The environment of the Tibetan Plateau (TP) is extremely sensitive to global climate change, and the frequent aeolian activity on the central TP generates large amounts of dust with the result that the region has a major impact on regional and global environmental change. The extensive aeolian dunes on the central TP provide a direct and valuable archive of aeolian activity; however, the age and sediment deposition processes of these dunes are still poorly understood. Optically stimulated luminescence (OSL) dating, an effective method for dating aeolian sediments, has been used sparingly in the region. In this study, we applied quartz single-aliquot regenerative-dose (SAR) OSL, K-feldspar post-infrared infrared-stimulated luminescence (pIRIR), and single-grain K-feldspar pIRIR methods to determine the ages of two well-preserved sand dunes in the Lunpola (LD) and Tuotuohe (TTH) river basins in the central TP. Our results showed that the quartz OSL signal of the TTH dune was dim, while the LD dune quartz exhibited a higher OSL sensitivity than that of the TTH dune. The high recuperation observed could be attributed to the low signal-to-noise ratio of the OSL signals. The K-feldspar signal was bright and the pIR50IR170 signal could be used to date young dune samples in the central TP, whereas it could be affected by the residual dose, or incomplete bleaching in the TTH profile, resulting in age overestimation. The single-grain K-feldspar protocol had a good potential for dating the young TP dunes. Multi-method luminescence dating is recommended for the cross-checking of young dune samples with low OSL sensitivity in the TP. Our luminescence dating reveals that aeolian dunes in the central TP formed approximately 385 to 330 a and persisted to the present, possibly in response to climate change since the late stage of Little Ice Age (1400−1850 CE).