Sense Research Articles

Improving Team Members' Attention During the OR Briefing or Time Out.

Effective coordination among health care professionals is crucial to achieving optimal outcomes. In the OR, even minor errors can have catastrophic consequences. To mitigate the risk of error, health care professionals have adopted a briefing culture like that used in the aviation industry. Briefings are essential to ensure that everyone involved in a procedure knows the plan and potential risks and is prepared to perform their duties safely and effectively. The fundamental human sense involved in briefings is auditory perception; although important, hearing alone does not equate to focused attention. To enhance the efficacy of briefings, engaging the use of a second sense by adding a visual checklist may increase attentiveness and the chances of early error detection and prevention. Using a projection device may enhance all team members' engagement and participation during the briefing or time-out process and can be an effective tool for improving communication and reducing errors.

Midas++: Generating Training Data of mmWave Radars From Videos for Privacy-Preserving Human Sensing With Mobility

Midas++: Generating Training Data of mmWave Radars From Videos for Privacy-Preserving Human Sensing With Mobility

Functional Morphology of Leg Mechanosensory Organs in Early Postembryonic Development in the Stick Insect (Sipyloidea chlorotica)

The subgenual organ complex of stick insects has a unique neuroanatomical organisation with two elaborate chordotonal organs, the subgenual organ and the distal organ. These organs are present in all leg pairs and are already developed in newly hatched stick insects. The present study analyses for the first time the morphology of sensory organs in the subgenual organ complex for a membrane connecting the two sensory organs in newly hatched insects (Sipyloidea chlorotica (Audinet-Serville 1838)). The stick insect legs were analysed following hatching by axonal tracing and light microscopy. The subgenual organ complex in first juvenile instars shows the sensory organs and a thin membrane connecting the sensory organs resembling the morphology of adult animals. Rarely was this membrane not detected, where it is assumed as not developed during embryogenesis. The connection appears to influence the shape of the subgenual organ, with one end extending towards the distal organ as under tension. These findings are discussed for the following functional implications: (1) the physiological responses of the subgenual organ complex to mechanical stimuli after hatching, (2) the influence of the membrane on the displacement of the sensory organs, and (3) the connection between the subgenual organ and distal organ as a possible functional coupling.

An assessment of pharmacist counselling on the patients’ knowledge of ophthalmic medications

Background: Pharmacist counselling helps patients achieve their treatment goals by improving their medication knowledge, including ocular drugs. The visual system transmits 80% of sensory information; hence, eye health is crucial. Routine pharmacist counselling has been carried out to gain ophthalmic medication knowledge for every patient dispensed with a prescription in the outpatient pharmacy Surabaya eye clinic. However, the result of this counselling on patients’ knowledge has not been evaluated. Objective: The aim of this study is to measure the level of patients’ knowledge of ophthalmic medications. Methods: A cross-sectional study was carried out for one month by interviewing patients. A well-structured questionnaire of 15 questions was developed to assess the patient’s knowledge. The level of knowledge was classified as high, moderate, or low. Results: This study involved a total of 80 patients. The study showed that patients with a high, moderate, or low level of knowledge were represented by 33(41.25%), 45(56.25%), and 2(2.5%) patients, respectively. Demographic characteristics (gender and educational level) did not affect patients’ knowledge of ophthalmic medication (p > 0.05). The knowledge of potential side effects of ophthalmic drugs was least understood. Conclusion: There is a need for improvement in the performance of pharmacist counselling since most patients have moderate to low knowledge of ophthalmic medications.

