Sex Link Research Articles

Sex and racial disparities in non-alcoholic fatty liver disease-related cardiovascular events: National inpatient sample analysis (2019).

Non-alcoholic fatty liver disease (NAFLD) increases cardiovascular disease (CVD) risk irrespective of other risk factors. However, large-scale cardiovascular sex and race differences are poorly understood. To investigate the relationship between NAFLD and major cardiovascular and cerebrovascular events (MACCE) in subgroups using a nationally representative United States inpatient sample. We examined National Inpatient Sample (2019) to identify adult hospitalizations with NAFLD by age, sex, and race using ICD-10-CM codes. Clinical and demographic characteristics, comorbidities, and MACCE-related mortality, acute myocardial infarction (AMI), cardiac arrest, and stroke were compared in NAFLD cohorts by sex and race. Multivariable regression analyses were adjusted for sociodemographic characteristics, hospitalization features, and comorbidities. We examined 409130 hospitalizations [median 55 (IQR 43-66) years] with NFALD. NAFLD was more common in females (1.2%), Hispanics (2%), and Native Americans (1.9%) than whites. Females often reported non-elective admissions, Medicare enrolment, the median age of 55 (IQR 42-67), and poor income. Females had higher obesity and uncomplicated diabetes but lower hypertension, hyperlipidemia, and complicated diabetes than males. Hispanics had a median age of 48 (IQR 37-60), were Medicaid enrollees, and had non-elective admissions. Hispanics had greater diabetes and obesity rates than whites but lower hypertension and hyperlipidemia. MACCE, all-cause mortality, AMI, cardiac arrest, and stroke were all greater in elderly individuals (P < 0.001). MACCE, AMI, and cardiac arrest were more common in men (P < 0.001). Native Americans (aOR 1.64) and Asian Pacific Islanders (aOR 1.18) had higher all-cause death risks than whites. Increasing age and male sex link NAFLD with adverse MACCE outcomes; Native Americans and Asian Pacific Islanders face higher mortality, highlighting a need for tailored interventions and care.

Extrapulmonary tuberculosis in children under the age of 15 hospitalized at the Pereira Rossell Hospital Center, Uruguay

Tuberculosis is a public health problem. Children constitute a population at risk of becoming ill and evolving into serious forms. To describe the frequency, epidemiological, clinical and evolutionary characteristics of children under 15 years of age hospitalized for extrapulmonary tuberculosis (EPTB) at the Pereira Rossell Hospital-Uruguay, during 2009-2019. Descriptive, retrospective study, review of medical records and records of the Honorary Commission for the Fight Against Tuberculosis. age, sex, epidemiological and clinical link, diagnostic confirmation, treatment and complications. 77 cases of EPTB were registered, 45 (58%) were hospitalized in this center. Average age 7 years, males 25 (56%). All received the Bacillus Calmette-Guérin vaccine. An epidemiological link was identified in 28 (62%). The forms of EPTB were: pleural 26 (58%), central nervous system (CNS) 9 (20%), lymphoganglionic 4 (9%), cutaneous 2 (5%), bone 1 (2%), peritoneal 1 (2%), pleural- peritoneal 1 (2%), bone-CNS 1 (2%). Etiology was confirmed in 23 (51%): by culture 16, GeneXpert 5, by both 2. Thirty-six (80%) patients completed treatment. Four (9%) presented complications: convulsive state 2, cerebral hemorrhage 1, multiple organ failure 1. EPTB occurred in previously healthy children. The diagnosis requires a high index of suspicion and the confirmation of the simultaneous use of several diagnostic techniques.

