Sexual Life Quality Questionnaire Research Articles

Development and Psychometric Evaluation of the Sexual Life Quality Evaluation Tool for Patients With Coronary Heart Disease.

Patients with coronary heart disease (CHD) will have a series of sexual problems, and their sexual life quality can be affected. However, a standardised evaluation tool for patients with CHD was lacking. Therefore, this study aimed to develop a sexual life quality questionnaire for patients with CHD and to evaluate its psychometric properties. Based on previous phenomenological studies, literature analysis and group discussion, questionnaire items were formed. After two rounds of expert consultation and pre-survey, the questionnaire items were modified. Items were screened by item analysis. Exploratory factor analysis and confirmatory factor analysis were used to explore and confirm the structure of the questionnaire. Content validity and criterion validity were evaluated using the expert consultation and correlation analysis, respectively. The questionnaire reliability was evaluated using internal consistency, split half reliability, and test-retest reliability. The sexual life quality questionnaire of patients with CHD was developed, which included two versions: male version and female version. The male version of the questionnaire contains 3 dimensions and 20 items, while the female version contains 3 dimensions and 17 items. After reliability and validity test, the two versions of the questionnaire have good reliability and validity. In this study, the sexual life quality questionnaire of patients with CHD was developed and its psychometric properties were confirmed, which can be used to evaluate the sexual life quality of patients with CHD. The development of a sexual life quality evaluation tool for patients with coronary heart disease to provide objective and quantitative tools for clinical staff to evaluate patients' sexual life status. Patients were invited to participate in a questionnaire survey for this study.

Sexual Dysfunction in Patients with Overactive Bladder Syndrome Treated with Botulinum Toxin

Introduction: Overactive bladder (OAB) is a syndrome of the lower urinary tract characterized by urinary urgency, frequency, and nocturia, with or without urgency urinary incontinence. OAB significantly impacts all aspects of life—social, psychological, physical, professional, domestic, and sexual—for both women and men. The aim of this study was to investigate sexual dysfunction in both women and men with OAB treated with intravesical onabotulinumtoxinA (Botox) injections using the Sexual Quality of Life questionnaire in two versions: female (SQoL-F) and male (SQoL-M). Methods: Forty sexually active patients (thirty women and ten men) with idiopathic OAB were recruited. Patients completed the SQoL-F or SQoL-M questionnaire before treatment, and again at 3 and 6 months after treatment with intravesical onabotulinumtoxinA injections. Results: All 40 patients completed the study (30 women and 10 men). There were no statistically significant differences in SQoL results before the procedure or at 3- and 6-months post-treatment. Conclusions: OAB treatment with onabotulinumtoxinA did not significantly affect the quality of sexual life in either women or men. Further research is needed using questionnaires specifically designed to assess the sexual life of patients with OAB, especially in men.

Effect of health education combined with biofeedback electrical stimulation on early pelvic floor function and psychology: A retrospective study.

To investigate the effects of health education combined with biofeedback electrical stimulation on maternal postpartum pelvic floor function and psychology. The clinical data of 80 patients with postpartum pelvic floor dysfunction (PFD) from May 2020 to May 2022 were selected as retrospective study subjects, and 40 cases were divided into the comparison group and the observation group according to the different intervention methods. Among them, the comparison group implemented biofeedback electrical stimulation and guidance, and the observation group implemented Greene health education and Kegel pelvic floor rehabilitation training intervention based on the comparison group. The differences in pelvic floor muscle strength, sexual quality of life, anxiety, and depression in the 2 groups with postpartum PFD were compared. Comparison of pelvic floor muscle strength: before the intervention (P > .05) and after the intervention, the anterior resting mean electromyography (EMG), slow muscle mean EMG, fast muscle maximum EMG, and mixed muscle mean EMG values of patients in the observation group were higher than those in the comparison group, and the posterior resting mean EMG values were lower than those in the comparison group (P < .05). There was no statistically significant difference in the Hospital Anxiety and Depression Scale (HADS) scores and anxiety and depression subscale scores between the 2 groups of patients before intervention (P > .05). After the intervention, the HADS scores and anxiety and depression subscale scores were lower than those before the intervention in both groups, and the differences were statistically significant in the intervention group than in the comparison group (P < .05). There was no statistically significant difference between The Chinese Female Sexual Life Quality Questionnaire scores of both groups before the intervention (P > .05). Sexual desire, vaginal lubrication, sexual arousal, sexual satisfaction, orgasm, and painful intercourse improved in both groups after the intervention, and the scores in the intervention group were higher than those in the comparison group (P < .05). Health education combined with biofeedback electrical stimulation can effectively improve the quality of patients' sexual life, improve the pelvic floor muscle strength of patients with postpartum PFD, enhance patients' confidence, reduce patients' anxiety and depression, and effectively improve patients' psychological status.

