Small Amount Of Fluid Research Articles

Endovascular treatment of traumatic pseudoaneurysm of the ileal branch of the superior mesenteric artery in a 9-year-old girl: Case report and literature review.

Visceral artery aneurysm is a rare and potentially fatal vascular condition that typically affects the superior mesenteric or inferior mesenteric arteries, the splenic, hepatic, and celiac arteries, as well as their branches. Visceral artery aneurysms can usually be treated using endovascular intervention, open surgery, or percutaneous thrombin injection. A 9-year-old girl was admitted to our trauma center with abdominal and bilateral leg pain after a car accident involving a head-on collision. Abdominal computed tomography (CT) showed bowel herniation through a muscle defect in the left lateral abdominal wall. There was a small amount of fluid around the liver and spleen, mild thickening of the small bowel wall, and infiltration in the small bowel mesentery, indicating the possibility of small bowel injury. Emergent exploratory laparotomy was performed. After resection of the ischemic parts of the terminal ileum and sigmoid colon, intestinal continuity was reestablished. Primary repair was performed on a traumatic left lateral abdominal wall hernia. She recovered well postoperatively without any complications. A follow-up abdominal CT scan after 2 months showed a pseudoaneurysm of the ileal branch of the superior mesenteric artery. Despite the absence of any gastrointestinal symptoms, the pseudoaneurysm was treated by endovascular intervention using numerous coils because of the significant risk of delayed rupture or massive bleeding. Follow-up abdominal CT scan after 6 months showed complete occlusion and resorption of the pseudoaneurysm. Although it is technically challenging, endovascular coil embolization may be a feasible technique in children with traumatic visceral artery pseudoaneurysms without complications.

A case of uveitis associated with novel corona-virus inactivated vaccine engineered CHO cells: A case report

Rationale: The pathogenesis and course of recombinant Corona Virus Disease 2019 vaccine (CHO cell) associated uveitis is rarely seen in clinical practice, thus, it is difficult and time-consuming to diagnose. Patient concerns: An adult female patient suffered from binocular visual impairment after receiving the Corona Virus Disease 2019 vaccine. The patient was healthy and had no family history of retinal dystrophy previously. This case showed the following features in multimodal imaging including scattered speckled fluorescein leakage was seen around the optic disc, and the leakage was slightly enhanced in the later stage. The macular area showed about 4 papillary diameter size discoid retinal detachment area fluorescein pool staining. Optical coherence tomography showed retinal choroidal folds above the optic disc, a small amount of fluid under the neuroepithelial layer, and serous detachment of the neuroepithelial layer in the macular area. Diagnosis: Posterior uveitis of both eyes. Intervention: Orally Maizhiling, Ginkgo biloba leaves, and multivitamins. Outcome: After treatment, the symptoms of the patient were significantly improved, and optical coherence tomography reexamination showed exudation had been absorbed. Lessons: The injection of a novel coronavirus-inactivated vaccine (CHO cell) can lead to potential uveitis disorders, which is worthy of clinical attention, but the prognosis of patients is good.

Added value of a connected glucose meter for glycorrhachia assessment

ObjectivesThe aim of this study was to demonstrate the performance and added value of rapid glucose determination in cerebrospinal fluid using a connected glucometer. Design and MethodsIntra-assay and inter-assay accuracies were calculated using residual clinical samples. Accuracies were measured by comparing the results obtained with the glucometer to those from the central laboratory on a large routine chemistry platform. ResultsThe intra-assay coefficients of variation were between 6.1% and 6.2% for low values (18 mg/dL) and between 5.6% and 6.8% for high values (58 mg/dL). The inter-assay coefficients of variation were between 9.4% and 16.3% for the low values (18 mg/dL) and between 5.7% and 8.7% for the high values (pool; ±75 mg/dL). The regression equation by comparison to the central laboratory was y = 4.08 + 0.82 x, with a coefficient of determination (r2) of 0.95. ConclusionsThe measurement of glycorrhachia with a connected glucometer before the analysis in the central laboratory allows a rapid orientation in the deferential diagnosis of a meningitis of viral vs bacterial origin. The response time is fast (6 s) and requires only a small amount of fluid (1.2 μL), which is important in infants, especially since lumbar puncture is an integral part of the investigation of the origin of a fever in this population.