Testing the drug use and condomless anal sex link among sexual minority men: The predictive utility of marijuana and interactions with relationship status

BackgroundThe association between drug use and condomless anal sex (CAS) is well documented among sexual minority men (SMM). Less is known about whether this association generalizes to marijuana and across relationship status and sexual agreements groups (single, partnered monogamous, partnered open –outside partners permitted, and partnered monogamish –outside partners permitted when main partners are together). MethodsA nationwide sample of SMM (N = 65,707) were recruited through a geosocial networking app between November 2017 and November 2019. Participants reported on drug use and instances of CAS with casual partners in the previous 30 days. ResultsBoth marijuana and club drug use were associated with the occurrence of CAS with casual partners among single men. Only club drug use was associated with CAS frequency in this group. The association between marijuana and the occurrence of CAS did not differ significantly among monogamous men, while the associations between club drug use and the occurrence as well as frequency of CAS were significantly weaker. Meanwhile, the associations between club drug use and the occurrence as well as frequency of CAS did not differ significantly between single and non-monogamous (open and monogamish) subgroups; however, the association between marijuana and the occurrence of CAS was significantly weaker. ConclusionsFindings largely replicated the robust association between club drug use and CAS with casual partners. They support the assertion that marijuana use predicts sexual risk for some SMM subgroups. Finally, they illustrate the potential for relationship status – and sexual agreements – to contextualize associations between drug use and CAS.

Relationship of vitamin D, BMI and BMD in age and gender linked population

&lt;p class="abstract"&gt;&lt;strong&gt;Background:&lt;/strong&gt; Vitamin D insufficiency prevalence has been related to low bone mineral density (BMD). However, controversial results have been reported for the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and BMD. This study was done to investigate whether serum 25(OH)D levels were associated with BMD in different age group and sex link population.&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Methods:&lt;/strong&gt; This study involved, aged 40-70 yr, who is consecutively selected from KPCMCH, BMD camp. BMD was measured at the lumbar spine and femoral neck. The correlation between serum 25(OH)D levels and BMD was investigated.&lt;strong&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Results:&lt;/strong&gt; Vitamin D levels for healthy and patients individuals at hospital. The age of 40 healthy subjects ranged from 40 to 70 years with the average of 55.30±10.30 years and body mass index (BMI) ranged from 18 to 37 kg/m&lt;sup&gt;2&lt;/sup&gt;, with the of average of 28.90±5.20 kg/m&lt;sup&gt;2&lt;/sup&gt;. Comparison between healthy and patients based on BMI and vitamin D level for the overweight BMI healthy individuals was 29.78±9.40 ng/ml, and that of hyperlipidemic patients was 24.47±8.78 ng/ml.&lt;/p&gt;&lt;p class="abstract"&gt;&lt;strong&gt;Conclusions:&lt;/strong&gt; In this study, there is significant different between healthy and patients group in vitamin D&lt;sub&gt;3&lt;/sub&gt;level.BMD significantly decreased in patients group more elderly.&lt;/p&gt;

Aggression and sex link in mice brains

Aggression and sexual behaviorr are controlled by the same brain cells in male mice--but not in females. The finding suggests that males are more likely to become aggressive when they see a potential mate than females. The brain regions that contain these cells look similar in mice and humans, say the researchers behind the study, but they don't yet know if their finding has relevance for human behavior. Similar to humans, male mice are, on the whole, more aggressive than females. Because of this, most research into aggression has overlooked females, says Dayu Lin at New York University.

The human fetal adrenal proteome: development, sex, and maternal smoking link in utero smoke-exposure to offspring disease

The human fetal adrenal proteome: development, sex, and maternal smoking link in utero smoke-exposure to offspring disease

Family Structure, Maternal Dating, and Sexual Debut: Extending the Conceptualization of Instability.

