Significant Negative Correlation Research Articles

Supportive care needs and anxious-depressive symptoms in cancer patients: An interaction effect between emotional competence and the COVID-19 pandemic?

The main objective was to assess the link between emotional competence (EC) and adjustment outcomes such as supportive care needs (SCN) and anxious-depressive symptoms in cancer patients starting chemotherapy. The second objective was to assess the interaction effect between EC and the COVID-19 pandemic (i.e. patients included before or during the pandemic) on these outcomes. At the beginning of care, 255 patients with digestive or hematological cancer, recruited before the pandemic began (n = 156, 61.2%) or during the pandemic (n = 99, 38.8%), completed the Short Profile of Emotional Competence, the Hospital Anxiety and Depression Scale, and the Supportive Care Needs Survey Short Form. Partial correlations and multiple regressions were used. Intrapersonal EC showed negative significant correlations with psychological unmet SCN (r = -.32, p < .001), anxiety (r = -.37, p < .001), and depression (r = -.46, p < .001). Interpersonal EC showed only significant interaction effects (p < .05): it was only associated with fewer unmet physical and daily SCN (p < .002) and fewer depressive symptoms (p < .004) during pandemic. Results show significant associations between intrapersonal EC and better adjustment of cancer patients from the early stage of care. Interpersonal EC seems to be a significant resource to deal with illness only in difficult contexts such as the COVID-19 pandemic.

Pistia Stratiotes based heavy metals phytoremediation of a Himalayan river impacted by hydroelectric plant in an Indo Burma hotspot region

ABSTRACT Present study attempts to study the impact of Serlui-B hydroelectric dam on water quality (‘water-energy nexus’) of a Himalayan river and to devise possible phytotechnology for heavy metals remediation. Physico-chemical characteristics of water were analyzed using ‘American Public Health Association (APHA)’ methods while Atomic Absorption Spectrophotometer (AAS) was used for estimation of heavy metals. To this end, concentrations of Fe and Ni were recorded above permissible limit which can impose public health risks. Therefore, phytoremediation experiments were performed by using Pistia stratiotes L. (water lettuce) and effects of Fe and Ni concentrations (1.0, 2.0, and 5.0 mg/L) on photosynthetic pigments were observed. Phytoremediation investigations using 24 aquaria (of 40.5 L) revealed that P. stratiotes was an effective hyperaccumulator of Fe and Ni with maximum removal efficiency of 96.2% and 92%, respectively. In relation to bioaccumulation indices, the bioconcentration factor (BCF) values decreased with increase in Fe and Ni concentrations, whereas the translocation factor (TF) was noted higher at low concentrations and vice versa. Furthermore, the total chlorophyll content and carotenoid levels in P. stratiotes demonstrated negative significant correlation with the rise in Fe/Ni concentrations that may be considered as an adaptive biochemical strategy to mitigate metals induced oxidative stress. The present study can further be extrapolated to field phytoremediation for ameliorating both physico-chemical and metallic contaminants. Last, the role of microbial biodiversity associated with P. stratiotes should be elucidated in future to help achieve SDG 6 and environmental sustainability.

The Relationship between Neutrophil-Lymphocyte Ratios with Nutritional Status, Risk of Nutritional Indices, Prognostic Nutritional Indices and Morbidity in Patients with Ischemic Stroke.