Depression scores and its relationship with sexual quality of life in women with type 1 and type 2 diabetes: A cross-sectional study.

Diabetes is an important public health problem with increasing prevalence worldwide. However, the prevalence of diabetes in women is increasing. Women with diabetes have many physical and psychological complications. It has been reported that complications experienced by women with diabetes negatively affect both their sexual and mental health. This study aimed to determine the sexual quality of life (SQoL) and depression scores in women with type 1 diabetes (T1D) and type 2 diabetes (T2D), the relationship between them, and to examine the factors predicting the SQoL. This study was analytical and cross-sectional. This study was conducted with 440 women with diabetes (206 women with type 1 and 234 women with type 2 diabetes) who came to the endocrine policlinic of a university hospital in Izmir, western Türkiye, between April and October 2023. Data were collected using the "Individual Description Form," "Sexual Quality of Life Questionnaire" and "Beck Depression Inventory." Correlation and multiple regression analyses were conducted to investigate the relationship between SQoL and depression scores. When women with T1D and T2D were compared, it was determined that women with T2D had worse SQoL and higher depression scores (P < .05). Both T1D and T2D women were found to have a strong negative correlation between SQoL and depression scores (r = -0.753; -0.837; P < .05). Age (B = -0.291), body mass index (BMI; B = -2.747), type 2 diabetes (B = -3.074), and depression scores (B = -1.898) were predictive factors of SQoL in women with diabetes (R2 = 0.670; P < .05). In our study, it was determined that depression scores were increased in women with diabetes mellitus with decreased SQoL. When T1D and T2D were compared, T2D had worse SQoL and higher depression scores. It also revealed that age, BMI, T2D, and depression scores affected SQoL. Healthcare professionals especially nurses should provide education and counseling to women with T1D and T2D about sexual life and mental health.

Erectile dysfunction in cardiovascular patients: A prospective study of the eNOS gene T‐786C, G894T, and INTRON variable number of the tandem repeat functional interaction

AbstractBackgroundCardiovascular disease induces erectile dysfunction modulated by endothelial nitric oxide synthase enzyme and an impaired ejection fraction that restricts penis vascular congestion. However, the mechanisms regulating endothelial dysfunction are not understood.ObjectivesExploring the functional impact of endothelial nitric oxide synthase genetic polymorphisms on erectile dysfunction and drug therapy optimization in high‐risk cardiovascular disease patients.Materials and methodsPatients with erectile dysfunction symptoms and candidates for andrology therapy were included (n = 112). Clinical data and endothelial nitric oxide synthase rs1799983 (G894T) and rs2070744 (T‐786C), genotyped by fluorescence polarization assays, were registered. The 27‐bp variable number of the tandem repeat polymorphism in intron 4 (intron4b/a) was analyzed by polymerase chain reaction‐restriction fragment length polymorphism. Association analyses were run with the R‐3.2.0 software.ResultsA significant association between endothelial nitric oxide synthase 786‐TT (p = 0.005) and the aa/ac of intron 4 variable number of the tandem repeat (p = 0.02) with higher erectile dysfunction susceptibility was observed in cardiovascular disease patients (60 ± 9 years, 66% severe erectile dysfunction, 56% ejection fraction). After 3‐months of phosphodiesterase type 5 inhibitors, erectile dysfunction (International Index of Erectile Function, 50 ± 16 scores, the International Index of Erectile Function‐Erectile Function 21 ± 10 scores, p &lt; 0.001) and sexual quality of life (modified Sexual Life Quality Questionnaire 55 ± 23 scores, p &lt; 0.001) had significantly improved. The cardiovascular ejection fraction was influenced positively with better sexual quality of life (0.1941), and also in the endothelial nitric oxide synthase G894‐T allele (p = 0.076) carriers, which could merit future analyses. Erectile dysfunction was present as the primary clinical manifestation in 62% of cases, with cardiovascular disease occurring concurrently. Only former smokers and obese subjects debuted prior to cardiovascular disease than to erectile dysfunction.ConclusionsOur study provides comprehensive insights into the functional interaction linking endothelial nitric oxide synthase gene polymorphisms, erectile function, and ejection fraction in high‐risk cardiovascular disease patients. Future therapeutic strategies could target endothelial nitric oxide synthase activity by including lifestyle changes and epigenetic modulations.

