Smoking Cessation Programs Research Articles

Smokers have increased risk of soft-tissue complications following primary elective TKA

IntroductionSmoking has been associated with numerous adverse outcomes following surgical procedures. The purpose of this study was to investigate, whether smoking status at time of surgery influences the outcome of primary TKA.Materials and methodsSix hundred and eighty-one patients who underwent primary TKA between 2003 and 2006 were included in the study. Smoking status was defined as current, former, and never smoker. Complications leading to revisions were assessed until 17 years of follow-up. Functional outcome was evaluated using clinical scores: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Visual Analogue Scale (VAS) for pain, Short Form-12 Physical and Mental Component Summaries (SF-12PCS/MCS), and Knee Society Function and Knee Score (KSFS and KSKS).ResultsAt a mean follow-up of 95 months (± 47 months), 124 complications led to revision surgery. Soft-tissue complications (OR, 2.35 [95% CI 1.08–5.11]; p = 0.032), hematoma formation (OR, 5.37 [95% CI 1.01–28.49]; p = 0.048), and restricted movement (OR, 3.51 [95% CI 1.25–9.84]; p = 0.017) were more likely to occur in current smokers than never smokers. Current smokers were more likely to score higher at KSFS (p < 0.001) and SF-12PCS (p = 0.0197) compared to never smokers. For overall revision, differences were noted.ConclusionCurrent smoking increases risk of soft-tissue complications and revision after primary TKA, especially due to hematoma and restricted movement. Smoking cessation programs could reduce the risk of revision surgery.

Respiratory health and its determinants among Nunavimmiut: results from the Qanuilirpitaa? 2017 Nunavik Health Survey

ObjectivesRespiratory diseases are the leading cause of hospitalization in Nunavik (northern Québec, Canada) and contribute to disparities in life expectancy with the rest of Canada. As part of Qanuilirpitaa? 2017, a cross-sectional population-based health survey, we sought to describe the prevalence of respiratory health indicators, including the first estimate of airway obstruction based on spirometry in an Inuit population, and explore their associated characteristics.MethodsWe analyzed data from 1296 participants aged 16 years and older, using multivariate logistic regression to assess characteristics associated with spirometry-determined airway obstruction and self-reported respiratory symptoms, i.e., wheezing in the last year and chronic cough during at least 3 months.ResultsIn this relatively young population (83% aged 16 to 54), the prevalences of wheezing, chronic cough, and airway obstruction were, respectively, 27% (95% CI 24–30), 21% (18–23), and 17% (14–20). These estimates are prone to biases due to the relatively low participation rate (about 37%). The most consistent associations were with smoking (≥ 15 pack-years; odds ratio [OR] 3.13, 3.39, and 2.86 for the three indicators, respectively) and food security (OR 0.55 with wheezing and OR 0.26 with chronic cough), as defined in the Household Food Security Survey Module. Wheezing was also associated with allergic sensitization to dogs (2.60) and obesity (2.18). Chronic cough was associated with respiratory infections during childhood (2.12), housing in need of major repairs (1.72), and housing crowding (1.50), and was negatively associated with participation to traditional activities (0.62) and going on the land (0.64). Airway obstruction was associated with being underweight (3.84) and post-secondary education (0.40). Among young adults and women, wheezing was also associated with any inhalation of solvents for recreational purposes during their lifetime (2.62 and 1.56, respectively), while airway obstruction was associated with regular marijuana use (2.22 and 1.84, respectively).ConclusionSmoking and food insecurity are both highly prevalent and strongly associated with respiratory symptoms in Nunavik. Together with essential smoking prevention and cessation programs, our findings suggest that solving food security and housing crises, improving socioeconomic conditions, and promoting traditional lifestyle may improve respiratory health in Nunavik.

