Significant Differences In Scores Research Articles

Shift schedule effects on firefighter health and fitness.

Firefighter health is of utmost importance both to first responders and the individuals they serve daily. The impact of shift schedule on firefighter health remains poorly understood. The purpose of this study was to examine differences in health and performance outcomes in firefighters across two different shift schedules. Firefighter (N = 1995) body composition, muscular strength, endurance, flexibility, and cardiorespiratory endurance were assessed and described. A Mann-Whitney U test was conducted to compare differences between shift schedules (48/96 and 4's and 6's). There was a statistically significant difference in BMI (U = 70115, z=-1.988, p = .047), BF% (U = 67341, z=-2.779, p = .005), and trunk flexion score (U = 81362, z = 1.979, p = .048) favoring the 48/96 shift schedule. Firefighters following a 48/96 shift schedule exhibited improved body composition and fitness performance in comparison to peers who followed a 4's and 6's shift schedule. Findings may guide regional firefighter scheduling to optimize health and performance.

Revealing the novel metabolism-related genes in the ossification of the ligamentum flavum based on whole transcriptomic data.

The ossification of the ligamentum flavum (OLF) is one of the major causes of thoracic myelopathy. Previous studies indicated there might be a potential link between metabolic disorder and pathogenesis of OLF. The aim of this study was to determine the potential role of metabolic disorder in the pathogenesis of OLF using the strict bioinformatic workflow for metabolism-related genes and experimental validation. A series of bioinformatic approaches based on metabolism-related genes were conducted to compare the metabolism score between OLF tissues and normal ligamentum flavum (LF) tissues using the single sample gene set enrichment analysis. The OLF-related and metabolism-related differentially expressed genes (OMDEGs) were screened out, and the biological functions of OMDEGs were explored, including the Gene Ontology enrichment analysis, Kyoto Encyclopedia of Genes and Genomes enrichment analysis, and protein-protein interaction. The competing endogenous RNA (ceRNA) network based on pairs of miRNA-hub OMDEGs was constructed. The correlation analysis was conducted to explore the potential relationship between metabolic disorder and immunity abnormality in OLF. In the end, the cell experiments were performed to validate the roles of GBE1 and TNF-α in the osteogenic differentiation of LF cells. There was a significant difference of metabolism score between OLF tissues and normal LF tissues. Forty-nine OMDEGs were screened out and their biological functions were determined. The ceRNA network containing three hub OMDEGs and five differentially expressed miRNAs (DEmiRNAs) was built. The correlation analysis between hub OMDEGs and OLF-related infiltrating immune cells indicated that metabolic disorder might contribute to the OLF via altering the local immune status of LF tissues. The cell experiments determined the important roles of GBE1 expression and TNF-α in the osteogenic differentiation of LF cells. This research, for the first time, preliminarily illustrated the vital role of metabolic disorder in the pathogenesis of OLF using strict bioinformatic algorithms and experimental validation for metabolism-related genes, which could provide new insights for investigating disease mechanism and screening effective therapeutic targets of OLF in the future.

Obesity Does Not Negatively Affect Patient-perceived Outcomes After Cervical Disc Replacement for Disc Herniation.

Retrospective review. To assess the impact of Body Mass Index (BMI) on patient-reported outcome measures (PROMs) after cervical disc replacement (CDR). BMI may affect PROMs after spine surgery. Primary CDR recipients for herniated disc(s) with BMI <40 were retrospectively selected from a single-surgeon registry. Cohorts were divided into non-obese (BMI <30) and obese (BMI ≥30). Intercohort in-hospital complication rates were compared through independent samples t tests. Pre/postoperative PROMs were compared between cohorts through multivariable regression accounting for demographic differences. Final follow-up dates between patients averaged 11.8 ± 9.3 months. PROMs assessed included Patient-reported Outcomes Measurement Information System-Physical Function, Neck Disability Index, Visual Analog Scale-Neck, Visual Analog Scale-Arm, and the 9-item Patient Health Questionnaire. Improvements in PROMs were evaluated and compared at each follow-up within cohorts through paired t tests. The magnitude of improvement in PROMs from preoperative baseline at 6-week follow-up (∆PROM-6W) and final follow-up (∆PROM-FF) along with achievement rates of minimum clinically important differences were compared between cohorts through multivariable regression accounting for demographic differences. Of 153 patients, 53 patients were noted as obese. Demographic differences included age, prevalence of hypertension and diabetes, and comorbidity burden scores ( P ≤ 0.011, all). No significant variations in in-hospital complications were found. The non-obese cohort demonstrated improvements in all PROMs at 6 weeks and final follow-up periods ( P ≤ 0.005, all). The obese cohort demonstrated improvements in all postoperative PROMs besides 9-item Patient Health Questionnaire at 6 weeks ( P ≤ 0.015, all). After accounting for age and comorbidity variations, there were no significant intercohort differences in raw PROM scores, ∆PROM-6W, ∆PROM-FF, or minimum clinically important difference achievement rates. Regardless of BMI, patients experience significant improvements in physical function, disability, pain, and mental health after CDR for disc herniation. Patients with obesity do not suffer inferior patient-perceived outcomes after CDR. These findings may help surgeons counsel patients in the preoperative period.