Selected Determinants Affecting the Quality of Sexual Life of Women Diagnosed with Multiple Sclerosis

Introduction. Multiple sclerosis is a chronic disease of the central nervous system, resulting from immune system dysfunction and characterized by demyelination and neurodegeneration. An essential aspect of therapy, besides improving overall quality of life, is also the quality of sexual life of patients with multiple sclerosis. Aim. The aim of this study was to assess the quality of sexual life of female patients with multiple sclerosis. Material and Methods. The study was conducted among 100 female patients diagnosed with multiple sclerosis in the Neurology Department. Research tools included a questionnaire regarding patients’ demographic and clinical data, as well as the Sexual Quality of Life Questionnaire — Female (SQoL-F). Results. The level of sexual quality of life among female patients with multiple sclerosis in the neurology department was associated with the following domains: psychosexual feelings, sexual satisfaction, relationship satisfaction, worthlessness, and sexual repression. 44% of women rated their relationship with their partner as poor. Sexual activity was rated as poor in 43% of cases, and 32% experienced a deterioration in their sexual life before and after the onset of multiple sclerosis. Factors such as demographic characteristics (place of residence, employment status, marital status) and clinical factors (obesity and diabetes) influenced the assessment of sexual quality of life. Conclusions. The mean score for quality of life in the SQoL-F questionnaire was 69.02 with a standard deviation of SD=25.86 and a median of Me=75. Both socio-demographic and clinical factors influenced the assessment of the level of sexual quality of life among patients with multiple sclerosis. (JNNN 2024;13(1):23–28)

The effect of exposure to emotional violence on sexual function, sexual quality of life and psychological well-being in women: Structural equation modeling

Emotional violence is all of the destructive behaviors that humiliate the individual and cause him/her to feel under pressure to disrupt mental health. These destructive behaviors can affect women's sexuality. In this study, it was aimed to determine the effect of exposure to emotional violence on sexual function, sexual life quality, and psychological well-being in women. The study was conducted in a descriptive and relational screening model. The sample of the study consisted of 213 women. Personal information forms, the female sexual function index, the sexual quality of life questionnaire, the exposure to emotional violence scale, and the psychological well-being scale were used in the study. Structural equation modeling was used to determine the direct and indirect predictive power of the independent variable on the dependent variable.The effect of exposure to emotional violence on psychological well-being (β = −0.323; p < 0.001), and the effect of quality of sexual life on psychological well-being were statistically significant (β =0.315; p < 0.001). Moreover, the effect of exposure to emotional violence on sexual life quality was determined to be statistically significant (β = −0.665; p < 0.001). The effect of quality of sexual life on female sexual function was statistically significant (β = −0.288; p = 0.002). Furthermore, while the effect of psychological well-being on the female sexual function index was not statistically significant (β = −0.101; p = 0.266), the effect of exposure to emotional violence scale on the female sexual function index was statistically significant (β = −0.087; p = 0.373). The mediating role of exposure to emotional violence in the relationship between sexual life quality and psychological well-being was high. Furthermore, the sexual life quality of 43.6 % of women was explained by exposure to emotional violence. On the other hand, 28.7 % of psychological well-being score was explained by the sexual life quality and exposure to emotional violence.

