Mode Separation Research Articles

Ultra-high pressure slalom chromatography: Application to the characterization of large DNA and RNA samples relevant in cell and gene therapy

Slalom chromatography (SC), initially co-discovered by Boyes and Kasai in the late 1980s, has recently re-emerged as a breakthrough technique to rapidly analyze DNA samples. With the development of cutting-edge ultra-high pressure liquid chromatography (UHPLC) systems and columns, SC now offers enhanced resolution and sensitivity for analyzing large DNA samples. By revisiting the fundamentals of the SC retention mechanism (non-equilibrium separation mode) and considering the physicochemical properties of DNA biopolymers (contour length, extension under shear flow, relaxation time), we provide analytical chemists with a general strategy and framework for selecting the most relevant applications in the expanding field of cell and gene therapy. We then present proof-of-concept data demonstrating the rapid separation (under 2 min) of plasmid digest samples containing linear double-stranded (ds) DNA macromolecules starting from 2 kbp to 25 kbp, as well as the accurate size determination (±6%) of linear dsDNAs. Additionally, we show rapid baseline separation and quantification of extensible linear dsDNAs, along with the more rigid plasmid dsDNA (supercoiled/circular/nicked circular). We also quantify dsRNA impurities present in vitro transcription (IVT) media used for producing new mRNA therapeutics and assess dsRNA structural heterogeneity (conformational isomers). These findings aim to support in a near future application chemists in addressing emerging bioanalytical challenges in cell and gene therapy by offering advanced SC columns and methods.

Precise modulation of the debonding behaviours of ultra-thin wafers by laser-induced hot stamping effect and thermoelastic stress wave for advanced packaging of chips

Abstract Laser debonding technology has been widely used in advanced chip packaging, such as fan-out integration, 2.5D/3D ICs and MEMS devices. Typically, laser debonding of bonded pairs (R/R separation) is typically achieved by completely removing the material from the ablation region within the release material layer at high energy densities. However, this R/R separation method often results in a significant amount of release material and carbonized debris remaining on the surface of the device wafer, severely reducing product yields and cleaning efficiency for ultra-thin device wafers. Here, we propose an interfacial separation strategy based on laser-induced hot stamping effect and thermoelastic stress wave, which enables stress-free separation of wafer bonding pairs at the interface of the release layer and the adhesive layer (R/A separation). By comprehensively analyzing the micro-morphology and material composition of the release material, we elucidate the laser debonding behavior of bonded pairs under different separation modes. Additionally, we have calculated the ablation threshold of the release material in the case of wafer bonding and established the processing window for different separation methods. This work offers a fresh perspective on the development and application of laser debonding technology. The proposed R/A interface separation method is versatile, controllable and highly reliable, and does not leave release materials and carbonized debris on device wafers, demonstrating strong industrial adaptability, which greatly facilitates the application and development of advanced packaging for ultra-thin chips.

Engineering entangled Schrödinger cat states of separated cavity modes in cavity QED

Engineering entangled Schrödinger cat states of separated cavity modes in cavity QED

Mode separability in offset-based MGDM MMF links: a phase-retrieval-based approach

Mode group diversity multiplexing (MGDM)-based multimode fiber (MMF) systems have been known to be promising solutions for high-data-rate links. However, the challenge of cross-talk within these systems remains a critical concern, since coupling across mode groups diminishes data rates. Past work has shown that optimizing launch conditions and effective spatial filtering can minimize cross-talk across mode groups, although the optimization of the launching has been largely using trial-and-error-based approaches. Characterizing cross-talk limits and quantifying mode coupling requires the use of coherent imaging of the fiber, which is prohibitively complex. In this paper, we present, to our knowledge, a novel approach to characterize the received spatial signal at the MMF output, by obtaining both the amplitude and phase, using just imaging intensity measurements. This is enabled by leveraging recent advances in signal processing to recover the phase from intensity measurements using an alternating minimization-based algorithm for low-complexity phase retrieval, and presents an accurate characterization of mode coupling and estimation of cross-talk in MMF MGDM systems. Experimental validation demonstrates the effectiveness of this approach, particularly in offset-launch-based large-core MMF MGDM systems, where optimal launch parameters are identified to minimize cross-talk. Our findings highlight the significance of optimal launching and spatial filtering in maximizing mode separation, thus reducing cross-talk and enhancing overall system performance, as validated through extensive data rate experiments. The novel phase-retrieval-based fiber characterization can be extended and used to efficiently design spatial filtering solutions for MGDM, such as photonic lanterns and mode multiplexers.

