Significant Differences In Depression Scores Research Articles

Rapid and sustained antidepressant effects of intravenous ketamine in treatment-resistant major depressive disorder and suicidal ideation: a randomized clinical trial

BackgroundMajor depressive disorder (MDD) is the most disabling and burdensome mental disorder, negatively affecting an individual’s quality of life and daily functioning. the current study was conducted with the aim of investigating the clinical effects of intravenous ketamine on symptoms of MDD and suicidal ideation.MethodsThe current randomized clinical trial was carried out on 64 patients diagnosed with treatment-resistant major depressive disorder between April and August 2022. The participants were randomly assigned to two groups: the intervention group received a dose of 0.5 mg/kg of ketamine, while the control group received normal saline. The Montgomery-Asberg Depression Scale and Beck’s Suicidal Ideation Scale were utilized to assess depression and suicidal ideation, respectively.ResultsOne hour after the administration of ketamine treatment, there was a notable and significant improvement in both depression symptoms (35.16 ± 8.13 vs. 14.90 ± 10.09) and suicidal ideation (6.74 ± 6.67 vs. 0.42 ± 1.52). Moreover, there were statistically significant differences in depression scores between the two groups at one hour, four hours, one day, three days, one week, one month, and two months after the administration of ketamine (p-value < 0.001). However, ketamine recipients frequently experienced side effects such as increased heart rate, headache, dizziness, and dissociative syndrome symptoms.ConclusionThe observed rapid onset of action and sustained effect demonstrate the potential of ketamine to provide relief from depressive symptoms in a shorter timeframe compared to traditional treatment approaches. These findings contribute to the growing body of evidence supporting the use of ketamine as a valuable therapeutic option for patients with treatment-resistant depression.IRCT registrationIRCT registration number: IRCT20210806052096N1; IRCT URL: https://www.irct.ir/trial/62243; Ethical code: IR.ZUMS.REC.1400.150; Registration date: 2022-04-09.

Effect of Dancing Interventions on Depression and Anxiety Symptoms in Older Adults: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis (PROSPERO CRD42023428105) investigated the effect of dancing on depression and anxiety symptoms in older adults. Conducted up to October 2023, the search across seven databases and gray literature yielded 5020 records. Only randomized trials that analyzed dance interventions for depression and/or anxiety in older adults were included. Nineteen randomized trials, involving 508 participants in dance classes lasting 5 weeks to 18 months, were included and 16 were subjected to meta-analysis. Risk of bias was assessed using the Cochrane tool. The meta-analysis showed a statistically significant reduction in depression among older adults participating in dance interventions (p < 0.01). A decrease in depressive symptoms was significant compared to that in those involved in no other intervention (p = 0.02) but not compared to that achieved with other interventions in control groups (p = 0.96). Subgroup analysis showed no significant differences in depression scores for those with mild cognitive impairment (p = 0.47). These conclusions are associated with moderate bias and very low certainty. Due to heterogeneity and the small number of studies, conclusions for anxiety outcomes could not be drawn. These results underscore the potential clinical relevance of integrating dance into mental health interventions for older adults, thereby highlighting a promising avenue for enhancing the mental well-being of this demographic.

58 Sex Differences in the Relationship Between Sleep Disruption and Depressive Symptoms During Acute and Chronic Stages of Mild Traumatic Brain Injury (mTBI)