Background: In recent years, whole blood parameters and derivatives have been used as prognostic criteria in the course of various diseases. The aim of this study was to evaluate the relationship between parameters such as the neutrophil-lymphocyte ratio (NLR), the systemic immune-inflammation index (SII), the prognostic nutritional index (PNI), controlling nutritional status (CONUT) score, nutritional risk index (NRI) and immunonutrition status and disease activity in patients with ischemic stroke of the small-vessel, large-vessel and other etiologies. Methods: We retrospectively evaluated the records of 1454 consecutive ischemic stroke patients hospitalized in the emergency department of Gaziosmanpasa Education and Research Hospital from 2019 to 2023. Results: Of the 1350 patients with ischemic stroke included in the study, 58.8% had small-vessel disease, 29.3% had large-vessel disease and 11.9% had other etiologies. There was a significant difference between the three etiology groups for PNI and CONUT. The mean of PNI was 47.30 ± 8.06 in the other etiology group, 37.25 ± 7.23 in the small-vessel group, and 34.78 ± 8.16 in the large-vessel disease group. The mean of CONUT was 5.49 ± 1.20 in the small-vessel group, 5.12 ± 1.46 in the large-vessel group and 4.22 ± 1.11 in the other etiology group. In addition, CONUT and PNI were also found to be independent risk factors for mortality. A negative significant correlation was observed between PNI and NLR (r: -0.692), SII (r: -0.591), and CONUT (r: -0.511). Significant correlations were observed between CONUT and NLR (r: 0.402), SII (r: 0.312). Conclusions: PNI, CONUT and NRI were found as more accurate prognostic indicators of nutritional status in patients with ischemic stroke. NLR and SII may be important predictive markers in the course and prognosis of stroke.

Level of interleukin 17 in inflammatory bowel disease and its relation with disease activity

BackgroundInflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder of the gastrointestinal tract (GIT).It results in progressive intestinal epithelium structural and functional damage that necessitates lifetime medication.Thereis imbalance in the production of T helper 1 (Th1), Th2 and Th17 cytokines. This plays a crucial role in the chronic inflammatory process and the defective immune response to pathogenic agents; thus promoting the recurrence of the disease.Our aim of this study was to detect serum IL-17 levels in IBD patients and its relation with disease activity.MethodsThis was a single center case control study, conducted at hepatology and gastroenterology unit, Mansoura specialized Medical Hospital, Egypt.Patients who were included were aged 18–65 years, diagnosed either Ulcerative Colitis (UC)or Crohn’s Disease (CD) based on previous colonoscopy.IBD activity was measured for UC using the MAYO score and CD using the CD activity index (CDAI). Fifty five patients were UC, 24 patients were CD, 21 patients were control.Patients who were excluded were under 15 years old, with history of GIT malignancy, or any serious comorbidities. Study protocol was approved by Institution Research Board (IRB) of Mansoura Medical College.All patients were subjected to full history taking, routine physical examination, colonoscopy and laboratory investigations including serum IL-17 levels by ELISA besides CBC, CRP, ESR and fecal calprotectin.ResultsSerum IL-17 level was increased significantly among UC; median (min-max) = 72(21–502)pg/ml, in CD 54.5(25–260) versus control 19 (14–35), P < 0.001.However, it was not correlated to the disease activity either Mayo score of UC or CDAI of CD.There was significant correlation to the extent of inflammation in UC affecting the colon (either proctosigmoiditis, left sided colitis or pan colitis), also to the type of CD (either inflammatory, stricturing or fistulizing) by P < 0.05.It was not correlated significantly with any of the IBD activity markers (CRP, ESR, or fecal calprotectin).Yet there was negative significant correlation with Hb level (r =-0.28, p = 0.005).There was not significant association between median serum level of IL-17 & duration of disease (P = 0.6).However, median IL-17 was higher among hospitalized cases than non-hospitalized (73 & 55, pg/ml respectively; p < 0.002). AUC was significantly differentiating between IBD and control group = 0.993 with the best-detected cut off point from curve 32 pg/ml yielding sensitivity of 97.5% and specificity of 95.2%.ConclusionSerum IL-17 increases in colonic inflammation significantly more than in control group, however its increase is not correlated to IBD activity.

School burnout in adolescents: what are the roles of emotional autonomy and setting life goals?

ABSTRACT This study was conducted to investigate the mediating role of setting life goals in the relationship between emotional autonomy and school burnout. The mediation model was tested on 304 high school students [156 (51.3%) females, 148 (48.7%) males; Mage = 16.12, SD = 1.20]. According to the results, we found that school burnout had negative significant correlations with emotional autonomy and setting life goals. On the other hand, there was a significant positive correlation between emotional autonomy and setting life goals. The analysis results indicated that setting life goals had a mediating role between emotional autonomy and school burnout. Accordingly, emotional autonomy promoted setting life goals and contributed to mitigating school burnout. In this respect, this study points out that some positive emotional factors have a protective function against school burnout.