(235) Use of Bremelanotide (Vyleesi) in Men with Sexual Dysfunctions

Abstract Introduction Bremelanotide (Vyleesi) is an FDA approved medication for the safe and efficacious treatment of hypoactive sexual desire disorder in premenopausal women, however phase 3 trials revealed it improved arousal and orgasm as well. As a centrally acting drug it was expected to be effective to treat sexual dysfunctions in men and has been prescribed off label routinely in our practice. Objective The primary aim of this study was to evaluate the use of bremelanotide in men with various sexual dysfunctions, the reasons why the medication was prescribed, improvements in sexual function and overall satisfaction, and side effects experienced. Methods This one-group study design involved men from a single clinic with various sexual dysfunctions prescribed bremelanotide beginning May 1, 2021. After signing consent participants answered the Quality of Life (QOL) Dimension of Sexual Quality of Life Questionnaire, the Patient Global Impression of Improvement (PGI-I) and the General Assessment Questions (GAQ) online. After confirming they had used the medication at least twice, participants completed a structured interview over the telephone with a single interviewer. Descriptive statistics were used to characterize the study cohort. Adverse events were collected. Results To date a total of 21 men signed consent and 19 completed the online questionnaires. 80% of these men were more satisfied with their lovemaking and duration of lovemaking; 93% reported vaginal insertion was easier and 71% said it was easier to orgasm. With regard to feelings about initiating lovemaking, 86% were more at ease and 79% anticipated it would be more pleasurable and more carefree. 69% believed orgasm was more pleasurable and 73% said that lovemaking was more pleasurable while 79% reported that the partner’s overall experience was more pleasurable. Using the PGI-I, 53% of participants felt that sexual function after using bremelanotide was a little better, much better, or very much better. Additional questions online revealed similar results. Twelve men completed the one-on-one interview: 69% of participants were prescribed bremelanotide for erectile dysfunction. 64% had at least other one sexual health issue, including anxiety about sex (54%), low sexual desire (45%), not enjoying sex (36%), orgasm difficulties (18%), and ejaculation difficulties and sensation loss (9% each). A total of 91% experienced improvements in sexual function, all with improved erectile function. 100% of those with complaints of low sexual desire and/or complaints of anxiety around sex reported improvement; 64% had decreased anxiety around sex; 55% had more enjoyment with sex; and orgasm improved for 36% of participants. Men reported longer erection and ability for additional erection for 18-24 hours after bremelanotide injection, better connection between genitals and brain, improved sensitivity, and increased confidence. Side effects included flushing (36%), nausea (36%), headache (27%), bothersome spontaneous erections without sexual stimulation for about 24 hours after injection (27%), and incontinence, cramping and abdominal burning (9% each). All adverse events were transient. Conclusions While bremelanotide is approved for hypoactive sexual desire disorder in premenopausal women, it has been prescribed and used successfully for men with erectile dysfunction and other concomitant sexual health issues. Disclosure Yes, this is sponsored by industry/sponsor: Palatin Technologies. Clarification: Industry funding only - investigator initiated and executed study. Any of the authors act as a consultant, employee or shareholder of an industry for: Palatin Technologies.

Long-term tadalafil once daily in Chinese men with erectile dysfunction: a 2-year final analysis of a post-marketing, multicenter, randomized, open-label trial.

The long-term safety and effectiveness of once-daily tadalafil is crucial, but limited data are available in Chinese patients with erectile dysfunction (ED). In this post-marketing, multicenter, randomized, open-label trial with 2-year follow-up, 635 ED cases were randomized to receive daily oral tadalafil 2.5 mg or 5 mg for 3 months, of whom 580 continued once-daily tadalafil 5 mg for 21 months. Treatment-emergent adverse events in the 12-month and 24-month period were similar, with the most common being viral upper respiratory tract infection, upper respiratory tract infection, and headache. Significant improvement from baseline in the International Index of Erectile Function-Erectile Function (IIEF-EF) score was detected at month 12 (least squares mean [LSM] change: 7.9, 95% confidence interval [CI]: 7.5-8.4, P < 0.001) and was maintained to month 24 (LSM change: 8.6, 95% CI: 8.1-9.0, P < 0.001). The proportions of patients regaining normal erectile function (IIEF-EF score ≥26) were 43.7% and 48.0% at months 12 and 24, respectively. Global Assessment Questionnaire results showed improved erection function in 97.5% of patients and improved ability to engage in sexual activity in 95.9% of patients at month 12; these values were 96.1% and 95.0% at month 24, respectively. The quality of sexual life score based on the Sexual Life Quality Questionnaire (SLQQ) was increased by 52.2% at month 12 and by 55.3% at month 24 (both P < 0.001). The treatment satisfaction score determined by SLQQ (mean ± standard deviation) was 62.4 ± 21.0 at month 12 versus 65.9 ± 20.2 at month 24. Two-year daily application of tadalafil 5 mg in Chinese men with ED showed a favorable safety profile and durable improvement in sexual performance and satisfaction.

