Serology For Toxoplasmosis Research Articles

A Case Report of Ocular Toxoplasmosis Associated with Chagas Disease and Literature Review

Introduction: Ocular toxoplasmosis (OT) is one of the most frequent clinical manifestations of toxoplasmosis infection. Likewise, another relatively common chronic parasitic condition in Colombia is Chagas disease (CD). At present, there is little information about patients living with CD and other chronic parasitic conditions such as toxoplasmosis; therefore, this report aims to present a case of OC in a patient with chronic CD. Clinical case: A patient recently diagnosed with CD, chronic phase with cardiac involvement, consulted for decreased visual acuity accompanied by placoid chorioretinitis in the macula with an active retinitis zone adjacent to the placoid chorioretinitis. 2+ vitreous cells were present with a headlight in the fog sign. Anterior chamber cells were 1+. As serology (IgM, IgG) for toxoplasmosis was positive, OT was diagnosed. With this diagnosis, treatment was started with trimethoprim-sulfamethoxazole, clindamycin, and prednisone, after which the lesion resolved, leaving an atrophic scar. Visual acuity improved. During 24 months of follow-up, no recurrences were observed. The patient continued clinical follow-up for CD. Conclusion: The clinical features of this patient appear to be similar to those without this coinfection. It also shows several commonly encountered features of OC and the resolution of symptoms using a relatively standard therapy.

Toxoplasmosis outbreak in São Paulo, Brazil: Epidemiology and visual outcome.

To describe a 2019 acute toxoplasmosis outbreak in the city of São Paulo, Brazil, and to evaluate the laboratory serological profile for toxoplasmosis for three consecutive years. The ophthalmological manifestations of the patients involved in the outbreak were also studied. A cross-sectional descriptive study of a toxoplasmosis outbreak in São Paulo, Brazil, between February and May 2019. Epidemiological data were described, as were the observed ocular manifestations. As part of this study the number of patients with positive IgM toxoplasmosis serology was obtained from a large laboratory network (DASA) for three consecutive years, including the year of the outbreak (2018, 2019, 2020). Eighty-three individuals were identified in the outbreak and two clusters were studied. The clinical picture of at least 77% of the patients, the epidemiological analysis, and the short incubation period (5-8 days) suggested contamination by oocysts. Serological laboratory data analysis revealed an increase of positive toxoplasmosis IgM in 2019 of 73% compared to the previous year. Ophthalmological examination revealed that at least 4.8% of the patients developed toxoplasmic retinochoroiditis, none of whom had been treated during the acute systemic disease. Our findings indicate vegetable contamination as the possible source of this outbreak, a high prevalence of toxoplasmosis in São Paulo during the outbreak period, and a drop in the number of tests during the COVID-19 pandemic. Retinochoroiditis was observed in at least 4.8% of the cases. We confirm the need to implement effective means for the prevention, diagnosis, and treatment of the disease. This may involve raising awareness among the population of the importance of vegetable hygiene, and improved quality control of food and water.

Seroprevalence of Toxoplasma gondii IgG and IgM antibodies and associated risk factors among pregnant women consulted in three health centers in Dschang, Cameroon