Efficacy of Combined Relaxed Deep-Breathing with Chest Mobilization Exercise and Vernonia cinerea-Hard Candy on Smoking Cessation and Oxidative Stress in Active Teenage Smokers

Background: Smoking cessation is very important worldwide. Chronic smoking can induce oxidative stress and inflammatory status and induce dangerous diseases such as hypertension and lung cancer. Standardized counseling is an important process in a routine program for smoking cessation. Withdrawal symptoms from smoking cessation are a significant barrier to a successful result, and they can be relieved by relaxed deep-breathing exercise. At present, the Thai herb, Vernonia cinerea (VC), has been claimed to reduce cigarette smoking because of its antioxidant compounds and nicotine that are modified and used as lozenges, gum, and hard candy. However, its efficacy in smoking cessation has not been confirmed. Furthermore, the efficacy of relaxed deep-breathing (rDB) during the chest mobilization exercise (CME) with VC hard candy on smoking cessation and oxidative stress is unclear. Objective: This study aimed to evaluate the combined effects of rDB/CME and VC-hard candy on smoking cessation and oxidative stress status in active teenage smokers. Methods: Hard candy with honey and VC powder from whole mixed parts of the stem, flowers and leaves was developed industrially under the spray dry technique. Thirty active smokers were randomized into three groups; product group (rDB/CME+ product) (aged 25.0 ± 3.0 years, n = 10), placebo group (rDB/CME + placebo) (aged 26.9 ± 3.7 years, n = 10), and a control group with no product or placebo administered (aged 25.6 ± 2.7 years, n=10). All of the groups received consultation on specific smoking cessation and two weeks of strict observation, which was followed up for 8 weeks. The 7-day point prevalence abstinence rates (7-day PAR) and continuous abstinence rate (CAR) were reported at week 2, 4, 6 and 8. In addition, the oxidative stress status with lipid peroxide and glutathione (GSH) in blood was evaluated before the program and after 2 weeks. Results: The results of 7-day PARs in the control group showed no statistical changes at week 2 (0%), 4 (10%), 6 (20%) and 8 (20%), which was the same in the rDB/CME + placebo group (10%, 20%, 30% and 40%, respectively). Whereas, a significant difference was presented in the rDB/CME+ product group (20%, 60%, 80% and 90% respectively). When comparing between the groups, 7-day PARs at week 2 was not statistically different, but it was in the follow-up period at week 4, 6 and 8. There was no statistical difference at week 4 between the three groups, but there was between the rDB/CME+ product, control and rDB/CME+ placebo groups at week 6 and 8. The results of CAR showed no statistical difference between the control and rDB/CWE+ placebo group in any of the periods. Whereas the rDB/CWE+ product group showed a significant difference after week 4. The CAR was statistically different between the groups after week 6 and 8. At week 6, the CAR of the rDB/CWE+ product group was different to the control group. There was no difference between the control and rDB/CWE+ placebo groups, or between the rDB/CWE+ product and placebo groups. At week 8, the CAR of the rDB/CWE+ product group was different from that of the control, but not from the rDB/CWE+ placebo group. Finally, the GSH level increased significantly in the rDB/CWE + product group when compared to the rDB/CWE+placebo group. Moreover, malondialdehyde (MDA) levels decreased significantly in both the placebo and product groups. In addition, MDA levels showed a significant difference between baseline and after 2 weeks in the rDB/CWE + placebo and product groups. Conclusion: Integrating relaxed-deep breathing with chest mobilization exercise and VC hard candy for 2 weeks can help smoking cessation during consultation, and possibly reduce oxidative stress status among active teenage smokers.

Individuals with long-term illness, disability or infirmity are more likely to smoke than healthy controls: An instrumental variable analysis.

Despite the prevalence of smoking cessation programs and public health campaigns, individuals with long-term illness, disability, or infirmity have been found to smoke more often than those without such conditions, leading to worsening health. However, the available literature has mainly focused on the association between long-term illness and smoking, which might suffer from the possible bidirectional influence, while few studies have examined the potential causal effect of long-term illness on smoking. This gap in knowledge can be addressed using an instrumental variable analysis that uses a third variable as an instrument between the endogenous independent and dependent variables and allows the identification of the direction of causality under the discussed assumptions. Our study analyzes the UK General Household Survey in 2006, covering a nationally representative 13,585 households. We exploited the number of vehicles as the instrumental variable for long-term illness, disability, or infirmity as vehicle numbers may be related to illness based on the notion that these individuals are less likely to drive, but that vehicle number may have no relationship to the likelihood of smoking. Our results suggested that chronic illness status causes a significantly 28% higher probability of smoking. The findings have wide implications for public health policymakers to design a more accessible campaign around smoking and for psychologists and doctors to take targeted care for the welfare of individuals with long-term illnesses.