Prognostic Significance of Lymph Node Ratio in Predicting the Outcome of Oral Squamous Cell Carcinoma – A Retrospective Study

Abstract Introduction: The lymph node status is a very important prognostic factor in head-and-neck cancer. The presence of metastatic lymph nodes will reduce the overall survival by 50%. Lymph node ratio (LNR) is defined as the ratio of the number of positive lymph nodes to the total number of lymph nodes dissected. The aim of the study was to investigate the prognostic value of LNR in oral squamous cell carcinoma (OSCC). Materials and Methods: Medical records of pathologically confirmed OSCC patients who reported with loco-regional recurrence from January 2017 to January 2022 were analysed. LNR and disease-free survival (DFS) were calculated for each patient. The endpoint of the study was disease-free survival. Spearman’s correlation was used to establish a correlation between DFS and LNR. Results: A total of 33 patients were included in the study. DFS was calculated for all the patients. LNR was calculated in patients with pathological N+ neck. There was a negative significant moderate correlation between LNR and DFS (Spearman’s rho = −0.593, P &lt; 0.001). A higher LNR value of more than 0.01 was associated with a shorter DFS period. T4 tumour stage had significantly higher LNR. A positive significant moderate correlation was found between LNR and tumour stage (Spearman’s rho = 0.703, P = 0.01). As the T stage increased, the LNR ratio also increased. In the present study, tumour subsite tongue was associated with significantly higher LNR (P = 0.001). Discussion: LNR can be considered an independent prognostic parameter for DFS in OSCC patients with cervical lymph node metastasis.

Evaluation of Common Bean (&amp;lt;i&amp;gt;Phaseolus vulgaris &amp;lt;/i&amp;gt;L) Cultivars for Yield and Yield-Related Traits at Sekoru District, South Western Ethiopia

The low productivity of common beans is attached to many yield constraints such as lack of improved varieties; poor management practices, biotic and abiotic factors. This study was conducted to evaluate the performance of improved common bean varieties for yield and yield related traits in the Sekoru district of the Jimma zone and identify high-yielding varieties for the study area. Eleven released and one local common bean variety were tested in two locations (Yero Sekoru and Inkure), using a randomized complete block design with three replications. Data were collected for 12 quantitative traits and subjected to analysis using SAS software. The interaction effect of genotype by location showed a highly significant variation for all traits except for plant height, dry biomass yield, and hundred seed weight. The phenotypic coefficient of variation was higher than the genotypic coefficient of variation for all traits. Higher The phenotypic coefficient of variation was recorded for 100 seed weight (52.78), pod length (28.9), pods per plant (27.63), harvest index (25.94) and seed yield (24.6) and also a high genotypic coefficient of variance (GCV) was observed for 100 seed weight (20.24) and pods per plant (20.34). Low (20) and high (93.5) heritability in broad sense were recorded in days to 50% flowering and dry biomass yield, respectively. At the phenotypic level, all traits had a positive phenotypic significant correlation with seed yield per hectare except for primary branches per plant day to 95% physiological maturity and hundred seed weight, while a negative significant correlation with seed yield per hectare was observed for days to 50% flowering. Genotypic path coefficient analysis indicates that the traits studied showed a positive direct effect on seed yield per hectare, while plant height, primary branches and secondary branches per plant, days to 50% flowering, days to 95% physiological maturity and 100 seed weight exhibited a negative direct effect. However, a positive direct phenotypic effect was observed for traits such as dry biomass yield, pod length, primary branches per plant, seeds per pod, and days to 95% physiological maturity. Among the varieties tested in both locations, the highest yield was recorded for the Ser119 variety (2865.2 kg/ha) followed by the Ser125 variety (2699.2 kg/ha). Therefore, recommending these varieties to farmers in the study area is very important to increase production and income.

