This work investigates a high-isolation Orthogonal Printed Elliptical Slot Antenna (OPESA) array with Multiple Inputs and Multiple Outputs (MIMO). A unique composite Electromagnetic Band-Gap (EBG) structure consisting of a vertical six rings positioned between single element antennas were devised and investigated with the aim of reducing mutual interaction between antenna components. A distinct feeble electric field that could successfully inhibit the Mutual Coupling (MC) among the antenna components is easily produced by the suggested composite EBG construction. One type of decoupling constructions throughout the antenna growth was carefully examined at together the theoretical and physical levels in order to offer a clear representation of the suggested antenna array’s design concept and decoupling technique. The antenna array design process was cleverly separated into three stages. In order to verify the suggested decoupling idea, the array Scheme was constructed, assessed, and measured. Studying the antenna gain, radiation pattern, and reflection coefficient, it was found that the simulated and measured findings were very consistent. According to the models, the array has an extreme radiation efficiency of about 91%, a minor value of Envelope Correlation Coefficient (ECC < 1.8 × 10−4), and a maximal gain of 11.5 dBi. The electrical size, highest isolating grade and the recommended MIMO antenna’s 90 dB isolating bandwidth (BW) were assessed. The planned antenna has several appealing features that set it apart from previous similar designs. These features include a low design complexity, a great Diversity Gain rate (DG > 9.99 dB), the BW of the proposed antenna extends from 25 GHz to more than 40 GHz, an enormously great isolation level (about 90 dB), and compressed dimensions (51 mm × 30 × 1.6 mm). For verifying the recommended antenna for MIMO. the suggested MIMO antenna design’s radiation efficiency, a thorough time-domain study is suggested.