Polyaniline‐Doped Textile‐Based Triboelectric Nanogenerator: Self‐Powered Device for Wearable Electronics

ABSTRACTThe emergence of wearable electronics in contemporary lifestyles has spurred the need for smart fabrics capable of harnessing biomechanical energy. In the present study, a flexible polyaniline‐doped textile‐based triboelectric nanogenerator (PT‐TENG) is designed to harvest low‐frequency mechanical vibrations and convert them into electricity. For the device fabrication, five different textile fabrics are doped with conducting PANI, which is utilized as the tribopositive material, PVC thin film as the tribonegative material, and Al foil as electrodes. The PT‐TENG works in vertical‐contact separation mode, devised in arch structure for easy and complete contact between the working layers. Interestingly, the device featuring a PANI‐doped silk fabric generated the highest output voltage of 257.68 V and a current of 5.36 μA, respectively. Additionally, the PT‐TENG exhibits mechanical durability and electrical stability during continuous 7000 cyclic operations. Furthermore, the PT‐TENG showcases practical applications such as charging commercial capacitors, powering green LEDs and smartwatches, and as a self‐powered touch sensor. Thus, the PT‐TENG offers a facile fabrication process and robustness, highlighting its potential for sustainable energy harvesting in wearable electronics.

Cyano-modified molecular cage silica gel stationary phase: Multi-functional chromatographic performance by high-performance liquid chromatography

This study successfully prepared different loading levels of cyano-functionalized RCC3 molecular cage silica gel stationary phase (RCC3-CN@SiO2) through aldehyde-amine condensation reaction and subsequent modification strategies. Fourier transform infrared spectroscopy, thermogravimetric analysis, nitrogen adsorption-desorption, and scanning electron microscopy confirmed the successful synthesis of RCC3-CN@SiO2 chromatographic stationary phase. The research demonstrates that due to hydrophobic/hydrophilic interactions, π-π interactions, hydrogen bonding, and size-selective porous structure, the stationary phase effectively separates moderately polar and weakly polar compounds in reversed-phase liquid chromatography (RPLC) mode, exhibiting hydrophobic selectivity comparable to the commercial DaisoC18-RP columns. Additionally, the tertiary amine and cyanogen groups on the molecular cage surface enhance the interaction with polar compounds, successfully separating nucleosides, sulfonamides, amino acids, and sugars in hydrophilic interaction chromatography (HILIC) mode. Further applications in the separation analysis of acidic drugs, alkaline drugs, cinnamic acid natural products, and chiral compounds demonstrate the multifunctional chromatographic capabilities for diverse compound types. Compared to Unitary Diol commercial columns, the prepared stationary phase showed significant advantages in wide polarity range separation performance. Moreover, through nucleoside compound separation mode switching analysis, RCC3-CN@SiO2 stationary phase further validates its favorable performance in both RPLC and HILIC modes, demonstrating extensive potential applications in the field of analytical chemistry. Importantly, the stationary phase exhibits efficient separation of nucleoside compounds in pure water systems, aligning with the principles of green analysis.

Design of flat hole-clinching for joining polymer and metal sheets

There is a growing need for joining processes capable of joining dissimilar materials, specifically lightweight materials. In this study, flat hole-clinching (FHC) is developed for joining polycarbonate and AZ31 magnesium alloy sheets. A ductile fracture criterion is calibrated using tensile tests and employed in the finite element analysis of the process to investigate the effect of geometric parameters on the joint characteristics and strength. A tool concept is also proposed for the FHC process. Results show that the FHC process enables to successfully connect these sheets without fracture. The flat hole-clinched joint resisted the maximum force of 0.9 kN in the pull-out test, and failed with bottom separation mode.