Objective:mTBI is trauma to the brain due to a blow or other mechanical force affecting the head. Prior research has established that common symptoms of mTBI include decreased sleep quality and onset/worsening of emotional dysregulation. However, there is little published research investigating how sleep disruption and depressive symptoms are experienced at varying stages of mTBI. We hypothesized that sleep disruption would change with differing time since injury, and that depressive symptoms should accordingly. Additionally, since females tend to have higher rates of depression, we predicted that there would be a significant difference between the sexes at different stages post-mTBI.Participants and Methods:This study included 145 healthy adults, split into six groups, comparing healthy controls consisting of 15 males (Mage=23.67, SD=5.066) and 17 females (Mage=25.35, SD=7.035) to individuals who had mTBI, 41 males (Mage=26.88, SD=8.509) and 72 females (Mage=23.79, SD=6.898) at five points post-mTBI: 2 weeks and 1, 3, 6, and 12 months. The Pittsburgh Sleep Quality Index (PSQI) global score was used to assess individual sleep quality and disturbances; higher scores indicated poorer sleep quality. The Beck Depression Index (BDI-II) was used to assess characteristics and symptoms of depression. We adjusted the score to exclude item 16, which measures changes in sleep. Higher scores indicate more severe depressive symptoms. We conducted a multivariate analysis of variance and Pearson correlation to examine whether there were significant differences in sleep and depression at different stages of mTBI for each sex.Results:We discovered that sleep quality was worse at chronic stages of mTBI (i.e, 12M, p=&lt;.001), than at acute stages (2W, p=.049), and compared to healthy controls. There were also significant differences in depression scores compared to healthy controls at 2W, p=.008, 3M, p=&lt;.001, and 6M, p=.012, but not 12M, p=.313, suggesting that depressive symptoms resolved by 12M in those with mTBI. To explain this, we investigated sex differences, as males tend to experience fewer depressive disorders than females. However, females reported fewer depressive symptoms than males at chronic stages of mTBI. This finding was not statistically significant as females had a Mbdi_total=6.84, SD=7.98 and males had a Mbdi_total=5.38, SD=6.078; still, this could be due to the low statistical power of the study, and with a larger sample size, could produce statistically significant differences between the sexes. Despite this, there is a statistically significant difference in the depression score for females between 2W and 12M post-mTBI (p=.046; effect size of d=.99). Comparatively, males showed no significant divergence between depression and sleep scores.Conclusions:Sleep disruption and depressive symptoms were correlated in individuals with mTBI in both acute and chronic stages; however, at 12M, there was a decrease in this correlation due to females exhibiting fewer depressive symptoms in combination with greater sleep disruption in the chronic phase of mTBI. Further research investigating the relationship between depression and sleep quality by looking at females with a much larger sample size would be helpful in clarifying these associations.

The influence of glioblastoma on patients' cognitive and demographic characteristics and psychological well-being of patients and caregivers: a single-centre retrospective study.

Glioblastoma, the most aggressive primary brain tumour in adults, poses significant challenges for patients and their caregivers. This study investigates a range of clinical parameters, such as symptoms, tumour characteristics, presence of seizures, mental status, and depression/anxiety, in glioblastoma patients. The rapid deterioration of physical and cognitive functions experienced by patients can have profound effects on both patients and their relatives throughout the course of the disease. The objective of this study was to examine and compare psychological symptoms between glioblastoma patients and their relatives. The study included 98 adult patients with glioblastoma who underwent pre- and postoperative cognitive assessments using the Mini-Mental State Examination (MMSE). The Hospital Anxiety and Depression Scale (HADS) was also used to evaluate and compare psychological symptoms of patients and their relatives over time. Seizures were seen in 45.9% of patients, and the mean age of the patients was 60.1 ± 13.8 years. The patients were evaluated at various time intervals before and after surgery, and the data were retrospectively analyzed. The study found that before surgery, the anxiety levels of caregivers were significantly higher than those of patients during all evaluation periods. Additionally, the depression scores of caregivers were significantly higher than those of patients only in the first month following the operation. There were no significant differences in depression scores between patients and caregivers in the other assessment intervals. The average cognitive level of patients, as assessed by the MMSE scale was 22.4 before the operation and 20.9 after the operation. Glioblastoma has a significant impact on the mental health and emotional well-being of both patients and their relatives. This study highlights the importance of providing early support to both patients and their relatives before surgery. The study's strength is that it focuses on an early time point, prior to surgery, where both patients and their relatives are already affected and may require additional support. The results of this study can help healthcare professionals to better understand the psychological impact of glioblastoma and provide more targeted support to patients and their caregivers.

