Sensory Phenomena Research Articles

Stolen Identities, Suspended Lives. Embodied Active Imagination in Clinical Work with Victims of State Terrorism.

Each collective trauma holds its own particularities and forms of horror. When the violence is exerted by the government responsible for the care of the population it is termed state terrorism. The traumatic experience and its subsequent negation create a profound dissociation between two narratives: the explicit, which conceals the true facts, and the implicit, which remains unconscious and unbridgeable. In the gap between the two, life becomes suspended. From a Jungian perspective, this can be understood as the interruption of the process of translation and integration (terms that I will explore in some depth) from implicit sensory phenomena to an explicit representational narrative. This profoundly affects the development of the ego-self axis. In turn, it creates a special challenge for analytic technique that calls for new ways of listening to, and meeting the patient in, that non-verbal, unrepresented territory. Drawing upon clinical material, an embodied perspective of Jungian clinical work is offered to show how the inclusion of the body of patient and analyst enables access to the non-represented, though implicitly encoded, traumatic affective memories stored in the somatic unconscious.

XIV—Existence ‘in’ the Mind

Abstract We often speak of an entity existing only in the mind, but what exactly do we mean when we speak this way? In this paper, I look at different accounts of what it is for something to exist in the mind. I argue that none of these accounts do justice to a specific set of cases involving sensory phenomena like after-images, phosphenes and hallucinations. When a subject experiences a green after-image, we may say that the greenness that the subject sees exists only in her mind, but if I am right, we have no good account of what this amounts to. I then offer a diagnosis for why standard accounts fail in the case of sensory experience, and outline a more promising approach.

“My struggles are largely sensory processing:” The sensory world of autistic people

ABSTRACT This article delved into the sensory experiences of autistic adults, drawing on ethnographic fieldwork conducted in British Columbia, Canada. Thematic analysis of qualitative data revealed how unusual perceptual sensitivities impact the emotional well-being of autistic people, complicating their social interactions and relationships and contributing to social isolation. However, autistic individuals adopt diverse sensory and social coping strategies, and constantly adapt their previous sensory and social experiences to particular social and physical environments. This enables them to deal with their sensory challenges while interacting and socializing with others and engaging in social relationships. These ongoing adaptative processes also produce distinctive sociability patterns and perceptions among autistic people, reflecting both the stress associated with social interaction and the intense desire for it. Accordingly, this study highlighted the need for greater awareness of sensory phenomena and of social and physical environments to understand the daily and life experiences of autistics individuals.

Design Method of Museum Cultural and Creative Products Based on Multi sensory Experience

To explore the design method of museum cultural and creative products based on multi sensory experience, improve product level and user experience, and provide new directions for the development of museum cultural and creative design. The method first introduces the cognitive principles and sensory expression methods of sensory experience, and then focuses on the study of three common multi sensory phenomena: multi sensory integration, synesthesia, and sensory compensation. It analyzes their application in the design of cultural and creative products, summarizes the transformation process of user generated multi sensory experience, and establishes a multi sensory experience cultural and creative product design process based on this. Conclusion: Product design with multi sensory experience can bring users a more comprehensive and profound experience, help promote the inheritance and development of museum culture, and improve the serious problem of homogenization in the cultural and creative industry.

Identifying subgroups of urge suppression in Obsessive-Compulsive Disorder using machine learning

