Abstract An interesting field of studying nonlinear systems is their sensitivity study. With sensitivity study the most influential parameters on a system can be obtained and then the simplification and improvement of the model will be possible. In this paper the global sensitivity study of a Duffing-type vibration system is carried out with Sobol’s variance-based method taking the root mean square of acceleration and the maximum acceleration as output variables. With the sensitivity study it was observed that the parameters of the excitation signal like the amplitude and the angular velocity are the most influential. It was also found that a single parameter has less influence on the system than the parameter combinations. The aim of the research is to carry out the global sensitivity study of a relatively simple nonlinear system. The study is the basis for further research tasks in order to perform the sensitivity study of more complex systems.