RESPONSE SURFACE METHODOLOGY-BASED NOVEL LATTICE HEAT SINK OPTIMIZATION FOR ELECTROHYDRODYNAMIC (EHD) SPRAY COOLING

In recent years, the size of electronic equipment has become smaller, while the increased processing capacity has led to progressive elevation in the heat flux. As a result of this, the performance of this equipment decreases, and their service lives decrease. Although traditional cooling methods are insufficient to remove the surface heat, new cooling techniques, for example, electrohydrodynamic spray (EHD-spray) cooling, show promise in guaranteeing the operation of these systems under the intended conditions. EHD-spray, also known as electrospray, is an atomization method that provides equal and homogeneous droplets. Although EHD has been used in many studies in the literature, its use in heat transfer has only recently become an important research area. Studies on EHD-spray, which has important advantages such as requiring a very small amount of fluid and low energy, are limited, and there are almost no studies using finned heat sinks. In the study carried out, unique design heat sinks produced by the selective laser melting (SLM) method were optimized with the respond surface method (RSM) Box-Behnken design (BBD) management, that is one of the most effective design methods. In the study where heat sink surface area (HSSA), fluid composition ratio (FCR), and flow rate (FR) were used as variable parameters, the highest heat transfer coefficient (HTC) was found for 100% distilled water at a 17 mL/h flow rate, and the heat sink had the lowest surface area. The results show that EHD-spray is promising for cooling high-heat-flux systems.

One-Way Valve as Management of Chest Tube Ambulation in Pneumothorax Cases

An adequate chest drainage system is the main goal of fluid and air evacuation and restoring negative pressure intrapleural so it can help lung development. The intrapleural is a closed, airtight space filled with a small amount of fluid as a lubricant for lung movement during the breathing process. Accumulation of intrapleural air is known as pneumothorax, and one of the initial management options is the implantation chest tube. Chest tubes, which are connected to a water seal, conventionally show varying results and have shortcomings because they require monitoring and limit patient mobility, so the safety of their use in outpatient settings is questionable. Lungs that are not inflated or have an inflated water seal still show air bubbles even though it has been installed. A chest tube adequate for 48 hours is a condition known as persistent air leak, thus requiring extended usage time from chest tube to the drainage management complex. Use of ambulation management through the use of various tools and equipment devices which can be connected with a chest tube can be an option with the aim of reducing treatment time, lowering funding, increasing comfort and hopefully providing better external results.

Nondestructive Evaluation of Fluid Characteristics using Compact Quarter-Mode SIW Resonator Sensor

Novel compact quarter-mode (QM) substrate integrated waveguide (SIW) resonator sensor based on dielectric properties developed. The sensor works on the principle of material perturbation of the cavity resonator. It operates in the broader range of ISM frequency band to characterize various properties of pure liquids, their admixtures, and soluble solids in the solution. The sensor is excited by a 50-ohm microstrip line. A Teflon tube passes through one end of the sensor to hold the material under test (MUT). The variations in the dielectric constant of the material under test shift the resonant frequency. The simulation result shows adequate shifts in resonant frequency and dielectric constant dependent. Thus, this feature of resonate frequency shift assists in determining the component concentration, adulteration, or various properties depending on specific calibration. The findings suggest that the proposed sensor can be successfully applied to determine properties with high precision using a very small amount of fluid in a novel non-destructive approach.

A Study to Detect Risk Factors of Chronic Subdural Hematoma Recurrence

Introduction: Chronic subdural hematoma (CSDH) is a common type of intracranial hemorrhage in elderly patients. The risk factors for recurrence of chronic subdural hematoma (CSDH) after surgical evacuation has not been completely understood until now, but several risk factors for recurrence have been reported. Meanwhile, the definitive risk factors have not been defined until now. The aim of this study was to study the potential risk factors, including preoperative, operative and post-operative ones for CSDH recurrence. Materials and Methods: The study population comprised of all > 18 year age group patients who were operated for chronic subdural hematoma in Neurosurgery Department of tertiary care center. It was prospective cohort study. Patients who met inclusion criteria, postoperative outcomes were assessed at discharge, then at one month and three months afterwards in the neurosurgery OPD. Both the treatment options i.e. BHC Burr hole craniotomy and minicraniotomy as required as per CT scan or MRI findings. Results: 7 patients (10.7%) had recurrence, of CSDH. All the reoccurrences occurred in burr hole operated patients. There was no recurrence in mini craniotomy operated group. Conclusions: Many risk factors for recurrence of CSDH have been found, including old age, cerebral atrophy, large hematoma, bilateral hematomas, hematoma density, inflammation markers, alcohol ingestion, bleeding tendency, and some technical aspects of surgery such as irrigation with small amount of fluid, not excising thick membrane preventing brain expansion.

