Significant Amount Of Variance Research Articles

Food Insecurity and Blood Pressure in a Multiethnic Population.

Food insecurity is a social determinant of health and is increasingly recognized as a risk factor for hypertension. Native Hawaiians bear a disproportionate burden of hypertension and known risk factors. Despite this, the relative effects of food insecurity and financial instability on blood pressure have yet to be investigated in this population. This study examines the relative effects of food insecurity and financial instability on blood pressure, controlling for potential confounders in a multiethnic sample. Participants (n = 124) were recruited from a U.S. Department of Agriculture-funded study called the Children's Healthy Living Center of Excellence. Biometrics (i.e., blood pressure, weight, and height) were measured. Demographics, physical activity, diet, psychosocial variables, food insecurity, and financial instability were assessed via self-report questionnaires. Hierarchical linear regression models were conducted. Model 1, which included sociodemographic variables and known biological risk factors, explained a small but significant amount of variance in systolic blood pressure. Model 2 added physical activity and daily intake of fruit, fiber, and whole grains, significantly improving the model. Model 3 added financial instability and food insecurity, further improving the model (R2 = 0.37, F = 2.67, p = 0.031). Food insecurity, female sex, and BMI were significantly and independently associated with increased systolic blood pressure. These results suggest a direct relationship between food insecurity and systolic blood pressure, which persisted after controlling for physical activity, consumption of fruits, fiber, and whole grains, and BMI. Efforts to reduce food insecurity, particularly among Native Hawaiians, may help reduce hypertension in this high-risk population.

Relationships Between Lower Extremity Power and Fastball Spin Rate and Ball Velocity in Professional Baseball Pitchers.

Wong, R, Laudner, K, Amonette, W, Vazquez, J, Evans, D, and Meister, K. Relationships between lower extremity power and fastball spin rate and ball velocity in professional baseball pitchers. J Strength Cond Res 37(4): 823-828, 2023-Lower extremity power has been hypothesized to increase ball spin and velocity during pitching in baseball. Therefore, the purpose of this study was to determine the relationship between lower extremity power and fastball spin rate in professional baseball pitchers. A secondary purpose was to determine the relationship between lower extremity power and ball velocity. Fifty-three asymptomatic professional pitchers participated (24.5 ± 3.6 years; 189.9 ± 6.1 cm; 92.6 ± 10.3 kg). Each athlete performed 3 separate bilateral jump tests on force plates: countermovement jump (CMJ), squat jump (SJ), and drop jump (DJ). The average fastball spin rate and ball velocity for each pitcher was calculated using a 3-dimensional Doppler radar and video system over the course of a competitive season. Standard multiple regression analyses ( p ≤ 0.05) revealed significant relationship between ball spin and summation of variables for the CMJ (peak force, peak power, rate of power development, and jump height) ( R2 = 0.20, F = 3.1, p = 0.03). However, no individual variable was significantly associated ( p > 0.09). There was also a significant amount of variance in ball spin explained by summation of variables for the SJ (peak force, peak power, rate of power development, and jump height) ( R2 = 0.19, F = 2.8, p = 0.04); rate of power development was the only variable that significantly predicted ball spin within this model ( B = 0.27; 95% confidence interval [CI]: 0.003-0.75, p = 0.05). Ball spin was not associated with summation of DJ variables (peak power, rate of power development, jump height, reactive strength index, and total peak power in watts) ( R2 = 0.18, F = 2.0, p = 0.09). For ball velocity, there were no significant relationships for the summation of either the CMJ variables ( R2 = 0.10, p = 0.28) or the SJ variables ( R2 = 0.07, p = 0.44). However, there was a significant amount of variance in ball velocity explained by summation of variables for the DJ ( R2 = 0.30, F = 3.93, p = 0.005). The reactive strength index was the sole unique contribution to this model ( B = 1.18; 95% CI: -10.34 to 2.36, p = 0.002). These findings highlight the relevance of increased lower extremity power on increasing fastball spin rate and ball velocity.

Using wearables to promote physical activity in old age : Feasibility, benefits, and user friendliness.