BackgroundToxoplasmosis is a zoonosis caused by Toxoplasma gondii, an obligate intracellular protozoan responsible for one of the most common congenital infections in the world. This study aimed to determine the seroprevalence and risk factors associated with toxoplasmosis in pregnant women consulted in three health centers in the city of Dschang. MethodsThis study was a cross-sectional study that was conducted, with a total of 242 participants. A questionnaire was administered after obtaining the free and informed consent of the participants. Blood sample was collected to assay IgG and IgM antibodies specific to Toxoplasma gondii using the enzyme-linked immunosorbent assay (ELISA) kit, and potential risk factors were evaluated with the administration questionnaire using a binary logistic regression model. Statistical significance was measured at P < 0.05. ResultsThe overall seroprevalence of toxoplasmosis was 82.7%,with a seroprevalence of toxoplasma IgG of 62.8% (152), that of IgM at 11.6% (28) and that of IgG/IgM at 8.3% (20). The Saint Vincent Paul Hospital had a seroprevalence of 43.8% IgG and 8.7% IgM; followed by the Dschang District Hospital (11.6% IgG and 2.1% IgM). The seroprevalence of toxoplasma IgG (35.5%) and IgM (6.2%) was higher in multiparous pregnant women, and in the group of women who performed their first toxoplasmosis serology in the first trimester of pregnancy, 70 (28.9%), 9 (3.7%) respectively for IgG and IgM. The multivariate logistic regression analysis showed that the possession of a cat at home or its presence in the neighborhood, the consumption of undercooked or uncooked meat and having a history of blood transfusion were found to be statistically significant risk factors associated with toxoplasmosis seroprevalence among pregnant women. ConclusionThe present study revealed a high seroprevalence of toxoplasmosis. Given this high seroprevalence, screening for toxoplasmosis in women of childbearing age should be encouraged.

Anti-Toxoplasma IgM-IgG Titer in Malignancy Patients Receiving Chemotherapy at Dr. H Abdul Moeloek General Hospital of Lampung Province

Transmission of toxoplasmosis is influenced by interacting disease agents, hosts and environmental conditions. Nutritional status is a host factor that cannot be ignored. Some studies suggest that high body mass index has a strong association with Toxoplasmosis. This study aims to analyze anti-toxoplasmosis IgM and IgG titers based on nutritional status in patients with malignancies who receive chemotherapy at the Lampung Provincial General Hospital, Indonesia. The design of this study was cross-sectional. The population of this study were malignancy patients who received chemotherapy with or without symptoms of infection at Lampung Provincial Hospital. Blood samples were examined for Toxoplasmosis serology to measure IgG and IgM titers. Examination with CMIA technique. Data analysis was done descriptively followed by Anova or Kruskal Wallis test. The results of this study showed that there were no differences in mean age, IgM and IgG titers in the three nutritional status groups.

ORAL SYPHILIS IN AN ADULT PATIENT WITH AN INITIALLY VDRL NEGATIVE TEST

We report an uncommon presentation of oral syphilis in a male patient, 29 years old with a 2-month mouth ulcer. Clinical examination showed right submandibular lymphadenopathy and a painless ulcer located on the right labial commissure. Serology was requested for syphilis (VDRL) and HIV—both nonreactive—and a complete blood count that showed no changes. An incisional biopsy was performed with a diagnosis of an inflammatory process. Histochemical stains, such as Ziehl Nielsen and PAS, were requested, in addition to serology for toxoplasmosis and histoplasmosis, which were all nonreactive. Two months later, due to the persistence of the lesion, FTA-ABS and VDRL were requested again, and both were positive, characterizing syphilis. Afterward, treatment with benzathine penicillin 1,200,000 UI (2 applications/3 weeks) was proposed, and the patient remains in follow-up.

Ocular toxoplasmosis in infants 0 to 12 months of age with congenital toxoplasmosis

Ocular toxoplasmosis (OT) is a retinochoroiditis that evolves with several episodes of inflammation and can occur both in the congenital or acquired form of the disease, Aim: To describe the frequency and clinical characteristics of OT in infants aged 0 to 12 months, children of mothers with positive serology for toxoplasmosis in the perinatal period. Cross-sectional descriptive, ambispective study. Infants from 0 to 12 months of age, whose mothers had positive serology for toxoplasmosis in the perinatal period, referred to the pediatric ophthalmology service for evaluation, were admitted. Demographic variables, maternal and infant serology and the results of the ophthalmological examination were collected. Data were analyzed in SPSS v21 Results: 46.4% of 125 infants had OT, of them 67.2% were female, (p = 0.04) the median age was 6 months, 41% had IgG and IgM positive. The lesions were bilateral in 82.8%, central in 86.2%, and inactive in 81%. Retinochoroiditis was accompanied by strabismus in 41%. The frequency of OT in this population of infants with congenital toxoplasmosis was high. more than 80% of the eye lesions were inactive, centrally located and bilaterally involved.