Sex differences in the SOFA score of ICU patients with sepsis or septic shock: a nationwide analysis

BackgroundThe Sequential Organ Failure Assessment (SOFA) score is an important tool in diagnosing sepsis and quantifying organ dysfunction. However, despite emerging evidence of differences in sepsis pathophysiology between women and men, sex is currently not being considered in the SOFA score. We aimed to investigate potential sex-specific differences in organ dysfunction, as measured by the SOFA score, in patients with sepsis or septic shock and explore outcome associations.MethodsRetrospective analysis of sex-specific differences in the SOFA score of prospectively enrolled ICU patients with sepsis or septic shock admitted to one of 85 certified Swiss ICUs between 01/2021 and 12/2022.ResultsOf 125,782 patients, 5947 (5%) were admitted with a clinical diagnosis of sepsis (2244, 38%) or septic shock (3703, 62%). Of these, 5078 (37% women) were eligible for analysis. A statistically significant difference of the total SOFA score on admission was found between women (mean 7.5 ± SD 3.6 points) and men (7.8 ± 3.6 points, Wilcoxon rank-sum p < 0.001). This was driven by differences in the coagulation (p = 0.008), liver (p < 0.001) and renal (p < 0.001) SOFA components. Differences between sexes were more prominent in younger patients < 52 years of age (women 7.1 ± 4.0 points vs men 8.1 ± 4.2 points, p = 0.004). No sex-specific differences were found in ICU length of stay (women median 2.6 days (IQR 1.3–5.3) vs men 2.7 days (IQR 1.2–6.0), p = 0.13) and ICU mortality (women 14% vs men 15%, p = 0.17).ConclusionSex-specific differences exist in the SOFA score of patients admitted to a Swiss ICU with sepsis or septic shock, particularly in laboratory-based components. Although the clinical meaningfulness of these differences is unclear, a reevaluation of sex-specific thresholds for SOFA score components is warranted in an attempt to make more accurate and individualised classifications.Graphical abstract

Health-related outcomes 6 months after integrated care of older people with stroke in 2 different primary care settings.

Integrated care has been proven to be effective among stroke survivors. However, in China, these services mainly focus on connecting the healthcare system (acute, primary medical, and skilled) at the individual level. Closer health and social care integration is a new concept. This study aimed to compare health-related outcomes 6 months after the implementation of the 2 integrated care models. It was a 6-month follow-up of an open, prospectively study comparing the outcomes of a model of integrated health and social care (IHSC) versus a usual integrated healthcare (IHC) model. Outcomes were measured by Short-Form Health Survey-36 (SF-36), Modified Barthel Index (MBI), and Caregiver Strain Index (CSI) at 3 and 6 months, respectively. There were no statistically significant differences in MBI scores between patients in the 2 models either after 3 months or at the end of intervention. The same trend was not seen in Physical Components Summary, an integral component of SF-36. Patients in IHSC model scored statistically significant higher points in Mental Components Summary, another integral part of SF-36 than patients in IHC model after 6 months. Average scores of CSI were statistically significant lower for IHSC model than for IHC model after 6 months. The findings suggest the need to improve the scales of integration and recognize the vital role played by social care services when designing or improving an integrated care for older people with stroke.

