This article explores the potential of the Blue Economy and its application for sustainable development, focusing on the Mtwara region in Tanzania. It begins by examining the definitions, drivers, and future trends of the Blue Economy. The study is guided by three primary objectives: assessing current coastal resources and ecosystems in Mtwara, evaluating the effectiveness of existing Integrated Coastal Management (ICM) initiatives, and analyzing policy and governance frameworks related to coastal resource management in Tanzania. The research methodology includes a review of governance frameworks across major Blue Economy sectors and semi-structured interviews to uncover insights, challenges, and policy implications. Guided by the Social-Ecological Systems (SES) framework, the article emphasizes the interconnectedness of human activities and natural processes, essential for sustainable development. The article is structured into sections: background on the Blue Economy, foundational perspectives, discussion, and conclusion.