An Unusual Presentation of Glandular Fever

Epstein-Barr virus (EBV) is an ubiquitous DNA herpesvirus with >90% of adults >40 years of age showing a serological response. While in their youth, primary EBV infection may pass unnoticed, young adults have a high incidence of infectious mononucleosis (IM). This is characterized by a triad of pharyngitis, cervical lymphadenopathy, and fever because of a self-limiting lymphoproliferative disease. Common complications include but are not limited to hepatitis, splenomegaly, encephalitis, and haemophagocytic lymphohistiocytosis (HLH) with evidence that Caucasian males and smokers are more likely to suffer severe disease. Here we present a 21-year-old male who presented with a 2-week history of fever, dry cough, and a 4-week history of pharyngitis. He had no exposure to unwell contacts and denied any new sexual partners. Examination revealed general pallor with tender bilateral cervical lymphadenopathy and pharyngeal erythema. Admission bloods revealed pancytopenia (WCC 1.5 × 109/L, Plt 84 × 109/L, and Hb 82 g/L) with normal reticulocyte count and raised mean corpuscular volume (114 fL). Serum vitamin B12 and folate were low with serum ferritin raised (1027 µg/L) suggesting a proinflammatory state. Admission liver function tests, coeliac serology, autoimmune panel (ANA, ANCA, and anti-dsDNA), hepatitic (hepatitis A, B, and E), human immunodeficiency virus (HIV), toxoplasmosis, parvovirus, and CMV serology were normal. The monospot test on day 1 of the presentation was negative. Ultrasound (US) of the abdomen on day 3 of the presentation revealed isolated splenomegaly (16.8 cm). Day 4 EBV serology (VCA IgM, VCA IgG, and EBNA IgG) was negative as such haematological investigations including JAK2, serum free light chains, and BCR-ABL were undertaken alongside cervical lymph node core biopsy. Repeat Monospot testing on day 7 came back positive. Repeat EBV serology now showed equivocal EBV VCA IgG (0.77 OD) and positive VCA IgM (9.04 OD) with concurrent new hepatitis. Histopathology of the core biopsy revealed Sternberg-reed cells and a mixed immunoblastic reaction in keeping with resolving IM. This case highlights the need for physicians to have a strong clinical suspicion of IM and understand the multiple ways in which IM may be present as well as the time lag to positivity in serological testing.

Ultra-wide field imaging for ophthalmological evaluation of pregnant women with positive serology for toxoplasmosis

Ultra-wide field imaging for ophthalmological evaluation of pregnant women with positive serology for toxoplasmosis

Three-Year Clinical Follow-Up of Children Intrauterine Exposed to Zika Virus.

Congenital Zika virus (ZIKV) infection may present with a broad spectrum of clinical manifestations. Some sequelae, particularly neurodevelopmental problems, may have a later onset. We conducted a prospective cohort study of 799 high-risk pregnant women who were followed up until delivery. Eighty-three women and/or newborns were considered ZIKV exposed and/or infected. Laboratory diagnosis was made by polymerase chain reaction in the pregnant mothers and their respective newborns, as well as Dengue virus, Chikungunya virus, and ZIKV serology. Serology for toxoplasmosis, rubella, cytomegalovirus, herpes simplex virus, and syphilis infections were also performed in microcephalic newborns. The newborns included in the study were followed up until their third birthday. Developmental delay was observed in nine patients (13.2%): mild cognitive delay in three patients, speech delay in three patients, autism spectrum disorder in two patients, and severe neurological abnormalities in one microcephalic patient; sensorineural hearing loss, three patients and dysphagia, six patients. Microcephaly due to ZIKV occurred in three patients (3.6%). Clinical manifestations can appear after the first year of life in children infected/exposed to ZIKV, emphasizing the need for long-term follow-up.

