The DC–DC converters have been used extensively in various industrial applications such as consumer electronics, aerospace, electric vehicles, and renewable energy systems. The reliability ensures that the converter continues to operate safely and efficiently despite the presence of faults. Enhancing the reliability of DC-DC converters is a challenging task, as power switches are the most fragile components that can be affected by faults in the system. Hence, to address these challenges and ensure the safety of the converter, it is vital to implement appropriate fast fault-diagnosis techniques and fault-tolerant strategies. Many new network topologies have been presented in literature, which lead to a shift from single input–single output to multiport converters. These converters are suitable for integrating different energy sources. However, the majority of them are operated using a time-sharing method, in which only one energy source is used at a time, and the others are inactive at any specified duty cycle. Therefore, the converter and input sources are underutilized in the conventional time-sharing approach. This paper proposes a new multi-input single-output (MISO) converter topology with fully integrated switch fault tolerance. It can perform multi-input buck, boost, and buck-boost operations. More importantly, the converter can operate uninterruptedly for single or multiple switch faults. Using simulation and experimental results, a 400 W prototype circuit is designed to analyze the converter's reliability and performance.