Fluorescein-guided surgery in high-grade gliomas: focusing on the eloquent and deep-seated areas

PurposeThe vital function of eloquent and deep brain areas necessitates precise treatment for tumors located in these regions. Fluorescein-guided surgery (FGS) has been widely used for high-grade gliomas (HGGs) resection. Nevertheless, the safety and efficacy of utilizing this technique for resecting brain tumors located in eloquent and deep-seated areas remain uncertain. This study aims to assess the safety and extent of resection of HGGs in these challenging tumors with fluorescein and explore its impact on patient survival.MethodsA retrospective analysis was conducted on the clinical and radiological data of 67 consecutive patients with eloquent or deep-seated HGGs who underwent surgery between January 2020 and June 2023. Lacroix functional location grade was used to determine the eloquence of the tumors. The comparison between the fluorescence-guided surgery group (FGS, n = 32) and the conventional white-light microscopic surgery group (non-FGS, n = 35) included assessments of extent of resection (EOR), rates of gross total resection (GTR, 100%) and near-total resection (NTR, 99 to 98%), postoperative Neurologic Assessment in Neuro-Oncology (NANO) scores, overall survival (OS), and progression-free survival (PFS), to evaluate the safety and efficacy of fluorescein-guided technology in tumor resection at these specific locations.ResultsBaseline of demographics, lesion location, and pathology showed no significant difference between the two groups. GTR of the FGS group was higher than the non-FGS group (84.4% vs. 60.0%, OR 3.60, 95% CI 1.18–10.28, p < 0.05). The FGS group also showed higher GTR + NTR (EOR ≥ 98%) than the non-FGS group (93.8% vs. 65.7%, OR 7.83, 95% CI 1.86–36.85, p < 0.01). 87.0% of eloquent tumors (Lacroix grade III) in the FGS group achieved GTR + NTR, compared to 52.2% of control group (OR 6.11, 95% CI 1.50–22.78, p < 0.05). For deep-seated tumors, the rate of GTR + NTR in the two groups were 91.7% and 53.3%, respectively (OR 9.62, 95% CI 1.05–116.50, p < 0.05). No significant difference of the preoperative NANO score of the two groups was found. The postoperative NANO score of the FGS group was significantly lower than the non-FGS group (2.56 ± 1.29 vs. 3.43 ± 1.63, p < 0.05). Median OS of the FGS group was 4.2 months longer than the non-FGS group despite no statistical difference (18.2 months vs. 14.0 months, HR 0.63, 95% CI 0.36–1.11, p = 0.112), while PSF was found significantly longer in FGS patients than those of the non-FGS group (11.2 months vs. 7.7 months, HR 0.59, 95% CI 0.35–0.99, p < 0.05).ConclusionSodium fluorescein-guided surgery for high-grade gliomas in eloquent and deep-seated brain regions enables more extensive resection while preserving neurologic function and improve patient survival.

A cross-sectional study of Hispanic and Latina/o/x/e individuals’ acute coronary syndrome symptom knowledge, attitudes, and beliefs

BackgroundLittle attention has been placed on language proficiency as a potential variable affecting ACS symptom knowledge, attitudes, and beliefs. ObjectivesTo compare the ACS symptom knowledge, attitudes, and beliefs of Hispanic and Latina/o/x/e individuals proficient in English and in those only proficient in Spanish. Secondary aims were to determine if there were differences in ACS symptom knowledge, attitudes, or beliefs based on participants’ previous exposure to ACS symptom information and to evaluate instrument characteristics of the new Spanish version of the ACS Response Index. MethodsThis cross-sectional, comparative study included participants (N = 99) from a community-based clinic in Illinois. Knowledge, attitudes, and beliefs related to ACS symptoms were measured using the ACS Response Index. ResultsThe average participant was 39.8 (SD 15.6) years of age, female (n = 56, 56.6 %), and had a high school education or less (n = 61, 61.6 %). Participants correctly classified a mean 57.5 % (SD 12.8) of symptoms and had mean attitude and belief scores of 12.1 (SD 3.3) and 17.5 (SD 2.9), respectively. There were no significant differences in knowledge, attitudes, and beliefs based on language proficiency. However, there were some statistically significant differences for knowledge and attitude scores based on exposure to ACS symptom information. The ACS Response Index (Spanish Version) also demonstrated favorable internal consistency. ConclusionsOverall knowledge, attitude, and belief scores were modest in this sample. Higher knowledge and attitude scores were observed for some types of ACS information exposure, supporting the importance of future educational efforts in this population.