BackgroundWearables provide new opportunities to promote physical activity also among older adults but data on effectiveness and user friendliness are rare.ObjectiveThe effects of a comprehensive self-regulative intervention on moderate to vigorous physical activity (MVPA) and number of steps were examined using commercially available activity trackers. Acceptance regarding the devices was analysed in various domains.MethodsIn this study 80 older adults (mean = 67.03 years, standard deviation = 3.97 years; 59% women) wore a Fitbit Charge HR for 21 days including a baseline, a postintervention and a follow-up week. The intervention comprised feedback, goal setting and planning and 50% of the participants were additionally randomized to a role model component. Social cognitive predictors based on the health action process approach (HAPA) and user experience were assessed via questionnaires.ResultsThe MVPA increased by an average of 19 min per week and steps by 1317 per day. An additional benefit of the role model component could be observed for MVPA. In the follow-up, the intervention effect was still significant for the number of steps, while MVPA dropped back to baseline. Multilevel models including HAPA variables explained small but significant amounts of variance in MVPA (8% within-person, 26% between-person) and steps (11% within-person, 12% between-person). User experience was rated as very high.ConclusionProviding an intervention based on established behavior change techniques and self-monitoring via wearables seems to be effective for increasing physical activity among older adults. The HAPA variables seem to play a limited role to explain activity levels. Acceptance of wearables can be expected to be high.Supplementary InformationThe online version of this article (10.1007/s00391-022-02083-x) contains supplementary material, which is available to authorized users.

Social justice development among emerging adult students: The influence of families, peers, and religious congregations

ABSTRACT Social justice development is likely influenced by a range of contextual experiences. We examined the ways in which emerging adult students’ experiences with families, peers, and religious congregations were associated with their own social justice outcomes. Participants (N = 288; 65.4% = women) completed a survey of social justice attitudes, beliefs, and perceptions of their families’, peers,’ and congregations’ engagement with social justice issues. Findings indicated that family, peer, and congregational factors explained significant amounts of variance in students’ social justice outcomes and provided unique insight into aspects of students’ experiences that may be particularly relevant to social justice development during this period.

Exercise Identity and Its Relation to Self-Presentation Concerns in Males and Females

ABSTRACT Purpose: It has been determined that exercise identity is a key component of the self-concept and is a strong determinant of exercise behaviors. The purpose of the present study was to examine exercise identity’s relationship with three key self-presentational variables: self-presentational efficacy, social physique anxiety, and impression motivation. Methods: We looked at how exercise identity contributed uniquely to predicting exercise behavior over and above these self-presentational concerns for both males 10 (n = 140) and females (n = 234) recruited from two university communities. Participant’s age ranged from 18–68 years, the majority identified as students, and as Caucasian. Results: The analyses demonstrated that exercise identity was positively correlated with self-presentational efficacy and unrelated to social physique anxiety in both genders. Further analyses revealed that exercise identity contributes a significant amount of variance toward exercise behavior over and above what is accounted for by self-presentational efficacy, social physique anxiety, and impression motivation. Lastly, exercise identity did not moderate the social physique anxiety-exercise relationship in either gender. Conclusion: These findings advance our knowledge of exercise identity and its relationship with various important constructs has been determined that exercise identity is a key component of the self-concept and is a strong determinant of exercise behaviors.

Factors Impacting Functioning Level of Cancer Survivors in Turkey

The purpose of this study was to investigate the relationships between demographic variables, personal factors, impairment-related variables, and functioning levels of cancer survivors in Turkey. Data for this study were collected from a major oncology institute and a nonprofit cancer organization in Turkey. Hierarchical regression analyses were conducted to investigate the sequential effect of demographic variables (i.e., age, gender, income, and education), personal factors (i.e., core self-evaluations, purpose in life, and religiosity), and impairment-related variables (i.e., pain, fatigue, perceived stress, and sleep disturbance) on the functioning level of Turkish cancer survivors (i.e., physical functioning, role functioning, emotional functioning, cognitive functioning, and social functioning). The results indicated that impairment-related variables explained a significant amount of variance in functioning scores above and beyond demographic and personal factors. Pain intensity and perceived stress were most prominent factors impacting functioning levels of Turkish cancer survivors. Pain and stress self-management training, psychotherapy and counseling, physical activity and exercise, and cognitive remediation training are recommended interventions to increase the functioning level and well-being of cancer survivors.

The positive-negative mode link between brain connectivity, demographics and behaviour: a pre-registered replication of Smith et al. (2015).