Effects of inter-stimulus and inter-trial intervals on somatosensory gating

Aim of the study Sensory gating is a human higher cognitive function that serves to suppress excessive sensory information and prevent brain overactivity. To elucidate this function, a paired-pulse stimulation paradigm has been used while recording electroencephalography (EEG), and evaluated as an amplitude ratio of responses to a second stimulus (S2) over responses to the first stimulus (S1). The present study investigated the effects of the inter-stimulus interval (ISI) and inter-trial interval (ITI) on somatosensory gating using somatosensory-evoked potentials (SEPs). Methods In Experiment 1, ISI was set at five conditions: 200, 400, 600, 800, and 1000 ms. In Experiment 2, ITI was set at four conditions: 1, 2, 4, and 8 s. Results ISI affected the S2/S1 amplitude ratios of P22 and N27 at C3’ and N30 at Fz, and these S2/S1 amplitude ratios decreased the most under the 200 and 400-ms conditions. ITI affected the S2/S1 amplitude ratios of P22, N27, and N60 at C3', and especially, the somatosensory gating did not work under the 1-s condition. These results suggest that not all SEP components are modulated in the same manner with changing ISI and ITI. The effects of ISI and ITI independently affected the somatosensory gating. Conclusions Based on our findings, preferable parameters are 200-400 ms for ISI and 4 s or longer for ITI to evaluate the functional mechanisms on somatosensory gating in SEPs.

Exploring Humans, Humanity, and Humanization: a Case Study in The Kite Runner by Khaled Hosseini

The principal aim of this case study is to carry out thorough research to uncover the underlying themes about humans, humanity, and humanization within the novel–The Kite Runner— by Khaled Hosseini. This could be achieved through exploring the thoughts, experiences, interactions, and actions of the fundamental characters (Amir, his father, and Hassan respectively) By so doing, the theme of redemption, forgiveness, and guilt. remorse and the struggle for identity — could be uncovered. The significance of this study stems from the fact that: the readers of this article will gain a deep understanding and insights into human nature traits such as forgiveness, redemption, identity, selfishness, and selflessness. The study seeks to provide answers to such questions: How do the major characters depict the sense of humanity and humanization in an unrest social and political situation in Afghanistan? How does the forgiveness theme play a vital role in the humanization of the rich characters such as Assef and Baba? The study adopts the textual analysis method and closes critical reading appreciation techniques through which the complex characteristics of human nature are explored and studied. The findings of the study are represented in the Scrutiny of the rich themes and the deeper insights into human beings’ complex nature. Although this study has covered some essential themes, yet, further research can be conducted in more depth to fill the gap left uncovered.

Interaction Rules Supporting Effective Flocking Behavior.

Several simulation models have demonstrated how flocking behavior emerges from the interaction among individuals that react to the relative orientation of their neighbors based on simple rules. However, the precise nature of these rules and the relationship between the characteristics of the rules and the efficacy of the resulting collective behavior are unknown. In this article, we analyze the effect of the strength with which individuals react to the orientation of neighbors located in different sectors of their visual fields and the benefit that could be obtained by using control rules that are more elaborate than those normally used. Our results demonstrate that considering only neighbors located on the frontal side of the visual field permits an increase in the aggregation level of the swarm. Using more complex rules and/or additional sensory information does not lead to better performance.

Re-patronage on chain stores: mediating and moderating role of customer engagement and experiential value

We contact the outside world through our five sense organs. This is the goal for business creating and maintaining attractive five senses for better servicescape service quality and sales. Perceived service quality is the level of consumers’ cognition of service quality in a specific situation. That is an important basis for consumers to make purchase and re-patronage decisions. With satisfaction, loyalty and commitment from customers, customer engagement can support customer re-patronage. Experiential value is a sublimation of service value, which is form a deep memory or leave a good impression on a service. Re-patronage intention is usually interpreted as the leading factor of re-purchasing power. Chunghwa Telecom Co., Ltd. (CHT) is the largest integrated telecommunications service chain stores in Taiwan. This study aims to investigate the mediating effect of customer engagement and moderating role of experiential value into the research model to investigate the two moderated moderation effects for the CHT chain stores (n = 937). This study first found that mediating effect of customer engagement and moderating role of experiential value on the relationship between perceived service quality and five senses of servicescape can enhance re-patronage on CHT chain stores. Finally, theoretical and practical implications are presented.

Functional role of P2X7 purinergic receptor in cancer and cancer-related pain.