Different doses of hyaluronic acid injections in patients with knee osteoarthritis: A multicenter, randomized, prospective, single-blind, clinical study.

Many formulations and dosing regimens are available for hyaluronic acid (HA). To compare different doses of linear, high-molecular weight (HMW) HA injections among patients with knee osteoarthritis (OA). Hundred patients were included in this randomized, single-blinded trial and randomly divided into three HA injection groups. The first group received five weekly 20mg HA injections, the second group received three weekly 32mg HA injections, and the third group received a single 48mg HA injection. Patients were evaluated at baseline, 1, 3, and 6months after the last injection for pain, stiffness, and function using the visual analog scale (VAS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire. Quality of life, patient's global assessment, and Timed Up and Go (TUG) test scores were also evaluated. There was significant improvement in the WOMAC, VAS-pain, quality of life, patient's global assessment, and TUG test mean scores at all follow-up time points (p< 0.001). However, the groups showed no significant differences in WOMAC, VAS-activity pain, and patient global scores at any follow-up point. Intra-articular injections of different doses of linear HMW HA can improve pain, stiffness, function, and quality of life in patients suffering from knee OA over a six-month period.

Evaluating Effectiveness of Group Intervention Working on Executive Function for Children with Attention Deficit Hyperactivity Disorder: A Prospective Observational Cohort Study

Introduction: The objective of this study is to evaluate the effectiveness of Simon says program (SSP), a strategy-based group intervention program working on executive function (EF) for children with attention deficit hyperactivity disorder (ADHD). Methods: A prospective observational cohort study was conducted from December 2021 to July 2022 recruiting 21 SSP participants, either they were on stimulant or not on stimulants, and 12 other ADHD patients who are on stimulant medication only without prior participation in SSP, using convenience sampling method, from Child Development Clinic Hospital Sultan Ismail. NICHQ Vanderbilt Assessment Follow Up Scales (VAS) were used to measure its effectiveness and the significance of score differences before and after SSP were assessed using paired sample t-test of Statistical Package for Social Science (SPSS) version 28.0 software. Results: Total of 33 children participated in the study. From our study, only those participants on behavioural therapy alone showed statistically significant reduction in inattentive score, hyperactivity score and total symptoms score at the third month and sixth month after joining SSP from parents-rated VAS. There were no statistically significant differences in the average VAS performance score for both groups. Conclusion: SSP could be an effective behavioral intervention for children with ADHD children. Limitations included lacking clear generalizability due to the convenience sampling method and potential inter-rater variability.

784 Effects of Optimal Versus Suboptimal Median Household Income on the Operative Traumatic Brain Injury Population: A Propensity Score-matched Analysis

INTRODUCTION: Median household income is a useful metric for healthcare disparity assessment. New England holds a highly diverse, densely populated metropolitan area with one of the highest living wages in the US. To our knowledge, there is no published data on the effects of optimal vs. suboptimal median household income on the operative traumatic brain injury (TBI) patients. METHODS: Demographic, clinical and outcome data of operative TBI patients between 2015 and 2021 were collected and stratified based on optimal (80 000$ or more) and suboptimal (less than 80 000$) median residential household income. 1:1 tight caliper (0.01) propensity score matching was performed to balance the groups for comparative analysis. RESULTS: From the initial 91 patients in the optimal and 102 patients in the suboptimal income groups, 62 patients were included in each group after propensity matching. There were significantly more ethnic minority patients in the suboptimal as compared to the optimal income group (66.1% and 35.7%, respectively; p=0.002). Optimal income group patients presented as transfers from other hospitals significantly more frequently than the suboptimal group (52.5% and 30.7%, respectively; p = 0.02). There were no significant differences in post-operative Glasgow coma scale scores (p = 0.15), modified Rankin scale scores at discharge (p = 0.92) and upon follow-up (p = 0.1), mortality (p &gt; 0.999) or disposition destination distribution (p = 0.3). CONCLUSIONS: While the suboptimal income group is significantly more ethnically diverse, optimal versus suboptimal median household income does not seem to affect TBI outcomes and disposition. Optimal income group patients are more frequently presenting as transfers from other facilities indicating fair high-level care at a specialized high safety-net burden trauma center adapted to an ethnically diverse population.