Alterable Robotic Skin Using Material Gene Expression Modulation

AbstractRobotic skins that integrate artificial tactile sensing elements can substantially complement the perception dimension of social robots, presenting an indispensable part in human‐robot interaction (HRI). However, existing design frameworks compromise between versatility and sustainability due to the restricted range of characteristics available for a single constituent. Here an alterable robotic skin constructed from homogeneous sensing units are proposed, capable of cyclically realtering their inherent characteristics across a wide spectrum. Necessary characteristics to achieve positioning and pressure sensing subunits can be encoded in the feature motifs and extracted through condition‐induced differentiation, showcasing a remarkable resemblance to the gene expression in the living system. By virtue of this, up to 100‐fold differences in feature parameters are achieved, including modulus, surface state, and conductivity, to drive the target attribute coupling. The trans‐temporal reconstruction of materials enables the superb customization of functional building blocks, advancing the flexible separation and combination of different touch modes, including location, pressure, duration, and motion pattern. As a proof of concept, the alterable robotic skin is demonstrated that integrates a position‐sensing layer and a pressure‐sensing layer. It can accurately distinguish and recognize multi‐dimensional touch motions based on less‐channel data, which showcases an efficient haptic interaction application.

Modeling the coupled bubble-arc-droplet evolution in underwater flux-cored arc welding

For the numerical simulation of underwater wet flux-cored arc welding, the most crucial issue is to investigate the intense interactions between the underwater bubble, arc plasma, and molten metal. However, it is a great challenge to couple them into a single numerical model. In this study, a 3D three-phase flow model is originally established, which successfully couples the dynamic bubble, arc, and droplet. A modified Lee model is employed to realize spontaneous phase transition from liquid water to bubble gas. According to the simulation results, the bubble evolution is divided into four main stages, and two bubble separation modes are recognized. It is found that, both the changing pressure field around the bubble and the varying flow direction of surrounding water contribute to the unique bubble evolution patterns. As for the droplet, its violent up-and-down oscillation at the wire tip is mainly caused by the opposite gas drag forces, which are produced by the turbulent gas flow inside the bubbles. The upward gas drag force can even make the neck of the droplet disappear. With different droplet detaching angles, two predominant droplet transfer modes are numerically produced; when the angle reaches 147°, the droplet is pushed away and becomes a spatter. Furthermore, the underwater arc is found to be subjected to compressions from both the radial direction due to bubble necking and the axial direction due to droplet growth. The arc temperature and velocity vary significantly not only during the whole droplet transfer period, but also within each bubble evolution cycle. To verify the reliability of the model, underwater welding experiments and visual sensing are conducted. The simulated results match well with the experimental ones, with an 8% error in the droplet transfer period and only a 1.4% error in the bubble evolution cycle.

On the greenness of separation modes containing compressed fluids

BackgroundIn the past three decades, liquid chromatography (LC) has been recognized as a significant environmental, health, and safety burden due to its heavy reliance on toxic organic solvents. Various chromatographic modes are in vogue today for complex analyses, such as sub/supercritical fluid chromatography (SFC) and enhanced fluidity liquid chromatography (EFLC). These modes are often advertised as "universally green" compared to the traditional allliquid reversed (RPLC) and normal phases (NPLC). Quantitative greenness evaluations must be done to validate or invalidate this assumption and allow separation scientists to make educated choices when deciding on what mode to use. ResultsIn this work, we modify the Analytical Method Greenness Score (AMGS) to include the cycle time of the instrument, and with the help of the first-order optimality condition (by setting the AMGS gradient = 0), we show that SFC and EFLC are not always the greenest option as they are often thought to be. Most of the greenness metrics have ignored the cycle time of instruments, yet this key component changes the entire AMGS response to flow rate. The complex case of separating tobacco alkaloid enantiomers (nicotine, nornicotine, anabasine, and anatabine) was selected as an illustrative example for comparing and contrasting separation modes using the modified greenness metric. These enantiomers have been selected due to their notorious difficulty in separation over the past 30 years. Using this family of molecules, four unique retention patterns were observed covering a wide variety of retention phenomena seen in small molecule enantioseparations. SignificanceThe modified AMGS metric will assist practicing analytical chemists in assessing the environmental impact of their separation methods from a single run in a given chromatographic mode. The proposed methodology identifies the minimum AMGS score corresponding to the greenest separation for routine chemical analysis.

