Female Sex Ratio Research Articles

Age and growth of American Eel in lower St. Johns River in northeast Florida

AbstractObjectiveLittle is known about American Eel Anguilla rostrata populations across much of the species' large geographic range. This study aimed to collect important information on the life history and population biology of American Eel in a northeast Florida river.MethodsDuring two 12‐week periods, from August to November 2021 and September to December 2022, American Eel were collected from a ~90‐km stretch of the lower St. Johns River via boat electrofishing. Data on length, weight, age, Anguillicoloides crassus parasite infection, and swim bladder condition were recorded for American Eel collected in both years, and additional data on sex, sexual maturity, and fin and eye morphology were recorded for American Eel collected in 2022.ResultOverall, biologists spent more than 63.5 h of effort over 42 sampling days to collect 297 American Eel, ranging in size from 150 to 705 mm total length (TL) with a continental age ranging from 0 to 8 years. American Eel catches were low and varied by section of river and over time; however, no differences in the length–weight relationship or size structure were observed between river sections. Adult parasites were observed in swim bladders of 36% of American Eel, and 57% of eel exhibited some level of swim bladder damage. Although length–weight relationships were similar regardless of swim bladder condition, relative swim bladder length was lower for fish with severe damage. Histological examination of gonads from 160 American Eel in 2022 revealed that the male : female sex ratio was 0.9:1 and nearly all eel were sexually immature. The majority of fish were 2–4 years of age; average growth was modeled with a von Bertalanffy curve for American Eel aged 1–8: TL = 740 × [1 – e−0.12(age + 1.98)].ConclusionGiven the paucity of information about American Eel in this region, the data provided in this study will be critical to informing future decisions on the management of the American Eel stock.

Feeding Aspects and Reproductive Biology of Smalltooth Emperor, Lethrinus microdon (Valenciennes, 1830) in the Gulf of Mannar along the Indian Southeast Coast

Background: The Gulf of Mannar, situated on the southeast coast of India, is a unique distinctive productive marine ecosystem and is rich in biodiversity. Its significance stems from the presence of a string of 21 islands spanning 140 km between Rameswaram and Tuticorin, each adorned with a wealth of coral reefs and hosting a variety of ornamental and marine fish species despite their small and uninhabited nature. It is also first Marine Biosphere Reserve in South and South-East Asia, covers approximately an area of 19,000 sq. km. Methods: Fish samples were collected monthly from three major fishing harbours situated in the Gulf of Mannar along the southeast Coast: Thoothukudi Fishing Harbour, Pamban Fishing Harbour and Chinnamuttom Fishing Harbour from December 2022 to November 2023. These species are caught using trawl net, gill net and hook and line and collected specimens were identified using FAO sheets and standard literature. Result: In this study, a total of 405 specimens were collected. The length weight relationship was estimated for male: W = 0.0522.57, r2 = 0.94, female; W = 0.0572.51, r2 = 0.94; and pooled; W = 0.0632.54, r2 = 0.90, respectively. Fulton condition factor (KF) value for male: 1.22, female: 1.33; and pooled: 1.19, respectively. Gonadosomatic index (GSI) of L. microdon was ranged between 1.21-2.21 for male and 1.85-2.31 for female and Gastrosomatic index (GaSI) varied from 1.45-2.37 for male whereas 1.89-4.43 was found for female. Hepatosomatic index (HSI) of L. microdon was ranged between 0.45-2.54 for male while for female was ranged between 1.11-3.21. The male and female (M:F) sex ratio was estimated 1:0.67. The peak spawning season was observed in June to August. The results provide the baseline biology information required to evaluate the fisheries and sustainable management of these underexploited fishes in the Gulf of Mannar ecosystem.

Carrier frequency and molecular basis of hemoglobinopathies among blood donors in eastern Morocco: Implications for blood donation and genetic diagnosis