Anthropometric knowledge and measurement evaluation among female volunteer community health workers in Depok

&lt;p&gt;&lt;strong&gt;Background&lt;/strong&gt;: At the community level, assessment for children nutritional status is measured by female volunteer community health workers (FVCHW) through integrated health post (Posyandu). Based on initial observation, volunteers have sufficient knowledge of anthropometric measurement however, to put it into practice, common pitfalls remain found.Refreshment on basic knowledge and practical training on anthropometric assessment is needed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objectives&lt;/strong&gt;: As part of Kampung Caraka Project that attempts to empower locals to be deliberately aware of community health and well-being, this particular study aims to evaluate knowledge of FVCHW as well as their accuracy and precision on anthropometric assessment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods&lt;/strong&gt;: This study is a quasi-experimental study with pre-posttest with control group design. The sample was purposively selected and 54 overweight adolescents were divided into a control group and two intervention groups. Education using healthy snacks quartet was conducted for 21 days from September to October 2023 in Makassar City. Data analysis was performed using Wilcoxon singed ranks test.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results&lt;/strong&gt;: Results showed women with good precision for MUAC, height, head circumferences and length measurement were 23.1%, 23.1%, 53.8% and 33.3%, respectively. In contrast, only 7.7% of women had good accuracy on MUAC measurement. There is a significant difference of knowledge score before and after the education given (p-value 0.02, CI 95%).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions&lt;/strong&gt;: The cadre had good precision yet poor accuracy, implying the necessity of standardized procedure and regular equipment calibration prior to anthropometric measurement. There is a difference in mean scores before and after the education given, yet still denoted as low capacity. Further comprehensive education is highly required. &lt;/p&gt;

Effect of Murrotal Al-Qur’an Audio on First Stage Labor Pain among Maternity Women

The purpose of this study is to determine the effect of Murrotal Al-quran Audio on first stage labor pain among maternity women in Prof. dr. J. A Latumeten Hospital Maluku Province, Indonesia. The study design is quasy experimental. The population is all maternity women who were in the first stage labor in Januari 2022 which consisted of 68 women. 30 women were selected purposively and agreed to join the study. The inclusion criteria are muslim women who had no hearing problems and labor complication. The intervention was an audio of Murrotal Al-quran Surah Ar-Rahman for 30 minutes. A numeric rating scale was used to measure the pain level before and after intervention. The bivariate analysis was done by Mann Whitney test. The results show that majority of women (60%) experienced a moderate level of pain before and after intervention in the control group. While, in the experiment group, majority of women (60%) experienced moderate level of pain before intervention and majority of them (66,6%) experienced mild level of pain after intervention. The bivariate analysis shows that there was a significant difference of pain score between experiment and control group after intervention (p= .005). In addition, there was a significant difference of pain score before and after intervention in the experiment group (p= .005). There was an effect of Murrotal Al-quran Audio on first stage labor pain among maternity women in Prof. dr. J. A Latumeten Hospital Maluku Province, Indonesia in 2022. The Murrotal Al-quran Audio is effective to decrease labor pain among maternity women. Nurses and midwives who work in the labor room are urged to implement the murroral Al-quran Audio to help maternity women in decreasing labor pain.

Lower limb explosive power and dynamic stability in soccer referees and assistant referees

Background: Elite referees make more than 1,400 changes of action and up to 500 changes of direction in a match, which places a high demand on the explosive power of lower limbs. Lower limb injuries are a common problem for soccer referees and have a negative impact on their performance in a match. The purpose of the study was to assess the explosive power and dynamic stability of soccer referees from the viewpoint of refereeing function. Methods: The research sample consisted of 26 soccer referees, including 13 head referees and 13 assistant referees. The following jump tests were administered to determine the referees’ lower limb explosive power: the countermovement jump test (CMJ), the countermovement jump test with free arms (CMJ FA), the squat jump (SJ), and a 10-second vertical jump test. The level of dynamic stability was diagnosed by the Y Balance test. Results: Compared to assistant referees, head referees reached higher levels of explosive power in all measured parameters but the differences were not statistically significant. For the level of dynamic stability, we observed significant differences in the composite score and % lower limb length in favor of the referees in the posteromedial and posterolateral directions for the left and right legs. Conclusions: The greatest differences were found in dynamic stability, specifically in the composite score and % lower limb length in the posteromedial and posterolateral direction. The differences may be caused by typical movement patterns associated with these two adjudicatory roles. We recommend the inclusion of compensatory exercises in the training of assistant referees.