Wide-pore fully porous mixed-mode octyl/pyridyl-bonded silica material with pH-dependent surface charge reversal for high-performance hydrophobic charge-induction chromatography of proteins

In an attempt to overcome silanophilic interactions like observed on popular reversed-phase butyl‑bonded silica stationary phases in protein HPLC, a mixed-mode stationary phase based on wide pore silica (3 µm, 300 Å) was prepared by co-immobilization of octyl and 2-pyridylethyl ligands. The surface modification was performed by a new approach using synthesized functional silatranes of the above ligands and prewetted silica. It allowed to generate a dense polymeric siloxane layer on the silica surface. Butyl-bonded silica and octyl/3-aminopropyl-bonded mixed-mode silica phases were prepared for comparison. The modified silicas were subsequently characterized by elemental analysis regarding ligand densities, by solid-state 29Si and 13C cross polarization/magic angle spinning nuclear magnetic resonance spectroscopy for confirming the surface-bonded structure, and by pH-dependent ζ-potential measurements via electrophoretic light scattering providing net surface charge information at distinct pH values. While the classical butyl‑bonded stationary phase revealed negative ζ-potential over the entire pH range investigated (pH 3.5–9.5) due to residual silanols and the mixed-mode octyl/3-aminopropyl-bonded silica positive ζ-potential over the entire pH range, pH-dependent charge reversal was observed at approximately pH 5.5 for the octyl/pyridyl-bonded stationary phase. Then, a test set of proteins differing in hydrophobicities and isoelectric points was employed to evaluate the retention characteristics of all three synthesized stationary phases over the pH range of 3 to 7.5 by acetonitrile-gradient elution reversed-phase HPLC. Under acidic conditions (pH 3) the mixed-mode phases octyl/pyridyl-silica and octyl/aminopropyl-silica showed reduced retention and improved peak shapes due to repulsive interactions preventing silanophilic interactions, while protein separations by their hydrophobicities were achieved (repulsive charge-assisted protein RPLC). Finally, the prepared novel mixed-mode octyl/pyridyl-bonded stationary phase was evaluated in hydrophobic charge induction chromatography mode for protein separation of the same test set. Instead of an organic modifier gradient, elution was enforced by a pH gradient from almost neutral to acidic pH at constant organic modifier content of 10 %. This chromatographic mode showed orthogonal retention characteristics and reversed elution order compared to above organic gradient RP-HPLC. In addition, significantly less organic solvent was used under these conditions, classifying it as a green protein LC technology.

Выбор рационального инструментария для анализа полифенолов цветков бессмертника песчаного и листьев артишока колючего в комплексе фармакологических исследований

