Rapid analysis of health hazardous materials is necessary to prevent foodborne illness in food control science. Bisphenol A (BPA) is one of the potentially hazardous materials that may potentially create adverse health effects, if its concentration level in food is not controlled. In this work, carbon paste electrode has been modified with CdO nanoparticles and ionic liquid (IL/CdO/CPE) for determination of BPA in food samples. In addition, vitamin B6 (B6) has separated oxidation peak at modified electrode and simultaneous determination of BPA and B6 is possible. The square wave voltammetric peak currents of BPA and B6 at IL/CdO/CPE have linear relation to their concentrations in the range of 0.01 to 800 μmol L−1 BPA and 0.4 to 500 μmol L−1 B6. Selectivity of the modified electrode was studied, and it was successfully applied for analysis of food samples.