The effect of symptomatology and mental wellbeing on quality of life in people with acoustic neuroma

IntroductionAcoustic neuroma (AN) research largely employs a medical framework to understand health outcomes. An alternative is to examine quality of life (QOL) outcomes. This study explored whether mental well-being (i.e., anxiety and depression) were predictive of QOL in those with AN over and above symptomatology. MethodsA nationwide online survey was distributed to 24 community organisations. The inclusion criteria were a diagnosis of AN irrespective of the treatment approach. There were 52 respondents. Mental well-being was assessed using the Hospital Anxiety and Depression Scale (HADS), and quality of life was assessed using Penn Acoustic Neuroma QOL scale (PANQOL). ResultsThe most frequently reported symptoms reported were poor balance, tinnitus, hearing loss, and headache. Preliminary analyses suggested that headaches, tinnitus and mental well-being were significantly correlated with QOL. Hierarchical regression revealed that these two symptoms and mental well-being accounted for 18.7% and 51.1% of the variance in QOL, respectively. In addition, there was a significant difference in depression scores between management types, with the surgery group having a significantly higher depression score than the radiation group. ConclusionSymptoms and mood contribute to QOL for those diagnosed with AN. This can be understood through the common-sense model and fear of cancer recurrence. Screening for psychological difficulties should be provided from the point of diagnosis to post-treatment to allow for targeted management plans to mitigate the effects of these on QOL.

Theta-burst stimulation of TMS treatment for anxiety and depression: A FNIRS study

BackgroundThis study aimed to evaluate the intervention effect of intermittent Theta burst stimulation (iTBS) on anxiety and depression by using Functional Near-Infrared Spectroscopy technology for confirming the effect of iTBS on anxiety and depression and providing new parameter basis for the treatment and development of rTMS. Method37 patients with anxiety and depression were treated with rTMS intervention in iTBS mode, and the symptoms of depression and anxiety were assessed by Hospital Anxiety and Depression Scale at baseline and after 10 times of treatments. The brain activation was assessed by verbal fluency task. The scores of anxiety and depression were analyzed by paired sample t-test. ResultsAfter 10 times of rTMS treatment in iTBS mode, the symptoms of anxiety and depression in patients were relieved. The anxiety scores before and after treatment were significantly different, and the post-test scores were significantly lower than the pre-test scores. Significant differences in depression scores were observed before and after treatment, and the post-test score was significantly lower than the pre-test score. In the brain functional connection, the connection of various brain regions was strengthened, and the strength of functional connection between all ROIs before the intervention was significantly lower than that after the intervention. Statistical significance was observed. ConclusionThe intervention of iTBS model has a positive effect on improving symptoms and strengthening brain functional connection of patients with anxiety and depression. This performance supports the effectiveness of iTBS model in treating anxiety and depression.

Comparing the effectiveness of metacognitive therapy and the integration of metacognitive therapy with an evolutionary psychotherapy approach in reducing depression symptoms

Background and Objective: Depression has been identified as the third leading cause of non-fatal global health loss in 2017, affecting more than 300 million people worldwide. The present study was conducted with the aim of comparing the effectiveness of metacognitive therapy and combining metacognitive therapy with an evolutionary psychotherapy approach in reducing depression symptoms. Methods: The data collection method is semi-experimental with pre-test-post-test and control group with two-month follow-up. The statistical population of the research includes women with depression. In the first stage, 45 women with depression were selected as the statistical sample of the study based on the available sampling method, and in the next stage, they were divided into three groups through a simple random sampling method. Metacognitive therapy (15 people), combining metacognitive therapy with evolutionary psychotherapy (15 people) and the control group (15 people) were included, and Beck's depression questionnaires (1961) were completed in three stages: pre-test, post-test and follow-up. Results: The results of the research showed that there was a significant difference between the depression scores in the two groups of metacognitive therapy and the combination of metacognition and developmental therapy, which was in favor of the group of metacognition and developmental therapy (p&lt;0.05). The results also showed that there was a significant difference in depression scores between metacognitive therapy and the control group, which was in favor of the metacognitive therapy group (p&lt;0.01). There was a significant difference in depression between the metacognitive integration and evolutionary therapy group and the control group (p&lt;0.01). Finally, the results showed that metacognition therapy was effective in depression scores (p&lt;0.01) and the combination of metacognition with evolutionary therapy was effective in depression scores (p&lt;0.01). Conclusion: It can be concluded that metacognition therapy and the combination of metacognition with evolutionary therapy were effective in reducing the symptoms of depression. Also, the combination of metacognition and evolutionary therapy was more effective in reducing depression symptoms than metacognitive therapy.