BackgroundHemoglobinopathies represent the most commonly inherited autosomal recessive blood disorders in the world. The aim of this study was to determine the carrier frequency and molecular basis of hemoglobinopathies among blood donors in eastern Morocco. This is the first study of its kind for this country. MethodsHealthy blood donors of the BRO Biobank were included in this study. Blood samples were analyzed using an automatic blood cell analyzer for complete blood counts. Hemoglobin fractions were analyzed by capillary electrophoresis and serum ferritin was measured on a chemical and immunological analyzer. Suspected hemoglobinopathy carriers were further characterized by Sanger sequencing, Gap PCR and PCR-RFLP. ResultsThe study involved 2013 blood donors, of whom 1063 were male and 950 were female (sex ratio male-to-female of 1.1). The median age of these donors was 35 years. The overall carrier frequency of hemoglobinopathies was 1.84 %, with β-thalassemia carriers being the most prevalent (0.65 %) followed by HbAC (0.55 %), α-thalassemia carriers (0.30 %), HbAS (0.1 %), HbAG-Philadelphia (0.1 %), HbAD-Ouled Rabah (0.05 %) and HbAO-Arab (0.05 %). Additionally, novel β-thalassemia variants (C6(−G) and −83(A > G)) and a structural variant (Hb D-Ouled Rabah) were discovered for the first time in Morocco. ConclusionsThis study provided the first report on carrier frequency and molecular basis of hemoglobinopathies among healthy donors in Morocco. These findings are valuable for the implementation of carrier screening and genetic diagnosis for hemoglobinopathies. Furthermore, these results justify the need to introduce pre-donation screening for hemoglobinopathy carriers in Morocco, particularly in areas with a high prevalence of carriers to enhance the overall quality of the national blood supply.

Population estimate and habitat association of Grant’s gazelle (Nanger granti Brooke, 1872) in the Ene Forest of Dale Sadi district, western Ethiopia

Grant’s gazelles (Nanger granti) are classified as of least concern by the IUCN, although their number is declining due to several factors. A few research studies have been conducted on Grant’s gazelle in Ethiopia. Thus, the present study was carried out to determine the population size and habitat association of Grant gazelle in the Ene Forest of western Ethiopia, comprising the dry and wet seasons. The study area was stratified into four habitats: woodland, mixed woodland, riverine forest, and grassland habitats. The data were collected using the direct observation technique. The data were analyzed using descriptive statistics and Pearson’s chi-square (χ2) test. The average estimated Grant gazelle population was 136 ± 23 individuals, with a density of 9/km2. The adult male-to-adult female sex ratio was 1:1.40 and 1:1.26 during the wet and dry seasons, respectively. The largest herd size (N = 6) was observed during the wet season, and the smallest (N = 4) was observed during the dry season. The highest numbers of Grant gazelles were observed in the grassland habitat during the wet season and in the woodland during the dry season. More Gazelles (N = 65) were observed in the woodland habitat compared to the other habitat types. The continued existence of the Grant’s gazelle population in the area and the suitability of the environment depend significantly on ongoing assessments of habitat change and management intervention.

Incidence and risk factors of radial artery spasm during distal radial angiography

Objective: Radial artery spasm (RAS) is a common complication of radial coronary angiography. Our aim was to assess how different risk factors influence the occurrence of RAS during distal radial coronary angiography. Patients and Methods: A total of 183 consecutive patients undergoing distal radial angiography at 2 centers were included in our study. RAS was defined clinically. The relationship between the demographic and clinical characteristics of the patients and the development of RAS was evaluated. Results: Radial artery spasm developed in 23 (12.5%) of the patients. While the female sex ratio was higher in those who developed RAS, the mean age was lower (p

Determination of the frequency and distribution of APC, PIK3CA, and SMAD4 gene mutations in Ugandan patients with colorectal cancer

Uganda is a developing low-income country with a low incidence of colorectal cancer, which is steadily increasing. Ugandan colorectal cancer (CRC) patients are young and present with advanced-stage disease. In our population, there is a scarcity of genetic oncological studies, therefore, we investigated the mutational status of CRC tissues, focusing in particular on the adenomatous polyposis coli (APC), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), and SMAD4 genes. Our objective was to determine whether there were any differences between other populations and Ugandan patients. We performed next-generation sequencing on the extracted DNA from formalin-fixed paraffin-embedded adenocarcinoma samples from 127 patients (mean (SD) age: 54.9 (16.0) years; male:female sex ratio: 1.2:1). Most tumours were located in the rectum 56 (44.1%), 14 (11%) tumours were high grade, and 96 (75.6%) were moderate grade CRC. Stage III + IV CRC tumours were found in 109 (85.8%) patients. We identified 48 variants of APC, including 9 novel APC mutations that were all pathogenic or deleterious. For PIK3CA, we found 19 variants, of which 9 were deleterious or pathogenic. Four PIK3CA novel pathogenic or deleterious variants were included (c.1397C > G, c.2399_2400insA, c.2621G > C, c.2632C > G). Three SMAD4 variants were reported, including two pathogenic or deleterious variants (c.1268G > T, c.556dupC) and one tolerant (c.563A > C) variant. One novel SMAD4 deleterious mutation (c.1268G > T) was reported. In conclusion, we provide clinicopathological information and new genetic variation data pertinent to CRC in Uganda.

