It is globally acknowledged that small-scale businesses (SSEs) play a critical role in promoting innovation, economic growth, employment creation, and social development in both developed and developing nations. SSEs in Nigeria have not contributed as much to the nation's economic development and progress as was anticipated because of a lackluster level of innovation. The performance of SSEs in Ondo State, Nigeria, was therefore investigated in relation to the development of human capital. Out of 2,324 registered SSEs, data from 270 respondents were gathered using a structured questionnaire and a simple random sampling technique. In order to investigate the relationship between the independent variable (human capital development) and the dependent variable (sales growth), the data were analyzed using simple linear regression and the Statistical Package for Social Sciences (SPSS) version 23. The results of the study showed that increased sales are positively and significantly impacted by the development of human capital (β = 0.752, t = 15.248, P<.005). According to this, sales growth in Ondo State, Nigeria, is strongly predicted by the development of human capital. According to the outcome, the State's sales growth was boosted by 64.7%, in part by human capital development. The study concluded that if sufficient funds are allocated to developing their human capital—particularly through training, seminars, workshops, and the acquisition of academic and professional qualifications—SSEs in Ondo State, Nigeria, can achieve a considerable improvement in both their financial and non-financial performance. Thus, it is therefore recommended that governments, non-governmental organizations, and other interested parties make investments in thorough training and educational initiatives designed to meet the unique requirements of SSEs.