Efektivitas Terapi Reminiscence untuk Mengurangi Depresi pada Lansia dengan Penyakit Kronis

&lt;p&gt;Old age is the last period of life, where at this time, the elderly experience setbacks in various aspects of life, especially in physical, psychological, and social functions. Elderly people with chronic diseases tend to be helpless in dealing with their chronic diseases, so that elderly people with chronic diseases are prone to depression. The purpose of this study was to examine the effect of Reminiscence Therapy in reducing depression in the elderly with chronic diseases. This study involved 5 elderly participants with chronic diseases who had major depression. The research method used is one group pretest-posttest design. Based on the results of the Wilcoxon Signed Rank Test, there was a significant difference in depression scores between before and after being given Reminiscence Therapy (0.023; p&amp;lt;0.05). So, it can be concluded that Reminiscence Therapy can reduce depression in the elderly with chronic diseases.&lt;/p&gt;

THE IMPACT OF RELATIVE INCOME ON FARMERS' PSYCHOLOGICAL CAPITAL AND ANXIETY INHIBITION: EVIDENCE FROM CHINA

THE IMPACT OF RELATIVE INCOME ON FARMERS' PSYCHOLOGICAL CAPITAL AND ANXIETY INHIBITION: EVIDENCE FROM CHINA

Comparison between preoperative and postoperative depression scores among genitourinary fistula patients.

Objective: To compare depression scores in genitourinary fistula patients according to Glasgow depression scale pre and postoperatively in tertiary care hospital. Study Design: Prospective Cohort study. Setting: Inpatient and Outpatient Department of Gynecology and Obstetrics, Isra University Hospital Hyderabad. Period: December 2018 to December 2019. Material &amp; Methods: Patients with confirmed genitourinary fistulas undergoing corrective surgery were included. Glasgow Depression scale questionnaire was filled in Gynae ward at time of admission, postoperatively at discharge (14-21 days after surgery) and at 6 months follow-up after discharge in Urogynaecological Out Patient Department. In Glasgow depression scale 20 questions were asked from patients scoring 0,1 and 2 according to answers. Those scored greater than 13 were referred to primary mental health care center and Psychologist. Results: Total of 164 patients had successful genitourinary fistula repair. The average age of women was 47.63 (SD = ±17.1) years. Mean of depression scores preoperatively, at time of discharge and after 6 months of discharge was 19.69 (SD= ±2.61), 14.90 (SD= ±2.22) and 11.34 (SD= ±2.01) respectively. Mean decrease in depression score from preoperative to six months after discharge was 8.35 units, considered statistically significant with p-value less than 0.01. Conclusion: There is significant difference in depression scores preoperatively and postoperatively. Psychological symptoms decreases after surgical correction of fistulas.

Mental Health and Related Factors of Adolescent Students During Coronavirus Disease 2019 (COVID-19) Pandemic.