Peer mentoring for smoking cessation in public housing: A mixed-methods study.

Tobacco use disproportionately affects low-income African American communities. The recent public housing smoke-free policy has increased the demand for effective smoking cessation services and programs in such settings. This mixed-method pilot study explored feasibility and potential impact of a peer-mentoring program for smoking cessation in a public housing unit. The quantitative study used a quasi-experimental design while qualitative data were collected via focus group discussions with peer mentors and participants. Three residents of the public housing complex were trained as peer mentors. Each peer mentor recruited up to 10 smokers in the residence and provided them individual support for 12 weeks. All participants were offered Nicotine Replacement Therapy (NRT). A follow-up investigation was conducted 3 months after completion of the 12-week intervention. At baseline and follow-up, the participants' smoking status was measured using self-report and was verified using exhaled carbon monoxide (eCO) monitoring. The intervention group was composed of 30 current smokers who received the peer-mentoring intervention. The control group was composed of 14 individuals. Overall mean eCO levels dropped from 26 ppm (SD 19.0) at baseline to 12 (SD 6.0) at follow-up (P < 0.01). Participants who were enrolled in our program were more likely to have non-smoking eCO levels (<7 ppm) at follow-up (23.3%) compared to those who did not enroll (14.3%). Our program is feasible for low-income predominantly African American communities. Using peers as mentors may be helpful in providing services for hard-to-reach populations. Given the non-randomized design of our study, randomized trials are needed to test the efficacy of our program in the future.

Lung cancer screening in Lebanon: Joint statement from the Lebanese Pulmonary Society and the Lebanese Society of Medical Oncology

Lung cancer is the leading cause of cancer mortality worldwide. The 5‑year survival rate of patients is ~15%, since the majority of patients present with the disease at an advanced stage. The resulting burden from this disease entails solid efforts towards early detection and smoking cessation. In Lebanon, the triad of high incidence and mortality from lung cancer, extensive tobacco consumption and delayed diagnosis calls for urgent actions. Furthermore, lung cancer screening with a low‑dose computed tomography (CT) scan allows for the early detection and reduces mortality rates, as documented in several randomized trials and meta‑analyses and recommended by international relevant societies. A panel of Lebanese lung cancer experts, members of the Lebanese Society of Medical Oncology and the Lebanese Pulmonary Society, have convened and discussed all aspects and challenges related to lung cancer screening implementation in Lebanon. Accordingly, national guidelines were proposed in this joint statement, which defines the particular high‑risk population that would most benefit from screening. Pillars to success involve a solid, evidence‑based national program, efficient smoking cessation programs and proper referral and follow‑up. In parallel, the quality and logistical basic requirements must be optimized with well‑equipped centers, trained personnel and expert radiologists; in addition to promoting awareness, adherence and sustainability. Physicians need to be trained to ensure accurate risk stratification for the screening and proper referrals from different specialties. Awareness should also be raised in the general population on the safety and benefits of low‑dose CT, and to encourage smoking cessation via dedicated programs. In a country where the economic situation is challenging, and where third‑party payers are resistant to cover screening initiatives, support from the Lebanese Ministry of Public Health is warranted, along with a cost‑effectiveness analysis to uncover the elevated cost of treating advanced stage lung cancer.

Gender Differences Among Out-of-School Korean Adolescents in a Counselor-Visiting Smoking Cessation Program.

The purpose of this study was to explore the determinants of self-reported smoking cessation among out-of-school Korean adolescents who participated in a counselor-visiting smoking cessation program. This retrospective descriptive study analyzed data from the Korea Health Promotion Institute. Participants were enrolled between June 1, 2015, and December 31, 2017, at a regional smoking cessation center in a counselor-visiting smoking cessation program for out-of-school adolescents. Participants consisted of 807 adolescents (70.3% male) with a mean age of 16.9 ± 1.2 years. Multiple logistic regression analysis showed that female gender (OR = 1.54-1.92), cohort year 2016 (OR = 1.69-1.90), smoking more than half a pack a day (OR = 0.44-0.50), strong motivation to quit (OR = 1.44), and number of counseling in person (OR = 1.97-2.10) were statistically significant independent contributors to quitting, based on follow-up assessments at 4 weeks, 12 weeks, and 6 months. This study explored smoking cessation outcomes of a government-driven smoking cessation program that targeted out-of-school adolescents and identified several risk factors that affect a successful outcome. More research is necessary to evaluate the efficacy of such smoking cessation programs for marginalized or understudied populations.

