Studying the mechanical response of en-echelon joints under cyclic shear loading conditions can provide novel insights into the instability of jointed rock masses under seismic conditions. To investigate the effects of joint persistence, normal stress, cyclic distance, and shear velocity on the cyclic shear behavior of en-echelon joints, a series of cyclic shear tests in the laboratory was performed. Findings revealed that the failure morphography of en-echelon joints manifested through brecciated shear zones and abraded rupture surfaces, resulting in notable reductions in shear strength and significant compressibility. The degradation factor of shear strength ranged from 0.363 to 0.708 after ten cycles. The shear strength degradation factor showed an inverse relationship with joint persistence and normal stress while exhibiting a direct correlation with cyclic distance over ten cycles. En-echelon joints characterized by moderate joint persistence, high normal stress, small cyclic distance, and low shear velocity demonstrated increased cyclic friction strength. Moreover, normal stress and joint persistence exerted a more significant influence on shear strength compared to cyclic distance and shear velocity. For en-echelon joints, shear stiffness increased during small shear displacements with cycle number while decreased during large shear displacements; shear stiffness was inversely proportional to the cyclic distance and joint persistence, and directly proportional to the normal stress. Compressibility of en-echelon joints correlated directly with joint persistence, normal stress, cyclic distance, and shear velocity. Compared to normal stress and cyclic distance, joint persistence and shear velocity exhibited less influence on compressibility
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