Simulated Moving Bed Process For Separation Research Articles

Parametric uncertainties and influence of the dead volume representation in modelling simulated moving bed separation processes

In this study, a systematic numerical procedure for identifying the model parameters of simulated moving bed (SMB) separation processes is developed. The parameters are first estimated by minimizing a weighted least-squares criterion using experimental data from batch experiments, e.g. the time evolution of the concentration of elution peaks. Then, a cross-validation is achieved using data from experiments in SMB operation. At this stage, the importance of a careful modelling of the dead volumes within the SMB process is highlighted. In addition, confidence intervals on the estimated parameters and on the predicted concentration profiles are evaluated.

Parabolic intraparticle concentration profile assumption in modeling and simulation of nonlinear simulated moving-bed separation processes

This communication will focus on the application of the LDF (Linear Driving Force) mass transfer model in the mathematical simulation moving-bed separation processes with nonlinear adsorption isotherms to compare with the linear pore diffusion model, in order to determine its validity as well as to establish the equivalence between the two models.