Ecofriendly soybean coolant offers a sustainable alternative to conventional coolants, providing excellent thermal performance while reducing environmental impact. Its biodegradable nature and low toxicity make it a safe choice for various cooling applications, promoting greener industrial practices. This study investigates the thermal performance of eco-friendly soybean nanofluids dispersed with alumina and molybdenum disulfide (MoS2) nanoparticles for cooling a titanium alloy block. The investigations are conducted using single and dual nozzle setup to assess the impact of nanoparticle shape, volume fraction and Reynolds number on heat transfer characteristics of ecofriendy coolant. The discretization is conducted using the finite volume method, and the Nusselt number is calculated from the convective heat transfer coefficient. Results show that platelet-shaped nanoparticles exhibit superior thermal conductivity and heat transfer performance compared to spherical and cylindrical shapes. Increasing the volume fraction of MoS2 platelet-shaped nanoparticles from 0.5% to 6% results in a reduction of the average temperature distribution of the titanium block by 26.53% in the single-nozzle setup and 28.87% in the dual-nozzle configuration. The dual nozzle arrangements significantly enhance heat dissipation, with MoS2 nanoparticles decreasing the temperature distribution by 9.24% in the single-nozzle setup and 15.78% in the dual-nozzle setup compared to alumina nanoparticles. Optimal thermal performance is observed at elevated Reynolds numbers, where platelet-shaped MoS2 nanoparticles achieve the highest Nusselt numbers. Specifically, incorporating MoS2 cylindrical-shaped nanoparticles into soybean oil at higher Reynolds numbers improves average heat transfer by up to 29.16% when compared to cylindrical alumina nanoparticles. The enhancements in heat transfer for spherical and platelet-shaped MoS2 nanoparticles are 37.51% and 46.66%, respectively, relative to cylindrical alumina particles. This research offers crucial guidance on developing and enhancing sustainable coolants, revealing the significance of nanoparticle shape in optimizing thermal performance and paving the way for cleaner production processes that prioritize environmental responsibility.