Efficacy of Intra-Articular Corticosteroid Injection for Nonsurgical Management of Trapeziometacarpal Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

As osteoarthritis (OA) of the trapeziometacarpal (TMC) joint leads to a high degree of disease burden with compromises in rudimentary and fine movements of the hand, intra-articular injections may be a desirable treatment option. However, because there are no evidence-based guidelines, the choice of intra-articular injection type is left to the discretion of the individual surgeon in collaboration with the patient. The purpose of our study was to perform a systematic review and meta-analysis using level I studies to compare outcomes following corticosteroid and alternative methods of intra-articular injections for the management of TMC OA. Our hypothesis was that intra-articular corticosteroid injections were no more effective than other methods of intra-articular injections for the management of TMC OA. A systematic literature search was performed. Eligible for inclusion were randomized control trials reporting on intra-articular corticosteroid injection for the management of TMC OA. Clinical outcomes were recorded. The 10 included studies comprised 673 patients. The mean age was 57.8 ± 8.3 years, with a mean follow-up of 6.4 ± 2.7 months. There was no significant difference in visual analog scale scores, grip strength and tip pinch strength between corticosteroids and hyaluronic acid at short- and medium-term follow-up. Further, there was no difference in visual analog scale pain scores at rest at medium-term follow-up between corticosteroids and platelet-rich plasma. Despite short-term improvement with intra-articular corticosteroid injections, there was no significant difference in pain and functional outcomes following intra-articular corticosteroid injections compared to hyaluronic acid or platelet-rich plasma administration. Given the affordability, ease of administration, and efficacy associated with corticosteroids, they are a favorable option when considering the choice of intra-articular injection for the management of TMC OA. Therapeutic II.

Juvenile Myasthenia Gravis in North Texas: Clinical Features, Treatment Response, and Outcomes

BackgroundJuvenile myasthenia gravis (JMG) is a rare autoimmune disease that causes fatigable muscle weakness in children aged <18 years. There is currently no curative treatment or internationally accepted standard of care for JMG. The objective is to investigate relationships between clinical presentation, antibody status, severity of disease onset, electrodiagnostic evaluation, and response to therapy in JMG. MethodsThis study was a retrospective chart review. Congenital myasthenic syndromes were excluded. Data on demographics, treatments, and outcomes were collected. Disease severity was evaluated using Myasthenia Gravis Foundation of America (MGFA) clinical classifications. ResultsWe identified 84 patients with JMG at Children's Medical Center Dallas between January 2014 and February 2022. It was found that 52% of patients presented with ocular JMG (median onset age 4.5 years) and 48% with generalized JMG (median onset age 11.5 years); 81% tested positive for acetylcholine receptor antibodies. Patients were 17% non-Hispanic white, 29% Hispanic, 39% black, and 12% Asian. There was a significant difference in average MGFA scores between ethnicities (P = 0.047) and age groups (P = 0.004), with postpubertal patients having higher average MGFA scores than prepubertal patients. Seventy-one percent of patients who underwent thymectomy experienced a decrease in MGFA scores postprocedure. ConclusionsOur study showed that there were significant differences in disease severity between ethnicities and age groups and that most patients who underwent thymectomy showed clinical improvement. These outcomes highlight the need for additional therapies in the treatment of JMG and the importance of extending clinical trials to the pediatric population.