Background: Pathology of the hepatobiliary system includes a heterogeneous group of diseases of the liver and biliary system caused by viral, bacterial and parasitic infections, neoplasms, toxic chemicals, including alcohol, nutritional errors, metabolic disorders and heart failure. One of the basic groups for pharmacological correction of this group of diseases is the use of hepatoprotectors, drugs that have a predominantly selective effect on the liver. The active ingredient of most plant hepatoprotectors are flavonoids and hydroxycinnamic acids. The most popular plants – hepatoprotectors containing these active substances include – artichoke prickly (Cynara scolymus (L.)) and sandy everlasting (Helichrysum arenarium (L.) Moench), a plant with choleretic action, also capable of hepatoprotective activity. The aim of the study: Development and comparative characterisation of methods for the analysis of polyphenolic composition of sandy everlasting flowers and artichoke leaves in complex pharmacological studies using HPLC and capillary electrophoresis methods. Materials and methods: The sum of polyphenolic compounds was subjected to chromatographic separation in gradient elution mode. Capillary electrophoresis was carried out in a variant of micellar electrokinetic chromatography (MEKC). The buffer solution used was a mixture of: borate buffer 20 mM (pH - 9.3) – beta-cyclodextrin 20 mM – ethyl alcohol (10:10:5). Results: The electrophoregrams of the separation of artichoke leaf extract by the MECC method showed the presence of 7 components belonging to oxycinnamic acids and flavonoids. The dominant ones are chlorogenic acid and luteolin7-glucoside. Similar results were obtained by the HPLC method. The electrophoregram of immortelle flower extract shows 9 components, of which the dominant one belongs to isosalipurposide. Chromatographic analysis of sandy everlasting flower extract showed the presence of the same components. Conclusion: The results of the analysis of the polyphenolic complex of artichoke leaves and sandy everlasting flowers by capillary electrophoresis agree with the data obtained by HPLC chromatography. This allows us to conclude that the MECC method allows the identification and quantification of each component in artichoke leaves and HPLC chromatography flowers along with HPLC. Moreover, the performance of the analysis by CE is more economically feasible than HPLC, since it does not require the use of solvents for the mobile phase and the availability of a set of columns.

The emerging application of LC-based metallomics techniques to unravel the bioinorganic chemistry of toxic metal(loid)s

The on-going anthropogenic emission of toxic metal(loid) species into the environment contaminates the food supply and drinking water resources in various parts of the world. Given that inorganic pollutants cannot be degraded, their increased influx into the bloodstream of babies, children and pregnant women is inevitable. Since the ramifications of the ensuing environmental exposure on human health remain poorly defined, fundamentally new insight into their bioinorganic chemistry in organisms is urgently needed. Based on the flow of dietary constituents through organisms, the interaction of toxic metal(loid) species with biomolecules in the bloodstream deserve particular attention as they play an integral role in the mechanisms of their chronic toxicity. Gaining insight into these bioinorganic processes is hampered by the biological complexity of plasma/red blood cells and the low concentrations of the metal(loid) species of interest, but can be overcome by employing LC techniques hyphenated to atomic spectroscopic detectors (i.e. metallomics techniques). This perspective aims to highlight the potential of unconventional hyphenated separation modes to advance our understanding of the bioinorganic chemistry of toxic metal(loid) species in the bloodstream-organ system. Four examples are illustrated. The application of anion-exchange (AEX) and size-exclusion chromatography (SEC) provided new insight into the blood-based bioinorganic mechanisms that direct Cd2+ and MeHg+ to target organs. AEX chromatography also allowed to observe the formation of complexes between Hg2+ and MeHg+ with L-cysteine at pH 7.4, that are implicated in their organ uptake. Lastly, the application of reversed phase (RP) chromatography revealed a possible cytosolic mechanism by which N-acetyl-L-cysteine binds to MeHg+ in the presence of cytosolic glutathione (GSH). New insight into other bioinorganic processes may advance the regulatory framework to better protect public health.

Rod-type handheld hybrid nanogenerator for mechanical energy harvesting and self-powered speed sensing applications