Comparison of the Effectiveness of Emotion-Focused Therapy and Intensive Short-Term Psychodynamic Therapy on Sexual Dysfunction and Quality of Sexual Life in Women

Objective: The present study aimed to compare the effectiveness of emotion-focused therapy and short-term psychodynamic therapy on sexual dysfunction and the quality of sexual life in women attending counseling and psychotherapy centers in Isfahan. Methods: The research design was a quasi-experimental pre-test, post-test, and follow-up. The population included all women in Isfahan province suffering from sexual dysfunction in 2023. Sixty individuals were selected through purposive sampling and randomly assigned into three groups: twenty in the first experimental group, twenty in the second experimental group, and twenty in the control group. The first experimental group underwent emotion-focused psychological intervention based on the therapeutic protocol by Gilbert (2014) in fifteen 60-minute sessions, and the second experimental group received short-term psychodynamic psychological intervention based on the therapeutic protocol (Davanloo, 2013) in twelve 60-minute sessions held weekly, followed by a one-month follow-up. The control group was placed on a two-month waiting list for the most effective intervention. Data collection for analysis was conducted using the Rosen et al. (2000) Women's Sexual Dysfunction Questionnaire and the Simonds et al. (2005) Women's Sexual Life Quality Questionnaire. Data analysis was performed using mixed ANOVA with SPSS version 25. Findings: The findings indicated that both treatments were effective in reducing sexual dysfunction in women (F = 73.08, p &lt; .001) and improving the quality of sexual life (F = 18.02, p &lt; .001). However, there was a significant difference between the effectiveness of the two therapeutic methods in reducing sexual dysfunction and increasing the quality of sexual life in women (p &lt; .001). Conclusion: It can be concluded that both emotion-focused and short-term psychodynamic therapies are effective in reducing sexual dysfunction and improving the quality of sexual life in women. Both treatments can be used to reduce psychological issues in women attending counseling centers.

Quality of sexual life in Mexican men after spinal cord injury.

To evaluate the quality of sexual life in men with spinal cord injury. Cross-sectional analytical study. Males with a history of spinal cord injury who attended an outpatient rehabilitation service. An analytical study examined adult male patients with complete spinal cord injuryin rehabilitation. A modified Sexual Life Quality Questionnaire (SLQQ) examined quality of sexual life, with scores below 50 suggesting significant sexual dysfunction and dissatisfaction. The assessment evaluated age, occupation, marital status, comorbidities, and treatment methods. A total of 80 patients were included; 33 (41%) had a thoracic spinal cord injury, and 47 (59%) had a lumbar spinal cord injury. Thirty-seven patients (46%) were dissatisfied with the quality of their sexual life; 29 patients (88%) with thoracic spinal cord injury and 8 patients (17%) with lumbar spinal cord injury were dissatisfied with the quality of their sexual life (p = 0.001). Patients with higher education level experienced less sexual dissatisfaction (p = 0.03). Human sexuality involves numerous interconnected elements that impact on general health. Sexual pleasure, self-esteem, and personal relationships are crucial for patients with spinal cord injury to identify rehabilitation needs. These resultsindicate the importance of supporting sexual well-being in recovery. Further studies of sexual enjoyment and quality of life for patients with spinal cord injury are needed, using larger and more diverse populations.

Relationship between sexual quality of life and life satisfaction in women with urinary incontinence: A cross-sectional survey.

This study aims to investigate the relationship between the sexual quality of life and life satisfaction in women with urinary incontinence. This research is Correlational-descriptive research. Sample of the study consisted of 210 women with urinary incontinence. The data of the study were collected using "The Patient Information Form," "The Sexual Quality of Life Questionnaire" and "The Satisfaction with Life Scale." In analyzing; Mann-Whitney U tests, Kruskal Wallis variance analysis were used. It has been found that educational status, income status, menopause status, and frequency of urinary incontinence affect the sexual quality of life. A statistically significant positive moderate linear relationship was found between the mean SWLS scores and the mean SQOL scores (p < 0.05). In this study, it was found that the sexual quality of life increased as The Life Satisfaction Of Women With Urinary Incontinence Increased.

Quality of sexual life and associated factors: a cross-sectional survey of Chinese breast cancer patients.