Seroprevalencia de chagas y toxoplasmosis en pacientes con enfermedades reumatológicas. Informe preliminar

Introduction: The use of biological therapy has been associated with an increased risk for different types of infections. In this sense, the development of strategies for prevention and treatment of infections in patients with rheumatic diseases with biological therapy is essential. Currently there is little information on the seroprevalence of Chagas disease (CD) and toxoplasmosis in patients with rheumatic diseases. Objective: To analyze the seroprevalence of CD and toxoplasmosis in patients with rheumatic diseases in plans to start BT. Methodology: Retrospective study of patients with rheumatic diseases whit criteria to start a BT in the Rheumatology Service of the IPS Central Hospital. Clinical, epidemiological, serological and treatment-related variables were recorded. The frequency of positive serology for CD and toxoplasmosis was analyzed and the association with the collected variables was studied. Results: 228 patients were included (RA = 176, Sp = 43, Collagenopathy = 9), 74.6% were women with a mean age of 46.2 years. Chagas seroprevalence was 2.9% and toxoplasmosis 63.1%. No significant associations were identified with the analyzed variables. Conclusion: The seroprevalence of toxoplasmosis and Chagas disease was similar to that described in studies of the general population of our country and the region, so it is important to always keep them in mind especially in developing countries.1Q In the present study, a reactivation of the disease after the onset of BT was not found.

Adequacy of Prenatal Care in Northeast Brazil: Pilot Data Comparing Attainment of Standard Care Criteria for First-Time Adolescent and Adult Pregnant Women.

BackgroundAdolescent pregnancy is a public health concern worldwide, particularly in low-income settings. Adolescent mothers face higher risks during pregnancy and delivery compared to adult mothers and yet, may also experience worse quality of obstetrical care. This study evaluates adherence to meeting Brazilian recommendations for prenatal care by comparing first-time adolescent versus adult mothers in a rural, low-income setting.MethodsUsing data from the Adolescence and Motherhood Research (AMOR) project, we evaluated adherence to national recommendations as documented in the prenatal cards of 39 adolescents (13–18 years) and 37 adults (23–28 years) from a low-income area in northeast Brazil. Recommendations included ≥6 prenatal consultations, gestational age ≤12 weeks at the first visit, participation in 3 educational activities, 2 serology for syphilis (VDRL) and HIV, 1 Toxoplasmosis serology, 2 urine tests, 2 blood glucose and 2 hemoglobin/hematocrit (Hb/Ht) exams. Chi-square tests were used to compare the proportions of adolescents and adults with a record of these procedures in the prenatal cards.ResultsCompared to adult women, the adolescent group had lower attainment of almost all recommended components of prenatal care compared to the adult group, with statistically significant differences for 2 blood glucose tests (46.2% vs 78.4%; p=0.004), 2 VDRL tests (30.8% vs 54.1%; p=0.040), 2 Hb/Ht exams (35.9% vs 83.8%; p<0.001), and at least 6 consultations (84.6% vs 100%; p=0.013).ConclusionDespite greater health risks of adolescent fertility, the prenatal cards of adolescent mothers presented a poorer record of adherence to recommendations for adequate prenatal care compared to adult mothers from a low-income setting of Brazil. Health policies for both health professionals and the target population are needed to ensure adequacy of prenatal care and appropriate risk reduction for this vulnerable population.

Clinical Significance of Hyperechogenic Bowel in Second-Trimester Ultrasound Scan

Background: This study aimed to report the incidence of bowel obstruction, chromosomal abnormality, congenital infection, fetal growth restriction (FGR), and otheranomalies in fetuses with hyperechogenic bowel (HEB) diagnosed during the second-trimester fetal ultrasound scan.Methods: In total, 350 fetuses with a diagnosis of HEB in our maternal-fetal medicine referral center were evaluated with a detailed fetal ultrasound examination by an experienced perinatologist. If no associated anomalies were observed, women were counseled about the risk of potential fetal disorders and offered appropriate testing, including detailed fetal sonography, karyotype, maternal cytomegalovirus (CMV), and toxoplasmosis serology,as well as serial fetal biometry and bowel diameter follow up.Results: Altogether there were 18(5.1%) fetuses with associated problems, including major anomalies, chromosomal abnormalities, and CMV infection. Moreover, 32(9.1%) fetuses developed FGR during follow-up.Conclusion: An overall rate of adverse conditions of 14.2% with prenatally detected HEB serves to inform obstetricians and emphasizes the importance of careful screening fetal ultrasound studies and timely referral for an additional assessment about associated findings.It should be noted that isolated HEB has good outcomes.