Family structure influences the risk of early onset of sexual intercourse. This study proposes that the family structures associated with risk-single-mother, step-parent, and cohabiting-influence early sexual debut due to family instability, including shifts in family structure and maternal dating, which can undermine parental control and transmit messages about the acceptability of nonmarital sex. Previous research has not considered maternal dating as a component of family instability, assuming single mothers who date and those who do not date experience comparable levels of family disruption and transmit similar messages about the acceptability of nonmarital sex. Hypotheses are assessed using logistic regression models predicting the odds of early onset of sexual intercourse among 9959 respondents (53% female, 47% male) from the National Longitudinal Study of Adolescent to Adult Health. Respondents were ages 12-17 at the first wave of data collection and 18-26 at the third wave, when respondents reported the age at which they first had sexual intercourse. Results show that maternal dating is a source of family instability with repercussions for early sexual debut. Parental control and permissive attitudes towards teenage sex and pregnancy link at-risk family structures and maternal dating to early sexual initiation among females, though these variables do not fully explain family structure and maternal dating effects. Among males, the influence of maternal dating on early sexual debut is fully explained by the learning of permissive sexual attitudes.

Intoxication at last sexual intercourse and unprotected sex among HIV-positive and HIV-negative individuals in Uganda: An event-level analysis

This study examined, for the first time, the association between intoxication at last sexual intercourse and unprotected sex separately among HIV-positive and HIV-negative individuals. Data were derived from a nationally-representative survey of Uganda in 2011. Multivariable logistic regression analyses of the intoxication-unprotected sex association included adjustment for sociodemographic and behavioral covariates that were also examined as moderators of the association. Among HIV-positive individuals, intoxication was associated with unprotected sex, whereas among HIV-negative individuals, the intoxication-unprotected sex association was moderated by knowledge that condoms prevent HIV transmission. The odds of unprotected sex was 2.67 times greater among HIV-negative individuals who were unaware that condoms prevent HIV, an association not observed among those who possessed such knowledge. The results suggest that the intoxication-unprotected sex link be incorporated within Ugandan National HIV Prevention Strategies among HIV-positive and HIV-negative individuals. HIV-negative individuals who are unaware that condoms prevent HIV should be targeted for interventions focusing on increasing HIV transmission knowledge especially on the role of condoms in preventing the disease. The latter interventions should also identify those sociocultural and political beliefs about condom use that may serve as barriers to consistent condom use.

Association between intoxication at last sexual intercourse and unprotected sex among men and women in Uganda.

This study examined the association between intoxication at last sexual intercourse and unprotected sex using data derived from a nationally representative survey conducted in Uganda in 2011. Multivariable logistic regression analyses were used to examine the intoxication-unprotected sex association separately among men and women, adjusted for sociodemographic and behavioral covariates that were also examined as moderators of the association. Among men, intoxication at last sexual intercourse was almost entirely attributed to their own drinking, while women most frequently reported intoxication among their partners only. Among women, there was a significant association between their partner's intoxication and unprotected sex (adjusted odds ratio (AOR) = 1.36; 95% confidence interval (CI) = 1.07-1.73. Intoxication was associated with unprotected sex among unmarried men (AOR = 2.09; 95%; CI = 1.45-2.84), an association not observed among married men. The results suggest that the alcohol-unprotected sex link should be incorporated within Ugandan National HIV Prevention Strategy. These interventions should be designed to target unmarried men. Programs that combine alcohol reduction and address structural factors that constrain women's ability to negotiate condom use are also needed.

Intoxication at last sexual intercourse and unprotected sex among HIV-positive and HIV-negative individuals in Uganda: an event-level analysis.

This study examined, for the first time, the association between intoxication at last sexual intercourse and unprotected sex separately among HIV-positive and HIV-negative individuals. Data were derived from a nationally-representative survey of Uganda in 2011. Multivariable logistic regression analyses of the intoxication-unprotected sex association included adjustment for sociodemographic and behavioral covariates that were also examined as moderators of the association. Among HIV-positive individuals, intoxication was associated with unprotected sex, whereas among HIV-negative individuals, the intoxication-unprotected sex association was moderated by knowledge that condoms prevent HIV transmission. The odds of unprotected sex was 2.67 times greater among HIV-negative individuals who were unaware that condoms prevent HIV, an association not observed among those who possessed such knowledge. The results suggest that the intoxication-unprotected sex link be incorporated within Ugandan National HIV Prevention Strategies among HIV-positive and HIV-negative individuals. HIV-negative individuals who are unaware that condoms prevent HIV should be targeted for interventions focusing on increasing HIV transmission knowledge especially on the role of condoms in preventing the disease. The latter interventions should also identify those sociocultural and political beliefs about condom use that may serve as barriers to consistent condom use.