INFLUENCE OF JAPANESE QUAIL EGG SHAPE INDICES ON CHICK SEX RATIO

Japanese quails are still in the domestication process and it has been observed that while in captivity,they do not sit on their eggs to hatch them. Separation of the males and females such that the recommended ratio is kept in a covey, is necessary for-profit maximization. Presently, sexing in quails is only possible at post hatch even, with the most popular Japanese vent examination technique. Besides, these techniques may be inaccurate, require expertise, facilities and may not be affordable by many farmers hence, the need to use egg shape to predetermine Japanese quail chicks. Egg length, width and indices were used to categories the egg shapes into Round (44), Oval (139), Spherical (9) and Elliptical (60). The 252 Japanese quail eggs were set in an artificial incubator. At hatch, the number of eggs hatched was recorded per egg shape. At 3 weeks of post hatch, the chicks’ sex was identified using the breast feather colour and the number of male and female chicks was recorded. Out of the 252 Japanese quail eggs incubated, 191 representing 75.8% hatched, whereas in 44 Round eggs incubated 36 hatched, 139 Oval eggs (102 hatched), 9 Spherical eggs (7 hatched) and in 60 Elliptical eggs, 46 hatched. While hatchability varied between 73.3 and 81.9% in all the egg shapes examined, the male to female chick sex ratio was 13:23, 20:31, 7:0 and 11:12 in Round, Oval, Spherical and Elliptical eggs, respectively. Since both sexes were recorded in all the egg shapes (except, Spherical eggs), Japanese quail egg shape may not influence chick sex. Thus, use of egg indices may not be a veritable technique to predetermine Japanese quail chick sex.

Large and interactive pipefish females display ornaments for longer with many males around

Why do animals display sexual ornaments – to attract mates, to compete for access to them, or both? In the broad-nosed pipefish (Syngnathus typhle), ornamented females commonly compete for access to males, whereas choosy males provide uniparental care. During courtship, females show a dynamic ornament, consisting of a row of dark B-shaped signs along the sides of their trunk. Here, we focus on the social context of female ornamentation and mating success (egg transfer) under experimentally female and male biased adult sex ratios. We found that the duration of female B-sign displays was not explained by adult sex ratios alone, but rather by sex ratios in combination with female body length and the number of female interactions. In detail, duration of B-sign display increased more steeply with the number of female-female interactions under the male biased adult sex ratio: that is, when more mating opportunities were available. Similarly, display duration increased with female body length, but only under the male biased adult sex ratio. In addition, successful egg transfer occurred more often in the male biased treatment and correlated significantly with female display duration in the same treatment. Taken together, these results suggest that in the context of the broad-nosed pipefish, the ornamental B-signs in females primarily serve as a sexually selected attractive signal. Our results highlight the importance of an interactive mating environment, male availability, and female size.

The Correlation Between the Willingness to Marry and the Household Savings Rate in China

In recent years, the decrease in household savings rate and willingness to marry is an important problem facing society in China. The traditional competitive savings theory holds that the imbalance of the male and female sex ratio is an important factor affecting the household savings rate. However, in the context of the saving rate declining year by year after 2010, it is found that the traditional competitive savings theory can not fully explain the reasons for its decline. At the same time, according to the data statistics, it is found that the trend of marriage intention in China during 2000-2021 is similar to that of the savings rate, which increases first and then decreases. Therefore, this paper established a multiple linear regression model and ridge regression model for regression analysis, and observed the size of the regression coefficient and the positive and negative effects of willingness to marry on household savings rate in China. The regression results show that for every 1% change in willingness to marry, the savings rate will change 13.526% in the same direction on average. This indicates that the decline in willingness to marry plays a positive role in explaining the decline of household savings rate.