CESTODE INFECTION IN THE PAROTID LYMPH NODE

A 14-year-old patient presented with a complaint of “left ear lump,” associated with a history of fever and 1 month of evolution, and not responding to broad spectrum antimicrobials. At the echoscopic examination, there was evidence of a nodular lesion in the left parietal region, sessile, with a fibroelastic consistency. Initially, the hypotheses were salivary gland inflammation or infectious disease. Exfoliative cytology and hemogram and serum serology for HIV, rubella, cytomegalovirus, toxoplasmosis, and venereal disease research laboratory test were requested, as well as a computed tomography scan of the skull with contrast. The hematologic and serologic tests were normal; however, the cytopathology showed a nonspecific chronic inflammatory infiltrate and structures compatible with eggs and body of a developed cestode. The tomographic examination ruled out neurocysticercosis. The treatment consisted of praziquantel, ceftriaxone, and supportive medications for 15 days, followed by the surgical excision of the lesion. Currently, he is being followed up with complete remission of the lesion, without significant surgical sequelae. A 14-year-old patient presented with a complaint of “left ear lump,” associated with a history of fever and 1 month of evolution, and not responding to broad spectrum antimicrobials. At the echoscopic examination, there was evidence of a nodular lesion in the left parietal region, sessile, with a fibroelastic consistency. Initially, the hypotheses were salivary gland inflammation or infectious disease. Exfoliative cytology and hemogram and serum serology for HIV, rubella, cytomegalovirus, toxoplasmosis, and venereal disease research laboratory test were requested, as well as a computed tomography scan of the skull with contrast. The hematologic and serologic tests were normal; however, the cytopathology showed a nonspecific chronic inflammatory infiltrate and structures compatible with eggs and body of a developed cestode. The tomographic examination ruled out neurocysticercosis. The treatment consisted of praziquantel, ceftriaxone, and supportive medications for 15 days, followed by the surgical excision of the lesion. Currently, he is being followed up with complete remission of the lesion, without significant surgical sequelae.

Comparison of the Toxogen® rapid test with ELISA immunoenzymatic technique for toxoplasmosis serology in pregnant women

The aim of this study was to compare the technical performance of the Toxogen® rapid test against the ELISA technique for serological screening and/or serological monitoring of toxoplasmosis in pregnant women. Methods and material: A prospective, descriptive and analytical study was conducted over a period of 7 months from January to July 2018. One hundred and eighty-two toxoplasmosis serologies were carried out on 144 pregnant women followed in two hospitals in Mahajanga and in a private laboratory in Antananarivo. Two serologies were performed for each case, the first by the rapid test Toxogen®, a latex agglutination test, and the second by the IgG-ELISA and IgM-ELISA technique. Results: The Toxogen® rapid test had a sensitivity of 62.5%, a specificity of 97.1%, a Positive Predictive Value of 94.3%, a Negative Predictive Value of 76.7% compared to the IgG-ELISA technique. The correlation between the dilution titer by the Toxogen® rapid test and the optical density (OD) of anti-toxoplasmics IgG by the ELISA technique was very low (r² = 0.17, p <0.001). The crude prevalence of toxoplasmosis was 30,6% (n=44) by the Toxogen® rapid test and 46.5% (n=67) by the IgG-ELISA technique, the difference was significant (p <0.001). We had 2 cases (0.01%) positives by the IgM-ELISA which were not detected by the Toxogen® rapid test. Conclusion: The Toxogen® rapid test cannot substitute the ELISA technique for the serological screening and/or serological monitoring of toxoplasmosis in pregnant women.

