Sensory Esotropia Research Articles

Medial Rectus Disinsertion for the Management of Large-Angle Sensory Esotropia.

Background and Objectives: The aim of the report is to report the outcomes of the medial rectus (MR) disinsertion procedure for the management of large-angle esotropia (ET) patients. Materials and Methods: This is a retrospective case series of patients with large-angle ET who underwent an MR disinsertion procedure between March 2012 to April 2022. The procedure happened accidentally during muscle surgery. The demographic and clinical data, including sex, age, visual acuity, pre- and postoperative angle of strabismus, duction limitations, results of intraoperative forced duction tests, and follow-up duration were collected from medical records. Results: Five patients were enrolled in this study. The mean age was 62.2 ± 9.8 years, and the mean follow-up was 24.8 ± 8.7 months. The ET at the primary position of gaze was 92.0 ± 17.9 prism diopters (PD) before MR disinsertion and 38.0 ± 29.5 PD after MR disinsertion only. Abduction deficiency was -4 before after MR disinsertion, which improved to -1 at the last follow-up. Conclusions: The results of MR disinsertion were not as frustrating as anticipated. MR disinsertion may be considered in patients with large-angle sensory ET who refuse surgery on the opposite eye.

Clinical study of esodeviations in children

Esotropia or convergent strabismus is a common type of squint in children. The esodeviation, the refractive error and the amblyopia should be examined and treated early to achieve good cosmetic correction and to improve Visual acuity.A meticulous history of 25 children up to age of 12 years who presented with esodeviations was taken including the age of onset, duration and previous treatment. They were examined for amount and type of deviation by cover test, hirschberg corneal reflex test, Prism bar cover test and evaluated for refractive error under full cycloplegic correction, for Binocular Single Vision, diplopia, suppression and amblyopia by Worth four-dot test and RAF ruler. Ocular movements and fundus findings were recorded.11 male and 14 female children with esodeviations with age of presentation varying from 9 months to 12 years were evaluated for type of esotropia. In our study the most common type seen in 12 cases (48%) is refractive accommodative esotropia with high hypermetropia. Non-refractive accommodative esotropia greater for near with high AC/A ratio in 5 patients (20%), Partially accommodative (mixed) esotropia in 2 cases, acquired non-accommodative esotropia seen in 2 patients. 1 case each is seen in Infantile esotropia, in Sensory esotropia, in child with Duane’s retraction syndrome (DRS) and in child having cerebral visual impairment (CVI).Our study aimed to diagnose and manage the various types of esodeviations at an early age so as to maintain binocular alignment and a good Visual acuity to avoid progression to amblyopia.

A study of clinical, etiological demographic profile of patients with concomitant esotropia between ages 0-10 years

A study of clinical, etiological demographic profile of patients with concomitant esotropia between ages 0-10 years in a tertiary care hospital to assess various clinical patterns and refractive errors.It is a prospective observation study of patients with concomitant esotropia conducted at Sarojini Devi Eye Hospital, Hyderabad from September 2016 to March 2018. The study included 100 patients who attended the squint department, with chief complaints of inward deviation of eyes. A total of 100 patients were examined, 37 (37%) were of the 0-5 age group, and 63 (63%) were of the 6-10 age group. 41(41%) were male 59 (59%) were of female. 50 (50%) were from urban areas and 50 (50%) rural areas.The majority of the cases were of infantile esotropia 39 (39%) followed by Basic esotropia 34 (34%) sensory esotropia 12 (12%), accommodative esotropia 6 (6%), partially accommodative esotropia 5 (5%) and esotropia in myopia 4 (4%).Amblyopia was seen in 69 (69%) of cases which majority improved with amblyopia therapy. The most common refractive error was hypermetropia 76 (76%) and Myopia was seen in 24 (24%) of cases. AHP in 5.12% of cases, DVD in 15.38%, of cases, IOOA in (64.10%), DVD and IOOA in 10.25% of cases, manifest nystagmus in 10.25% of cases, manifest latent nystagmus in 5.12% of cases were seen.This study provides data on the most prevalent forms and associations of concomitant esotropia. Knowledge of various clinical types and timely intervention will help in the development of binocular single vision.

Persistent diplopia postcataract surgery due to development of sensory esotropia in a case of longstanding senile cataract – A case report

As the number of cataract surgeries worldwide is increasing, the number of cases presenting with diplopia following cataract surgery is also increasing. In most cases, diplopia is temporary and resolves in the first 3 months postcataract surgery; however, in some cases, it becomes persistent causing distress to the patient. In this case report, a 60-year-old female patient presented with persistent diplopia 6 months postcataract surgery, and after proper assessment, she underwent strabismus surgery to correct her diplopia. A review of literature has been done in this regard to focus on the different reasons for strabismus associated with cataract surgeries, and various points to identify these factors presurgery where possible have been illustrated to prevent diplopia postsurgery.

Spontaneous consecutive sensory esotropia: a case series

We present the first case series of patients with no systemic neurologic disease who experienced a spontaneous conversion from an initial exotropia to a sensory esotropia in the absence of strabismus surgery or chemodenervation. The patients in this series all were exotropic in the first 2years of life, with the strabismic eye having decreased vision due to unilateral ocular pathology. All patients demonstrated spontaneous conversion to esotropia between 4 and 8years of age and thereafter clinically demonstrated a high ratio of accommodative convergence to accommodation. There was no discernible relationship between refractive error and the pattern of spontaneous esotropia. The existence of this rare entity may support delayed surgical correction of strabismus in patients with sensory exotropia.