This study aimed to explore Chinese breast cancer patients' quality of sexual life (QSL) and factors associated with QSL. The questionnaires in this cross-sectional study include the general information questionnaire, cognition and assessment of sexual health questionnaire, Self-acceptance Questionnaire (SAQ), Medical Coping Modes Questionnaire (MCMQ), and Quality of Sexual Life Questionnaire (QSLQ); 201 breast cancer patients were required to complete the questionnaires assessing characteristic information, cognition and assessment of sexual health, QSL, self-acceptance, and coping style. Finally, hierarchical regression was used to analyze the factors associated with QSL in Chinese breast cancer patients. The mean age (at the time of the survey) of the breast cancer patients was 48.31±9.15. The mean score of the QSLQ (range 28-140) was 75.14±16.57. Hierarchical regression analysis showed that the associated factors of breast cancer patients' QSL included age (at the time of the survey), education level, type of surgery, cognition and assessment of sexual health, self-acceptance, and avoidance and acceptance-resignation coping styles, that independent variables explained 60.4% of the variance. The QSL among Chinese breast cancer patients needs to be improved. Our findings indicated that breast cancer patients with older age, lower education level, or modified radical mastectomy have poor QSL. Breast cancer patients learn correct information about sexual health, enhance self-acceptance, and reduce acceptance-resignation, and avoidance coping could be intervention strategies to improve their QSL.

Female Genital Mutilation, Sexual Quality of Life and Marital Relationship: A Case-Control Study From Iran.

Studies on the sexual consequences of female genital mutilation is mostly related to sexual function, while sexual quality of life is a more objective criterion for studying the effects of genital mutilation on the women's sexual life. The purpose of this study was to compare the sexual quality of life and marital relationship in the mutilated women with other women living in the Kurd region of Mahabad (Iran). In a case-control study, 600 married women (300 mutilated and 300 non-mutilated women) who referred to the health centers completed the sexual quality of life questionnaire (SQOL-F) as well as demographic questionnaires. Data analyzed using chi-square, independent t-test, and linear regression model with stepwise method at 95% confidence level. The mean total score of sexual quality of life in the mutilated group (40.28±16.76) was significantly lower than the control group (45.29±19.16). The chance of having a higher score of sexual quality of life in the mutilated group was 0.13 times lower than the control group. This value was 0.16 times for self-worthlessness area, 0.10 for sexual repression, 0.12 for psycho-sexual feeling, and 0.32 for sexual and marital satisfaction areas (p <0.05). In the mutilated group, the total score of sexual quality of life was significantly correlated with age, income, spouse's violence, spouse's infidelity, intercourse frequency, and residence status (P <0.05). Female genital mutilation can decrease the sexual quality of life and increase the chance of negative consequences such as spouse violence, infidelity, and intercourse reduction.

Investigating the Sexual Quality of Life of Deaf and Hard-ofHearing Married Women: A Cross-sectional Study

Background and Objective: Hearing impairment is a vital health issue and harms people’s lives. This study aimed to examine the sexual quality of life (QoL) of deaf and hard-of-hearing married women living in Mazandaran Province, Sari City, Iran. Materials &amp; Method: The present cross-sectional descriptive study was conducted on 132 deaf and hard-of-hearing women referred to the Deaf Center in Mazandaran Province, Sari City, Iran, in 2021. Sampling was done using the convenience method among all married women with hearing impairment referred to that center from July to November 2021. Information was collected with demographic form and Simonds’ sexual quality of life questionnaire. The obtained data were analyzed with t test and analysis of variance. The significance level was considered 0.05 in all tests. Results: The Mean age of the participants in this study was 36.45±7.17 years, and their Mean score of the quality of sexual life was 16.67±83.86. In this study, a significant relationship was observed between the sexual QoL of the participants and their participation in the reproductive health virtual groups. No significant relationship was observed with other variables, such as education, wife’s education, husband’s hearing status, participant’s hearing status, use of hearing aids, number of pregnancies, type of delivery, and history of abortion. Conclusion: According to the results of this study, appropriate methods should be used, including peer-based training and sign language interpreters in sexual health issues.