Assessment of Oral Hygiene and Gingival Health Condition and their Relationship with Some Salivary Variables among Boxers

Background: Background oral hygiene means the degree of cleanliness of the oral cavity. Good oral hygiene is necessary to prevent common oral diseases. Objectives: to evaluate the relation of some salivary variables to oral hygiene and gingival health conditions among Iraqi boxers. Subjects and Methods: There was a cross-sectional comparative study. The total sample consisted of 80 males, including 40 male boxing players with weights ranging from (46-60 kg) attending different sports clubs for boxers in Baghdad (study group). And 40 male school students from some schools in Baghdad (comparative groups), ages ranging from (15-16) years old. This study was conducted from January-2022 to the end of May -2022. The unstimulated salivary analysis included samples collected flow rate, pH, and Minerals (calcium and phosphate) and salivary immunoglobulin A. After that, the clinical Assessment of gingival disease, calculus and plaque were assessed. Results: The results demonstrate that plaque and calculus are higher in the study group than in the control with a significant difference in plaque index and no significant difference in calculus. Concerning correlations, a weak negative significant correlation between flow rate and plaque index in control weakens the negative significance between Gingival index and PH, while other results are insignificant. Also, Findings show a weak negative significant correlation between plaque index and salivary IgA and a weak negative significant correlation between Gingival index and calcium and phosphorous in control. Conclusions: In conclusion, boxer players were associated with high gingival index, calculus and plaque index compared to control groups.  

Dietary Adherence in Children with Amino Acid Metabolism Disorders and its Impact on Caregivers’ Quality of Life

This study explored the relationship among socio-demographic factors, patients’ dietary adherence, and the Quality of Life (QoL) experienced by their caregivers. A cross-sectional study was carried out, involving 66 caregivers of pediatric patients in Malaysia diagnosed Amino Acid Metabolism Disorders (AAMDs). Dietary adherence was assessed using a modified version of the Malaysia Medication Adherence Assessment Tool (MyMAAT-12), and the caregiver’s QoL was evaluated using the 36-Item Short Form Survey (SF 36) questionnaire. Majority of the patients were Malay (75.76%), and female (59.1%). Statistical analysis found that caregivers with a higher education level were associated with a higher dietary adherence (rs (64)=0.382, p=0.002) and better mental health (rs (64)=0.281, p=0.022). The age of patients had negative significant correlation with the physical function and general health (rs (64)=0.287, p=0.019) of their caregivers. Besides that, dietary adherence was negatively correlated with social functioning (p=0.010), role limited due to physical health (p=0.018), role limited due to emotional problems (p=0.022), vitality (p=0.021), mental health (p=0.014) and pain (p=0.011). Conclusion: Dietary adherence had a significant impact on the QoL for caregivers of patients with amino acid metabolism disorders. Therefore, it is crucial to explore appropriate treatment strategies and provide support to enhance patients' adherence to their dietary requirements, simultaneously improving the caregivers' QoL.

Examining Factors Influencing Length of Stay for Inpatients at Alcohol and Substance Addiction Treatment Center

Objective: The aim of this study is to determine the impact of impulsivity, treatment motivation, anxiety, and cognitive distortions on the duration of inpatient treatment for substance use.&#x0D; Methods: The sample for the study consisted of 200 volunteer patients receiving inpatient treatment at the Alcohol and Substance Addiction Treatment Center. Participants underwent a general psychopathological evaluation using the Structured Clinical Interview for DSM-5 (SCID-5) administered by the clinician. All participants were given the Case Report Form prepared by the clinician along with the Barratt Impulsivity Scale-11 Short Form (BIS), Automatic Thoughts Scale (ATS), State and Trait Anxiety Inventory (STAI-I, STAI-II) and Treatment Motivation Questionnaire (TMQ).&#x0D; Results: A significant distinction was noted in discharge statuses when comparing scores on the Barratt Impulsiveness Scale and nonplaning impulsiveness subscale, and the State and Trait Anxiety Inventory and Automatic Thoughts Scale. Those who were discharged with remission had notably lower scores compared to those who left voluntarily or were discharged due to rule violation (p&lt; 0.001). Negative significant correlations were found between length of stay and Barratt Impulsiveness Scale and its subscales [BIS-T (p