The Correlation between Female Literacy and Juvenile Sex Ratio in Nashik District: A Geographical Perspective

The Correlation between Female Literacy and Juvenile Sex Ratio in Nashik District: A Geographical Perspective

A Study on Effects of Species with the Adaptive Sex-Ratio on Bio-Community Based on Mechanism Analysis and ODE

The species of the adaptive male–female sex ratio has different effects on the bio-community. This paper is aimed at figuring out these effects through mechanism analysis and Ordinary Differential Equation (ODE). Hence, the ODE environmental model is created by combining the Lotka–Volterra model, the interspecific model, and other external factors. The stability is used to characterize these effects. According to this model, effects on bio-community stability under different male–female sex ratios are roughly observed. By innovatively considering different living environments during the species’ lifecycle, the ODE environmental model is optimized, and the effects of different male–female sex ratios on the bio-community are further analyzed by phase-track maps and relative standard deviation. It is found that there are different findings and features in resource-rich and resource-scarce living environments during the lifecycle. Meanwhile, bio-communities in these two types of environments are in a stable state based on different male–female sex ratios. Based on these findings, directive opinions can be used to manage and help relevant bio-communities.

Studi Bioekologi Betta fusca di Labuhanbatu Raya Sebagai Bahan Ajar untuk Mata Kuliah Ekologi Hewan

This research aims to determine the bioecological aspects of Betta fusca as teaching material for the Ecology Course. The research method used is an exploratory method. The research results showed that the length-weight relationship of Betta fusca fish showed negative allometric results, which means that the increase in length of the fish was not proportional to the increase in weight. The male to female sex ratio was found to be 1:2, indicating the predominance of females over males in the observed population. The physical and chemical parameters of the water observed showed variations, but everything was still in optimum conditions to support the life of Betta fusca. The conclusion of this research is that the bioecological conditions of Betta fusca in Labuhanbatu Raya Regency still support the sustainability of the population of this species. Keywords: Betta fusca, Bioecology, Animal Ecology

Rickettsia symbionts spread via mixed mode transmission, increasing female fecundity and sex ratio shift by host hormone modulating

Heritable symbionts are common among animals in nature, but the molecular mechanisms underpinning symbiont invasions of host populations have been elusive. In this study, we demonstrate the spread of Rickettsia in an invasive agricultural pest, the whitefly Bemisia tabaci Mediterranean (MED), across northeastern China from 2018 to 2023. Here, we show that the beneficial symbiont Rickettsia spreads by manipulating host hormone signals. Our analyses suggest that Rickettsia have been horizontally acquired by B. tabaci MED from another invasive whitefly B. tabaci Middle East-Asia Minor 1 during periods of coexistence. Rickettsia is transmitted maternally and horizontally from female B. tabaci MED individuals. Rickettsia infection enhances fecundity and results in female bias among whiteflies. Our findings reveal that Rickettsia infection stimulates juvenile hormone (JH) synthesis, in turn enhancing fecundity, copulation events, and the female ratio of the offspring. Consequently, Rickettsia infection results in increased whitefly fecundity and female bias by modulating the JH pathway. More female progeny facilitates the transmission of Rickettsia. This study illustrates that the spread of Rickettsia among invasive whiteflies in northeastern China is propelled by host hormone regulation. Such symbiont invasions lead to rapid physiological and molecular evolution in the host, influencing the biology and ecology of an invasive species.

EVALUATION OF HEPATIC MASS LESIONS BY DIFFUSION WEIGHTED MAGNETIC RESONANCE IMAGING

Objectives: The purpose of this study was to compare apparent diffusion coefficient (ADC) values for benign and malignant neoplastic hepatic lesions and also for suspected infective hepatic masses in which histopathology may always not be indicated. Methods: This is a cross-sectional study conducted in the department of radio diagnosis and imaging, army hospital research and referral, Delhi Cantt. All the patients coming for magnetic resonance imaging (MRI) scans for focal liver lesions detected on other imaging modalities were included. The imaging was done at the 1.5 Tesla MAGNETOM AVANTO A Tim system (Siemens Ltd.). Various parameters of the morphology of lesions in conventional MRI and parameters in diffusion-weighted MRI were evaluated. Results: A total of 75 patients were included in the study. The mean age of the subjects was 52.57±15.28 years, with a male: female sex ratio of 0.5:1. Among the 75 subjects, 20 subjects with hepatic cysts had no restrictions, and 12 patients with hemangioma were hyperintense on both diffusion-weighted imaging (DWI) and ADC. The mean differences between benign and malignant lesion ADC values. The difference was statistically significant (p<0.001). In the present study, we get a cut-off for the ADC value of 1.581×10-3 mm2/s, which proved to be an optimal parameter for differentiation between benign and malignant lesions. Conclusion: DWI proved to be a very useful supplementary imaging technique in conjunction with conventional imaging sequences in the analysis of focal hepatic lesions and should be included in the imaging algorithm for such lesions.