Objective Adolescents are at a special stage of physical and mental development, which is a susceptible period for mental disorders. Since the outbreak of coronavirus pneumonia in December 2019, long term stress may have negative effects on the mental health of the adolescents. In the context of the coronavirus disease 2019 (COVID-19), the study was designed to investigate the mental and psychological health of adolescents in China and its possible related factors. Methods A cross-sectional study design was adopted using a structured questionnaire which were distributed through the Internet to measure depression, anxiety, life events and stress related factors. Descriptive statistics and multiple regression analyses were conducted to process the data. Results The final sample comprised 795 adolescents. The total detection rate of depression was 76.48% and the total detection rate of anxiety was 33.08%. ANOVA showed that there were significant differences in depression scores in terms of gender, anxiety scores, history of mental disorders, COVID-19 knowledge reserve, family and social contradictions (p<0.05). And there were significant differences in anxiety scores in terms of gender, depression scores, mental health knowledge reserves, family and social contradictions (p<0.05). Multiple regression analysis showed that anxiety score, health status and COVID-19 knowledge reserve were positively associated with depression score (p<0.01), and history of psychosocial disorders was negatively associated with depression score (p<0.05); depression score, family and social contradictions were significantly positively correlated with anxiety score (p<0.01), and history of mental disorders was significantly negatively correlated with SDS score (p<0.01). Conclusion During the outbreak of COVID-19, adolescent students with better understanding of the pandemic, more complete knowledge of mental health, and better family and social relationship had less impact on their mental health. Therefore, to ensure a sound social support system, elaborate health instruction, and family communication and mutual understanding are conducive to alleviating the psychological stress caused by the epidemic, and it is positive for adolescent students to maintain a good mental health.

A comparative study to assess mental health literacy, impact of event, depression, anxiety, and stress levels of medical and other students during the second wave of the COVID-19 pandemic

Background: COVID-19 pandemic is negatively affecting the mental health of medical professionals as well as medical students, as they stand in the frontline. Medical education is recognized as stressful across the globe and in the hour of present crisis, students have to stay back home and continue their studies online. Aims: The aim of the study is to compare the emerging evidence of the effects of the COVID-19 outbreak on mental health and assess mental health awareness of medical students and other students studying in a Medical College of Eastern India. Materials and Methods: This cross-sectional observational study was conducted in a period of 3 months after taking Institutional ethical clearance and informed consent of the subjects. 212 medical students and 101 students of other courses studying in the college participated in the study. The present survey was conducted online using Google Forms. In the first section of the form, purpose of the study was explained and informed consent was taken from the participants. In the second part of the form, participants were asked to fill up demographic details and relevant history; in the third part, participants had to fill up three scales: Depression, Anxiety and Stress Scale-21, Impact of Event Scale-Revised (IRE-R), Mental Health Literacy Scale. Results: There was no significant difference in depression scores between the two groups. Anxiety scores and stress scores were significantly higher among medical students as compared to the other group with P = 0.0017 and 0.008, respectively. Group A: Anxiety scores 12.34 ± 8.5; Stress scores - 13.07 ± 8.01. Group B: Anxiety scores 9.34 ± 7.34; Stress scores - 10.55 ± 7.62. There was no significant difference in mental health literacy scores between the two groups. Mental Health literacy scores of Group A: 96.84 ± 17.29; Mental health literacy score of Group B: 99.86 ± 13.39; P = 0.09. No difference in IRE-R scores between the two groups was observed. Group A: Total score - 21.81 ± 14.34; Avoidance scale - 9.43 ± 6.1; intrusion scale 8.58 ± 5.12; Hyperarousal scale - 3.79 ± 2.94. Group B: Total score - 20.39 ± 14.34; Avoidance scale - 9.06 ± 6.5; Intrusion scale - 7.84 ± 5.95; Hyperarousal scale - 3.49 ± 3.21. Conclusions: Mental health literacy scores and impact of event score were similar in medical and other students studying in the same medical institution. Medical students had significantly higher levels of anxiety and stress as compared to the other group, though depression scores of both groups were comparable. Hence, it may be concluded that medical students perceived higher levels of anxiety and stress during the second wave of the present COVID-19 pandemic.