Factors Related to Maternal-fetal Attachment in Pregnant Mothers: An Analytical Cross-sectional Study

Aim:: The study investigated the relationship between Determining the Factors Related to Maternal-Fetal Attachment in Pregnant Mothers with Maternal-Fetal Attachment. Background:: Demographic policies in Iran emphasize population, fertility, and maternal health. Maternal-fetal attachment (MFA) is a term used to describe conditions that help the mother cope with the physiological changes during pregnancy. MFA contributes significantly to the future health of mother and child. Thus, it is essential to identify the nature of maternal-fetal attachment during pregnancy, when women need to prepare for and adapt to childbirth. The present study was conducted to determine the factors related to maternal-fetal attachment in pregnant mothers of Arak City. Objectives:: The study investigated the relationship between obstetric-demographic factors, emotional intelligence, marital satisfaction, and domestic violence with maternal-fetal attachment. Methods:: The present cross-sectional study was conducted on 177 pregnant mothers with a gestational age of 37-40 who were referred to health centers in Arak, Iran, for pregnancy care in 2022. Five questionnaires, including an obstetric-demographic questionnaire, Cranley's Standard Mother-Fetal Attachment Scale, Schutte Self-Report Emotional Intelligence Test, ENRICH marital satisfaction scale, and HITS domestic violence questionnaire, were used to measure the factors related to maternal-fetal attachment. Data were analyzed using SPSS21 software and descriptive and analytical statistics, including frequency distribution, Pearson correlation, t-test, Chi-square, Analysis of variance (ANOVA), and Multiple Logistic Regression model. Results:: The mean of age women and age of husbands was 29.07± 5.88 years and 32.93± 5.28 years, respectively. The mean maternal-fetal attachment score was 88.12± 15.76. The mean of the emotional intelligence, the marital satisfaction and, the domestic violence was 4.71± 2.81, 121.88± 17.30, 37.86± 7.25, 6.54± 3.35, respectively. The interval between the current and the previous pregnancy had a range of 1-7 years and a mean of 4.71± 2.8 years. There was a positive significant correlation between the maternal-fetal attachment score and the interval between the current and the previous pregnancy (r=0.22, p=0.02), There was a positive significant correlation between the maternal-fetal attachment score and the emotional intelligence (r=0.31, p=0.001) the marital satisfaction (r=0.25, P=0.001). There was a negative significant correlation between the maternal-fetal attachment score and the domestic violence (r=-0.26, p=0.001 Conclusion:: Identifying attachment-related factors helps the health staff carry out the necessary training and preventive measures to increase maternal-fetal attachment, especially in high-risk parents who need more care.

Gastritis and peptic ulcers are associated with the lower levels of plasma lipids: possible involvement of histamine

Background: Histamine receptors are involved to regulate lipid metabolism, so the hypothesis will arise that pathological states with abnormal histamine levels are associated with altered plasma lipids. Objectives: To study the profile of plasma lipids in patients with gastritis and peptic ulcer (GPU). Methods: In a case-control study, 70 dyspeptic patients were selected according to clinical criteria and using gastroduodenoscopy and compared with sex and age matched normal subjects. Results: There were no significant differences in age, sex, and the prevalence of hypertension and diabetes between two groups. But allergy, the familial history of allergy and dyspeptic and H. pylori infection were more prevalent in case group compared with controls. The levels of the indices of inflammation and body hydration were the same in two groups. Patients with dyspeptic compared with the controls had the lower concentrations of serum triglyceride (139.2±44.3 vs. 153.4±91.3), p≤0.553), total cholesterol (174.6±32.4 vs. 192.8±52.0, p≤0.073, LDLc (93.4±20.2 vs. 105.4±32.2, p≤0.015) and NonHDLc (130.2±38.1 vs. 159.2±42.2, p≤0.008). The level of HDL had not a significant change (43.4±7.8 vs. 43.5±12.7, p≤0.930). Dyspeptic state had negative significant correlation with total cholesterol, LDLc and NonHDLc but not HDLc. Neither the markers of inflammation nor the indices of body hydration had significant correlation with GPU. Conclusions: The GPU patients relative to normal group had the lower levels of serum lipids. The hypolipemic effects may be attributed to increased level of histamine in GPU patients.

