Floods are one of the most significant devastating natural hazards around the globe. Recent development in remote sensing technology supports faster and low-cost analysis of flood hazards. This study used the Sentinel-1 SAR data for flood mapping and damage assessment. We selected the October 2022 flood event in Thua Thien Hue province, Vietnam. The Change Detection and Thresholding (CDAT) method was adopted to detect the inundation areas. The results showed that The flood event affected to several districts with Quang Dien being the worst hit, followed by Phu Loc and Huong Tra. Phu Vang had the smallest flooded area. The total inundated area was up to 33,384.08ha. The derived flood map was overlaid onto the current land cover map to conduct an initial evaluation of the potential flood damage corresponding to each land use category. The damage to the land cover was estimated that most of the affected areas were in the cropland and accounted for 77.07% of the total inundated area. The results can assist decision-makers in monitoring and assessing flood damage in Central Vietnam