Objective To investigate the influence of ultra early good limb position and inflated antispasmodic gloves combined with Brunnstrom period-specific rehabilitation training on the limb functions and living quality of stroke hemiplegic patients. Methods A total of 120 patients that had stroke hemiplegia for the first time, who were demonstrated through CT or MRI, and received from December 2013 to December 2014 in this hospital, were selected as study objects.For the patients whose disease time was less than 24 hours, they had limb dysfunction on one side, but there was no serious disturbance of consciousness.The patients were divided into control group and observation group (60 cases each) randomly. Usual care and conventional preventable rehabilitation exercise were applied to control group.Ultra early comprehensive rehabilitation nursing scheme was conducted to observation group within 24 hours of admission, including early good limb position placement and change.According to the rising degree of hand muscular tension, self-made inflated antispasmodic gloves were used to assist patients to keep good limb position.When the vital signs got stable, Brunnstrom 6-level rating method was used to have period-specific functional training. Before intervention and 4 weeks after intervention, the nurses of the same group applied Barthel index to have ADL evaluation and Brunnstrom period-specific movement function evaluation under single-blind condition.In addition, Stroke Impact Scale(SIS) was used to evaluate the living quality of patients and record the related complications during intervention. Results After 4 weeks of continuous rehabilitation intervention, the ADL scores and Brunnstrom classification of the observation group were obviously superior to control group.The difference had statistical significance(P<0.05). During the hospital stay, the muscle spasm, shoulder joint subluxation, foot drop and other complication occurrence rate of observation group was 10%, which was obviously lower than control group that was 63.3%. The dimensionality level of living quality of patients in observation group was obviously higher than control group.In addition, the overall level of living quality was high.The difference had statistical significance(P<0.05). Conclusion The combined application scheme of ultra early good limb position, inflated antispasmodic gloves and Brunnstrom period-specific rehabilitation training can give play to the potential repairability of injured brain tissue maximally, which can repair the injured motor neuron comprehensively, rebuild the function of nervous centralis and promote the recovery of the whole functions of patients.In addition, the effect on improving the living quality of stroke hemiplegic patients is significant. Key words: Good limb position; Antispasmodic; Brunnstrom training; Hemiplegia; Life quality