A classical Mendelian cross-breeding study of the Naples high and low excitability rat lines

The development of brain and behaviour is controlled by the interaction of genetic determinants and environmental factors. To study genetic determinants, model systems such as the Naples rat lines, i.e. Naples high (NHE) and low excitability (NLE), are useful. They have been selectively bred for divergent behaviour arousal to novelty. Aim of this study was to assess the extent of the genetic control of the selection trait. Thus adult albino rats of NHE and NLE lines have been used throughout. According to a classical Mendelian cross-breeding design, a first experiment was carried out with hybrids obtained from parental lines P1 (NHE) and P2 (NLE) as F1, F2 and related backcrosses B1 (F1 × P1) and B2 (F1 × P2). Young adults (60–80 days) offspring of both gender were exposed separately for two 10 min tests to a spatial novelty (Lát-maze). To verify a possible sex link of the trait, a second experiment was carried out adding to the Mendelian cross design parental gender. Behavioural variables were horizontal (corner-crossings: HA), vertical (rearings on hindlimbs: VA) or total activity (HVA: HA + VA) scores. The heritability of HVA trait was estimated across the 20 generations of selection and Mendelian cross hybrids. Quantitative-genetic analysis on this trait and its HA and VA components, was applied by the Lynch and Walsh joint-scaling test procedure to evaluate underlying genetic mechanism. The correlation between experimental data of hybrids and estimated values from different heritability models were also computed. Results indicated that (i) the activity scores by Mendelian hybrids were intermediate between the two parental lines and were also graded; (ii) there was no sex effect on the heritability of trait but only a general tendency of females to higher activity levels; (iii) the heritability of HVA trait was very high ( h 2 index = 0.824); (iv) heritability model of HVA and HA trait was polygenic with a marked epistatic control where as VA trait was fitted by simpler model with less genes and lower epistatic effect. In conclusion the Naples lines reveal strong genetic determinants for behavioural traits associated with polygenic pattern. Moreover, HA and VA activity components with prevailing cognitive and non-cognitive meaning, respectively, show differential genetic control.

Indulgence or restraint? Gender differences in the relationship between controlled orientation and the erotophilia-risky sex link

The present research evaluated the relationships among controlled orientation, erotophilia, and risky sexual behavior. Erotophilia was expected to be positively associated with risky sexual behavior and the link between erotophilia and risky sexual behavior was expected to be stronger among more controlled individuals, especially for men. Participants ( N = 111: 64 women, 47 men) completed self-report measures of self-determination, erotophobia–erotophilia, and risky sexual behavior. Being more controlled was associated with engaging in more risky sexual behavior, and for men, a stronger link between erotophilia and risky sex. Results suggest that favorable attitudes and responses to sexual cues are more strongly associated with risky behaviors among individuals who are more controlled. Differential norms for men and women regarding the acceptability of risky sexual behavior are probable moderators of the stronger erotophilic-risk link among more controlled individuals.

The Naive Misuse of Power: Nonconscious Sources of Sexual Harassment

Sexual harassment is considered from the perspective of power abuse in general. Recent research on sexually aggressive men has underscored the importance of power and dominance as a motivator of their behavior toward women. One striking feature of both sexual harassment and the misuse of power is the lack of awareness offenders often show regarding the inappropriateness of their actions. This lack of awareness is similar to automatic or nonconscious effects demonstrated in social perception and judgment research, such as the unintentional influence of one's stereotypes informing impressions of others. The possibility that having power within a situation automatically and nonconsciously triggers a sexuality schema, just as racial or gender features automatically trigger stereotypes of that group, is discussed and supporting research is described. It is shown, for example, that for men likely to sexually harass, merely activating the concept of power without their knowledge causes them to find the same woman more attractive. The possible origins of the automatic power → sex link, and its implications for preventing sexual harassment behavior, are discussed.

