This study presents the energy-economic analysis and optimization of a shell and tube heat exchanger. A water-water, segmental baffled shell and tube heat exchanger was designed using the Kern method and analysed by performing energy and economic modelling. The analysis is carried out considering the design variables on the shell side i.e. baffle cut, baffle spacing, shell diameter and tube side variables i.e. tube layout, tube outside diameter, number of tube passes and number of tubes. The multi-objective heat transfer search algorithm was used to optimize the heat exchanger for minimum total cost and maximum heat exchanger efficiency. Multiple optimal solutions were presented using the Pareto optimal curve. TOPSIS selection criteria was used to identify the optimum operating condition. Within the given bounds of the variables, the shell and tube heat exchanger can be operated at a minimum cost of 72,000 $/year resulting in 16.4 % efficiency, or, it can be operated at a maximum efficiency of 81.6 % with a total cost of 275,000 $/year. The scattered distribution of shell diameter, baffle spacing, number of tube passes and number of tubes between the lower and upper bound represent their substantial role in optimizing the heat exchanger performance. The number of tubes and tube passes showed the maximum variation in efficiency, while significantly less impact was observed when the tube layout was altered.