Obsessive-compulsive disorder (OCD) is phenomenologically heterogeneous. While predominant models suggest fear and harm prevention drive compulsions, many patients also experience uncomfortable sensory-based urges (“sensory phenomena”) that may be associated with heightened interoceptive sensitivity. Using an urge-to-blink eyeblink suppression paradigm to model sensory-based urges, we previously found that OCD patients as a group had more eyeblink suppression failures and greater activation of sensorimotor-interoceptive regions than controls. However, conventional approaches assuming OCD homogeneity may obscure important within-group variability, impeding precision treatment development. This study investigated the heterogeneity of urge suppression failure in OCD and examined relationships with clinical characteristics and neural activation.Eighty-two patients with OCD and 38 controls underwent an fMRI task presenting 60-s blocks of eyeblink suppression alternating with free-blinking blocks. Latent profile analysis identified OCD subgroups based on number of erroneous blinks during suppression. Subgroups were compared on behavior, clinical characteristics, and brain activation during task.Three patient subgroups were identified. Despite similar overall OCD severity, the subgroup with the most erroneous eyeblinks had the highest sensory phenomena severity, interoceptive sensitivity, and subjective urge intensity. Compared to other subgroups, this subgroup exhibited more neural activity in somatosensory and interoceptive regions during the early phase (first 30 s) of blink suppression and reduced activity in the middle frontal gyrus during the late phase (second 30 s) as the suppression period elapsed.Heterogeneity of urge suppression in OCD was associated with clinical characteristics and brain function. Our results reveal potential treatment targets that could inform personalized medicine.

Rehabilitation for Unilateral Spatial Neglect

Unilateral spatial neglect (USN) is a symptom of unilateral brain damage resulting in failure to report sensory phenomena in the contra-lesional space. It is associated with motor impairment as well as sensory deficits. Recent research suggests that USN, may be caused by a disruption in the interhemispheric balance of the visual attention network. Based on this hypothesis, non-invasive brain stimulation (NIBS), such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), is utilized in the rehabilitation of USN patients. Presently, inhibitory stimulation by continuous theta burst stimulation (cTBS) on contra-lesional parietal cortex are believed to be the most promising method. Conversely, compensation by attentional network of the non-lesioned hemisphere plays an important role in the recovery of USN. Recent imaging studies revealed that functional and structural connectivity of attentional networks within a lesioned hemisphere and between lesioned and non-lesioned hemispheres affects spontaneous recovery and effectiveness of rehabilitation approach such as prism adaptation therapy. These findings are useful in elucidating the pathophysiology of USN and predicting functional outcome. Furthermore, we hope that understanding the pathophysiology will enable the development of new rehabilitation strategies and appropriate treatment selection.

Sensory over-responsivity and orbitofrontal cortex connectivity in obsessive-compulsive disorder

BackgroundSensory over-responsivity (SOR) in obsessive-compulsive disorder (OCD) is associated with illness severity and functional impairment. However, the neural substrates of SOR in OCD have not yet been directly probed. MethodsWe examined resting-state global functional connectivity markers of SOR in 119 adults with OCD utilizing the CONN-fMRI Functional Connectivity Toolbox for SPM (v21a). We quantified SOR with the sensory sensitivity and sensory avoiding subscales of the Adult and Adolescent Sensory Profile (AASP). We also measured: OCD severity, with the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and Obsessive-Compulsive Inventory-Revised (OCI-R); sensory phenomena with the Sensory Phenomena Scale (SPS); general anxiety, with the Beck Anxiety Inventory (BAI); and depressive symptomatology, with Quick Inventory of Depressive Symptoms, Self-Report (QIDS-SR). ResultsThere was a significant positive relationship of SOR with global connectivity in anterior and medial OFC (Brodmann's area 11, k = 154, x = 14, y = 62, z = −18, whole-brain corrected at FWE p < 0.05). LimitationsFuture investigations should explore neural responses to sensory stimulation tasks in OCD and compare findings with those obtained in other conditions also characterized by high SOR, such as autism spectrum disorder. ConclusionsThis study implicates OFC functional connectivity as a neurobiological mechanism of SOR in OCD and suggests that the substrates of SOR in OCD may be dissociable from both that of other symptoms in OCD, and SOR in other disorders. With replication and extension, the finding may be leveraged to develop and refine treatments for OCD and investigate the pathophysiology of SOR in other conditions.

Sensory phenomena in children with Tourette syndrome or autism spectrum disorder.