In mental health research, it has proven difficult to find measures of brain function that provide reliable indicators of mental health and well-being, including susceptibility to mental health disorders. Recently, a family of data-driven analyses have provided such reliable measures when applied to large, population-level datasets. In the current pre-registered replication study, we show that the canonical correlation analysis (CCA) methods previously developed using resting-state magnetic resonance imaging functional connectivity and subject measures (SMs) of cognition and behaviour from healthy adults are also effective in measuring well-being (a ‘positive–negative axis') in an independent developmental dataset. Our replication was successful in two out of three of our pre-registered criteria, such that a primary CCA mode's weights displayed a significant positive relationship and explained a significant amount of variance in both functional connectivity and SMs. The only criterion that was not successful was that compared to other modes the magnitude of variance explained by the primary CCA mode was smaller than predicted, a result that could indicate a developmental trajectory of a primary mode. This replication establishes a signature neurotypical relationship between connectivity and phenotype, opening new avenues of research in neuroscience with clear clinical applications.

The Transdiagnostic Role of Rumination in the Comorbidity of PTSD and Depression

Post-traumatic stress disorder (PTSD) and major depressive disorder (MDD) are highly comorbid. Common factors that exist in both disorders could explain disorder co-occurrence. In the present study, we examined the role of rumination as a potential shared factor within PTSD and MDD in a sample of military personnel deployed in armed conflict areas. Confirmatory factor analyses were conducted for PTSD and MDD separately and then controlling for rumination. Results indicated that a significant amount of variance between PTSD and depression, both at the item- and factor-level, could be explained by rumination. Findings indicate that rumination, as a transdiagnostic mechanism present in both PTSD and MDD, could account for disorder comorbidity.

Actigraphy-Based Associations Between Chronotype and Physical Activity in Older Adults

Housing insecurity, or limited/unreliable access to quality housing, is a powerful chronic stressor that can negatively affect individual health and well-being. This study extends prior research by examining the effect of multiple forms of housing insecurity on both the mental and physical health of aging adults using the Midlife in the United States study (MIDUS; N = 2532; M age = 63.42; 57% women; 16% black). Participants reported on experiences of anxiety/depression in the past year, number of chronic health conditions experienced in the last year, and experiences of housing insecurity since the 2008 recession (e.g., homelessness, threatened with foreclosure or eviction, missed rent or mortgage payment). 14% of participants reported experiencing one or more housing insecurity events in the aftermath of the recession. Higher levels of housing insecurity were experienced by midlife participants (ages 46-65) and black participants. Regression results showed that, even when controlling for prior health, housing insecurity was significantly associated with higher odds of experiencing anxiety/depression and additional chronic health conditions. These results suggest that housing insecurity experiences are fairly prevalent among midlife and aging adults, and that housing insecurity experiences leave these adults susceptible to compromised mental and physical health. This work has various implications for policy around addressing housing access and affordability issues for aging adults as a public health concern. Subsequent analyses will examine age, gender, and race/ethnic differences in these associations between housing insecurity and health outcomes.

Actigraphy-Based Associations Between Chronotype and Physical Activity in Older Adults

Chronotype is a measure of the time of day people prefer to be most active or to sleep. There is a known relationship between chronotype and engagement in physical activity in young and middle-aged adults, such that individuals with a morning chronotype engage in more physical activity compared to those with an evening chronotype. Our study aimed to replicate this finding in an older adult sample. Actigraphy can be used to measure both physical activity and sleep. Because of its ability to capture information about bedtime and arise time, actigraphy can serve as an objective measurement of chronotype. Participants were 159 older adults (ages 60-89, M = 74.73) who wore an ActiGraph GT9X on their non-dominant wrist for 7 days in a free-living environment. Chronotype was measured continuously using the midpoint of the ActiGraph-calculated sleep interval. We used multiple regression to determine the relationship between physical activity and chronotype adjusting for sex, age, and body mass index. Results suggest that while these variables explain a significant amount of variance in physical activity, R2 = 19.0%, F (4, 152) = 8.921, p < .001, there is no significant relationship between chronotype and total physical activity in our sample, ß= -.117, p = .114. These findings are inconsistent with what has been shown in younger samples and suggest that the relationship between chronotype and physical activity may change as one ages. Future research should consider whether particular physical activity intensities (vs. total activity) may have a relationship with chronotype in older adults.

