Abstract Background The Beneficial Parenting Partnership (BPP) model is being implemented in Parent-Infant Centers (PIC) across Israel to improve the partnership skills of PIC nurses when working with parents, promote child development, and enhance parental well-being. This initiative is being led by the Israeli Ministry of Health, Goshen NGO, and Lotem company and is supported by the Yad Hanadiv and Bernard van Lear foundations. Methods The first data collection (T1) was held from December 2022 to January 2023 among 706 parents of children aged two weeks to 36 months (M = 8.17 months, SD = 7.48) who visited one of 18 PICs. Research assistants approached the parents and asked for their agreement to fill in the study questionnaire. Of these, 328 parents agreed to participate in the follow-up study (T2) held in January-February 2024 using a telephone survey. Differences in the parent’s satisfaction, visit experience, and parental well-being were assessed using parried sample T-tests. A linear regression model was calculated to assess the factors predicting the increase in the parent’s visit satisfaction. Results Significant differences were measured between T1 and T2 in parental satisfaction (M = 4.51 and 4.71 retrospectively, P < 0.001), parental positive visit experience (M = 4.58 and 4.68 retrospectively, P = 0.019), and parental well-being (M = 3.81 and 3.97 retrospectively, P < 0.001). Findings suggest a marked improvement in satisfaction, visit experience, and reported well-being after a year of BPP model assimilation among PIC nurses. The regression model, explaining 42% of the variance in increased parental satisfaction, indicated that a higher increase could be predicted by a higher increase in positive visit experience and a higher trust level in the PIC nurse at T1. Conclusions The BPP model’s assimilation among Israeli PIC nurses was successful, resulting in improved parent experience, satisfaction, and well-being. Key messages • The Beneficial Parenting Partnership model is well-suited for implementation among nurses working with parents of babies and toddlers to promote collaborative nurse-parent communication. • During routine meetings at Parent-Infant Centers, nurses can act as a catalyst for promoting parental well-being.