Development of an In Vitro Methodology to Assess the Bioequivalence of Orally Disintegrating Tablets Taken without Water.

To assess the probability of bioequivalence (BE) between orally disintegrating tablets (ODTs) taken without water and conventional tablets (CTs) taken with water, an in vitro biorelevant methodology was developed using the BE Checker, which reproduces fluid shifts in the gastrointestinal tract and drug permeation. In addition to the fluid shift from the stomach to the small intestine, the process of ODT disintegration in a small amount of fluid in the oral cavity and the difference in gastric emptying caused by differences in water intake were incorporated into the evaluation protocol. Assuming a longer time to maximum plasma concentration after oral administration of ODTs taken without water than for CTs taken with water due to a delay in gastric emptying, the fluid shift in the donor chamber of the BE Checker without water was set longer than that taken with water. In the case of naftopidil ODTs and CTs, the values of the f2 function, representing the similarity of the permeation profiles, were 50 or higher when the fluid shift in ODTs taken without water was set at 1.5 or 2 times longer than that of the CTs taken with water. The values of the f2 function in permeation profiles of pitavastatin and memantine ODTs were both 62 when the optimized experimental settings for naftopidil formulations were applied. This methodology can be useful in formulation studies for estimating the BE probability between ODTs and CTs.

Preliminary Application of Contrast-Enhanced Ultrasound in the Treatment of Diabetic Ulcers

To investigate the role of contrast-enhanced ultrasound (CEUS) in the treatment of diabetic ulcers. The clinical data of 27 diabetic patients, who underwent CEUS examination of their ulcers in our hospital between April 2021 and July 2022 were collected. Among them, 26 patients suffered from diabetic foot ulcers, 5 of whom underwent amputation during hospitalization, and one patient suffered from hip ulcer. The 27 patients' mean age was (64.08±12.57) years. Fasting blood glucose levels of the patients were 3.36-34.61 mmol/L, with a mean of (10.62±8.77) mmol/L. Their glycosylated hemoglobin levels were 5.80%-10.70%, with an average of 7.96%±1.50%. Philips EPIQ7 ultrasound system with L9-3 linear probe of 3-9 MHz was used. First, the patients' ulcers were examined with conventional ultrasound to observe for abnormal echo. Then, 2.4 mL SonoVue (Bracco, Italy), a contrast agent, was injected intravenously through the elbow to look for effusion/pus, sinus tract, or dead space in the lesion area, and images were acquired. Among the 27 patients, except for 5 with amputation stumps, 22 patients had wound areas ranging from 0.16 cm 2 to 215 cm 2, all being accompanied by sinus tract formation. Ten patients underwent ultrasound examination during their treatment. The positive rate of the results of conventional ultrasound was 50% (5/10) for identifying effusion/pus and pseudoaneurysm in the deep area of ulcers, while the positive rate of CEUS results was 100% (10/10). In addition to the lesions found by conventional ultrasound, CEUS also found large sinus tracts or dead spaces in the deep surface of ulcers in 5 additional patients. Of the 27 patients, 17 underwent ultrasound examination of the healing status of sinus tracts and dead spaces in the deep areas of ulcers before discharge. No sinus tracts in the deep areas of the ulcers were found by conventional ultrasound. However, relatively small dead spaces or sinus tracts in the deep areas of the ulcers were found in 10 patients by CEUS. Conventional ultrasound and CEUS found that 1 patient had a small amount of fluid in the amputation stump. In the remaining 6 patients, no deep sinus tracts in the ulcers were found by either conventional ultrasound or CUES, and the ulcers healed completely. By examining microvascular perfusion in diabetic wounds with CEUS, we can observe the extent of sinus tracts during treatment and whether the sinus tracts have healed or whether there are still dead spaces before patient discharge, which provides support for clinical decision-making concerning the treatment of diabetic ulcers.