A study of depression, partnership and sexual satisfaction in patients with post-traumatic olfactory disorders

Post-traumatic olfactory dysfunction (PTOD) is associated with a significant decrease in quality of life. The present study aimed to explore whether PTOD is associated with depression and changes in sexuality. There were two groups in this case–control study. The patient group consisted of patients with PTOD (n = 55), and the control group comprised healthy individuals without the olfactory disorder (n = 115). Olfactory function, depression, partnership, and sexual satisfaction were assessed using the Iranian version of the Sniffin’ Sticks test (Ir-SST), Beck Depression Inventory (BDI), Enrich Couple Scale (ECS) and Sexual Satisfaction Scale for Women (SSSW). The BDI scores were higher in the patient group than in the control group (p < 0.001). The SSSW score was lower in the patient group than in controls (p < 0.01), although the ECS score was not significantly different between patients and controls. Also, there was no significant difference in the severity of trauma between marital satisfaction and sexual satisfaction. However, the analysis showed a statistically significant difference in depression scores in connection with the head trauma severity. In the PTOD group, depression was increased and sexual satisfaction declined. Understanding the association of olfactory dysfunction with depression and sexuality allows patients and doctors to deal with less notable consequences of this disorder.

The effects of auricular acupressure on stress, anxiety, and depression of outpatient nurses in South Korea

Background and purposeOutpatient nursing is an occupation with high emotional labor and job stress. The purpose of this study was to examine the effects of auricular acupressure on stress, anxiety, and depression of outpatient nurses. Materials and methodsThe study design was a randomized controlled trial. Participants were 54 outpatient nurses, divided into an experimental (n = 28) and a control group (n = 26). Auricular acupressure using vaccaria seeds was administered to the experimental group, while placebo auricular acupressure using vaccaria seeds was administered to the placebo group. Sessions continued for 5 weeks. Outcome measurements included blood tests such as cortisol and serotonin. ResultsThere was a statistically significant difference in depression scores (t = 3.111, p = 0.002) and serotonin levels (t = 6.304, p < 0.001) between the experimental and placebo groups. Auricular acupressure decreased depression scores, and the depression-related physiological index, serotonin, also changed significantly. ConclusionAuricular acupressure using vaccaria seeds was effective in decreasing depression in outpatient nurses.

The relationship between socioeconomic status and depression among the older adults: The mediating role of health promoting lifestyle

BackgroundDepression is the most frequent psychiatric disorder among the older adults, the purpose of this study is to explore the mediation effect of health promoting lifestyle on the relationship between Socioeconomic Status (SES) and depression, so as to provide practical reference for effectively preventing and alleviating depression of the older adults. MethodsA multi-stage random sampling method was conducted in Shanxi Province. A total 8526 older adults were included in the analysis. Regression analysis was used to explore the relationship between the socioeconomic status, health promoting lifestyle and depression, and the mediation effect test process was used to verify the mediating mechanism of health promoting lifestyle on this relationship. Results62.1% of the older adults had depression symptoms in this study, and there were significant differences in depression scores among the older adults with gender, age, residence, marital status, endowment pattern, self-care ability, exercise frequency, physical examination frequency, daily diet rules(P<0.05). The results of mediating effect analysis showed that health promoting lifestyle as mediation effect between social economic status and depression was established, and the mediating effect was accounted for (a*b/c) 63.1%. LimitationsGiven the cross-sectional study, it is not possible to make causal inferences. ConclusionsThere were different degrees of depression in the older adults. The lower the SES is, the higher the risk of depression is. This result once again confirms the social causation theory. Combined with the theory of health risk behavior, the study further confirmed the applicability of lifestyle mechanism in the intermediate mechanism of the relationship between SES and depression in the elderly. Thus, in addition to providing material support and financial assistance, helping the elderly develop a healthy lifestyle is also effective measure to improve their depression.