Evaluation of the relationship between oral glucose tolerance test, blood sugar levels and cholesterol levels in prediabetic individuals

Objective: This study aimed to investigate whether there is a difference in lipid levels between prediabetic individuals with one-hour post-Oral Glucose Tolerance Test (OGTT) plasma glucose (PG) values &gt; 155 mg/dl and those with one-hour PG values ≤ 155 mg/dl.&#x0D; Methods: This retrospective cross sectional study was initiated on August 2020 and concluded on June 2021, and conducted with 229 prediabetic patients who presented to the Diabetes Clinic of the Research Hospital. A correlation analysis was performed to investigate the relationship between OGTT values and serum lipid levels. Additionally, the patients were divided into two groups based on the one-hour post-OGTT PG value of 155 mg/dl, and the presence of any difference in serum lipid levels between the two groups was examined using the Mann-Whitney U test. The SPSS 20 software was used for statistical analysis, and a statistical significance level of P &lt; 0.05 was considered.&#x0D; Results: Out of the 229 prediabetic patients included in the study, 172 were female. The number of patients with one-hour post-OGTT PG ≤ 155 mg/dl was 86, while those with values &gt; 155 mg/dl were 143. A statistically significant difference was found between the group with one-hour post-OGTT PG &gt; 155 mg/dl and the group with ≤ 155 mg/dl in terms of high-density lipoprotein (HDL-C) and triglyceride (TG) levels. There was a statistically significant negative correlation between one-hour PG and HDL-C.&#x0D; Conclusion: The evaluation of HDL-C and TG levels is important in prediabetic patients with a one-hour OGTT PG level greater than 155 mg/dL. &#x0D; doi: https://doi.org/10.12669/pjms.40.5.8292&#x0D; How to cite this: Oduncu EA, Tural E, Dayan A. Evaluation of the relationship between oral glucose tolerance test, blood sugar levels and cholesterol levels in prediabetic individuals. Pak J Med Sci. 2024;40(5):---------. doi: https://doi.org/10.12669/pjms.40.5.8292&#x0D; This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Evaluation of the Effect of Compassion Fatigue on Medical Error Tendency in Intensive Care Nurses

Objective: This study was conducted to evaluate the relationship between compassion fatigue and tendency to medical errors in critical care nurses.&#x0D; Methods: This descriptive study was conducted in the intensive care units of 16 hospitals (n=420) belonging to a private health group in Turkey between December 2021 and March 2022. Data were collected using the Compassion Fatigue-Short Scale and the Tendency to Medical Error in Nursing Scale (r=-0.252). &#x0D; Results: The nurses’ mean score on the Compassion Fatigue-Short Scale was 56.20±26.77 and their mean score on the Tendency to Medical Error in Nursing Scale was 4.82±0.28. There was a statistically significant negative correlation between total scale scores.&#x0D; Conclusions: The results suggest that the nurses in this study had moderate compassion fatigue and a low tendency to medical errors. A weak relationship was observed between higher compassion fatigue and a greater tendency to medical errors. Determining the factors that cause nurses to make medical errors is crucial to enable the necessary precautions to be taken. We recommend conducting multidimensional studies to evaluate the effects of compassion fatigue on patient safety and nursing outcomes.

Evaluation of hematological parameters and lipid profile in dyspeptic patient with gastric Helicobacter pylori infection, southern Ethiopia, 2022 GC