Changes in plasma testosterone levels during the peri-hatching period in the chicken

Blood was obtained by heart puncture from 19-day-old Black Sex link chicken embryos and from Black Sex link chickens at 1.5,6, or 24 h post-hatching. Plasma testosterone was determined by gas chromatography-mass spectrometry associated with stable isotope dilution. At 19 days the plasma of male and female chick embryos contains measurable amounts of testosterone and levels do not differ between sexes. After hatching plasma testosterone gradually declines from pre-hatch concentrations in males and females, but in all the post-hatch ages studied, plasma testosterone was significantly higher in male than in female chicks. These results indicate that in male chickens, contrary to mammals at birth, there is no surge in plasma testosterone at hatching.

Effects of Early Maturation, Layer Protein Level, and Methionine Concentration on Production Performance of Brown-Egg-Type Pullets

Three hundred and sixty 17-week-old Harco Sex Link pullets were transferred to laying cages and received 13 hr of light daily for the first week followed by 15 hr the second and subsequent weeks. A second group of 360 pullets remained in the growing facility on 8 hr of light until 19 weeks of age when the light was increased to 13 hr. At 20 weeks these birds were transferred to the laying facility where they received 15 hr of light daily for the duration of the experiment. A 15% protein grower ration was fed until daily production of each group reached 2%, at which time the diets were changed to either a 17 or 19% protein layer ration, each supplemented with DL-methionine so as to contain .3 or .4% total methionine.Early housed pullets averaged 140.4 days at first egg whereas late housed reached sexual maturity at 149 days. The initial increase in egg production by the early housed pullets was followed by a more rapid decline and overall, from housing to 66 weeks, equivalent egg numbers were produced. The early housed pullets were less efficient than the late housed birds due in part to their larger body mass. The greater percentage of small and medium-sized eggs produced by the early housed birds was not influenced by increasing the concentration of protein or methionine in the layer ration.

Feed Restriction in Laying Hens

Brown egg Sex Link and White Leghorn laying birds were full fed, restricted 5 and 10%, and time restricted with the goal of restricting feed 10%. The production of the restricted Sex Links ranged from 5.3 more eggs per bird than the full fed to a maximum of 10.3 less eggs per bird. The restricted White Leghorns ranged from 2.8 more eggs per bird than the full fed to a maximum of 10.5 less eggs per bird.Feed restriction at the levels tested did not significantly affect mortality, but average egg size was reduced from 62.1 g in the full fed Sex Links to 60.4 g and 60.9 g, respectively, for the 10% and time restricted groups. In the White Leghorns the corresponding egg size figures were 58.6 g for the full fed and 57.2 g and 57.3 g for the other two groups. Difference in egg size in both types of hens between the various treatments was significant at the P≤.05 level.The total body weight gain during the laying year was approximately 30% less with the restricted groups.

LINGUISTIC THEORY AND THE REAL WORLD1

Traditionally, applied linguists have looked to theoretical linguistics for help, and not vice versa, and they haven't found much enlightenment. Recent work by theoretical linguists on the interaction between language use and real world phenomena may begin to change this situation. Language teachers have realized that some aspects of language are harder to teach than others: the use of particles like “well,” hedges like “sort of,” and “I guess,” sex link uses of various sorts, and forms marking levels of politeness. Although analogues are found between languages, exact parallelism between a form and its function in two languages seldom exists. Theoretical linguistics is becoming able to formalize the properties of this area of language use. Its discoveries could aid teachers in explaining the uses of these forms. Conversely, there is much not yet understood by theory. For one thing, we don't know which of the properties of these forms are universal. Applied linguists know where second‐language learners make mistakes and what kind of errors they make. The nature of these errors should prove a diagnostic aid to theorists, showing what is common to all languages and what is not. Thus, in this area as in many others, progress can best be made by theoretical and applied linguists if they will work together as equal partners.