Potential uses of cytisine for smoking cessation in menopausal women - literature summary.

Menopause is a vital stage in which the risk of the appearance of metabolic syndrome and cardiovascular diseases is increased. Cardiovascular risk in menopausal women must be monitored because it is one of the most common causes of mortality in these women. Smoking is an important risk factor for the development of many diseases, including cardiovascular diseases, so promoting smoking cessation in these women is important for the maintenance of cardiovascular health. Current smoking cessation programs mainly include nicotine and varenicline as therapeutic agents, due to their history of success, safety, and efficacy in aiding in cessation, but they do not include "new" agents such as cytisine as coadjuvant in the elimination of the habit of smoking. Cytisine is a therapeutic agent traditionally used in Eastern Europe, which has demonstrated efficacy and safety in smoking cessation, also showing other new pharmacological actions. It has been widely used since World War II as a nicotine substitute. These pharmacological actions, together with their efficacy in smoking cessation, should be explored to evaluate the convenience of the use of cytisine in premenopausal and postmenopausal women, so that cytisine can be identified as a useful therapeutic tool in smoking cessation programs and in particular in menopausal women.

Abstract B005: Decídetexto: Assessment of weight change after smoking cessation treatment in Latino smokers

Abstract Objective: The objective of this study is to describe weight change among Latinos participating in a randomized, culturally appropriate mobile smoking cessation intervention. Background: More than 60% of cancer-related deaths in the U.S. are attributed to tobacco use, poor nutrition, and physical inactivity. Weight gain is one of the possible barriers to smoking cessation success. The obesity rate among Latinos (44.8%) is the second-highest rate among all racial and ethnic groups. Furthermore, Latino adults have the highest rate of inactivity and 75% of Latinos do not meet the recommended levels of fruit/vegetable consumption. Therefore, the relationship between smoking cessation and weight gain among Latinos is an important aspect to consider in smoking cessation treatment for these underrepresented communities. Methods: The present study describes the weight change of participants in a culturally-tailored mobile smoking cessation program (Decídetexto) over six months. Participants were randomized to one of two conditions: 1) Decídetexto, or 2) standard care (printed materials, referral to quitline). Baseline and 6-month follow-up assessments were performed. The cessation outcome was cotinine-verified 7-day point prevalence abstinence. Weight and BMI were compared from baseline to 6-month to verify the impact of smoking cessation on weight. These changes were also compared from baseline to 6-month among intervention participants vs standard treatment participants to assess any impact of the intervention on weight. Results: Subjects (n=348) had complete weight information to be included in this analysis. Most participants were in the overweight and obese BMI categories at baseline (n=259, 74.4%). At 6 months, there was no significant change in BMI status among all participants. Weight change among those who quit at 6 months compared to those who did not quit smoking was also not statistically significant (p=.70). Quitters had an overall higher amount of absolute weight gain by one pound compared to non-quitters at 6 months (5.04±5.02 lbs vs 4.31±4.09 lbs, respectively) which was not statistically significant (p=0.33). In both the intervention and control groups, more subjects did gain weight overall (n=60,36.2% vs n=69,37.9%, respectively). More subjects lost weight in the control group compared to the intervention group (n=55,30.22% vs n=48,28.9%, respectively). Approximately one-third of both the intervention and control groups did not change their weight (n=58,34.9%, vs n=58,37.9%). There was no statistically significant difference between groups in any weight change direction (p=0.95). Conclusion: Participants in a culturally-tailored mobile smoking cessation program for Latino smokers did not experience significant changes in weight compared to standard treatment. Importantly, those who quit smoking also did not experience significant changes in weight. This is an outcome that could inform future counseling of participants in smoking cessation programs, as fear of weight gain is a significant barrier to quit success. Citation Format: Katherine K.S. Rieth, Evelyn Arana, Francisco Cartujano-Barrera, Scott McIntosh, Ana Paula Cupertino. Decídetexto: Assessment of weight change after smoking cessation treatment in Latino smokers [abstract]. In: Proceedings of the 15th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2022 Sep 16-19; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr B005.

