancy Risk Infant Surveillance and Measurement Alliance (PRISMA) – Pakistan

PurposePakistan has disproportionately high maternal and neonatal morbidity and mortality. There is a lack of detailed, population-representative data to provide evidence for risk factors, morbidities and mortality among pregnant women...

Seroprevalence of Human Immunodeficiency Virus, Hepatitis C Virus, and Hepatitis B Virus Among Blood Donors in Sidi Bel Abbes, West Algeria.

Introduction Blood transfusions can transmit various viruses. Among them, the most common are hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). These viruses can cause fatal and life-threatening diseases. Worldwide, many people are infected with these viruses. Blood safety has made majorprogress in recent years. Yet, blood-borne viruses continue to be a major concern for patients, physicians, and policymakers. The aim of this study was to assessthe prevalence of HIV, HBV, and HCV in blood donors. Methods A cross-sectional study was performed to assess HIV, HBV, and HCV seropositivity in blood donors. This research was carried out at the blood bank of Sidi Bel Abbes University Hospital. This was a retrospective study based on records of blood donors. All data of 10,386 donors were analyzed from January 2015 to December 2015. Biological screening was performed by enzyme-linked immunosorbent assay (ELISA) using antibodies and/or antigens. The combined HCV and HIV antigen and antibody ELISA test was utilized. To confirm the results, the blood bank and the virology laboratory used the same technique in duplicate. Results The overall seroprevalence of blood-borne viral infections (HIV, HBV, and HCV) in blood donors was 0.8%. The prevalence of HIV was found to be 0.1%, while the prevalence of HBV and HCV was 0.4%. Coinfection was rare with only one case of HBV with HIV.There was a significant difference in seroprevalence rates among blood donors compared to the general population. Significant variations were observed between the prevalence of this study and those conducted in West, East, Central, and South African countries but not with those of neighboringNorth African countries. The study found no association between seropositivity in blood donors and factors like age, gender, donor status, type of donation, or site. Besides, HIV, HBV, or HCV prevalence was not influenced by ABO and Rhesus blood group. Conclusion The study showed that blood donors in Algeria have a lower prevalence of blood-borne viral infections than the general population. The seropositivity rate of viral markers was similar throughout North African countries. This rate remained low compared to other African countries. Residual risk of infection persists. There is a need to increase blood safety for recipients. This report is the first comprehensive overview of blood-borne viruses among Algerian blood donors. There is a need for further nationwide studies to get a whole picture of the situation.

Global long-term trends and spatial cluster analysis of pancreatic cancer incidence and mortality over a 30-year period using the global burden of disease study 2019 data.

Pancreatic cancer (PC) is one of the most fatal malignancies, and its incidence and mortality rates are growing annually throughout the world. In this research, we aimed to investigate the time trends and identify the spatial clusters of incidence and mortality on a global scale over the last 30 years, using the Global Burden of Disease (GBD) study 2019 data. Age-standardized incidence and mortality data due to PC were extracted from the GBD study, which was carried out from 1990 to 2019. A Joinpoint regression analysis was utilized to examine trends in the incidence and mortality of PC over the past three decades. As such, spatial analyses were undertaken to detect the spatial distribution and clustering of the metrics globally. It was observed that both the incidence and mortality rates were higher in males than in females worldwide. The global mortality and incidence rates significantly increased by 0.8% per year over the time of follow-up period (p<0.05). By spatial cluster analysis for mortality, European and North African countries, as well as Greenland were explored as hot spots; while South African and Southeast Asian countries were explored as cold spots. Regarding incidence, hot spots were found in European countries, Southern America, and Greenland; whilst cold spots were determined in Southern Africa and Madagascar. Collectively, the temporal trends disclosed a gradual rise in PC incidence and mortality rates over the period 1990-2019, reflecting the global health concern. We further found geographical variations in the patterns and identified high- and low-risk areas for incidence and mortality. These findings facilitate the design and implementation of more resource-efficient and geographically targeted treatments. Given the results of the current study, a practical approach to minimizing the future PC burden involves planned population-wide interventions, as well as primary prevention through healthier lifestyles.

