AbstractFiber optic sensors (FOS) in long-term structural health monitoring (SHM) have drawn significant attention due to their pivotal role in detecting defects and measuring structural performance in diverse infrastructures. While using FOS, temperature variation due to environmental factors is still considered one of the major challenges to isolating sensing parameters. To address this issue, we reported a machine learning (ML)-augmented multi-parameter sensing system that enables simultaneous detection of strain and temperature effects based on one single fiber Bragg gratings (FBGs) sensor for SHM. The initial phase entailed designing, fabricating, and characterizing a novel FBG sensor in the laboratory, incorporating a set of four FBGs, each distinguished by distinct Bragg wavelengths. In the next phase, ML algorithms are employed to separate temperature effects from strain variations. As a proof of concept, mechanical loading tests are conducted on the sensor, exposing the FBG portion to various temperature conditions. In the final phase, data collected from a post-tensioned concrete bridge embedded with both strain and temperature FBG sensors are utilized, and the developed ML models are applied to observe real-environment outcomes. Despite the limited feature points of collected FBG spectrums, the developed ML models effectively address cross-sensitivity issues induced by temperature perturbations. The long-term benefit of using FOS is that it will enable a better understanding and utilization of aging infrastructure. This will potentially reduce embodied carbon of infrastructure in the future and assist in the global efforts to achieve Net-Zero.