Efeito do Programa de Cessação do Tabagismo: uma revisão dessa política pública para dependência tabágica

Abstract Objective Brazil Health Ministry’s guidelines for tobacco control include the Smoking Cessation Program, developed by the Instituto Nacional de Câncer of Brazil. This review aims to describe the studies in which this Program has been applied, reviewing its procedures, effects, potential and limitations. Method Articles from PubMed, PsycINFO, Virtual Health Library and Scientific Electronic Library Online, published between 2002 and 2019, were evaluated, using the descriptors “Smoking Cessation Program” and “smoking cessation” in Portuguese, Spanish and English. A total of 1670 articles were pre-selected, of which 15 resulted eligible for final assessment. Results The results showed adherence rates from 33% to 100%, success rates from 15% to 85% after the intervention and 21% to 51% six months after treatment completion. This variability may be related to the lack of standardization and poor fidelity in the application of the Program, which intends to treat physical, psychological and behavioral dependence. Conclusion Investment in technical training and record monitoring is suggested.

The Impacts of Supervised Exercise Intervention on Tobacco Withdrawal Symptoms.

This study examined a supervised moderate-intensity aerobic exercise programme's effectiveness in regulating the Tobacco Withdrawal Symptoms (TWS) during temporary abstinence. This was a single group, pre and post-quasi intervention study. Thirty daily smokers participated in an 8-week supervised moderate-intensity aerobic exercise programme. We assessed the TWS, smoking urge, mood and stress-pleasure related hormonal variables after the aerobic exercise intervention. The measurements were conducted after overnight abstinence at baseline, post-intervention (at week-8) and post-detraining (at week-10). TWS components, smoking urge and mood were found to improve. For hormonal variables, cortisol and beta-endorphin except adrenaline showed insignificant changes at post-intervention and de-training. The findings suggest moderate-intensity exercise might help in reducing withdrawal symptoms and its adverse effects. Thus, exercise is an effective adjunct treatment in a smoking cessation programme.

A study on clinical, radiological, and histopathological correlation of lung cancer

Background: In developed countries, lung cancer is the most common cause of cancer-related death for both men and women. In the last three decades, its incidence and mortality rates have decreased. Contrary to this, lung cancer remains a major cause of death and incidence in developing nations. Smoking is responsible for most lung cancer deaths. Aims and Objectives: The aim of the study was to study the clinical presentations, the radiological and histopathological appearance of lung cancer and various factors contributing to lung cancer. Materials and Methods: All clinically suspicious patients who came to SSG hospital were sent for radiological and histopathological confirmation for lung cancer. Hence, a total of 50 patients were selected during the period of December 2020–December 2021. Results: Out of the total of 50 cases, male to female ratio was 4.5:1. The prevalence of smoking was 66% (n = 33). All smokers were male. The most common histological subtype was Squamous cell carcinoma (n = 25.50%), followed by adenocarcinoma (n = 15.30%) and small cell carcinoma in 10 patients (20%). The most common metastasis was lymph node metastasis (n = 9.43%), followed by liver metastasis (n = 4.19%) and vertebral metastasis (n = 4.19%). Smoking is the principal risk factor for lung cancer. Conclusion: Histologically, squamous cell carcinoma remains the most common. A poor prognosis is associated with patients who were diagnosed late in the disease. Hence, smoking cessation program and screening program for the detection of lung cancer are essential.

Abstract A111: Smoking cessation and relapse among Black and White patients referred for lung cancer screening

