We report a near term live birth of a child prenatally diagnosed with Patau’s syndrome, rare case reaching this gestational age. Despite the acknowledgement of the poor fetal prognostic the parents chose to accept the natural course of the affected pregnancy, decision based on religious considerations. Alobar subtype of holoprosencephaly associating facial dysmorphism along with severe cardiac and limb defects and ambiguous genitalia were the main ultrasonographic and clinical findings. We describe a particular phonotypical association for a full aneuploidy that have been early prenatal diagnosed.