You have accessJournal of UrologyPediatrics: Congenital Anomalies - Kidney & Ureter1 Apr 2011446 CHARACTERIZATION OF SINGLE SYSTEM URETEROCELE IN ASSOCIATION WITH IPSILATERAL MULTICYSTIC DYSPLASIC KIDNEY Beth A. Drzewiecki, John C. Thomas, Stacy T. Tanaka, John C. Pope, Mark C. Adams, and John W. Brock Beth A. DrzewieckiBeth A. Drzewiecki Nashville, TN More articles by this author , John C. ThomasJohn C. Thomas Nashville, TN More articles by this author , Stacy T. TanakaStacy T. Tanaka Nashville, TN More articles by this author , John C. PopeJohn C. Pope Nashville, TN More articles by this author , Mark C. AdamsMark C. Adams Nashville, TN More articles by this author , and John W. BrockJohn W. Brock Nashville, TN More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.538AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Ureteroceles most commonly present in duplicated renal systems and are associated with the obstructed upper pole moiety. We report our experience with single system ureteroceles (SSU) in conjunction with ipsilateral multicystic dysplasic kidney (MCDK). METHODS We retrospectively reviewed the charts of all patients diagnosed with MCDK (ICD9 753.19) and ureterocele (ICD9 753.23) between January 1, 2000 and July 31, 2010 to identify children with SSU and MCDK. We excluded patients with dysplasia associated with posterior urethral valves (4), only one clinic visit (19), surgical pathology not consistent with MCDK (7), other diagnoses (9), and mothers seen for prenatal counseling (33). Gender, laterality, location, contralateral vesicoureteral reflux (VUR) and treatment were evaluated. Results were compared using Fisher exact probability test. RESULTS A total of 210 (54% male and 46% female) were included in the analysis. With the exception of 5 children, all were diagnosed prenatally with a presumed MCDK and confirmed post natally with ultrasound and/or renal scintography. Single system ureteroceles were identified in 21 children (10%), 19 males and 2 females. Male gender was significant for development of SSU (p<0.00). There was no difference in laterality between the two groups. Contralateral VUR was identified in 3 (14%) children with SSU compared to 34 (18%) in those with MCDK alone (p=0.8). Ureteroceles were classified as ectopic (10) and intravesical (11) based on cystoscopy and/or cystography. Treatment consisted of nephrectomy (16), transurethral incision (2) and observation (3). Indications for nephrectomy included large size of MCDK (5), reflux into system (2), ureterocele causing obstruction or significant distortion (6), and parental wishes (4). CONCLUSIONS MCDK may result from an improper union between the ureteric bud and metanephric blastema, however defects of the distal ureteric bud are under reported. Single system ureterocele in association with ipsilateral MCDK is rare, and are more predominant in males. Contralateral vesicoureteral reflux associated with MCDK is independent of ureterocele. Indications for surgery may vary, however observation remains a viable option for some patients. MCDK MCDK and SSU No. of patients 189(90%) 21(10%) Male 95(50%) 18(86%) Female 94(50%) 3(14%) Side Right 90(48%) 9(43%) Left 99(52%) 12(57%) Contralateral anomaly VUR 34(18%) 3(14%) UPJ 4(2.1%) 0(0%) © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e181-e182 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Beth A. Drzewiecki Nashville, TN More articles by this author John C. Thomas Nashville, TN More articles by this author Stacy T. Tanaka Nashville, TN More articles by this author John C. Pope Nashville, TN More articles by this author Mark C. Adams Nashville, TN More articles by this author John W. Brock Nashville, TN More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
Read full abstract