Abstract Background: Tobacco quit rates in the adult U.S. population range from 4% to 8% annually. Lung cancer screening (LCS) provides an opportunity for discussion of smoking cessation. Outside of LCS, Blacks have been shown to make more quit attempts and have higher readiness to quit, but have lower quit rates among current smokers and higher relapse rates among former smokers. In this study, we determined quit and relapse rates after a provider referral for LCS in Black and White patients. Methods: We conducted an observational study within an integrated health system that has both a LCS program and an independent smoking cessation program. Patients, aged 55-77 years who received at least one provider referral (order) for LCS between September 2016 and April 2022 and a second order within 9-36 months, were included in this study.Smoking status was captured in LCS orders. Demographic variables, completion of a low-dose screening CT (LDSCT), smoking cessation counseling referral and medication prescription were captured from the electronic medical record. Pearson Chi-squared test and multivariable logistic regression were used to determine group differences and important predictors of tobacco quit and relapse. Results: During the study period, 6,096 patients (21% Black) received a referral to LCS and 75% of these patients completed an LDSCT between orders. Among current smokers (N=3715) the quit rate was 14% and relapse occurred in 10% of former smokers (N=2381), overall. Rates of quit (12.0% LDSCT no vs. 14.6% LDSCT yes, p=0.048) and relapse (13.7% LDSCT no vs. 9.4% LDSCT yes, p=0.006) were worse for those who did not complete the LDSCT between orders. Black patients had lower quit (11% vs. 14%, p=0.003) and higher relapse (13.6% vs. 9.7%, p=0.03) rates than Whites. Among Black former smokers who did not complete the LDSCT, the relapse rate was nearly 20% and these patients received referrals to counseling and prescriptions for cessation medications at higher rates than White former smokers. In multivariable models, older age, receiving a prescription for a cessation medication, and completing the LDSCT were associated with smoking cessation, while Black race and receiving a referral for counseling were associated with lower odds of quitting. Black race and longer duration between orders were associated with greater likelihood of relapse, while older age and completing the LDSCT were associated with lower likelihood of relapse. Discussion: Rates of smoking cessation appear higher in patients referred for LCS than in the general population. In the context of LCS, Black patients still have lower quit and higher relapse rates than White patients. Relapse is particularly high in Black former smokers who do not complete LDSCT after a referral for screening. Lung screening and smoking cessation programs will need to work together to find culturally appropriate resources and ways to reach out to patients referred for screening, especially those who do not complete the LDSCT, to encourage quitting and provide equitable cessation support. Citation Format: Christine Neslund-Dudas, Amy Tang, Katie Zarins, Elizabeth Alleman, Amanda Holm, Vritti Gupta, Michael Simoff. Smoking cessation and relapse among Black and White patients referred for lung cancer screening [abstract]. In: Proceedings of the 15th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2022 Sep 16-19; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr A111.

Need for workplace smoking cessation program among public transit drivers: Evidence from a cross-sectional study in a metropolitan city of Western India.

Air pollution is a significant contributor to respiratory illness globally, and in India, evidence is scarce on whether smoking exacerbates this problem. We aimed at assessing if being a smoker among public transit drivers increased risk for respiratory illnesses and affected performance of pulmonary function tests in a cross-sectional study in a metropolitan city of Gujarat, western state of India. We conducted a cross-sectional study among public transit drivers (those who were smoking and not smoking). Administration staff who were not smoking were considered as control group. We collected socio-demographic and medical history including occupational history (N = 296). We collected details of respiratory symptoms with standard tools and assessed pulmonary function tests (PFT) using spirometry. Group differences and regression analyses were conducted in R software. We found that respiratory symptoms among public transit drivers who smoked were higher than those who did not smoke and healthy controls. In PFT diagnosis, drivers who smoke displayed two times higher prevalence of obstructive pattern compared to drivers who did not smoke. There was a significant reduction in the larger as well as the smaller airway functions, reflected in reduction of FEV1/FVC ratio (p < 0.001) and FEF25-75% (p < 0.001), respectively, among drivers who smoked compared to controls. Our results indicate that being a driver with a smoking history leads to a 3.1% greater decrease in the FEV1/FVC ratio and about half a litre reduction in FEF25-75% compared to the drivers who did not smoke. We suggest there is a high need for smoking cessation programmes for public transit drivers as they are at higher risk for respiratory illnesses and reduced pulmonary functions when smoking is added to the existing vehicular exposure.

Effective Timing of Introducing an Inpatient Smoking Cessation Program to Cancer Patients.