IntroductionHelicobacter pylori is gram-negative bacteria that mainly inhabits the human stomach and is one of the causes of dyspepsia. However, it is not confined to gastrointestinal tract and extends its pathogenesis on other system. PurposeTo evaluate lipid profiles and hematologic markers in dyspeptic individuals with and without H. pylori infection. Patients and methodsThe comparative cross-sectional study was conducted at Arba Minch General Hospital, from February 2022 to July 2022, 51 ​H. Pylori positive and 51 ​H. pylori-negative dyspeptic patients were recruited for this study by a non-probability purposive sampling technique. Using a pretested questionnaire, socio-demographic and behavioral variables were gathered. H. pylori antigen was detected in human fecal samples using the H. pylori Ag cassette for infection diagnosis. Blood samples were taken to evaluate lipid profile and hematological markers. SPSS version 21 was used to analyze the data and a P-value of <0.05 was regarded as statistically significant for all variables. ResultsThe study's findings revealed that the H. pylori-positive and H. pylori-negative study groups had different mean deviations for hematological parameters (Hg, RBC, HCT, MCV, MCH, and RDW) and lipid profiles. In the H. Pylori positive group compared to H. pylori-negative patients, the mean value of RDW (13.98 ​± ​0.96 vs. 14.96 ​± ​1.38) increased whereas other hematological profiles declined. When compared to H. pylori-negative dyspeptic individuals, there was a drop in the mean value of HDL (40.92 ​± ​5.64 vs. 37.65 ​± ​5.88) and increased the mean values of TC, TG, and LDL in H. pylori-positive patients. HDL showed a positive significant relationship with Hgb, RBC, and HCT r ​= ​0.39,r ​= ​0.38,r ​= ​0.43, respectively, while other lipid profiles (TC, TG, LDL) showed a negative significant correlation. ConclusionThe findings showed that H. pylori infection is related to altered lipid profiles and hematological markers, and HDL showed significant positive correlation with Hgb, RBC, and HCT.

Rice varietal resistance to the vector Sogatella furcifera hinders transmission of Southern rice black-streaked dwarf virus.

The Southern rice black-streaked dwarf virus (SRBSDV) transmitted by Sogatella furcifera constitutes a threat to sustainable rice production. However, most rice varieties are highly vulnerable to SRBSDV, whereas the occurrence of the viral disease varies significantly under field conditions. This study aimed to evaluate the potential of rice varietal resistance to S. furcifera in reducing SRBSDV transmission. Among the five rice varieties, Zhongzheyou8 and Deyou108 exhibited high resistance to S. furcifera, Baixiangnuo33 was susceptible, and TN1 and Diantun502 were highly susceptible. The S. furcifera generally showed non-preference for and low feeding on the Zhongzheyou8 and Deyou108 plants, which may explain the resistance of these varieties to S. furcifera. Transmission of SRBSDV by S. furcifera was significantly impaired on the resistant varieties, both inoculation and acquisition rates were much lower on Zhongzheyou8 than on TN1. The short durations of S. furcifera salivation and phloem-related activities and the low S. furcifera feeding amount may explain the reduced SRBSDV inoculation and acquisition rates associated with Zhongzheyou8. Spearman's rank correlation revealed a significant negative correlation between S. furcifera resistance and SRBSDV transmission among the tested varieties. The results indicate that rice varietal resistance to the vector S. furcifera hinders SRBSDV transmission, which is largely associated with the host plant selection and feeding behaviors of the vector. The current findings shed light on the management of the SRBSDV viral disease through incorporation of S. furcifera resistant rice varieties in the management protocol. © 2024 Society of Chemical Industry.

Emotion recognition and social functioning in individuals with autism spectrum condition and intellectual disability.

Most previous studies have examined emotion recognition in autism spectrum condition (ASC) without intellectual disability (ID). However, ASC and ID co-occur to a high degree. The main aims of the study were to examine emotion recognition in individuals with ASC and co-occurring intellectual disability (ASC-ID) as compared to individuals with ID alone, and to investigate the relationship between emotion recognition and social functioning. The sample consisted of 30 adult participants with ASC-ID and a comparison group of 29 participants with ID. Emotion recognition was assessed by the facial emotions test, while. social functioning was assessed by the social responsiveness scale-second edition (SRS-2). The accuracy of emotion recognition was significantly lower in individuals with ASC-ID compared to the control group with ID, especially when it came to identifying angry and fearful emotions. Participants with ASC-ID exhibited more pronounced difficulties in social functioning compared to those with ID, and there was a significant negative correlation between emotion recognition and social functioning. However, emotion recognition accounted for only 8% of the variability observed in social functioning. Our data indicate severe difficulties in the social-perceptual domain and in everyday social functioning in individuals with ASC-ID.