Psychosocial outcomes of group prenatal care

Group prenatal care provides an alternative model of prenatal care that allows for collaboration with peers, education, discussion, and self-management training in addition to standard prenatal care. Previous research on group prenatal care has demonstrated a decreased risk of preterm labor and of low birth weight babies, increased pregnancy knowledge, and decreased perceived stress in certain populations. CenteringPregnancy®, an evidence-based model of group prenatal care, has been the focus of group prenatal care research, which has demonstrated such improvements in health outcomes as well as positive health behaviors. Could CenteringPregnancy® also reduce rates or severity of depression through its potential to increase support and knowledge of pregnancy for patients? This study aims to assess factors that may reduce risk of depression as well as rates of depression in women enrolled in CenteringPregnancy® compared to women in traditional, individual care. This non-randomized study collected data from patients at their initial obstetric visit and again at their postpartum visit to compare psychosocial outcomes between those participants in CenteringPregnancy® versus individual prenatal care. The majority (64%) of primiparous women chose CenteringPregnancy® (×2 = 8.6399, df = 2, p = 0.003). A significant increase in Pregnancy Knowledge Scale (PKS) scores was observed in the CenteringPregnancy® group (p = 0.0278). Women in both groups revealed no significant difference in depression scores, as measured by the Edinburgh Postnatal Depression Scale (EPDS). Our research adds support to current literature suggesting group prenatal care is equivalent to, and perhaps more beneficial (in certain psychosocial arenas) than traditional prenatal care (Lathrop in Nurs Womens Health 17:118–130, 2013).

Comparison of pre- and post-hemodialysis PHQ-9 depression scores in patients with end-stage renal disease: A cross-sectional study.

An overlap between the somatic symptoms of depression and those of uremia seen in end-stage renal disease (ESRD) patients may affect the diagnosis of depression. This study aims to evaluate the effect of hemodialysis on the diagnosis of depression among patients on maintenance hemodialysis as dialysis diminishes the uremic symptoms, and to compare depression scores before and after dialysis. This was a cross-sectional analytic study conducted from November 2018 through April 2019, in three tertiary hospitals. Consenting participants aged 18 years or older, who had received hemodialysis for at least three months were included. The Patient Health Questionnaire (PHQ-9) tool was used to collect patients' data and to identify symptoms of depression Pre- and post-hemodialysis. Depression scores were compared using the paired sample Wilcoxon rank test or the McNemar test, where appropriate. Overall, 163 participants were enrolled in the study. The average age of the participants was 56.5 years old, whereas 44.8% were females. The prevalence of depressive symptoms before hemodialysis was 48.5%, with prevalence of mild, moderate and moderately severe of 34.4%, 11.7% and 2.5%, respectively. On the other hand, the prevalence of depressive symptoms after hemodialysis was 46.6% with 36.8%, 9.2% and 0.6% of the participants reporting mild, moderate and moderately severe symptoms, respectively. We found no significant difference in depression scores before and after dialysis (p-values > 0.05). Our study supports the fact that the prevalence of depression is high among patients with ESRD on maintenance hemodialysis. We didn't find a significant difference in depression scores among hemodialysis patients before and after dialysis, with negligible effect of uremic symptoms on the diagnosis of depression. We suggest adopting routine screening of depression among this high-risk group of patients.

Online yoga to reduce post traumatic stress in women who have experienced stillbirth: a randomized control feasibility trial

BackgroundAbout 1 in every 150 pregnancies end in stillbirth. Consequences include symptoms of post traumatic stress disorder (PTSD), depression, and anxiety. Yoga has been used to treat PTSD in other populations and may improve health outcomes for stillbirth mothers. The purpose of this study was to determine: (a) feasibility of a 12-week home-based, online yoga intervention with varying doses; (b) acceptability of a “stretch and tone” control group; and (c) preliminary efficacy of the intervention on reducing symptoms of PTSD, anxiety, depression, perinatal grief, self-compassion, emotional regulation, mindfulness, sleep quality, and subjective health.MethodsParticipants (N = 90) were recruited nationally and randomized into one of three groups for yoga or exercise (low dose (LD), 60 min per week; moderate dose (MD), 150 min per week; and stretch-and-tone control group (STC)). Baseline and post-intervention surveys measured main outcomes (listed above). Frequency analyses were used to determine feasibility. Repeated measures ANCOVA were used to determine preliminary efficacy. Multiple regression analyses were used to determine a dose-response relationship between minutes of yoga and each outcome variable.ResultsOver half of participants completed the intervention (n = 48/90). Benchmarks (≥70% reported > 75% satisfaction) were met in each group for satisfaction and enjoyment. Participants meeting benchmarks (completing > 90% of prescribed minutes 9/12 weeks) for LD and MD groups were 44% (n = 8/18) and 6% (n = 1/16), respectively. LD and MD groups averaged 44.0 and 77.3 min per week of yoga, respectively. The MD group reported that 150 prescribed minutes per week of yoga was too much. There were significant decreases in PTSD and depression, and improvements in self-rated health at post-intervention for both intervention groups. There was a significant difference in depression scores (p = .036) and grief intensity (p = .009) between the MD and STC groups. PTSD showed non-significant decreases of 43% and 56% at post-intervention in LD and MD groups, respectively (22% decrease in control).ConclusionsThis was the first study to determine the feasibility and preliminary efficacy of an online yoga intervention for women after stillbirth. Future research warrants a randomized controlled trial.Trial registrationClinicalTrials.gov. NCT02925481. Registered 10–04-16.