Numerous studies have revealed that the ATP-gated ion channel purinergic 2X7 receptor (P2X7R) plays an important role in tumor progression and the pathogenesis of cancer pain. P2X7R requires activation by extracellular ATP to perform its regulatory role functions. During tumor development or cancer-induced pain, ATP is released from tumor cells or other cells in the tumor microenvironment (such as tumor-associated immune cells), which activates P2X7R, opens ion channels on the cell membrane, affects intracellular molecular metabolism, and regulates the activity of tumor cells. Furthermore, peripheral organs and receptors can be damaged during tumor progression, and P2X7R expression in nerve cells (such as microglia) is significantly upregulated, enhancing sensory afferent information, sensitizing the central nervous system, and inducing or exacerbating pain. These findings reveal that the ATP-P2X7R signaling axis plays a key regulatory role in the pathogenesis of tumors and cancer pain and also has a therapeutic role. Accordingly, in this study, we explored the role of P2X7R in tumors and cancer pain, discussed the pharmacological properties of inhibiting P2X7R activity (such as the use of antagonists) or blocking its expression in the treatment of tumor and cancer pain, and provided an important evidence for the treatment of both in the future.

Apple-and-pin drawings by blind novices show occluded features: region theory

Abstract Sighted children drawing an apple with a pin through it show the hidden parts of the pin. That is, not only is the pin shown running towards the apple and out the other side, it is also shown inside the apple, without a single break, and so the sketch depicts the occluded parts of the pin. Several investigators have offered theories of the observation. We report here on tangible raised-line drawings by young blind people who are novices at drawing. They also include occluded segments of the pin. To explain the drawings we use the John Willats region theory. In this account, enclosed regions represent the volumes of 3D objects. According to region theory, what is in the interior of an object should be shown in the drawing even if it cannot be seen or touched. As a result, since occluded parts of the pin are inside the apple, blind children, like sighted children, include them in their drawings. In region theory, for both the blind and the sighted, long lines on a 2D pictorial surface represent elongated objects in the scene and regions on the surface represent 3D objects and their contents. The basis of region theory may be that sensory information for pins and lines has high-frequency components, and for apples and regions has lower-frequency components.

Machine Learning Approach to Predict Autism Spectrum Disorder

Autism Spectrum Disorder is one of a group of neuro developmental disorders. ASD's are communication , social interactions, range of play and interests, processing and integrating sensory information. In our research we have used the algorithms like Random forest, SVC, ANN, Logistic regression and the Extra trees to predict that which person has the ASD.

Subclinical structural atypicality of retinal thickness and its association with gray matter volume in the visual cortex of maltreated children

Childhood maltreatment is reportedly associated with atypical gray matter structures in the primary visual cortex (V1). This study explores the hypothesis that retinal structures, the sensory organs of vision, are associated with brain atypicality and child maltreatment and examines their interrelation. General ophthalmologic examinations, visual cognitive tasks, retinal imaging, and structural magnetic resonance imaging (MRI) were conducted in children and adolescents aged 9–18 years with maltreatment experiences (CM) and typically developing (TD) children. The retinal nerve fiber layer (RNFL), the most superficial of the ten distinct retinal layers, was found to be significantly thinner in both eyes in CM. While whole-brain analysis using Voxel-based morphometry revealed a significantly larger gray matter volume (GMV) in the thalamus in CM, no significant correlation with RNFL thickness was observed. However, based on region-of-interest analysis, a thinner RNFL was associated with a larger GMV in the right V1. Although it cannot be ruled out that this outcome resulted from maltreatment alone, CM demonstrated subclinical structural atypicality in the retina, which may also correlate with the immaturity of V1 development. Examination of retinal thickness offers a novel clinical approach to capturing characteristics associated with childhood maltreatment.

Evolutionary trends in the elasmobranch neurocranium

The neurocranium (braincase) is one of the defining vertebrate characters. Housing the brain and other key sensory organs, articulating with the jaws and contributing to the shape of the anteriormost portion of the body, the braincase is undoubtedly of great functional importance. Through studying relationships between braincase shape and ecology we can gain an improved understanding of form-function relationships in extant and fossil taxa. Elasmobranchii (sharks and rays) represent an important case study of vertebrate braincase diversity as their neurocranium is simplified and somewhat decoupled from other components of the cranium relative to other vertebrates. Little is known about the associations between ecology and braincase shape in this clade. In this study we report patterns of mosaic cranial evolution in Elasmobranchii that differ significantly from those present in other clades. The degree of evolutionary modularity also differs between Selachii and Batoidea. In both cases innovation in the jaw suspension appears to have driven shifts in patterns of integration and modularity, subsequently facilitating ecological diversification. Our results confirm the importance of water depth and biogeography as drivers of elasmobranch cranial diversity and indicate that skeletal articulation between the neurocranium and jaws represents a major constraint upon the evolution of braincase shape in vertebrates.