Nanogenerators offer a promising solution for converting mechanical movements into electricity with significant implications for portable electronics. Herein, we propose a novel approach using magnesium (Mg)-doped zinc oxide (ZMO) nanoflakes (NFs) embedded in polydimethylsiloxane (PDMS) composite films, which serve as the negative tribo-layer in a triboelectric/piezoelectric hybrid nanogenerator (HNG) operating in contact-separation mode. The ZMO NFs, with an optimized Mg concentration for a high dielectric constant, are mixed into PDMS, and their concentration is further optimized to achieve the highest electrical output from the HNG. The optimized device generates a voltage, current, and power density of approximately 186 V, 5.23 μA, and 1.56 W/m2, respectively while also exhibiting high stability. The electricity generated by this HNG is successfully utilized to power commercial portable electronics. To further enhance its practicality, six similar HNGs were fabricated and integrated into a 3D printed structure, forming a rod-type handheld HNG (RTH-HNG). The energy-harvesting capability of the RTH-HNG is systematically investigated under applied external forces. Additionally, the speed-sensing ability of the RTH-HNG during hand-shaking motions is assessed, with the system demonstrating an accuracy of up to 94 % when compared to a commercially available infrared sensor. Moreover, the real-time vibrational energy harvesting capability of the RTH-HNG was demonstrated by attaching it to a bicycle. Therefore, the proposed RTH-HNG can function not only as a mechanical energy harvester for powering small portable electronics but also as a self-sufficient speed sensor for various real-time applications.

Damage imaging identification of plate structures based on linear array near-field MUSIC algorithm

ABSTRACT The paper proposes a damage imaging identification method for plate structures based on piezoelectric Lamb waves and the MUSIC algorithm, focusing on enhancing the accuracy of damage identification by using the sensing signal mode separation technique, and on the MUSIC-algorithm-based damage level evaluation. The mode separation of damage scattering signals is realised by using pairwise geometric symmetry to simplify the processing of sensing signals and improving the accuracy of damage imaging. A damage factor constructed by using the maximum eigenvalue of the sensing signal matrix is proposed, and it is combined with imaging technology to realise the precise locating and preliminary evaluation of damage. A combination of finite element simulation and experimental validation is used to verify the effectiveness of the proposed method. The results show that accurate damage localisation imaging can be obtained by using a mode-separated damage scattering signal; the damage level has an approximately linear relationship with the damage factor, which can be used to initially recognise the damage level. Within a certain level of damage, the proposed method has high accuracy and stability, enhancing the effectiveness of the damage identification technology for plate structures based on the MUSIC algorithm.

A modality separation approach for facial sketch synthesis

AbstractThe technology for face‐to‐sketch synthesis transforms optical face images into a sketch‐style format. However, traditional style losses are insufficient to discern the modal differences between optical and sketch domain images, leading to unclear images. At the same time, generated images lack clarity due to traditional approaches' disregard for high‐frequency texture. To address these issues, a modality separation approach for facial sketch synthesis is proposed. First, a modality separation structure is proposed, using a quicksort algorithm to merge features of optical and sketch images as target modality (positive samples), ensuring the generated images' feature distribution matches real sketches. By controlling the Euclidean distance between generated images (anchors) and both target and filtered modality (positive and negative samples), irrelevant information is effectively filtered out. Next, an edge‐promoting module feeds processed blurry sketch images into the discriminator to enhance robustness. Lastly, a detail optimization module uses Laplacian filtering to extract high‐frequency texture from optical face images for local enhancement. Experimental validation on CUHK, AR, and XM2VTS datasets shows that this method outperforms mainstream sketch face synthesis methods in terms of Fréchet inception distance and learned perceptual image patch similarity, producing more realistic and natural images with richer texture details.

LCxSFC Valve Technologies: Guidelines toward a Successful Online Modulation.

Online two-dimensional liquid chromatography can be used under various separation modes but is sometimes limited in terms of orthogonality, especially for the analysis of neutral compounds. The use of SFC in the second dimension offers a wide choice of mobile and stationary phases, suggesting retention properties complementary to those of the first dimension. Initial works on online LCxSFC coupling published in the literature highlighted the first difficulties of solvent compatibility or potential problems with bubbles created by CO2 in loops. The present work highlights the impact of the interface between the LC and SFC dimensions on the performance of the 2D separation. Six different configurations have been evaluated, differing by the addition of a makeup flow in the first dimension, a division, or a separation of flow paths in the second dimension. Their performances with empty loops eliminated the need for complex trapping columns, regardless of the LC mobile phase nature. Injection in partial fill mode was possible without any problems of CO2 bubble formation, solvent miscibility, pressure, or modulation repeatability in each of the studied configurations. Selected configurations even allowed for the use of a mobile phase split upstream of the valve, so that the online LCxSFC configuration could be as flexible as LCxLC instrumentation in terms of the first dimension flow rate or second dimension injected volume. The obtained results allowed for building guidelines presenting the best interfaces to set up depending on the nature of the mobile phases in both dimensions. Two applications on monomers of lignin and industrial polymers confirmed preliminary results on configuration testing and illustrated that online LCxSFC could now be easily implemented. Precision tests on retention time were conclusive and are promising for the future use of this technique in industrial routines.