Ocular Findings in Infants with Microcephaly Caused by Presumed Congenital Infection by Zika Virus in Sergipe.

This study aims at identifying ocular findings in infants with microcephaly associated with presumed intrauterine infection by ZIKV. A cross-sectional study included 62 outpatient infants with congenital microcephaly, presumably secondary to maternal ZIKV infection. The included infants had head circumference below −2 standard deviations, with negative maternal serology for toxoplasmosis, rubella, cytomegalovirus, syphilis, and HIV. Assessment of ocular alterations was performed through review of their medical records. Forty two (67.7%) of the children analyzed presented some degree of ocular alteration. Findings in the posterior segment occurred in 29 (46.8%) patients, including atrophy of the retinal pigmentary epithelium in 15 (24.2%) patients, chorioretinal scars in 14 (22.6%) patients, retinal coloboma in 6 (9.7%) patients, and punctate retinal hemorrhage in 1 (1.6%) patient. Other ocular alterations were seen in 15 (24.2%) patients, including pathological strabismus in 11 (17.7%) patients, congenital cataracts in 2 (3.2%) patients, and nystagmus in 2 (3.2%) patients. Functional alterations were seen in four (6.5%) children. More than one change occurred in 11 (17.7%) children, eight of whom had head circumferences below −3 standard deviations. Changes in both the eyes occurred in 22 (35.5%) children, while 20 (32.3%) children had unilateral involvement. Among the 42 children with any ocular alteration, 27 (64.3%) children presented with severe microcephaly (head circumference with standard deviation lower than −3). The majority of children with microcephaly, presumably secondary to maternal ZIKV infection, present ocular alterations, with a higher frequency of involvement in the fundus. Severe ocular alterations are related to severe microcephaly.

Seroprevalence of toxoplasmosis in pregnant women of the Marrakech-Safi region, Morocco.

Toxoplasmosis is a parasitic infection caused by an intracellular protozoan named Toxoplasma gondii. Its prevalence had been investigated in several studies throughout the world showing that it varied from one country to another. In contrast, few studies had been carried out on this infection across the kingdom of Morocco, hence the objective of this work, which is the determination of Toxoplasma gondii seroprevalence in the region of Marrakech-Safi. The serological results of a cohort of 5692 patients were reviewed retrospectively. Those patients had been into different public and private medical laboratories in the region of Marrakech-Safi for a toxoplasmosis serology, requested between the 1st January, 2014 and 31st December, 2016. According to each laboratory, the techniques adopted for this serology were ELISA (ELFA, MEIA, EIA) and CMIA. The results showed that for pregnant women, the overall seroprevalence in the study region were 28.88%. The variation of Toxoplasma gondii seroprevalence is related not only to climatic factors but also to lifestyle, eating habits, socio-economic status and hygiene conditions. In this study, we noticed that in Morocco, as in other countries, pregnant women encounter several difficulties when serologic screening for toxoplasmosis.

Clinico-epidemiological and sociodemographic profile of HIV/AIDS patients who are co-infected with Toxoplasma gondii in the border region of Brazil.

The present study assessed clinico-epidemiological and sociodemographic characteristics and risk factors for human immunodeficiency virus (HIV) in patients who were co-infected with T. gondii in the border region of Brazil. HIV-positive patients who were attended by the Expert Assistance Service in Foz do Iguaçu city were assessed using a questionnaire and medical records. Of the 332 patients with HIV/autoimmune deficiency syndrome (AIDS) who were evaluated, 111 had serology for toxoplasmosis, which could be attributed to the location of the city (i.e., border region) and tourism that encourages the intense flow of people. Toxoplasmosis infection was prevalent among patients who were 18-60 years old, had education up to the 4th grade of elementary school, ate raw vegetables from home, handled soil without gloves, drank untreated water, and allowed street cats to enter their homes. These findings contribute to assessments of the toxoplasmosis profile of HIV/AIDS patients who have a high rate of toxoplasmosis. The results may contribute to improving public health, especially in border regions with characteristics that are similar to this study. Effective measures need to be implemented to control morbidity and mortality that are associated with HIV/AIDS and toxoplasmosis in the evaluated population.

