Abstract EFSA received a request from the European Commission to provide support for the preparation of the EU position for 53rd Session of the Codex Committee on Pesticide Residues (CCPR). In 2021, JMPR evaluated 38 active substances with regard to their toxicological properties and/or the setting of Codex Maximum Residue Limits (CXLs) (acetamiprid, bixafen, clofentezine, clothianidin, cyprodinil, difenoconazole, ethion, ethiprole, fenbuconazole, fenhexamid, fenpicoxamide, fenpyroximate, fipronil, fluopyram, flutianil, imazalil, isoprothiolane, isoxaflutole, mandipropamid, mefentrifluconazole, metalaxyl, metalaxyl‐M, methoprene, methoxyfenozide, pendimethalin, prothioconazole, pydiflumetofen, pyrasulfotole, pyraziflumid, quinoxyfen, spinetoram, spiropidion, sulfoxaflor, tebuconazole, tetraniliprole, thiamethoxam, trifloxystrobin, trinexapac). EFSA prepared comments on the Codex MRL proposals and the proposed toxicological reference values. In addition, EFSA provided further considerations on follow‐up assessments of JMPR on pesticides for which specific concerns on the toxicological or residue assessments were raised in the previous CCPR meetings (afidopyropen, fluensulfone, metconazole, propiconazole). The current report should serve as the basis for deriving the EU position for the CCPR meeting.
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