Foliar phenols and flavonoids level in pteridophytes: an insight to culturable fungal endophyte colonisation.

There are many available reports of secondary metabolites as bioactive molecules from culturable endophytes, nevertheless, there are scarce research pertaining to the levels of metabolites in plants with respect to the incidence and colonisation of fungal endophytes in the same foliar tissues. Therefore, the study was focussed to examine whether fungal endophyte colonisation and the accumulation of secondary metabolites, such as flavonoids and phenols, in the plants are related in any way. For this reason, the study aims to analyse phenols and flavonoids from the fronds of eleven pteridophytes along with the culture-dependent isolation of fungal endophytes from the host plants subsequently assigning them to morphological category and their quantitative analysis and further resolving its identities through molecular affiliation. The results revealed that nine morpho-categories of fungal endophytes were allotted based on culture attributes, hyphal patterns and reproductive structural characters. Highest numbers of species were isolated from Adiantum capillus-veneris and least was recorded from Pteris vittata and Dicranopteris linearis. Maximum phenol content was analysed from the fronds of P. vittata and lowest was recorded in A. capillus-veneris. Highest flavonoid content was measured in D. linearis and lowest was detected in Christella dentata. Significant negative correlation was observed between phenol content of ferns and species richness of fungi. Moreover, significant positive correlation was observed with the relative abundance of Chaetomium globosum and flavonoid content of ferns and negative significant relation was found between relative abundance of Pseudopestalotiopsis chinensis and phenol content of pteridophytes. The occurrence and the quantitative aspects of endophytes in ferns and their secondary metabolites are discussed.

Immune profile of patients‑a new approach in management of sepsis and septic shock?

The present study was a prospective observational single center study, enrolling 102 patients with sepsis, admitted in the Intensive Care Unit of the County Emergency Clinical Hospital in Târgu Mureș (Mureș, Romania). The main goal of the present study was to compare the changes of the following parameters on day 1 compared with day 5, in sepsis compared with septic shock, as well as in survivors compared with non-survivors: Cell blood count parameters, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and systemic inflammation index, C reactive protein (CRP), ferritin, procalcitonin (PCT), CD 3+ T cells, CD4+ T cells, CD8+ T cells, CD16+CD56+/CD3-NK cells and CD19+ B cells. The relationship between the subcategories of lymphocytes with the inflammatory markers was evaluated. The serum concentration of CRP and PCT was significantly lower on day 5 compared with day 1 and serum ferritin was significantly higher in patients with septic shock. The percentage of cytotoxic T lymphocytes was significantly decreased and the percentage of NK lymphocytes was significantly increased in patients who developed septic shock. The results indicated a negative significant correlation between the proportion of T lymphocytes and PCT concentration and a positive significant correlation between the proportion of B lymphocytes and PCT concentration.

Peripheral T cell immune repertoire is associated with the outcomes of acute spontaneous intracerebral hemorrhage.

Systematic immune responses have been identified in patients with acute spontaneous intracerebral hemorrhage (ICH). T cells have been established to participate in central nervous system damage and repair following brain injury. However, their contribution to the prognosis of patients with ICH remains to be elucidated. In this study, peripheral blood mononuclear cells (PBMCs) were collected from 45 patients with acute spontaneous ICH (<24 h from symptom onset). Our results exposed significant negative correlations between hematoma volume/white blood cell (WBC) density and Glasgow Coma Scale (GCS) score. Contrastingly, lymphocyte density was negatively correlated with hematoma volume and positively correlated with GCS score. Moreover, flow cytometry determined that ICH activated T cells despite their proportion being lower in blood. Afterward, immune repertoire sequencing (IR-seq) revealed a significant decrease in VJ, VDJ usage, and TCR clonotypes in ICH patients. Finally, variations in the complementarity-determining region 3 (CDR3) amino acid (aa) were also detected in ICH patients. This study reveals the occurrence of peripheral T-cell diminishment and activation in response to acute hematoma. ICH lesion also alters the T cell receptor (TCR) immune repertoire, which is associated with patient prognosis.