Theory of planned behavior and college student 24-hour dietary recalls

Objective: The transition to college is marked by poorer eating behaviors, making emerging adulthood a particularly salient intervention point for improving lifelong health. The present study aims to better understand what psychosocial factors predict eating behaviors of college students using the Theory of Planned Behavior (TPB). Participants & Methods: Dietary recalls were analyzed the Healthy Eating Index (HEI)-2015 scoring system for 67 university students between the ages of 18 and 25 (70.1% female; 49.3% White, 20.9% Black/African American, 13.4% Asian). Results: Haye’s PROCESS Model 6 was used. The full model accounted for a significant amount of variance in HEI-2015 scores (F[3, 63] = 3.09, p = .033, R2 = .12). The final model suggested a significant indirect effect of PBC on the relation between ATT and HEI-2015 (β = .859, SE = .637, 95% CI [.009, 2.482]). Conclusions: Although some college students might have favorable attitudes, only those who believe this is within their control actually ate a (somewhat) healthier diet.

Assessment of Alzheimer's disease polygenic risk score on longitudinal amyloid accumulation in cognitively intact older adults.

We investigated whether an Alzheimer's disease (AD) polygenic risk score (PRS) could predict longitudinal brain amyloid accumulation in cognitively intact older adults participating in the Flemish Prevent AD Cohort KU Leuven (F-PACK). Previously published data have highlighted associations between AD susceptibility loci and AD-related brain changes. Sixty-one cognitively healthy F-PACK participants (median age: 68 (56-79), 29 females, 29 APOE ε4 carriers) received an [18 F]Flutemetamol-PET scan and structural MRI at baseline and follow-up (average time interval 4.6 years (3.4-8.6)). Amyloid rate of change was defined as absolute change divided by time interval. Participants were genotyped using the Illumina GSA and imputed using the Michigan server and HRC reference panel. Data were quality controlled using PLINK(v1.9, http://pngu.mgh.harvard.edu/purcell/plink/, Purcell et al., 2007) (minor allele frequency >0.01). PRS calculation was performed using PRSice(Choi & O'Reilly, 2019) with the Stage 1 summary statistics (containing SNP p-values and corresponding effect sizes) from the GWAS performed by Kunkle et al.,(2019). European individuals from the 1000 Genomes dataset were used for clumping (N=503). We calculated PRSs at three thresholds for SNP inclusion: pT=0.5(Escott-Price et al., 2015); 1x10-5 ; 5x108 . A Mann-Whitney U-test was used to determine amyloid rate of change differences between APOE ε4 carriers and non-carriers. Linear models were used to assess if the PRS could predict changes in amyloid, with age, sex and the first three principal components from the PRS calculation as covariates, at each of the p-value thresholds for SNP inclusion. APOE ε4 carriers showed a trend towards a significantly higher rate of change than non-carriers (U=459.5, p=0.056). When predicting amyloid rate of change, the linear model outputs were similar when the thresholds for SNP inclusion were pT=1x10-5 and 5x10-8 . Although models did not reach significance, there was a significant effect of PRS on amyloid rate of change: pT=1x10-5 : β=0.0056 (CI: 0.0000785-0.011), p<0.05; pT=5x10-8 : β=0.0054 (CI: 0.000042-0.011), p<0.05. PRS was not a significant predictor for amyloid accumulation when the threshold for SNP inclusion was pT=0.5: β=0.0013 (-0.004-0.007), p>0.05. PRSs calculated with a SNP inclusion threshold of pT=1x10-5 or 5x10-8 explain a small but significant amount of variance in amyloid accumulation in cognitively intact older adults.

Resting-state functional heterogeneity of the right insula contributes to pain sensitivity

Previous studies have described the structure and function of the insular cortex in terms of spatially continuous gradients. Here we assess how spatial features of insular resting state functional organization correspond to individual pain sensitivity. From a previous multicenter study, we included 107 healthy participants, who underwent resting state functional MRI scans, T1-weighted scans and quantitative sensory testing on the left forearm. Thermal and mechanical pain thresholds were determined. Connectopic mapping, a technique using non-linear representations of functional organization was employed to describe functional connectivity gradients in both insulae. Partial coefficients of determination were calculated between trend surface model parameters summarizing spatial features of gradients, modal and modality-independent pain sensitivity. The dominant connectopy captured the previously reported posteroanterior shift in connectivity profiles. Spatial features of dominant connectopies in the right insula explained significant amounts of variance in thermal (R2 = 0.076; p < 0.001 and R2 = 0.031; p < 0.029) and composite pain sensitivity (R2 = 0.072; p < 0.002). The left insular gradient was not significantly associated with pain thresholds. Our results highlight the functional relevance of gradient-like insular organization in pain processing. Considering individual variations in insular connectopy might contribute to understanding neural mechanisms behind pain and improve objective brain-based characterization of individual pain sensitivity.