Tourette syndrome (TS) and autism spectrum disorder (ASD) are two neurodevelopmental disorders with an onset before the age of 18 years. TS patients frequently reported atypical sensory phenomena (SP). Sensory processing abnormalities are also particularly frequent in ASD individuals. Considering the higher rate of atypical sensory behaviours in both neurodevelopmental disorders, in the present study we analysed sensory experiences in patients with ASD and in patients with TS. We enrolled patients with a primary diagnosis of TS or ASD. All participants were assessed for primary diagnosis and associated comorbidities. The presence of sensory behaviours was investigated using the University of Sao Paulo's Sensory Phenomena Scale (USP-SPS). SP were significantly more represented in the ASD-group versus TS-group, except for sound just-right perceptions and energy to released. ASD participants presented higher mean scores in all fields of USP-SPS severity scale respect on TS patients and healthy controls. The USP-SPS total score had significant positive correlations with the CYBOCS and MASC total scores in the TS cohort. In the ASD group, the USP-SPS total score was significantly negative correlated with the total IQ and marginally positive correlated with ADOS total score. SP are a frequently reported characteristic both of ASD and TS. Future studies are needed to better evaluate the differences on their phenomenology in patients with TS and ASD.

Stranger in the Mirror: Exploring Somatic Defamiliarization

This study explores the centrality of the senses for the maintenance or disruption of people’s commonsensical familiarity with the world. Drawing from in-depth interviews with people affected by depersonalization/derealization, which the American Psychiatric Association defines as a dissociative condition in which people perceive the world as dream-like, I conceptualize what I term somatic defamiliarization. I define somatic defamiliarization as a process whereby people experience previously unquestioned sensory phenomena, such as mundane objects or their bodies, as unfamiliar. Building on Berger and Luckmann’s work, I contend that somatic defamiliarization is a perpetual, albeit latent, condition of social life that threatens reality maintenance. I discuss how the concept of somatic defamiliarization can be applied to explore the somatic qualities of experiential ruptures that people may undergo in various circumstances, such as immigration or war.

Skin Reinnervation by Collateral Sprouting Following Spared Nerve Injury in Mice.

Following peripheral nerve injury, denervated tissues can be reinnervated via regeneration of injured neurons or collateral sprouting of neighboring uninjured afferents into denervated territory. While there has been substantial focus on mechanisms underlying regeneration, collateral sprouting has received less attention. Here, we used immunohistochemistry and genetic neuronal labeling to define the subtype specificity of sprouting-mediated reinnervation of plantar hindpaw skin in the mouse spared nerve injury (SNI) model, in which productive regeneration cannot occur. Following initial loss of cutaneous afferents in the tibial nerve territory, we observed progressive centripetal reinnervation by multiple subtypes of neighboring uninjured fibers into denervated glabrous and hairy plantar skin of male mice. In addition to dermal reinnervation, CGRP-expressing peptidergic fibers slowly but continuously repopulated denervated epidermis, Interestingly, GFRα2-expressing nonpeptidergic fibers exhibited a transient burst of epidermal reinnervation, followed by a trend towards regression. Presumptive sympathetic nerve fibers also sprouted into denervated territory, as did a population of myelinated TrkC lineage fibers, though the latter did so inefficiently. Conversely, rapidly adapting Aβ fiber and C fiber low threshold mechanoreceptor (LTMR) subtypes failed to exhibit convincing sprouting up to 8 weeks after nerve injury in males or females. Optogenetics and behavioral assays in male mice further demonstrated the functionality of collaterally sprouted fibers in hairy plantar skin with restoration of punctate mechanosensation without hypersensitivity. Our findings advance understanding of differential collateral sprouting among sensory neuron subpopulations and may guide strategies to promote the progression of sensory recovery or limit maladaptive sensory phenomena after peripheral nerve injury.

Understanding the Micro, Meso, and Macro Worlds of User Experience

Overview: The article presents a framework for holistically understanding a product’s user experience (UX). Informed by the author’s experience as a UX researcher and manager at Google, it is intended to demystify the competencies that UX researchers can bring to organizations to help propel successful innovation. The framework outlines how users simultaneously inhabit three nested scale dimensions of experience with products (Worlds of UX) and demonstrates that engendering user-centered thinking within organizations requires integrating knowledge from each. The Micro World of UX comprises moment-by-moment experiences: direct sensory and motor phenomena, tasks, tools, and decision-making moments users encounter when using a product to accomplish lower-order goals. The Meso World of UX consists of user journeys: sequences of lower-order goals that form pathways toward higher-order goals. The Macro World of UX is the realm of user–product relationships: how users experience successive user journeys and how user segments orient toward products longitudinally.

