In the spring of 2001, the upgraded Fermilab Tevatron will begin its collider physics run with [Formula: see text] collisions at [Formula: see text], where it is expected to deliver an integrated luminosity of 2 fb -1 in the first two years. The DØ detector is undergoing an extensive upgrade in order to take full advantage of the high luminosity running conditions. The upgraded detector's new silicon vertex detector, fiber tracker, and lepton trigger capabilities make a rich B physics program possible at DØ. This paper describes the prospects for several DØ B physics measurements, including CP violation in [Formula: see text] decays, Bs mixing and [Formula: see text] lifetime.