Side Of Vertebral Column Research Articles

Histopathological evaluation of the effect of platelet-rich fibrin on canine cutaneous incisional wound healing

Platelets are a natural source of growth factors and cytokines that promote wound healing, and platelet-rich fibrin contains concentrated growth factors. Growth factors in platelet-rich fibrin may promote wound repair. In this study the effect of platelet-rich fibrin was evaluated in a dog model of cutaneous incisional wounds using histology and semi-quantitative evaluation. A pair of ten-centimeter full-thickness parallel linear cutaneous wounds were created on the backs of 15 dogs on the both sides of vertebral column. On the left side the platelet-rich fibrin clot was applied to the edges of the wound (Treatment group) and the right side received nothing (Control group). All wounds were then closed with 3-0 non-absorbable Nylon suture. The dogs were divided into three groups of five dogs. The wound tissues were sampled by electrosurgery in group one after 3 days, group two after 7 days and group three after 14 days post surgery. For each specimen, histopathological examination and semi-quantitative evaluation was performed by light microscopy using Hematoxylin & Eosin and Masson’s trichrome staining. The results demonstrated that platelet-rich fibrin improved and accelerated cutaneous incisional wound healing.

Bilateral Duplex collecting system in Horse shoe kidney: An unusual association

A 17 years unmarried female presented to Gastroenterology Department of our hospital for nonspecific symptoms of epigastric pain. The Ultrasonographic examination of the patient re-vealed triple kidney with horseshoe anomaly. She was then referred to us for further evaluation. We further proceed with Intravenous Urography (IVU) which demonstrated a bilateral duplex system in a asymmetrical horseshoe kidney (L shaped fusion). Left side kidney was vertically placed while the right side kidney was horizontally placed. One of the moieties was on the right side of vertebral col-umn while the other moiety was overlying the ver-tebra and isthmus was on the left side of vertebra (Figure-1). A contrast enhanced computed tomog-raphy (CECT) scan confirmed the diagnosis of bilat-eral duplex system in horseshoe kidney (Figure-2). As the patient had non-specific, unrelated symp-toms, patient was give symptomatic treatment for the same and was advised regular follow-up. Du-plicated collecting systems (also known as duplex collecting systems) can be defined as renal units containing two pyelocaliceal systems that are as-sociated with a single ureter or with double ureters. The prevalence of Partial duplication is 0.6%, while complete duplication of ureters occurs in 0.2% of live births (1). When a single ureteral bud bifurcates before the ampulla bifurcates, a duplex kidney with a bifid renal pelvis or bifid ureter results (2). Con-genital anomalies of the kidneys include a group of so-called fusion anomalies, in which both kidneys are fused together in early embryonic life. Fusion anomalies of the kidneys can generally be placed into 2 categories: [1] horseshoe kidney and its vari-ants and [2] crossed fused ectopia. Horseshoe kid-ney is probably the most common fusion anomaly. The term horseshoe kidney refers to the appearance of the fused kidney, which results from fusion at one pole. Horseshoe kidney is the most common renal fusion anomaly, the incidence being about 1