Factitious hosts for Goniozus omanensis (Hymenoptera: Bethylidae), a parasitoid of the lesser date moth Batrachedra amydraula Meyrick (Lepidoptera: Batrachedridae)

ABSTRACT The bethylid wasp Goniozus omanensis has been identified as a key natural enemy of Batrachedra amydraula Meyrick (Lepidoptera: Batrachedridae), an important pest of date palm. Efficient rearing of natural enemies can be an important part of biological pest control programmes but cultures of G. omanensis are challenging to maintain on B. amydraula. We evaluate two readily available species of Pyralid moths, Corcyra cephalonica and Galleria mellonella, as potential factitious hosts. We find that G. omanensis can develop on the larvae of either species, but the probability of failure is circa 75% overall. Both trialled host species were approximately equally suitable, but failures were typically during the early stages of brood production when presented with C. cephalonica and during the later stages when presented with G. mellonella. This suggests that C. cephalonica larvae may be more difficult to suppress and that G. mellonella larvae may be of lower nutritional value. The average production of adult parasitoids per host provided was approximately 1 and, given the observed female biased sex ratio, the average number of females was around 0.8. We suggest potential routes to improving the efficiency of rearing G. omanensis on these factitious hosts.

Interest of toxicological analysis in patients admitted to a pediatric emergency department

Objective: Evaluate the interest of toxicology screening in the management of patients in a pediatric emergency department, by assessing its diagnostic utility. Patients and Methods: This is a retrospective cross-sectional study conducted over two years in the Emergency Department of the Abderrahim Harouchi Mother and Child Hospital, of the Ibn Rochd University Hospital in Casablanca, Morocco. We included all children who underwent qualitative toxicological screening by Gas Chromatography coupled with Mass Spectrometry (GC/MS). A descriptive analysis was conducted on the clinical and toxicological characteristics of the patients. The contingency test allowed us to compare the context of the toxicological screening request and its diagnostic utility. Results: Eighty-seven children were included, with a Male-to Female sex ratio of 1.2. The age of the patients ranged from 1 month to 14 years, with a median of three years. Among the included population, 119 screenings were performed. Drugs were implicated in 27 cases, while 4 pesticide intoxications were found, including carbofuron, chloralose, methomyl and terbucarb, along with 2 cannabis intoxications. A proportion of 88% of screening requests, made in the absence of clinical guidance, turned out to be positive, accounting for 31% (24 cases out of 77) (p<0.001). Conclusion: Toxicological analysis is a valuable tool to assist the clinician in managing intoxications by confirming or excluding the toxic hypothesis. However, toxicological analysis can only be useful and effective, avoiding analytical pitfalls, in the presence of dialogue between the clinician and the analyst.

Transient interruption of contrast on CT pulmonary angiography: effect of mid-inspiratory vs. end-inspiratory respiration command.

To investigate the effects of mid-inspiratory respiration commands and other factors on transient interruption of contrast (TIC) incidence on CT pulmonary angiography. In this retrospective study, 824 patients (mean age, 66.1 ± 15.3 years; 342 males) who had undergone CT pulmonary angiography between January 2021 and February 2023 were included. Among them, 545 and 279 patients were scanned at end- and mid-inspiratory levels, respectively. By placing a circular region of interest, CT attenuation of the main pulmonary artery (CTMPA) was recorded. Associations between several factors, including patient age, body weight, sex, respiratory command vs. TIC and severe TIC incidence (defined as CTMPA < 200 and 150 HU, respectively), were assessed using logistic regression analyses with stepwise regression selection based on Akaike's information criterion. Mid-inspiratory respiration command, in addition to patient age and lighter body weight, had negative association with the incidence of TIC. Only patient age, lighter body weight, female sex, and larger cardiothoracic ratio were negatively associated with severe TIC incidence. Mid-inspiratory respiration commands helped reduce TIC incidence among patients aged < 65 years (p = 0.039) and those with body weight ≥ 75kg (p = 0.005) who were at high TIC risk. Changing the respiratory command from end- to mid-inspiratory levels, as well as patient age and body weight, was significantly associated with TIC incidence.