We aimed to identify factors influencing smoking cessation success among cancer patients registered in an inpatient smoking cessation program at a single cancer center. The electronic medical records of enrolled patients with solid cancer were retrospectively reviewed. We evaluated factors associated with 6-month smoking cessation. A total of 458 patients with cancer were included in this study. Their mean age was 62.9±10.3 years, and 56.3% of the participants had lung cancer. 193 (42.1%) had not yet begun their main treatment. The mean number of counseling sessions for the participants was 8.4±3.5, and 46 (10.0%) patients were prescribed smoking cessation medications. The 6-month smoking cessation success rate was 48.0%. Multivariate analysis showed that younger age (<65 years), cohabited status, early stage, and the number of counseling sessions were statistically significant factors affecting 6-month smoking cessation success (p<0.05). Initiation of a cessation program before cancer treatment was significantly associated with cessation success (odds ratio, 1.66; 95% confidence interval, 1.02-2.70; p=0.040). Smoking cessation intervention must be considered when establishing a treatment plan immediately after a cancer diagnosis among smokers.

Abdominal aortic aneurysm growth rates are not correlated to body surface area in screened men.

Screening for abdominal aortic aneurysm (AAA) in 65-year-old males reduces aneurysm related mortality. Infrarenal aortic diameter (IAD) has been shown to correlate to body surface area (BSA) which could influence diagnostic criteria for AAA. This study investigates whether AAA growth rates are also dependent on BSA, as that might have potential effects on surveillance of small AAAs. We conducted a retrospective, single center cohort study of 301 men with screening detected AAA between 2010-2017 with surveillance to 2021. AAA growth rates were analyzed in relation to the subject's BSA, smoking habits, and diabetic disease using a linear mixed-effects model. All men were offered smoking cessation program, optimized medical treatment, and advice on physical activity. The screening program included 28,784 men. Of the 22,819 (79%) attending the examinations, 374 men (1.6%) were found to have an AAA out of which 301 men had undergone two or more examinations during surveillance and were included with a median follow-up of 1846 days (IQR: 1 399). Mean unadjusted AAA growth rate was 1.60 mm/year (95% CI: 1.41-1.80). Diabetes mellitus had a statistically significant negative impact, smoking had a statistically significant positive impact on AAA growth rates whereas no correlation between AAA growth rate and BSA could be found. Body surface area could not be found to have a statistically significant correlation to AAA growth rates. The impact of smoking and diabetes on AAA growth rates remains similar to previously reported.

Situational analysis of the smoking cessation program in a Brazilian capital during the COVID-19 pandemic.

Smoking is a public health problem associated with high morbimortality. Smoking cessation services, although effective, have limited reach and have been compromised by the pandemic. This study aimed to analyze the care for smokers in João Pessoa (PB), Brazil, during the COVID-19 pandemic. A descriptive, exploratory, and quantitative study was conducted in two phases: a survey of health indicators and an evaluation of sociodemographic profiles of professionals and service clients during the study years. Seven professionals, smoking group coordinators, and 20 clients participated in the research. The results showed low program coverage, with a declining number of smokers treated during the pandemic, down from 419 in 2019 to 129 in 2020. Interviews identified the program's positive aspects and limitations, good effectiveness, and low access, especially in primary health care. Tobacco consumption and risk reduction strategies during the COVID-19 pandemic originated from services and professionals involved. We can conclude that the National Tobacco Control Program has an incipient implementation in primary health care in this region and that the number of services offered was reduced during the pandemic, decreasing demand and actions.

Hospitalised Smokers' and Staff Perspectives of Inpatient Smoking Cessation Interventions and Impact on Smokers' Quality of Life: An Integrative Review of the Qualitative Literature.