On the experimental characterization of the fluid volume influence on the friction between rough surfaces

The load-bearing behaviour of lubricated contacts depends primarily on the normal force, the relative velocity, and the geometry. Thus, with the aid of the Stribeck curve, it is usually well possible to characterize whether hydrodynamics, mixed friction, or boundary friction is more likely to be present. The fact that the load regime can also depend on the fluid quantity is obvious, but has hardly been systematically investigated so far. Especially for contacts with microscopic roughness, the defined application of a very small amount of fluid is a very challenging requirement. In this paper, a very fundamental study shows how a pin-on-disc tribometer can be used to achieve the transition from dry friction via mixed friction to predominant hydrodynamics by the amount of supplied fluid. The experiments are carried out on samples filed with different coarseness. In addition, the simultaneous influence of partial filling and normal force as well as relative velocity is also shown. Very good reproducibility has been practically reached over the entire range of the tests. Regarding the quantities for the coefficient of friction (COF), it was concluded that close to full filling, a reduction of the fluid quantity has a similar effect on the COF as the reduction of the velocity. This property goes along with the common theory of starved lubricated systems. Such behaviour was not observed to the same extent for the normal force. In the vicinity of smaller fluid quantities, the COF increases very rapidly with further reduction in fluid quantity, far more disproportionately than that with reduction in velocity. With a deeper understanding of this problem, various practical issues such as idling or the run-up process in bearings can also be studied in a more focused manner.

Spontaneosus Pneumothorax

Background: Pneumothorax is a medical emergency which is defined as an abnormal condition where there is air in the pleural cavity which physiologically contains only a small amount of fluid. Pneumothorax can arise spontaneously or as a result of trauma. Method: The method used in this study is a literature review. The literature study conducted by the author is by searching various written sources, whether in the form of books, archives, magazines, articles and journals, or documents that are relevant to the problem being studied. Discussion: Pneumothorax is classified as primary spontaneous if it occurs in the absence of basic lung disease or thoracic trauma. Pneumothorax is classified as secondary spontaneous if it is caused by basic lung disease. The etiology of primary spontaneous pneumothorax is pleural bleb and bulla. A bleb (air pocket) or bulla is a small air-filled pocket that forms between the lung and pleural tissues. The risk factors associated with pneumothorax are smoking and body thinness. Conclusion: The initial management of spontaneous pneumothorax includes emergency management. Furthermore, management can be divided into conservative and invasive management

Current Aspects on the Management of Perforated Acute Diverticulitis: A Narrative Review.

Unhealthy nutritional habits and the current western lifestyle have led to an increased incidence of acute diverticulitis, which mainly affects older patients. However, the disease course in younger patients might be more severe. It has a continued increase in surgical practice, as it is the most common clinical condition encountered in the emergencies. Diagnosis and management have changed over the past decade. C-reactive protein > 170 mg/L represents the cut-off point between moderate and severe diverticulitis, and a CT scan is mandatory. It demands urgent surgical management and has high morbidity and mortality rate, especially in immunosuppressed patients, reaching up to 25%. According to the contemporary guidelines, there have been certain indications for conservative management and re-evaluation (administration of antibiotics, CT-guided drainage of the abscess, when it is > 4 cm). They include pericolic air bubbles or a small amount of fluid, absence of abscess within a distance of 5 cm from the affected bowel or abscess ≤4 cm. In other cases, Hartmann’s sigmoidectomy is the procedure of choice. An alternative choice, nowadays, is resection and primary anastomosis with or without diverting stoma, especially in younger patients. Laparoscopic lavage only versus primary resection has been performed in severe cases of Hinchey III or IV. Damage control surgery, possible open abdomen, and reoperation are recommended in severe sepsis. Hinchey’s classification may not be absolutely adequate, and several modifications have been proposed. Current classification criteria (CRP, qSOFA score) are more appropriate. The decision-making must be individualized depending on the hemodynamic status (septic shock), age, comorbidity, immune status, intraoperative findings, and MPI (Mannheim peritonitis index).

