Trigeminal neuralgia (TN) is a painful condition that affects the lips, gums, cheeks, and chin. With a yearly incidence of 4 to 13 persons per 100,000. Allopathic therapies for TN include analgesics, anticonvulsants, and antidepressants. This is merely a short-term solution. After surgery, the pain will go away, but the facial numbness will remain. A 24-year-old female patient, complained of pain in the left half of the face with swelling and tingling sensation associated with tenderness in left cheek, in the past 3 months which aggravated since 15 days, She also complains of pain in the cervical region radiating to left upper limb since last 3 months associated with tingling sensation and numbness in left upper limb. Based on the signs and symptoms the condition was correlated to anantavata. Patient was managed in the IPD of KLE's Ayurveda Hospital, Belagavi, Karnataka, India, with internal medications and Panchakarma procedures. Outcomes were measured based on the relief in the symptoms presented at the baseline. There was no recurrence even after a 7-month follow-up period. Whole system Ayurveda treatment protocol was benecial in treating TN.