Self-Compassion, Healthy Lifestyle Behaviors, and Psychological Well-Being in Women

Despite pressures on women to make healthy lifestyle choices and a bevy of constantly changing fitness trends and gadgets, national trends related to women’s health reflect a decline in wellness and serious health disparities based on race and socioeconomic status. Therefore, factors underlying women’s success in adopting and maintaining healthy lifestyle behaviors continue to be an essential area for research in health promotion. Previous studies have preliminarily explored the role of self-compassion in women’s health with regard to exercise and eating although less is known about how these factors contribute to overall psychological well-being. In this study, we investigated the relationships between self-compassion, engagement in healthy lifestyle behaviors, and overall psychological well-being among a sample of 340 adults from diverse backgrounds. Results supported the hypothesis that more self-compassionate women engage more frequently in healthy lifestyle behaviors and experience greater psychological well-being. Engagement in healthy lifestyle behaviors partially mediated the relationship between self-compassion and psychological well-being, such that engagement in healthy lifestyle behaviors explained a significant amount of variance in psychological well-being over and above self-compassion. Participants of underrepresented ethnic and racial groups reported higher levels of self-compassion, and higher socioeconomic status participants reported greater engagement in healthy lifestyle behaviors.

More than Words: A Study of Ethnic Identity, Reading Self-Efficacy, and Reading Practices of Hispanic American and African American Adults

Reading is a basic skill that is needed for academic success and employment opportunity. Aliteracy, or the lack of a reading habit, and lower motivation to read, are problems at the university level, especially among ethnically diverse adults. Reading self-efficacy is associated with reading comprehension, word reading, foreign language learning and the use of reading strategies. Given that ethnic identity has been linked to well-being and an improved sense of competence among minoritized adults, the present study sought to investigate the connection between reading self-efficacy and ethnic identity as well as the reading practices of African American and Hispanic American adults. Results revealed that ethnic identity, ethnicity, and home language explained a statistically significant amount of variance in reading self-efficacy. Similarities and differences in reading choices based on gender were also investigated.

Association Between Components of Cognitive Reserve and Serum BDNF in Healthy Older Adults

Background: The brain-derived neurotrophic factor (BDNF) protein has been shown to have a prominent role in neuron survival, growth, and function in experimental models, and the BDNF Val66Met polymorphism which regulates its expression has been linked to resilience toward the effects of aging on cognition. Cognitively stimulating activity is linked to both increased levels of BDNF in the brain, and protection against age-related cognitive decline. The aim of this study was to investigate the associations between serum BDNF levels, the BDNF Val66Met genotype, and components of cognitive reserve in early and mid-life, measured with the Lifetime of Experiences Questionnaire (LEQ).Methods: Serum BDNF levels were measured cross-sectionally in 156 participants from the Tasmanian Healthy Brain Project (THBP) cohort, a study examining the potential benefits of older adults engaging in a university-level education intervention. Multiple linear regression was used to estimate serum BDNF’s association with age, education, gender, BDNF Val66Met genotype, later-life university-level study, and cognitively stimulating activities measured by the LEQ.Results: Serum BDNF in older adults was associated with early life education and training, increasing 0.007 log(pg/ml) [95%CI 0.001, 0.012] per unit on the LEQ subscale. Conversely, education and training in mid-life were associated with a −0.007 log(pg/ml) [−0.012, −0.001] decrease per unit on the LEQ subscale. Serum BDNF decreased with age (−0.008 log(pg/ml) [−0.015, −0.001] per year), and male gender (−0.109 log(pg/ml) [−0.203, −0.015]), but mean differences between the BDNF Val66Met polymorphisms were not significant (p = 0.066). All effect sizes were small, with mid-life education and training having the largest effect size ( = 0.044).Conclusion: Education in both early and mid-life explained small but significant amounts of variance in serum BDNF levels, more than age or gender. These effects were opposed and independent, suggesting that education at different stages of life may be associated with different cognitive and neural demands. Education at different stages of life may be important covariates when estimating associations between other exposures and serum BDNF.