Computational fluid dynamics and machine learning as tools for optimization of micromixers geometry

Microfluidic devices have become a new trend in different fields and have attracted attention due to their compact size and capability to deal with a small amount of fluid. Micromixing is an efficient way to mix miscible fluids at this microfluidic level. This work explores a new approach for optimization in microfluidics, using CFD (Computational Fluid Dynamics) and ML (Machine Learning) techniques. The objective of this combination is to enable global optimization with lower computational costs. A Y-type micromixer inspires the initial geometry with cylindrical grooves on the surface of the main channel and obstructions inside it. Simulations for circular obstructions were carried out using the OpenFOAM software to observe the influence of these obstacles. The effects of obstruction diameter and its offset on the percentage of mixing, pressure drop and energy cost were investigated. Numerical experiments were analyzed using machine learning. A neural network was used to train the dataset composed of obstruction diameter and its offset as inputs and percentage of mixing and pressure drop as outputs. The genetic algorithm was used to find the geometry that offers the maximum value of the percentage of mixing and the minimum pressure drop value. The optimal value obtained for the obstruction diameter was 131 mm and for its offset 10 mm, which corresponds to obstructions of medium size close to the channel wall. It is worth mentioning that each simulation takes around 4h, and the total time to guarantee the global optimization would be about 25.000 days. With this methodology, the dataset production, training and optimization takes 40 days. This procedure is a tremendous advantage for microfluidic optimization.

Tourmaline as a recorder of the magmatic-hydrothermal evolution in the formation of pegmatite: In-situ elemental and boron isotopic compositions of tourmaline from the Qinghe pegmatite, Chinese Altay orogen

• Tourmalines record the magma-hydrothermal evolution of pegmatite-forming magma . • Extremely low REEs of tourmaline indicate direct melting of metapelite to form pegmatite . • Boron isotopic variation reflects the scale of fluid exsolution during pegmatitic evolution. We conducted elemental and boron isotope studies on tourmalines from a single pegmatite dyke of the Altay orogen to investigate its origin and evolution. The pegmatite dyke is composed of border, intermediate and core zones. The border and intermediate zone tourmalines mostly belong to schorl, while the core zone and magmatic hydrothermal tourmalines to dravite. Most tourmalines follow the (Na + Mg) (Al + X vac ) -1 , FeMg -1 and MnMg -1 exchange vectors. The core zone tourmalines show positively correlated FeO t and MgO, and negatively correlated FeO t and Al 2 O 3 , suggesting a rise of f O2 in this zone. Moreover, they show higher B, Mg, Sr and Eu than other tourmalines due to magmatic evolution. Tourmaline from the Altay pegmatite is characterized by extremely low REE abundances (<3 ppm) when compared with those from granites, suggesting an origin from direct melting of metapelitic rocks. The border and intermediate zone tourmalines have comparable boron isotopic compositions with δ 11 B = −14.0 to −12.2‰, which are similar to the mica schist (−13.2 ‰ to −12.2‰), but slightly heavier than the core zone and magmatic hydrothermal tourmalines (−14.4‰ to −13.3‰). This suggests derivation of the pegmatite from melting of the metapelite without causing boron isotope fractionation, whereas late-stage fluid exsolution caused somewhat boron fractionation. This may be indicative of only small amounts of fluids being released from the barren pegmatite-forming magma. Tourmalines from mineralized pegmatites basically exhibit heavier boron isotope compositions than those from barren pegmatites, due probably to more involvement of evaporate in the source of the former.

Female ejaculation and squirting as similar but completely different phenomena: A narrative review of current research.

Women expel fluids of various quantities and compositions from the urethra during sexual arousal and orgasm. These are classified as either female ejaculation (FE) or squirting (SQ). The aim of our analysis was to present evidence that FE and SQ are similar but etiologically different phenomena. A review of studies was performed on fluids expelled from the urogenital tract during female sexual activities using the Web of Knowledge™ (Web of Science Core Collection) and MEDLINE (Ovid) databases from 1946 to 2021. Until 2011, all female orgasmic expulsions of fluids were referred to as FE. The fluid was known to be either from the paraurethral glands or as a result of coital incontinence. At present, SQ is considered as a transurethral expulsion of approximately 10 milliliters or more of transparent fluid, while FE is considered as a secretion of a few milliliters of thick fluid. The fluid in SQ is similar to urine and is expelled by the urinary bladder. The secretion in FE originates from the paraurethral glands and contains a high concentration of prostate-specific antigen. Both phenomena can occur simultaneously. The mechanisms underlying SQ and FE are entirely different. SQ is a massive transurethral orgasmic expulsion from the urinary bladder, while FE is the secretion of a very small amount of fluid from the paraurethral glands.