Magnetic quadrupolar resonance in a symmetric three-layered plasmonic metasurface

Dark plasmon mode with even symmetry presents an effective way for manipulating light-matter interactions due to its attractive properties of small radiative loss and strongly intensified near-field, which opens up space for both fundamental explorations and optoelectronic device developments. In this paper, we demonstrate magnetic quadrupolar resonance in a symmetric plasmonic metasurface under oblique light incidence. In a three-layered metasurface made of a cross-shaped gold array on top of a magnesium fluoride film backed with a copper ground plane, a magnetic quadrupolar resonance is excited at 37.3 THz with a quality factor of 34, which is four times of the regular magnetic dipolar resonance excited in the same structure. By increasing the incident angle, asymmetry perturbation on the magnetic quadrupolar mode becomes more pronounced as evidenced from its decreased quality factor. In addition, due to the structure symmetry of the used metal cross, the metasurface exhibits polarization-selective excitation of two separate magnetic quadrupolar modes at 37.3 THz and 42.3 THz for the electric field along four symmetry axes of the structure. Our demonstrated distinctive magnetic quadrupolar resonance offers an alternative mode design in plasmonic metamaterials with an improved quality factor, which could be beneficial for metamaterial applications in sensing, optical filtering and infrared emission manipulation etc.

Effect of Ramp Geometry on Single Expansion Ramp Nozzle Performance Characteristics

In high-speed flight regimes, the drag plays a significant role in determining the overall performance of the aerospace vehicle. One proposed solution is to integrate a single expansion ramp nozzle (SERN) at the aft of the vehicle to mitigate the drag effects. This work investigates the effects of nozzle geometry on flow and performance characteristics of SERN with a thrust-optimized parabolic and minimum-length nozzle ramp contours, which have not been explored with regard to these aspects. A computational study is carried out on these two ramp contours using compressible Reynolds Averaged Navier–Stokes equations over a range of nozzle pressure ratio (NPR). In the tested range of NPR, the restricted shock separation is found to be the chief mode of flow separation in SERN, along with the change in the size of recirculation zone and separation bubble. At NPR 3, the thrust-optimized parabolic ramp contour shows an increment of thrust coefficient by 29.2% over the minimum-length nozzle; whereas at NPR 3.5, the minimum-length nozzle demonstrates an increment of thrust coefficient by 56.3% over the thrust-optimized parabolic at 0-deg M cowl angle. Further, in the tested range of NPR, the minimum-length nozzle shows an improved lift coefficient at 5 deg cowl angle.

Random Lasing under Dissipative Tunneling Conditions in a Network Quantum Material

A new mechanism of the generation of a random laser based on a random photonic network with dissipative tunneling of photons between microcavities that are placed at the nodes of such network and contain identical two-level quantum systems has been revealed. It has been shown that an additional source of photon losses in tunneling promotes the separation of individual modes of the random laser and the achievement of the lasing threshold even at a vanishingly small population inversion. In this case, the enhancement of laser modes has an interference nature and is due to the energy redistribution between the nodes of the photonic network that correspond to different signs of the frequency detuning of stationary modes of the random laser from the transition frequency of two-level systems. It has been shown that the traditional lasing mechanism, which demonstrates features of the spectrum of single microcavities, i.e., is almost independent of the topological properties of the network and the tunneling parameter, is present in the region of zero detuning.