As the cross-section of the helical strand increases, the effect of its nonlinear bending characteristics becomes significant. To accurately simulate the response of helical strands under such conditions using the finite element method, determining the tangent bending stiffness of helical strands is indispensable. However, the approach of calculating the tangent bending stiffness of helical strands based on the stick-slip state of wires is not universally applicable across all strand models. In this study, we propose an approach for calculating the tangent bending stiffness of strands based on two mechanical models of helical strands. This proposed approach uses the ratio of the “actual increment” to the “theoretical maximum increment” of the nonlinear component of the wire axial force to calculate the contribution of one wire to the tangent bending stiffness of the strand. Significantly, this approach can be applied to different strand models, each of which may adopt different slip criteria. By comparing the results with the numerical solutions, we validate the effectiveness of the proposed approach for calculating the tangent bending stiffness of helical strands on different strand models. Furthermore, it is pointed out that the analytical results of wire sliding may vary significantly depending on the adopted slip criteria.