Features of chronic heart failure in COVID-19 pandemic

RelevanceCurrent and past coronavirus infection can provoke and aggravate the course of previous chronic heart failure by initiating the processes of thrombus formation, inflammation and fibrinogen synthesis, affecting the pleuropericardial space, increasing the load on the right heart due to pulmonary hypertension.Purpose of the studyTo identify the features of chronic heart failure after COVID-19 infection with lung damage.MaterialAn open cohort prospective study of 50 patients was carried out. Inclusion criteria: the presence of a positive brain natriuretic peptide and echocardiographic changes corresponding to systolic or diastolic dysfunction before the onset of the pandemic, signed informed consent. The diagnosis of COVID - 19 was confirmed by a positive PCR test and the presence of M and G antibodies, lung damage - by the results of computed tomography of the lungs.MethodsStandard clinical examination, quality of life questionnaire, echocardiography with measurement of cavity volume, indicators of left ventricular systolic and diastolic function, size and function of the right ventricle. The second examination was carried out one month after hospitalization.ResultsThe features of the clinical picture were an increase in shortness of breath (38 people, 86%), a decrease in exercise tolerance (40 people, 90%), an increase in chest pain (25 people, 60%), palpitations (40 people, 90%). On echocardiography, the most frequent dynamics compared to the 2019 echocardiography indicators were an increase in pressure in the pulmonary artery (44 people, 100%), the size of the right (38 people, 86%) and left ventricles (30 people, 68%), left atrium (38 people, 86%), an increase in the severity of valvular regurgitation (44 people, 100%) and a decrease in the ejection fraction within the “gray zone” (38 people, 86%). The newly emerging decrease in EF below 45% was recorded much less frequently, in 13 people (30%). In 40 (80%) patients, certain signs of deterioration of left ventricular diastolic function were revealed: dilatation of the left atrium, decrease in the mean e, increase in E/e' according to tissue Doppler ultrasonography. The TAPSE index, which characterizes the global function of the right ventricle, practically did not decrease. Frequent findings during echocardiography one month after the disease were a small amount of fluid in the pericardial cavity (30 people, 68%) and pleuropericardial adhesions.ConclusionThe clinical condition of patients with CHF in the first month after a previous infection with COVID-19 with lung involvement corresponded to a worsening of CHF with rhythm disturbances and instability of blood pressure, which on echocardiographic examination was manifested by dilatation of the heart cavities, valvular regurgitation, diastolic dysfunction of the left ventricle and increased pressure in the arteries.Funding AcknowledgementType of funding sources: None. Dynamics of echocardiography in patients

Особливості способу життя як фактор ризику розвитку і прогресування діабетичної ретинопатії у хворих на цукровий діабет 2-го типу

Актуальність. На сьогодні активно вивчається роль загальної дієти, окремих харчових продуктів і поживних речовин, способу життя (CЖ), фізичної активності тощо у розвитку цукрового діабету 2-го типу (ЦД2). Мета — провести аналіз особливостей способу життя як фактора ризику розвитку і прогресування діабетичної ретинопатії (ДР) у хворих на цукровий діабет 2-го типу. Матеріали та методи. Дослідження включало 76 хворих із ЦД2, у яких за результатами офтальмологічного обстеження виявлено різний ступень ДР. Контрольну групу (n = 43) становили особи без ЦД, співставні із пацієнтами за статтю, віком, індексом маси тіла. Для вивчення СЖ була розроблена анкета, на питання якої пропонували відповісти всім досліджуваним особам. Результати. Для інтегральної оцінки показників СЖ в групах порівнянь доцільно проводити аналіз відповідей анкети через визначення індексів. Найбільш вдалим виявився індекс раціональності рекомендації через відношення «рекомендовано — не рекомендовано». 90 % хворих із ЦД2 дотримуються спеціальної дієти, але наявність погрішностей при дієтичному харчуванні не корелює прямо із тяжкістю стану і розвитком ДР. Додаткове фізичне навантаження, як і вживання додаткової кількості води в раціоні є звичками, які суттєво відрізняють хворих із ЦД2 від їх ровесників без діабету. Але відсутність додаткових фізичних вправ і невелика кількість рідини при щоденному вживанні не виявили кореляції із погіршенням стану і посиленням ускладнення у вигляді ДР. Аналіз харчових звичок показав, що недостатність вживання фруктів і овочів знаходиться в прямій залежності із захворюванням на ЦД і його ускладненням у вигляді прогресування ДР. Висновки. Отримані дані надають підставу сформувати рекомендацію для пацієнтів з ЦД2 у вигляді збагачення раціону харчування фруктами й овочами і розглядати цю пораду як профілактичний засіб розвитку захворювання й ускладнення у вигляді прогресування ДР.

