Gas explosions mostly occur in turbulent environments in practical situations. Meanwhile, the current research on the explosion characteristics of hydrogen-doped natural gas is mostly methane/hydrogen mixed fuel, ignoring the influence of other components of natural gas on the explosion characteristics of the actual situation. Therefore, the effects of different jet intensities (Pjet), hydrogen-doping ratios (XH2) and equivalence ratios (φ) on the explosion characteristics of multi-component natural gas/hydrogen mixed fuel are experimentally investigated in cylindrical tanks of 30 L. Additionally, it extensively explored the dual influence of jet disturbance and gas inerting effect on the flame propagation characteristics of multi-component natural gas/hydrogen mixed fuel. With the increase of Pjet, both Pmax and (dp/dt)max initially increase and then decrease, while τ continuously decreases. When Pjet = 0.4 MPa, the promotion effect on Pmax and (dp/dt)max is most significant. The lifting of XH2 leads to a gradual increase in Pmax and decreasing τ. (dp/dt)max exhibits a trend of initially increasing and then decreasing with the elevation of XH2, reaching its maximum at XH2 = 40%. The introduction of jet flow significantly reduces the promotion or inhibition effect on explosions of high hydrogen blending ratio mixtures. Furthermore, the introduction of jet flow is more effective in promoting the explosive performance of multi-component natural gas/hydrogen mixed fuel with high equivalence ratios and low hydrogen doping ratios under rich fuel conditions. This study can provide a key reference for the explosion hazard assessment during the practical application of natural gas/hydrogen mixed fuel.