Framework for exploring the sensory repertoire of the human gut microbiota.

Bacteria sense changes in their environment and transduce signals to adjust their cellular functions accordingly. For this purpose, bacteria employ various sensors feeding into multiple signal transduction pathways. Signal recognition by bacterial sensors is studied mainly in a few model organisms, but advances in genome sequencing and analysis offer new ways of exploring the sensory repertoire of many understudied organisms. The human gut is a natural target of this line of study: it is a nutrient-rich and dynamic environment and is home to thousands of bacterial species whose activities impact human health. Many gut commensals are also poorly studied compared to model organisms and are mainly known through their genome sequences. To begin exploring the signals human gut commensals sense and respond to, we have designed a framework that enables the identification of sensory domains, prediction of signals that they recognize, and experimental verification of these predictions. We validate this framework's functionality by systematically identifying amino acid sensors in selected bacterial genomes and metagenomes, characterizing their amino acid binding properties, and demonstrating their signal transduction potential.IMPORTANCESignal transduction is a central process governing how bacteria sense and respond to their environment. The human gut is a complex environment with many living organisms and fluctuating streams of nutrients. One gut inhabitant, Escherichia coli, is a model organism for studying signal transduction. However, E. coli is not representative of most gut microbes, and signaling pathways in the thousands of other organisms comprising the human gut microbiota remain poorly understood. This work provides a foundation for how to explore signals recognized by these organisms.

Tedong (Buffalo): Symbol of Nobility, Humanity, and Entertaiment in Funeral Ceremony in The Indigenous Torajan, Indonesia

In the sociocultural life of Toraja people, buffalo are not ordinary animals. If some people in Indonesia make buffalo as farm animals only, then in Toraja, Indonesia, buffalo as a symbol of social status, humanity, and entertaiment. This is in line with the purpose of this research is to reveal the value of the Tedong (Buffalo) in funeral ceremony. This research is a qualitative descriptive study. Data in this study gained in funeral ceremony. Data is collected through observation techniques, records, interviews, and documentation. The results of the research indicated that tedong (buffalo) in the funeral ceremony is as a marker of a person's nobility. The nobility or social status sign is determined by how many buffalo are sacrificed, which is in line with ritual utterance in rambu solo’ that is pronounced by Tominaa. The more tedong (buffalo) the sacrificed, the higher the social status of one. Conversely, the fewer tedong (buffalos) are sacrificed, the lower the social status of one. In addition, tedong (buffalo) also marks the sense of humanity that looks through the activities of Mantaa Duku'. The value of Buffalo as entertainment seemed in the activity of Ma’ pasilaga tedong.

Visuotactile integration in individuals with fibromyalgia

Our brain constantly integrates afferent information, such as visual and tactile information, to perceive the world around us. According to the maximum-likelihood estimation (MLE) model, imprecise information will be weighted less than precise, making the multisensory percept as precise as possible. Individuals with fibromyalgia (FM), a chronic pain syndrome, show alterations in the integration of tactile information. This could lead to a decrease in their weight in a multisensory percept or a general disruption of multisensory integration, making it less beneficial. To assess multisensory integration, 15 participants with FM and 18 pain-free controls performed a temporal-order judgment task in which they received pairs of sequential visual, tactile (unisensory conditions), or visuotactile (multisensory condition) stimulations on the index and the thumb of the non-dominant hand and had to determine which finger was stimulated first. The task enabled us to measure the precision and accuracy of the percept in each condition. Results indicate an increase in precision in the visuotactile condition compared to the unimodal conditions in controls only, although we found no intergroup differences. The observed visuotactile precision was correlated to the precision predicted by the MLE model in both groups, suggesting an optimal integration. Finally, the weights of the sensory information were not different between the groups; however, in the group with FM, higher pain intensity was associated with smaller tactile weight. This study shows no alterations of the visuotactile integration in individuals with FM, though pain may influence tactile weight in these participants.