Difficulties in assessing the medical fitness of workers with mood disorders : A study of 101 cases

IntroductionAssessing the medical fitness of workers with mood disorders remains a topical issue, because of its organizational, socioeconomic and professional impact.ObjectivesTo assess the medical and occupational characteristics of workers with mood disorders.To evaluate the impact of these psychiatric disorders on the medical decision of fitness for work.MethodsDescriptive and retrospective study, over six years (January 1, 2018 to August 30, 2023) including all medical records of workers with mood disorders (bipolar disorder, anxiety disorder, and depression), referred to the occupational department of the Charles-Nicolle Hospital in Tunis for a medical fitness for work.ResultsThe study included 101 patients, mostly female (sex ratio = 0.4), with a mean age of 43.3 ± 9.2 years. The most represented sector of activity was health care. The participants were mainly nurses (25%), followed by technicians (22%) and workers (21%). The mean job seniority was 16.5 ± 9.3 years. A pathological history was found in 74.3% of cases, of which 47.5% were psychiatric disorders. Mood disorders identified in our population were: bipolar disorder (53.5%), anxiety disorder (43.5%), and depression (3%). After medical examination and the decision of treating physician, 39% of the patients (N=39) were declared fit for work, and 31.4% (N=32) were fit with ergonomic adjustments. These accomodations consisted mainly of night shift exemptions in 75% of cases. Temporary unfitness was declared in 24 patients (23.6%). Job mutation was recommended for four patients. Early retirement due to invalidity was proposed for two patients.ConclusionsThe decision on the medical fitness of workers with psychiatric disorders remains a delicate issue that requires the attention of both legislators and occupational health practitioners.Disclosure of InterestNone Declared

Voltinism and life‐history traits of the invasive fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) feeding on corn

AbstractVoltinism and life‐history traits of the invasive fall armyworm (FAW) Spodoptera frugiperda were investigated under semi‐natural conditions for a period of 2 years. The FAW invaded the corn field in the suburbs of Nanchang (28°46′ N, 115°50′ E) in early summer and produced six complete generations. FAW had the characteristics of short developmental time, high survival rates and strong fecundity. The development time of female pupae was significantly faster than that of male pupae, resulting in the emergence of female pupae earlier than male pupae. Except for the sixth generation in 2021, there was no significant difference between female and male sex ratio, which was close to 1:1. FAW showed male‐bias sexual size dimorphism with male pupae being significantly larger than female pupae. Unlike pupal weight, in most generations, male adult weighed significantly less than females, because the weight loss of male pupae during metamorphosis was significantly greater than that of female pupae. The temporal variation of pupal weight did not conform to the temperature–size rule. Compared with 22.8°C, the 29.2°C high temperature not only significantly reduced the development time of larvae but also significantly increased pupal weight. The adult fecundity feeding on fresh corn leaves was higher than that feeding on live corn plants in most generations. In most generations, pupal weight was positively correlated with larval development time and adult weight was positively correlated with fecundity. In conclusion, climate differences between generations and years have significant effects on developmental time, body weight, sexual size dimorphism and fecundity of the FAW. These results add to the understanding of the evolution of life‐history traits in the FAW and may have important implications for predicting population dynamics of the FAW and optimising control strategies.

A retrospective clinico epidemiological study of leprosy cases treated at tertiary care hospital Tirupur

Leprosy is a chronic communicable disease caused by Mycobacterium Leprae. The disease mainly affects the skin, peripheral nerves, mucosal surfaces of the upper respiratory tract, and eyes. Aim is to describe the clinical-epidemiological profile, and type of MDT given for leprosy cases treated at tertiary care hospital Tirupur. A Retrospective study was done by obtaining records of all leprosy patients from the OP Leprosy registration card for a duration of one year from April 2021 – March 2022 were included in the study. The details of patients such as clinical and epidemiological profile were noted and descriptive analysis was done. During the study period, 35 cases of leprosy were included in the study. Majority of the cases were in age group 18 – 45 years. Male female sex ratio was found to be 2.5:1 and no childhood leprosy was recorded. Lepromatous leprosy was the most common type noted in this study. MB MDT was given in most patients. Grade 1 disability was recorded highly than grade 2. Type 1 reaction was found to be more and majority of the cases were noted in local group compared to migratory group. The present study provides an insight into the disease burden as well as the effectiveness of the health-related services at a tertiary care hospital, Tirupur. The study also highlights the early diagnosis and management of leprosy and the importance of the surveillance activity, thereby minimizing the risks of leprosy in Tirupur.