A new voltage-mode universal filter using five single-ended operational transconductance amplifiers (OTAs) with two grounded capacitors and a quadrature oscillator using the proposed voltage-mode universal filter is presented in this paper. The proposed circuit can provide non-inverting lowpass, bandpass, highpass, bandreject and allpass filters, and inverting bandpass and highpass filters by appropriately applying different five input voltage signals. The circuit only employs five single-ended OTAs with two grounded capacitors to maintain the following advantages: (i) orthogonal electronic tunable resonance angular frequency and quality factor without control factor matching conditions, (ii) no resistors required, (iii) high-input impedance, (iv) no extra inverting or non-inverting amplifiers for special input signals, and (v) low active and passive sensitivities. Besides, the proposed filter can be used to implement a quadrature sinusoidal oscillator with independently controlled oscillation condition and the oscillation frequency. OrCAD PSpice simulation and experimental results of commercially available OTAs, LT1228, are used to confirm the characteristics of the proposed voltage-mode universal filter and quadrature sinusoidal oscillator.