Temporally Dissociable Mechanisms of Spatial, Feature, and Motor Selection during Working Memory-guided Behavior.

Working memory (WM) is a capacity- and duration-limited system that forms a temporal bridge between fleeting sensory phenomena and possible actions. But how are the contents of WM used to guide behavior? A recent high-profile study reported evidence for simultaneous access to WM content and linked motor plans during WM-guided behavior, challenging serial models where task-relevant WM content is first selected and then mapped on to a task-relevant motor response. However, the task used in that study was not optimized to distinguish the selection of spatial versus nonspatial visual information stored in memory, nor to distinguish whether or how the chronometry of selecting nonspatial visual information stored in memory might differ from the selection of linked motor plans. Here, we revisited the chronometry of spatial, feature, and motor selection during WM-guided behavior using a task optimized to disentangle these processes. Concurrent EEG and eye position recordings revealed clear evidence for temporally dissociable spatial, feature, and motor selection during this task. Thus, our data reveal the existence of multiple WM selection mechanisms that belie conceptualizations of WM-guided behavior based on purely serial or parallel visuomotor processing.

Self-Report Measures of Sensory Phenomena in Body-Focused Repetitive Behaviors: A Comparison to Healthy Controls

Self-Report Measures of Sensory Phenomena in Body-Focused Repetitive Behaviors: A Comparison to Healthy Controls

A regulatory pathway model of neuropsychological disruption in Havana syndrome.

In 2016 diplomatic personnel serving in Havana, Cuba, began reporting audible sensory phenomena paired with onset of complex and persistent neurological symptoms consistent with brain injury. The etiology of these Anomalous Health Incidents (AHI) and subsequent symptoms remains unknown. This report investigates putative exposure-symptom pathology by assembling a network model of published bio-behavioral pathways and assessing how dysregulation of such pathways might explain loss of function in these subjects using data available in the published literature. Given similarities in presentation with mild traumatic brain injury (mTBI), we used the latter as a clinically relevant means of evaluating if the neuropsychological profiles observed in Havana Syndrome Havana Syndrome might be explained at least in part by a dysregulation of neurotransmission, neuro-inflammation, or both. Automated text-mining of >9,000 publications produced a network consisting of 273 documented regulatory interactions linking 29 neuro-chemical markers with 9 neuropsychological constructs from the Brief Mood Survey, PTSD Checklist, and the Frontal Systems Behavior Scale. Analysis of information flow through this network produced a set of regulatory rules reconciling to within a 6% departure known mechanistic pathways with neuropsychological profiles in N = 6 subjects. Predicted expression of neuro-chemical markers that jointly satisfy documented pathways and observed symptom profiles display characteristically elevated IL-1B, IL-10, NGF, and norepinephrine levels in the context of depressed BDNF, GDNF, IGF1, and glutamate expression (FDR < 5%). Elevations in CRH and IL-6 were also predicted unanimously across all subjects. Furthermore, simulations of neurological regulatory dynamics reveal subjects do not appear to be "locked in" persistent illness but rather appear to be engaged in a slow recovery trajectory. This computational analysis of measured neuropsychological symptoms in Havana-based diplomats proposes that these AHI symptoms may be supported in part by disruption of known neuroimmune and neurotransmission regulatory mechanisms also associated with mTBI.

Prevalence and psychopathology features of mental rituals in patients with obsessive-compulsive disorder: A descriptive exploratory study of 1001 patients.