Mediation effects of individuals’ sexual quality of life on the relationship between sexual quality of life of partners and its predictors: a path analysis

Sexual function and the sexual quality of life of an individual could be influenced by several factors. Sexual dysfunction could affect the sexual quality of life of the individual and, possibly, have an impact on their partners. Treatments that improve sexual function among individuals tend to improve the sexual quality of life of their partners. This study explored the mechanism by which an individual’s sexual quality of life mediates the relationship between factors, such as age, sexual dysfunction, perception of IELT, and the partner’s sexual quality of life. Path analysis was used to determine if this effect was via direct or indirect mechanisms. Outpatients attending the Maamobi and Tema General Hospitals, as well as their partners, were recruited for this study. A total of 130 males and their partners, as well as 116 females and their partners, were recruited. The GRISS was used to evaluate the sexual function of participants. The sexual quality of life questionnaire was used to evaluate participants and their partners. Ageing in both sexes had a direct effect on the sexual quality of life of their partners. Ageing also indirectly compromises the sexual quality of life of male partners. Impotence indirectly affects the sexual quality of life of female partners. Vaginismus indirectly affected the sexual quality of life of their male partners. Among the male participants, avoidance of sexual activity had both direct and indirect effects on the sexual quality of life of their female partners. Avoidance of sexual activity by female participants only had an indirect effect on the sexual quality of life of the male partners. Ageing in both sexes, directly compromises the sexual quality of life of their partners.

Development of a Sexual Quality of Life Questionnaire for Men-Who-Have-Sex-With-Men With Prostate Cancer.

BackgroundProstate cancer (PCa) is often diagnosed early with prolonged survival, which makes sexual quality of life (QoL) an increasingly important treatment consideration, but existing QoL questionnaires have limited applicability for men who-have-sex-with-men (MSM) beyond penile erections and penetrative sex.AimWe aimed to create a validated survey instrument for assessing a variety of sexual activities beyond penile insertive sex for MSM after PCa treatment.MethodsBased on our previously published survey findings, we have generated a prototype questionnaire with 13 different domains, reviewed by both healthy MSM and pilot-tested by MSM treated for PCa.OutcomesWe report here on progress in developing the questionnaire and demonstrate the complexity of MSM sexual side effects resulting from PCa treatment(s).ResultsStatistical analysis of 204 responses from MSM treated for PCa showed that each domain performed well individually (Cronbach's alpha coefficients ranged from 0.80 to 0.95; item-total correlations ranged from 0.16 to 0.89), with many significant intercorrelations between the domains (ranged from -0.048 to 0.93).Clinical ImplicationsThe questionnaire can contribute to clinical diagnosis and treatment decisions that best fit the preferred sexual practices of individual MSM.Strengths & LimitationsThe current questionnaire considers a much broader repertoire of MSM's sexual practices and preferences than other currently available questionnaires. The high intercorrelations between the many parameters demonstrate that problems in one domain can affect other domains. This preliminary analysis warrants further exploration with a larger sample size.ConclusionsOnce validated our questionnaire should help develop tailored psychosocial supports for MSM experiencing sexual dysfunction after PCa treatment and help newly diagnosed MSM with PCa make treatment decisions informed by their preferred sexual practices.Wibowo E, Dowsett GW, Nelson CJ, et al. Development of a Sexual Quality of Life Questionnaire for Men-Who-Have-Sex-With-Men With Prostate Cancer. Sex Med 2022;10:100480.

Assessment of depression and sexual quality of life in postmenopausal women

To determine the prevalence of depression, review some variables that are believed to be associated and assess the relationships between depression and sexual quality of life in postmenopausal women. This is a cross-sectional study conducted on postmenopausal women in Ankara, Turkey from February to June 2020. The study group consisted of 242 postmenopausal women. The Beck Depression Inventory and Sexual Quality of Life Questionnaire were used to assess the level of depression and sex life, respectively. Online questionnaire forms (Google Form) prepared by using the literature in line with the study objective were completed by the women online. Independent t-test, analysis of variance, Tukey's test, and Pearson's correlation analysis were used for statistical analyses. Statistical significance was accepted as p ≤ 0.05. The of women was found to be 52.64 (±6.245) years and the average menopause age was found to be 47.81 (±4.039) years in this study. The mean score obtained by the women from the Beck Depression Inventory was 13.04 (±7.82). It was determined that the women showed "mild depressive symptoms" mostly. As for the women's sexual quality of life, the mean score obtained from the Sexual Quality of Life Questionnaire was 61.32 (±14.70). A statistically significant and moderate negative correlation was detected between the mean scores obtained by the women from the Beck Depression Inventory and the Sexual Quality of Life Questionnaire (r = -0.305; p < 0.01). It was determined in the study that sexual quality of life is affected by menopause negatively and the women had mild depressive symptoms. Depression among postmenopausal women is an important women's health problem that should be addressed. A negative correlation was found between depression and sexual quality of life. Early diagnosis and treatment of menopause as well as activities for raising awareness among postmenopausal women will be effective in improving quality of life.