Hydrogen as a Renewable Energy Carrier in a Hybrid Configuration of Distributed Energy Systems: Bibliometric Mapping of Current Knowledge and Strategies

Storing energy in hydrogen deposits balances the operation of energy systems and is an effective tool in the process of energy transformation towards achieving Sustainable Development Goals. To assess the validity of its use as an alternative renewable energy carrier in dispersed energy systems of hybrid configuration, a comprehensive review of scientific literature was conducted in this study, based on bibliometric analysis. The bibliographic database used in the study was the international Web of Science database. This review contributes to a better understanding of the characteristics of the selected research area. The evolution of research trends implemented in the design of energy systems associated with hydrogen technologies is revealed, clearly indicating that it is a developing field. In recent years, there has been an increase in the number of publications, although the territorial range of research (mainly simulation) conducted in the domain does not include areas with the most favourable infrastructural conditions. The analysis reveals weak cooperation between South American, African, East Asian, and Oceanic countries. In the light of earlier, thematically similar literature reviews, several research gaps are also identified and proposals for future research are presented. They concern, in particular, the parallel implementation and optimization of the operation of hydrogen (HRES—Hybrid Renewable Energy System and HESS—Hybrid Energy Storage System) solutions in terms of economics, ecology, lifespan, and work efficiency, as well as their feasibility analysis. With the support of other researchers and those involved in the subject matter, this review may contribute to the further development of hybrid hydrogen systems in terms of increasing competitiveness and promoting the implementation of these technologies.

Educational achievements and export earnings: a comparison between leader and follower countries

PurposeThis study examines whether education in developing countries directly impacts their foreign income from the top export sector.Design/methodology/approachAs most developing countries follow developed nations to shape their development, this study assumes developing countries as education-follower and developed countries as education-leader countries. Considering selected countries from the South Asian Regional Cooperation (SAARC) and African countries as follower countries and Group of Seven (G7) as leader countries, this study employs Dumitrescu-Hurlin Granger non-causality tests.FindingsThis study finds that education-follower countries' achievements do not directly impact foreign earnings from their leading export sectors. However, findings also confirm that leader countries have a bidirectional causal relationship between tertiary education and earnings from high technology exports.Originality/valueTo the best of the authors' knowledge, this is the first study urging research-intensive education with comparative advantages in international trade. Using educational attainment on export earnings from the leading sector, findings support dependency theory in education is still existed.

Ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological profile of Morus alba L.: A comprehensive review

Morus alba L. is a member of family Moraceae that have been traditionally used to cure various ailments in many Asian, South African and European countries. The plant has significant economic value due to its sweet and nutritious fruits which are used in various culinary applications. In addition, the leaves of this plant serve as the primary food source for silkworms, making it a crucial component of the global silk industry. Furthermore, the plant has a long history of use in traditional medicine, and its leaves, bark, and fruit have been utilized for their various therapeutic properties. Morus alba has been extensively studied for its phytochemistry, ethnopharmacology and toxicological profile, with many studies showing promising results. However, despite the growing interest in this plant, there are very few extensive reviews on this topic. The current review provides a comprehensive summary of the distribution, traditional and ethnomedicinal uses, phytochemistry, pharmacological activities and active chemical constituents of M. alba. This study includes distribution and ethnomedicinal use of this plant in different regions of India, explored the phytochemicals, their structure and pharmacological significance. Furthermore, a comparative analysis and investigation revealed the potential of this plant for treating cancer, diabetes, inflammation, hepatoprotection, immunomodulation, antimicrobial properties, and potential for fighting coronavirus. Though, detailed studies are required on the clinical use of M. alba against human diseases. Additionally, the present study revealed that a thorough toxicological investigation must be carried out to ensure its safe and effective use as a health-promoting medicinal plant.

Burden of Neural Tube Defects and Their Associated Factors in Africa: A Systematic Review and Meta-Analysis.