Mental rituals (MR) are compulsions with no overt behavioural or motoric signs. It is presently unclear whether MR found in obsessive-compulsive disorder are associated with a distinctive clinical profile. The main objectives of this paper were to assess the prevalence and psychopathological correlates of mental rituals in a large sample of OCD patients. This exploratory case-control study compared 519 patients with versus 447 without MR in terms of sociodemographics, presence and severity of obsessive-compulsive symptoms, psychiatric comorbidities, sensory phenomena, suicidality, and insight. Current MR were found in 51.8%, while lifetime MR were found in 55.4% of the sample. The multiple logistic regression model determined that the most relevant clinical factors independently associated with current MR in OCD patients were the absence of any sensory phenomena and the presence of lifetime suicide ideation. Due to its relation to OCD clinical aspects, MR are a frequent feature among OCD patients. It also seems to be associated with a range of features that are probably relevant for treatment, especially sensory phenomena and suicidality.

“Dancing with Spirits”—Spirit art and spirit‐guided experiential ethnographic techniques

AbstractSpiritualist mediums are sought out from a variety of cultures for their advanced spirit communication healing techniques. Otherworldly spirits use mediums to create spirit art, which guides an individual to discover their authentic self and work through self‐limiting beliefs. To serve as a bridge for the spirit world, the medium develops an ability to enter an altered state of consciousness and use a multisensory embodied language to communicate with spirits. I describe this language as “dancing with spirits.” To investigate this language, I use my own spirit art as an innovative experiential ethnographic tool that blends auto‐ethnographic perceptions of spirits with sensory and artistic ethnography, and cultural healing techniques. I provide three case studies of how my spirit art provides unique insights into the less explored experiential dimensions of spirit communication. I layer my experimental ethnographic approach with Deleuze and Guattari's “rhizome” to show that spirit communication overcomes limitations of normal linguistic models. The spirit language serves as a rupture for unconscious forces to offer individually tailored healing and insight to a recipient through heightened sensory and physiological phenomena. Art, altered states of consciousness, and anomalous sensory experiences may offer insights to address a pressing global challenge, mental ill‐health.

Identifying languages in a novel dataset: ASMR-whispered speech.

The Autonomous Sensory Meridian Response (ASMR) is a combination of sensory phenomena involving electrostatic-like tingling sensations, which emerge in response to certain stimuli. Despite the overwhelming popularity of ASMR in the social media, no open source databases on ASMR related stimuli are yet available, which makes this phenomenon mostly inaccessible to the research community; thus, almost completely unexplored. In this regard, we present the ASMR Whispered-Speech (ASMR-WS) database. ASWR-WS is a novel database on whispered speech, specifically tailored to promote the development of ASMR-like unvoiced Language Identification (unvoiced-LID) systems. The ASMR-WS database encompasses 38 videos-for a total duration of 10 h and 36 min-and includes seven target languages (Chinese, English, French, Italian, Japanese, Korean, and Spanish). Along with the database, we present baseline results for unvoiced-LID on the ASMR-WS database. Our best results on the seven-class problem, based on segments of 2s length, and on a CNN classifier and MFCC acoustic features, achieved 85.74% of unweighted average recall and 90.83% of accuracy. For future work, we would like to focus more deeply on the duration of speech samples, as we see varied results with the combinations applied herein. To enable further research in this area, the ASMR-WS database, as well as the partitioning considered in the presented baseline, is made accessible to the research community.

Assessing sensory complaints in the outpatient clinic: predicting neurologic disease versus idiopathic sensory phenomena (S49.006)