COVID-19 Salgınının Kadınlarda Eş Uyumu ve Cinsel Yaşam Kalitesine Etkisi

ÖZET&#x0D; AMAÇ: Bu çalışmanın amacı, COVID-19 salgınının kadınlarda eş uyumu ve cinsel yaşam kalitesine etkisini incelemektir. &#x0D; MATERYAL METOT: İnternet tabanlı kesitsel tipte olan bu çalışma, web tabanlı bir çevrimiçi anket kullanılarak yürütüldü. Araştırmada anket formları 15 Haziran-15 Ağustos 2020 tarihleri arasında sosyal medya aracılığıyla 386 kadına uygulandı. Anket formunda kadınların sosyodemografik özellikleri, COVID-19 pandemisinde cinselliğe ilişkin bilgileri içeren sorular, Yenilenmiş Çift Uyum Ölçeği (YÇUÖ) ve Cinsel Yaşam Kalitesi Ölçeği-Kadın (CYKÖ-K) yer aldı. &#x0D; BULGULAR: Kadınların %73,8’i COVID-19 pandemisinde eş ilişkilerinin olumsuz etkilenmediğini, %71,8’i cinsel yaşamının olumsuz etkilenmediğini belirtti. Eş ilişkisi ve cinsel yaşamının olumsuz etkilendiğini ifade eden kadınların YÇUÖ toplam, Uzlaşım ve Görüş Birliği alt boyutları puan ortalamalarının, eş ilişkisi ve cinsel yaşamının olumsuz etkilenmediğini ifade eden kadınlardan daha düşük olduğu ve gruplar arasındaki farkın istatistiksel olarak anlamlı olduğu belirlendi (p

A Botanical Product Containing Cistanche and Ginkgo Extracts Potentially Improves Chronic Fatigue Syndrome Symptoms in Adults: A Randomized, Double-Blind, and Placebo-Controlled Study.

Dietary therapy may be beneficial in alleviating symptoms of chronic fatigue syndrome (CFS), a disorder that is characterized by extreme fatigue and other symptoms, but the cause of which remains unclear. The aim of this study was to evaluate the protective effect of a botanical product containing cistanche (Cistanche tubulosa [Schenk] Wight) and ginkgo (Ginkgo biloba L.) extracts on adults with CFS in a randomized, double-blind, placebo-controlled clinical trial. A total of 190 subjects (35–60 years old, non-obese) with CFS were randomized to receive one tablet of a low dose (120-mg ginkgo and 300-mg cistanche), a high dose (180-mg ginkgo and 450-mg cistanche) or a placebo once daily for 60 days. Blood samples and responses on the Chalder fatigue scale (CFQ 11), the World Health Organization's quality of life questionnaire (WHOQOL), and the sexual life quality questionnaire (SLQQ) were collected at baseline and post-intervention. CFS symptoms of impaired memory or concentration, physical fatigue, unrefreshing sleep, and post-exertional malaise were significantly improved (p < 0.001) in both of the treatment groups. The botanical intervention significantly decreased physical and mental fatigue scores of CFQ 11 and improved WHOQOL and SLQQ scores of the subjects (p < 0.01). Levels of blood ammonia and lactic acid in the treatment groups were significantly lower than those of the placebo group (low-dose: p < 0.05; high-dose: p < 0.01). In addition, the change in lactic acid concentration was negatively associated with the severity of CFS symptoms (p = 0.0108) and was correlated with the change in total physical fatigue score of the CFQ (p = 0.0302). Considering the trivial effect size, the results may lack clinical significance. In conclusion, this botanical product showed promising effects in ameliorating the symptoms of CFS. Clinical trials with improved assessment tools, an expanded sample size, and an extended follow-up period are warranted to further validate the findings.Clinical Trial Registration: https://clinicaltrials.gov/, identifier: NCT02807649.