Jointly looking to the past and the future in visual working memory

Working memory enables us to bridge past sensory information to upcoming future behaviour. Accordingly, by its very nature, working memory is concerned with two components: the past and the future. Yet, in conventional laboratory tasks, these two components are often conflated, such as when sensory information in working memory is encoded and tested at the same location. We developed a task in which we dissociated the past (encoded location) and future (to-be-tested location) attributes of visual contents in working memory. This enabled us to independently track the utilisation of past and future memory attributes through gaze, as observed during mnemonic selection. Our results reveal the joint consideration of past and future locations. This was prevalent even at the single-trial level of individual saccades that were jointly biased to the past and future. This uncovers the rich nature of working memory representations, whereby both past and future memory attributes are retained and can be accessed together when memory contents become relevant for behaviour.

Jointly looking to the past and the future in visual working memory.

Working memory enables us to bridge past sensory information to upcoming future behaviour. Accordingly, by its very nature, working memory is concerned with two components: the past and the future. Yet, in conventional laboratory tasks, these two components are often conflated, such as when sensory information in working memory is encoded and tested at the same location. We developed a task in which we dissociated the past (encoded location) and future (to-be-tested location) attributes of visual contents in working memory. This enabled us to independently track the utilisation of past and future memory attributes through gaze, as observed during mnemonic selection. Our results reveal the joint consideration of past and future locations. This was prevalent even at the single-trial level of individual saccades that were jointly biased to the past and future. This uncovers the rich nature of working memory representations, whereby both past and future memory attributes are retained and can be accessed together when memory contents become relevant for behaviour.

Corpus callosum morphology and relationships to illness phenotypes in individuals with anorexia nervosa

Anorexia nervosa is an often-severe psychiatric illness characterized by significantly low body weight, fear of gaining weight, and distorted body image. Multiple neuroimaging studies have shown abnormalities in cortical morphology, mostly associated with the starvation state. Investigations of white matter, while more limited in number, have suggested global and regional volume reductions, as well as abnormal diffusivity in multiple regions including the corpus callosum. Yet, no study has specifically examined thickness of the corpus callosum, a large white matter tract instrumental in the inter-hemispheric integration of sensory, motor, and cognitive information. We analyzed MRI data from 48 adolescents and adults with anorexia nervosa and 50 healthy controls, all girls/women, to compare corpus callosum thickness and examined relationships with body mass index (BMI), illness duration, and eating disorder symptoms (controlling for BMI). There were no significant group differences in corpus callosum thickness. In the anorexia nervosa group, severity of body shape concerns was significantly, positively correlated with callosal thickness in the rostrum, genu, rostral body, isthmus, and splenium. In addition, there were significant positive correlations between eating disorder-related obsessions and compulsions and thickness of the anterior midbody, rostral body, and splenium. There were no significant associations between callosal thickness and BMI or illness duration. In sum, those with AN with worse concerns about bodily appearance and worse eating disorder-related obsessive thought patterns and compulsive behaviours have regionally thicker corpus callosum, independent of current weight status. These findings provide important neurobiological links to key, specific eating disorder behavioural phenotypes.

A non-canonical visual cortical-entorhinal pathway contributes to spatial navigation

Visual information is important for accurate spatial coding and memory-guided navigation. As a crucial area for spatial cognition, the medial entorhinal cortex (MEC) harbors diverse spatially tuned cells and functions as the major gateway relaying sensory inputs to the hippocampus containing place cells. However, how visual information enters the MEC has not been fully understood. Here, we identify a pathway originating in the secondary visual cortex (V2) and directly targeting MEC layer 5a (L5a). L5a neurons served as a network hub for visual processing in the MEC by routing visual inputs from multiple V2 areas to other local neurons and hippocampal CA1. Interrupting this pathway severely impaired visual stimulus-evoked neural activity in the MEC and performance of mice in navigation tasks. These observations reveal a visual cortical-entorhinal pathway highlighting the role of MEC L5a in sensory information transmission, a function typically attributed to MEC superficial layers before.