<h3>Objective:</h3> To determine which features of sensory complaints can predict the presence of neurologic disease in the outpatient setting. <h3>Background:</h3> Sensory symptoms are common chief complaints in the neurology outpatient clinic. Not all cases are due to neurologic disease. Clinicians should risk stratify patients to determine whether additional testing is warranted. We hypothesized that predictors of neurologic disease (ND) rather than idiopathic sensory phenomena (ISP) would include numbness rather than paresthesias, persistent rather than intermittent symptoms, and focal rather than generalized symptoms. <h3>Design/Methods:</h3> Outpatient visits between 2015–2018 were queried for mentions of the keywords “tingling”, “numbness”, and “paresthesia”. Adult patients with at least one year of follow-up were included. Pre-existing neurologic conditions or prior neuroimaging/electrophysiologic studies were exclusionary. We extracted demographic data and the following symptom features: symptom quality (numbness, tingling), timing (intermittent, persistent), location (generalized, focal, bilateral limbs), and exam findings (normal, abnormal). Patients were categorized as having either ISP or ND based on ICD 10 codes. Relationships between presenting features and odds of ND were evaluated by logistic regression, controlling for demographic variables. <h3>Results:</h3> A total of 1819 cases were reviewed, of which 72 cases were included. Fifty-five patients had ND and seventeen had ISP. Categories of ND included: neuromuscular (53%), demyelinating (19%), headache (12%), and other (15%). The presence of focal symptoms, at least one concerning historical feature, or abnormal exam increased the odds of ND (OR 5.27, p=0.012; OR 21.0, p=0.006; OR 14.9, p=0.005; respectively). Symptom quality and timing were not independently associated with ND. When considering all symptom features and exam together, only abnormal exam was associated with ND (OR 32.13, p=0.011). <h3>Conclusions:</h3> This study quantifies the relative importance of historical features and exam findings that physicians typically consider when evaluating sensory complaints. Focal symptoms and abnormal exam most strongly predict presence of ND and should prompt further workup. <b>Disclosure:</b> Dr. Zuroff has received personal compensation in the range of $500-$4,999 for serving as a Speaker with EMD Serono. Miss Alexis has nothing to disclose. Dr. Do has nothing to disclose.

Reading the Sensory Trajectory of Unmoored Existence and the Poetic Encoding of Wounds in Zsuzsa Bánk’s Der Schwimmer (2002)

Abstract Zsuzsa Bánk’s Der Schwimmer (2002) is a meditation on the trials of flight and dislocation. Underpinned by complex memory dynamics, the narrative reconstructs the fate of several ‘unmoored’ figures whose physical or psychological experiences of liminality exacerbate their exile. Drawing on David Howes’s concepts of ‘emplacement’ and ‘displacement’, the primary objective of this essay is to examine the poetic encoding of sensory tropes underlying the core subjects of memory, trauma and migration in the novel. Firstly, rather than reading this novel primarily as a socio-political document, this article highlights the aesthetic qualities of Der Schwimmer while offering deep insights into the subject-specific experiences of belonging and displacement. Secondly, a focus on the literary interweaving of sensory phenomena illuminates a new and under-researched aspect of transnational writing. Ultimately, this article argues that a critical focus on the sensory can open up innovative ways of understanding the aesthetic organization of Der Schwimmer.

Trait absorption is not reliably associated with brain structure or resting-state functional connectivity

Trait ‘absorption’ is a psychological construct with a rich history that was initially born from early work on hypnotic suggestibility. Absorption characterizes an individual's tendency to become effortlessly engrossed in the contents of experience, whether in terms of external sensory phenomena or internal imagery and fantasy, and is reliably associated with a constellation of psychological, cognitive, and behavioral traits. Here, we conducted a comprehensive neuroimaging investigation of associations between trait absorption and the brain. In particular, we assessed multivariate relationships between absorption scores and neuroimaging measures of grey matter density, as well as static and dynamic resting-state functional connectivity. We investigated these relationships using partial least squares in a discovery dataset (n = 201) and then attempted to reproduce results in an independent replication dataset (n = 68). Results revealed a lack of significant associations between absorption and grey matter density across both datasets, and a significant association between absorption and static resting-state functional connectivity in the discovery dataset which was not replicated in the replication dataset. Additional control analyses further indicated the lack of a reliable brain-absorption relationship, whereas we found a replicable association between the closely related trait of ‘openness to experience’ and resting-state functional connectivity. We conclude that absorption is not reliably associated with brain structure or function in the present datasets and discuss factors that may have contributed to this result. This study serves as the first comprehensive and adequately powered investigation of the neural correlates of absorption and motivates future studies to refine the conceptualization of this perplexing trait.