The question of preoperative anxiety and depression in older patients and family protectors.

BackgroundHigher levels of anxiety increase the risks of surgery, including morbidity and mortality. The objectives of this study were to measure anxiety and depression during the preoperative period and to identify the degree of knowledge and concerns of older patients and their family protectors regarding anesthesia, and the causes of these concerns.MethodsWe administered a questionnaire to older patients scheduled to undergo surgery and their family protectors one day prior to the surgery. The questionnaire included tools for quantifying anxiety and depression (Anxiety-Visual Analogue Scale, the Amsterdam Preoperative Anxiety and Information Scale, State-Trait Anxiety Inventory Korean YZ Form, and Short Form Geriatric Depression Scale). We also asked about the concrete causes of anxiety using pre-created forms.ResultsThere were 140 older patients and family protectors who participated in the study. The majority of older patients (n = 114, 81.4%) undergoing surgery and their family protectors (n = 114, 81.4%) indicated that they were anxious. Most of the older patients and their family protectors responded that they had insufficient knowledge about anesthesia, and they were mostly worried about failure to awaken following surgery, and postoperative pain. Older patients with higher anxiety scores showed higher depression scores. There were significant differences in depression scores depending on the presence of cohabitating family members.ConclusionsIt is important to remember that older patients with higher depression scores have higher anxiety during the preoperative period.

Cross-Border Reproductive Care: Psychological Distress in A Sample of Women Undergoing In Vitro Fertilization Treatment with and without Oocyte Donation.

BackgroundCross-border reproductive care (CBRC) refers to the movement of patients to foreign countries for fertility treatment. Limited evidence indicates that this phenomenon is associated with a risk of psychologi- cal distress, but few studies on the psychological impact of CBRC are currently available. The aim of this study was to compare the anxiety and depression levels of a group of cross-border patients with a local Spanish patient group, both of which underwent in vitro fertilization (IVF) treatment. We also sought to explore the clinical, sociodemographic and personality profiles of the CBRC group and local women.Materials and MethodsThis present cross-sectional study was conducted on 161 infertile females (71 CBRC patients and 90 local women) who were undergoing IVF treatment. The following questionnaires were used to collect data: Spielberger State Anxiety Inventory (STAI-S), the Beck Depression Inventory-II (BDI-II) and the Zuckerman-Kuhlman Personality Questionnaire (ZKPQ). Sociodemographic, clinical, reproductive and CBRC variables were also recorded.ResultsCBRC patients, specifically CBRC oocyte recipients, showed higher levels of anxiety compared to lo- cal women. However, no significant differences in depression scores were found between both groups. Finally, when analysing personality, the Activity scale scores of the ZKPQ were found to be higher in CBRC oocyte recipients, which indicated a greater tendency for general activity and higher energy levels.ConclusionCBRC oocyte recipient women may have greater vulnerability to anxiety than local women prior to infertility treatment. Screening and psychological support protocols for anxiety in this population should be considered.