Grade 12 performance and academic performance in first-year psychology students: Influences of generational status and academic self-concept

We examined the relationship between students’ Grade 12 achievement and their first-year academic performance and the potential moderating and/or mediating roles of generational status and academic self-concept in this relationship. Participants were 203 students (female = 82.8%; black African =73.9%; mean age =19.46 years, SD = 1.36 years). They completed a self-concept scale and self-reported their demographic and academic information. A series of multiple regression analyses were conducted. Results indicated that Grade 12 academic performance explained a significant amount of variance in first-year marks (10.5%). Generational status was not a moderator in the relationship between students’ Grade 12 achievement and their first-year academic performance. Academic self-concept had a main effect on participants’ psychology marks but was neither a mediator nor a moderator. Our findings are consistent with the evidence that academic performance in higher education is dependent on prior academic performance and academic self-concept. There remains a need for studies on contextual factors that would explain the complex interplay of factors that influence the achievement of students in the transition from high school to university.

Evaluating Teacher Language Within General and Special Education Classrooms Serving Elementary Students with Autism

This study examined how teachers and paraprofessionals in 126 kindergarten-second grade general and special education classrooms talked with their 194 students with autism, and further, how individual student characteristics in language, autism symptoms, and social abilities influenced this talk. Using systematic observational methods and factor analysis, we identified a unidimensional model of teacher language for general and special education classrooms yet observed differences between the settings, with more language observed in special education classrooms—much of which included directives and close-ended questions. Students’ receptive vocabulary explained a significant amount of variance in teacher language beyond its shared covariance with social impairment and problem behavior in general education classrooms but was non-significant within special education classrooms. Research implications are discussed.

OMIC-02. COGNITIVE DEFICITS AND ALTERED FUNCTIONAL BRAIN NETWORK ORGANIZATION IN PEDIATRIC BRAIN TUMOR PATIENTS

Pediatric brain tumor survivors experience significant cognitive sequelae from their diagnosis and treatment. The exact mechanisms of cognitive injury are poorly understood, and validated predictors of long-term cognitive outcome are lacking. Large-scale, distributed brain systems provide a window into brain organization and function that may yield insight into these mechanisms and outcomes. We evaluated functional network architecture, cognitive performance, and brain-behavior relationships in pediatric brain tumor patients. Patients ages 8–18 years old with diagnosis of a brain tumor underwent awake resting state functional Magnetic Resonance Imaging during regularly scheduled clinical visits and were tested with the National Institutes of Health Toolbox Cognition Battery. Age- and sex-matched typically developing children were used as controls. We observed that functional network organization was significantly altered in patients compared to controls (p < 0.001), with the integrity of the dorsal attention network particularly affected (p < 0.0001). Moreover, patients demonstrated significant impairments in multiple domains of cognitive performance, including attention (p < 0.0001). Finally, a significant amount of variance (R squared = 0.52, F = 3.2, p < 0.05) of age-adjusted total composite scores from the Toolbox was explained by changes in segregation between the dorsal attention and default mode networks. Our results suggest that changes in functional network organization may provide insight into long-term changes in cognitive function in pediatric brain tumor patients.

The Role of Personality Functioning on Early Drop out in Outpatient Substance Misuse Treatment

Background Treatment initiation is a major factor contributing to positive outcomes, but the supporting literature remains limited. It is difficult to draw conclusions regarding predictors of dropout, and there is a need to target clients’ major early attrition vulnerabilities. Despite empirically validated models for assessing personality, little is known about its role in the treatment process. Studies that have been conducted in this area have focused mainly on stable personality traits and provide conflicting evidence. Aims: The aim of this study is to examine to what extent service users’ personality functioning are potential determinants of early drop out. Methodology: A cross-sectional multi-site design examined the therapy process in a naturalistic setting in 5 outpatient preparation treatment centers with 210 service users. The current study adopts a contemporary dimensional-based framework, similar to the Alternative Model of Personality Disorder of the DSM-V and examines the role of characteristic adaptations (SIPP-118) on early drop out (CEST-Intake). Findings: From the broad spectrum of personality traits, only Depression remained significant predictor of drop out. Higher dysfunctional levels in Social Concordance [OR] = 1.85, Wald =19.87, p =.002, 95% CI [1.1, 1.9] as well as the facets Aggression Regulation, Respect and Purposefulness were also predictors of early drop out, while Treatment Readiness and Desire for Help accounted for a significant amount of variance. Conclusions: These findings extend our knowledge of the predictive role of characteristic adaptations in treatment and suggest it may be important to assess these individual differences early on and to design personalized-informed interventions.