To identify, integrate, and appraise the evidence on hospitalised smokers' and staff perspectives of inpatient smoking cessation interventions and the impact on smokers' quality of life. The integrative review method was used to present hospitalised smokers' and staff perspectives of inpatient smoking cessation interventions. Search Method. This integrative review consisted of a comprehensive search on smoking cessation interventions that take place during an inpatient admission to hospital for adults (> age 18 years) of the following online databases: Ovid Medline, Joanna Briggs Institute, APA PsycInfo, CINAHL, Cochrane, Google Scholar, PEDro, and Scopus. The search strategy was inclusive of peer-reviewed studies limited to the English language or translated to English. A search of grey literature and manual searching of reference lists was also conducted to identify further studies not identified in the online database search. All studies that produced any qualitative data (i.e., qualitative, mixed methods, and surveys) on inpatient-initiated smoking cessation programs were included. Outcomes of interest are included but were not limited to education, counselling, and the use of pharmacotherapy. Studies undertaken in the psychiatric, adolescent, and paediatric settings were excluded. The key findings from this integrative review included positive evaluations from both patients and staff involved in inpatient smoking cessation interventions, reporting that hospitalisation was an appropriate opportunity to address smoking cessation. A number of facilitators and barriers to inpatient smoking cessation interventions included creating a supportive patient-centred environment and consideration of the cost of nicotine replacement therapy and time to deliver inpatient smoking cessation interventions. Recommendations/preferences for future inpatient smoking cessation interventions included the use of a program champion and ongoing education to demonstrate the effectiveness of the intervention, and despite the cost of nicotine replacement therapy being identified as a potential barrier, it was identified as a preference for most patients. Although quality of life was only evaluated in two studies, statistically significant improvements were identified in both. This qualitative integrative review provides further insight into both clinician and patient participants' perspectives on inpatient smoking cessation interventions. Overall, they are seen to produce positive benefits, and staff training appears to be an effective means for service delivery. However, insufficient time and lack of resources or expertise appear to be consistent barriers to the delivery of these services, so they should be considered when planning the implementation of an inpatient smoking cessation intervention.

Association between smoking and colorectal cancer in Eastern Mediterranean Regional Office (EMRO): A systematic review and meta-analysis.

Smoking poses a significant risk for colorectal cancer (CRC), considered the third leading reason for cancer-related deaths worldwide. However, there has been limited research on the relationship between smoking and CRC in the Eastern Mediterranean Regional Office (EMRO). Therefore, a meta-analysis was conducted to combine available data and gain a comprehensive understanding of the relationship between smoking and CRC in EMRO. Two independent researchers searched PubMed, Scopus, and Web of Science until December 2022. The included studies were checked for risk of bias administering the Newcastle-Ottawa scale. Heterogeneity was evaluated using I2 statistics and the Cochrane test. Publication bias was determined through funnel plot analysis and Egger's regression test. Additionally, a meta-regression analysis explored the impact of a country's Human Development Index (HDI) on the relationship between smoking and CRC. The final analysis included 26 studies, revealing a significant association between smoking and CRC (OR = 1.40; 95% CI: 1.11 - 1.78; P = 0.004). Moreover, smoking had a more pronounced adverse effect on CRC in countries with higher HDIs compared to those with lower HDIs (OR = 1.30; 95% CI: 0.99 - 1.71; P = 0.054). Our findings underscore the importance of implementing smoking cessation programs and policies in EMRO countries, as they demonstrate a positive relationship between smoking and the risk of CRC. Furthermore, the results suggest that a country's level of human development may influence the association between smoking and CRC. Further research is needed to investigate this potential connection and develop targeted public health interventions.

Effect of Smoking Cessation Program: a review of this public policy for tobacco dependence

Resumo Objetivo Entre as diretrizes do Ministério da Saúde para controle do tabagismo está o Programa de Cessação do Tabagismo, desenvolvido pelo Instituto Nacional do Câncer. Esta revisão objetiva descrever as pesquisas que aplicaram o Programa de Cessação do Tabagismo, analisando seus procedimentos, efeitos, potencialidades e limitadores. Método Foram avaliados artigos das bases PubMed, PsycINFO, Biblioteca Virtual da Saúde e Biblioteca Eletrônica Científica Online publicados entre 2002 e 2019 e encontrados através de busca que usou os descritores: “Programa Nacional de Controle do Tabagismo” e “cessação do tabagismo” em português, espanhol e inglês. Foram pré-selecionados 1670 artigos, dos quais 15 foram elegíveis para análise final. Resultados Os resultados mostraram taxas de adesão ao tratamento de 33% a 100%, taxas de sucesso de 15% a 85% após a intervenção e de 21% a 51% seis meses após o final do tratamento. Essa variabilidade pode estar relacionada à falta de padronização e baixa fidelidade na aplicação do Programa, que propõe tratar as dependências física, psicológica e comportamental. Conclusão Recomenda-se investimento em capacitação técnica e monitoramento dos registros.