A Study to Assess the Effectiveness of Video Assisted Teaching on Knowledge and Attitude of Adolecsent Regarding Healthy Food Habits in Selected School of D&amp;NH

Background: The world health organization (WHO) defines an adolescent as any person between ages 10–19. During adolescent various physiological changes occurs as a result, nutritional requirement of the body increase tremendously, therefore important to consume a balance diet at this stage. In adolescent various health problem occur such as reproductive health problems, nutritional health problem, psychosocial problem etc., but due to poor intake and availability of diet major health problem is under nutrition or over nutrition. Adolescent especially school going children are most vulnerable towards the problem like undernutrition or obesity and when they grow in age this adverse health tendency continues to persist and impairs the health and wellbeing of adolescent population and increase the risk of type 2 diabetes, cardiovascular disease, non-alcoholic fatty liver disease and some cancer. Aim: The aim of the study was to assess the effectiveness of video assisted teaching on healthy food habits among adolescents. Methodology: In this study, pre-experimental research design was used. For total 100 adolescents who met the sampling criteria were selected with Simple random sampling technique from the selected school of D&amp;NH. The data were collected using structure knowledge questionnaire and attitude scale. Results: The result revealed that a significant difference in the mean pre-test knowledge score (9.13) and the mean post-test knowledge score (17.08) of adolescent after administering of video assisted teaching as measured by ‘t’ test (27.248) which was highly significant at 0.001 level of significance. It shows that there was significant difference in mean attitude pre-test score (42.87) and post-test attitude score (49.17) of adolescents, the ‘t’ test measured (11.815) which shows highly significance at 0.001 level of significance. There is no association between pre-test knowledge and attitude with selected demographic variable. Only gender shows that Significant association with selected demographic variable.

Abstract P200: Mediterranean Diet and Metabolic Syndrome in Adolescents: An Analysis From the National Health and Nutrition Examination Survey 2015-2020

Background: The Mediterranean Diet (MD) is an evidence-based dietary approach emphasizing fruits, vegetables, whole grains, seafood, and olive oil. While it’s demonstrated efficacy in enhancing cardiometabolic health in adults, it’s received minimal evaluation in adolescents with metabolic syndrome (MetS). Hypothesis: We hypothesized that higher consumption of MD foods was associated with better metabolic health in a nationally representative sample of U.S. adolescents. Methods: A secondary analysis was conducted using data from the National Health and Nutrition Examination Surveys 2015-2020 (pre-COVID) in adolescents (12-19 years) with ≥ 2 valid 24-hour dietary recalls, complete fasting data for all components of the International Diabetes Foundations definition of MetS risk factors, and no known diabetes. Consumption of MD foods was evaluated using the validated, literature-based MD intake score (Medi-Lite, 0-16 score, excluding alcohol). MetS was evaluated using a continuous MetS score (cMetS) and separated into quartiles [Q1, metabolically unhealthy (cMetS score 1.83 ± 1.64) vs. Q4, metabolically healthy (cMetS score -4.16 ± 0.89)]. Correlation of Medi-Lite scores with cMetS scores and quartile groups controlled for energy intake, age, sex, and BMI were assessed via Pearson correlation and odds ratios, respectively. Results: The primary analyses included 886 adolescents (~15 years, 49% female, 70% non-Hispanic, body mass index ~25 kg/m 2 ) with a mean cMetS score of -1.40 ± 2.39. In the total sample, overall consumption of the MD was low (mean score 6.95 ± 1.83) and cMetS scores were not associated with Medi-Lite scores (r = -0.05, p = 0.21). There was a significant between-group difference for Medi-Lite scores between quartiles (F = 1.69, p = 0.05). In the metabolically healthy group, there was a positive trend towards between cMetS score and Medi-Lite score (r = 0.15, p = 0.06). No correlation was found between cMetS and Medi-Lite scores in the metabolically unhealthy group (r = -0.04, p = 0.59). Metabolically healthy adolescents had higher odds of consuming the MD compared to metabolically unhealthy adolescents (OR 2.012, 95% CI 1.44 to 2.81, p &lt; 0.001). Conclusion: In conclusion, U.S. adolescents had an overall low consumption of MD foods. Metabolically healthy adolescents consumed more MD foods compared to metabolically unhealthy adolescents. Future research should evaluate a MD lifestyle intervention as a treatment option for adolescents with MetS.

No significant difference in thick versus thin osteochondral flap trochleoplasty in the treatment of trochlear dysplasia: A systematic review.