Neural tube defects are a type of congenital anomaly caused by an abnormality in the development of the brain and spinal cord during embryogenesis. They cause high rates of mortality, morbidity, and lifelong disability. There are several studies carried out worldwide reporting different findings on the burden and associated factors. The aim of this study is to carry out a systematic review and meta-analysis of the burden of neural tube defects and their associated factors in Africa. A total of 58 eligible articles were identified systematically using databases such as PubMed, Embase, African Journal Online Library, ProQuest, Cochrane, Google Scopus, Google Scholar, and Grey literature. Extracted data were analyzed using STATA 16.0 statistical software. The heterogeneity of studies was determined using the Cochrane Q test statistic and I2 test statistics with forest plots. A random effects model was used to examine the pooled burden of neural tube defects, subgroups of the region, subtypes of NTDs, sensitivity analysis, and publication bias. The association between NTDs and associated factors was studied using a fixed-effect model. Fifty-eight studies with a total of 7,150,654 participants in 16 African countries revealed that the pooled burden of neural tube defects was 32.95 per 10,000 births (95% CI: 29.77-36.13). The Eastern African region had the highest burden in the subgroup analysis, with 111.13 per 10,000 births (95% CI: 91.85-130.42). South African countries had the lowest burden, at 11.43 per 10,000 births (95% CI: 7.51-15.34). In subtype analysis, spina bifida had the highest pooled burden at 17.01 per 10,000 births (95 percent CI: 15.00-19.00), while encephalocele had the lowest at 1.66 per 10,000 births (95% CI: 1.12-2.20). Maternal folic acid supplementation (AOR: 0.38; 95% CI: 0.16-0.94), alcohol consumption (AOR: 2.54; 95% CI: 1.08-5.96), maternal age (AOR: 3.54; 95% CI: 1.67-7.47), pesticide exposure (AOR: 2.69; 95% CI: 1.62-4.46), X-ray radiation (AOR: 2.67; 95% CI: 1.05-6.78), and history of stillbirth (AOR: 3.18; 95% CI: 1.11-9.12) were significantly associated with NTDs. The pooled burden of NTDs in Africa was found to be high. Maternal age, alcohol consumption, pesticide and X-ray radiation exposure, history of stillbirth, and folic acid supplementation were significantly associated with NTDs.

Renewable and nonrenewable energy consumption, economic growth, and CO2 emissions in Eastern and South African countries: the role of informality.

This study investigates the role of informality in the relationship among renewable and nonrenewable energy consumption, economic growth, and CO2 emissions in a panel of 19 Eastern and South African countries. The empirical strategy exploits the panel generalized method of moments, panel fixed effects models using the Driscoll-Kraay standard errors, panel method of moments quantile regressions, and the Dumitrescu-Hurlin bootstrap panel Granger causality analysis. The results are fourfold. First, nonrenewable energy consumption is positively associated with CO2 emissions, while renewable energy consumption is not. Second, there is a nonlinear ∩ -shaped relationship between economic growth and CO2 emissions, consistent with the environmental Kuznets curve (EKC) hypothesis. Third, the results show a nonlinear ∪ -shaped relationship between informality and CO2 emissions, suggesting that higher informality is associated with lower CO2 emissions up to a certain critical point beyond which further increases in informality precipitate higher CO2 emissions. Fourth, the results show unidirectional causality from CO2 emissions to renewable energy, from CO2 emissions to nonrenewable energy, from informality to CO2 emissions, and feedback causality between GDP growth and CO2 emissions.

Almost nothing is known about the tiger shark in South Atlantic waters.

The tiger shark (Galeocerdo cuvier) has been relatively well assessed concerning biology and ecology aspects in both Atlantic and Pacific North America and in Caribbean waters. The amount of data in these regions has led to the species protection under capture quotas and with the creation of sanctuaries. The reality in developing countries, however, is the exact opposite, with scarce information on the species in the southern hemisphere, namely South American and African waters. In these regions, protection measures are insufficient, and studies on tiger shark biology and ecology are scarce, significantly hindering conservation and management efforts. Thus, the aim of this study was to compile scientific literature on the tiger shark in the South Atlantic and discuss the impact of these data (or lack thereof) distributed within a total of ten research categories for guiding management plans. In total, 41 scientific publications on different G. cuvier biology and ecology aspects were obtained. The most studied topics were Feeding Ecology (n = 12), followed by Human Interactions (n = 8), and Movements and Migration (n = 7). Northeastern Brazil (Southwest Atlantic) was the most researched area, probably due to the higher coastal abundance of tiger sharks in this area, alongside a high number of recorded attacks, justifying funding for studies in the region. No studies carried out in other South American or African countries were found. It is important to mention that even though some research topics are relatively well covered, a severe knowledge gap is noted for risk assessments and fisheries management, with a proposition for the implementation of sanctuaries noted. This is, however, particularly worrisome, as the South Atlantic is mostly unexplored in this regard for tiger sharks. It is also important to note how different the attention given to this species is in the North Atlantic when compared to the South region. Lastly, we highlight that the existence of sub-populations, the lack of migratory corridors geographically connecting distinct areas used by the species, and the lack of fisheries statistics on tiger shark landings, all increase the vulnerability of this species in the South Atlantic.