THE CASE OF ISOLATED APPENDICEAL ENDOMETRIOSIS MIMICKING APPENDICITIS

Endometriosis is the presence of endometrial tissue outside the uterine cavity. It is mostly seen in the pelvis but can also affect the extrapelvic areas of the body. Gastrointestinal (GI) tract is the most frequently affected extrapelvic site and rarely involves the appendix. When it occurs, may mimick appendicitis. We present a childbearing-age woman suffering from right lower quadrant (RLQ) pain. Her complaint was repeating cyclically for 8 months. Abdominal ultrasound (US) disclosed wall thickening at tip of the appendix and small amount of fluid around it, suggesting distal appendicitis. Computed tomography (CT) depicted approximately a 1 cm nodulary mass on tip of the appendix. Then appendectomy was performed and histopathological examination yielded appendiceal endometriosis (AE). She was recovered well and free of her symptom. This report emphasizes the isolated appendiceal endometriosis, which can cause right lower quadrant pain and mimick appendicitis.

On-demand Electrohydrodynamic Jetting of an Ethylene Glycol and Water Mixture&amp;#x2014;System of Controlled Picoliter Fluid Deposition

On-Demand Electro Spraying or Single Event Electrospraying (SEE) is a method to jet small amounts of fluid out of a nozzle with a relatively large diameter by switching on and off an electrical field between nozzle and substrate. The jet decomposes in many fl droplets, the total amount of volume deposited is up to 5 pl. A pipette is considered in which an electrode is mounted close to the exit of the nozzle. The electrode is connected to a high voltage power amplifier. By switching on the electrical field the apparent surface tension drops, the meniscus deforms into a cone and fluid starts to flow towards the nozzles. The moment the cone has reached the Taylor cone dimensions, from the tip of the cone a jet emerges and a number of charged fl droplets fly towards the substrate. This process stops when the pulse is switched off. After switching off the meniscus returns slowly to its equilibrium position. The process is controlled by different time constants, such as the slew rate of the power amplifier and the RC time of the electrical circuit composed of the electrical resistance in the fluid contained in the nozzle between electrode and meniscus, and the capacitance of the gap between the meniscus and the flat substrate. Another time constant deals with the fluid flow during the growth of the meniscus, directly after switching on the pulse. This fluid flow is driven by hydrostatic pressure and opposed by viscous drag in the nozzle. The final fluid flow during droplet formation is governed by the balance between by the drag of the charge carriers inside the fluid, caused by the current associated with the charged droplets leaving the meniscus and the viscous drag. These different phenomena will be discussed theoretically and compared to experimental results.

(Invited) Microfluidics Enabled Protein Fractionation and Soft Wearable Robots

Microfluidics is a science that deals with small amounts of fluids at the microscale. The confinement brings in many advantages such as reduced reagent consumption, shortened analysis time, increased throughput and potential for portable systems. These advantages and others make microfluidic systems ideal enabling platform technologies that can be applied in a wide range of applications spanning from material synthesis, life science research, drug screening and environmental monitoring. This presentation summarizes Ren’s work on microfluidics that is dedicated to protein fractionation and soft wearable robots towards well-being. Protein fractionation techniques will include a suite of techniques such as isoelectric focusing, free flow focusing and pH elution. The soft wearable robots enabled by microfluidics will start with a brief introduction of soft robots and follow up with the unique angle that Ren’s team took for developing inexpensive, comfortable daily wearable assistive robots. Its demonstration and validation towards patients suffering from arthritis will be provided and discussed.