Acute lymphocytic leukemia associated with toxoplasmosis: case report

ABSTRACT Rare clinical case of acute lymphocytic leukemia (ALL) associated with toxoplasmosis affecting a 23-year-old male patient with progressive dyspnea. Chest computed tomography revealed expansive lesions indicating right supraclavicular fossa lymph node enlargement and right pleural effusion. Toxoplasmosis serology was performed: positive for immunoglobulin G [(IgG) 180.6] and positive for immunoglobulin M [(IgM) 0.98]. Therefore, treatment for the infection was initiated and immunohistochemistry of left cervical lymph node revealed ALL. Consequently, chemotherapy treatment was introduced at an oncology center. The diagnosis of toxoplasmosis allowed treatment to be administered, preventing the worsening of the condition caused by chemotherapy-induced immunosuppression.

Toxoplasmose: assistência pré-natal sob a abordagem da rede cegonha em Itaparica-Bahia-Brasil entre 2013 a 2016

Introdução: A toxoplasmose é uma doença infecciosa de grande importância clínica para gestantes devido à possibilidade de transmissão congênita. A rede cegonha é uma estratégia utilizada para assistência ao pré-natal inserida na atenção básica à saúde, tem finalidade de reduzir índices de mortalidade materna e neonatal.Objetivo: Estabelecer a relação entre o processo de diagnóstico sorológico para toxoplasmose em gestantes e a atuação da rede cegonha.Materiais e Métodos: Trata-se de um estudo de caráter descritivo retrospectivo de base documental, constituído por 461 prontuários de gestantes atendidas no período de 2013 a 2016 no município de Itaparica/BA. Abordam dados clínicos e epidemiológicos das gestantes inseridas na rede cegonha e vinculadas a uma das unidades de saúde da família de Itaparica/BA.Resultados: Foram identificadas 302 (65,5%) gestantes que realizaram sorologia para toxoplasmose, sendo que 3,65% foram susceptíveis, 11,6% imunes, 1,3% com possível infecção aguda e 83,45% tiveram perfil clínico inconcluso para toxoplasmose.Conclusão: A rede cegonha facilita o acesso ao acompanhamento pré-natal e diagnóstico sorológico. No entanto, há dificuldades no que se refere à realização de exames que auxiliem a conclusão diagnóstica.

Fatores de risco maternos para toxoplasmose numa maternidade pública do nordeste do brasil

Introduction: Vertical transmission by Toxoplasma gondii usually occurs in women who are infected for the first time during pregnancy. Screening for toxoplasmosis during pregnancy is one of the measures adopted in our country as a form of prevention. Objective: To investigate maternal risk factors associated with gestational toxoplasmosis in a large maternity hospital located in Fortaleza-Ceará. Methodology: This is an observational, quantitative comparative study conducted in a federal public maternity hospital located in Fortaleza, Ceará, Brazil in 2014. Data collection occurred from January to March 2014, through the analysis of medical records. guided by a data collection instrument. The research project was submitted to the Assis Chateaubriand School Maternity Research Ethics Committee (MEAC), and was approved in the register 513.392 / 2014-14. Results: The sample analyzed was established by high risk pregnant women aged 13 to 40 years. The diagnosis of toxoplasmosis was predominant in the age group between 20 and 30 years. As managers diagnosed with toxoplasmosis reside mainly in the interior of Ceará with statistically significant difference compared to pregnant women residing in the capital. Conclusion: It can be concluded that the analysis analyzed as the variables that were associated with toxoplasmosis were: residing within the state, gestational week between 13 to 27 weeks, normal sharing and using positive IgG serology for toxoplasmosis.