Trochleoplasty has become increasingly utilised to address patellar instability in the setting of severe trochlear dysplasia. There remains a paucity of literature on the outcomes of 'thick'- versus 'thin'-osteochondral flap trochleoplasty. The purpose of this study is to compare clinical and radiographic outcomes between patients with patellar instability with symptomatic trochlear dysplasia treated using a 'thick' versus 'thin' osteochondral flap trochleoplasty. A systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using a PRISMA checklist. Quality assessment of final articles was conducted by two blinded reviewers. Articles were separated based on the use of a 'thick' versus 'thin' flap trochleoplasty. Data collection consisted of recording the following variables: patient demographics, indications for trochleoplasty, mean follow-up time, additional procedures performed during trochleoplasty, patient-reported outcome measures (PROMs), radiographic outcomes (tibial tubercle-trochlear groove [TT-TG] distance, Caton-Deschamps Index [CDI] and sulcus angle [SA])and the incidence of any postoperative complications and patellar redislocation rates. A total of 24 studies, consisting of 927 patients, were identified as meeting inclusion criteria. A total of five papers described a 'thick' flap technique, while 19 papers described the use of a 'thin' flap technique. No significant difference in the mean improvement of Kujala scores was appreciated when comparing 'thick' versus 'thin' techniques (p > 0.05). Improvements in mean radiographic outcomes based on TT-TG, CDI and SA were observed in both 'thick' and 'thin' flap trochleoplasty groups. The overall redislocation rate was 0.35%. No significant difference in Kujala scores was observedin patients undergoing trochleoplasty utilising 'thick' versus 'thin' technique, while improvements in mean TT-TG, CDIand SA were noted in both technique groups, with an overall redislocation rate of 0.35%. Level IV.

Evaluating the efficacy of OralDETECT training: Face-to-face versus online delivery in dental education.

This study evaluated the effectiveness of face-to-face (F2F) and online OralDETECT training programme in enhancing early detection skills for oral cancer. A total of 328 final-year dental students were trained across six cohorts. Three cohorts (175 students) received F2F training from the academic years 2016/2017 to 2018/2019, and the remaining three (153 students) underwent online training during the Covid-19 pandemic from 2019/2020 to 2021/2022. Participant scores were analysed using the Wilcoxon signed rank test, the Mann-Whitney test, Cohen's d effect size, and multiple linear regression. Both F2F and online training showed increases in mean scores from pre-test to post-test 3: from 67.66 ± 11.81 to 92.06 ± 5.27 and 75.89 ± 11.03 to 90.95 ± 5.22, respectively. Comparison between F2F and online methods revealed significant differences in mean scores with large effect sizes at the pre-test stage (p < 0.001), while significant differences with small effect sizes were noted for post-test 1 (p = 0.002) and post-test 3 (p = 0.041). Regression analysis indicated that the delivery method is associated with the participants' final scores. F2F and online versions of the OralDETECT training programme significantly enhance participants' knowledge and skills in oral cancer detection. Although F2F appeared to be more effective, the difference was not substantial enough to be considered educationally meaningful.

A clinical study on cognitive dysfunction in depressed patients

ABSTRACT Background: Major depression is a commonly occuring, seriously impairing, and often recurrent mental disorder. Depression and cognitive impairement have enormous implications for public health. Cognitive symptoms represent one of the core features of depression and have an impact on many functional outcomes. Different cognitive domains such as attention and concentration, psychomotor speed, executive functioning, and memory have been found to be implicated. Aim: This study aimed at assessing the cognitive domains affected and severity of cognitive dysfunction in first-episode patients of the unipolar depressive episode without psychosis and to assess the correlation of association of severity of cognitive deficit with severity of depression. Materials and Methods: A total of 40 patients with depression diagnosed according to International Classification of Diseases Research Diagnostic Criteria and 40 healthy controls were included. PGI Battery of Brain Dysfunction, Frontal Assessement Battery, and Hamilton Depression Rating scale (HAM–D) were adminstered, and analysis was done using Chi-square test, unpaired t-test, and Pearson’s correlation. Results: The study revealed significant differences in the dysfunction scores between the study and control populations. In the study group, more than 80% of patients had cognitive dysfunction and a positive correlation was found between dysfunction and HAM–D scores. Conclusion: Depression is associated with significant disturbance in cognitive functioning, and the cognitive dysfunction increases with an increase in the severity of depression.