Evaluation of fenestration technique of the medial recuts muscle with resection of ipsilateral lateral rectus muscle in patients with sensory esotropia

Background There is an ongoing need to move toward sutureless surgery with less surgical manipulations, while maintaining the same results achieved by conventional surgery. Aim The aim was to evaluate the safety and the effectiveness of fenestration technique of the medial recuts muscle with resection of ipsilateral lateral rectus muscle in patients with sensory esotropia. Design A prospective, noncomparative, single-institution interventional study was conducted. Patients and methods This is a prospective study conducted on 16 children with sensory esotropia. Fenestration of the medial rectus muscle is a novel technique of weakening of the medial rectus by excising a rectangular wide central part extending from the insertion to a point back 5–8 mm depending on the angle of the esotropia leaving superior and inferior longitudinal muscle sleeves with no muscle sutures needed. Postoperative angle was reported at 3 months and at final follow-up. Results The procedure reduced the angle of esotropia from mean preoperative angle of 36.6±9 (20–50) to 5.3±5.9 (0–20) PD. Satisfactory horizontal alignment, defined as postoperative alignment within 8 PD of orthotropia at distance, was achieved in 81.25% of the cases at 3 months of follow-up. There were no overcorrections. The procedure was well tolerated by patients. Conclusion Fenestration technique is a safe and effective weakening procedure for medial rectus in cases of sensory esotropia.

The causative diseases, common comorbidities and surgical procedures of 948 cases of horizontal sensory strabismus

Objective: To investigate the common causes, onset age of vision impairment and complications of sensory strabismus, and to explore the effective surgical methods for sensory strabismus and associated complications. Methods: In this retrospective study, there were 948 cases of surgical treatment for sensory strabismus from 2005 to 2015 in Tianjin Eye Hospital, including 822 cases of sensory exotropia and 126 cases of sensory esotropia. Causative disease, onset age of vision impairment, eye movement, horizontal and vertical deviation and surgical methods were evaluated. Statistical methods included independent samples t test, Mann-Whitney U test and chi-squared test. Results: Congenital or traumatic cataract was the most common cause of sensory strabismus. Anisometropia, optic atrophy, corneal opacity and retinal detachment were also primary reasons. The mean onset age of vision impairment was (2.3±4.2) years in the sensory esotropia group and (8.8±9.0) years in the exotropia group, and a positive correlation was found between the two groups (t=-8.00, P<0.01). Sensory strabismus occurred with A- or V-pattern in 100 cases (10.5%), nystagmus in 42 cases (5.1%), DVD in 57 cases (6%) and oblique overaction in 134 cases (14.1%;including 54 cases with A- or V-pattern). No statistically significant difference existed between the relevance ratio of A- or V-pattern, oblique overaction and the type of strabismus (χ(2)=0.13, 0.04; P>0.05), but significance difference existed between the relevance ratio of nystagmus, DVD and the type of strabismus (χ(2)=48.33, 12.04; P<0.01). Conclusions: The leading cause of sensory strabismus was cataract. The onset age of vision impairment was earlier in the sensory esotropia group than the exotropia group. Patients were more likely to suffer from DVD and nystagmus in the sensory esotropia group than the exotropia group. Surgeons should make a comprehensive assessment before surgery to design a rational surgical procedure. (Chin J Ophthalmol, 2018, 54: 283-287).

Esotropia and Exotropia Preferred Practice Pattern®

Esotropia and Exotropia Preferred Practice Pattern®

Surgical Treatment of Adult-Onset Esotropia: Characteristics and Outcomes.

To describe the characteristics of the strabismus, surgical management, and outcomes of patients who underwent surgery for adult-onset esotropia. This was a retrospective case study of patients at an academic tertiary referral center who underwent surgical treatment of esotropia acquired at or after age 18 years. Primary outcome measures were resolution of diplopia in primary position and a deviation of 10 prism diopters or less in primary gaze. Additional clinical parameters were assessed. Of 248 patients with adult-onset esotropia who underwent strabismus surgery, all experienced diplopia preoperatively except those with sensory esotropia. The four most common diagnoses were cranial nerve VI palsy in 36% (90 of 248), thyroid eye disease in 18% (45 of 248), age-related distance esotropia in 15% (38 of 248), and decompensated latent esodeviations in 13% (31 of 248) of patients. A variety of surgical procedures were employed, and adjustable sutures were used in 79% (196 of 248). Approximately 80% (158 of 197) of patients present at the 2-month postoperative follow-up visit were aligned within 10 prism diopters, and 72% (140 of 195) experienced resolution of diplopia. Success rates were significantly higher in patients with adjustable sutures. Reoperation rates were low overall at 15% (37 of 248) and were highest in cranial nerve VI palsies and lowest in age-related distance esotropia. Dose-response calculations showed a non-significantly smaller effect per millimeter of recession and resection in cranial nerve VI palsy and age-related distance esotropia. The causes of adult-onset esotropia are diverse. A variety of surgical approaches are employed and, in conjunction with adjustable sutures, provide a good rate of diplopia resolution and acceptable ocular alignment. [J Pediatr Ophthalmol Strabismus. 2017;54(2):104-111.].

Ergebnisse später Therapie von exzentrischer Fixation bei verschiedenen Amblyopieformen

The objective of this study was to describe the therapeutic prognoses for excentric fixation in relation to the underlying diagnoses. We investigated the clinical development of therapy for permanent occlusion (90%) or standard occlusion (10%) in 32 children up to a maximum age of 7 years with the following: strabismus convergens: n = 12, microstrabismus: n = 10, secondary sensory esotropia: n = 2, anisometropias: n = 6, and congenital partial clouding of the optical axis: n = 2. The mean age of all patients at the time of the first visit to the clinic (EV) was 61 ± 12 (37-86) months, with no significant difference in the sub-groups (n > 2) except for the comparison microstrabismus/anisomyopia (p = 0.05). The mean period of the follow-up examinations, obtained with the aid of a survey of the doctors performing these examinations, was 5 years and 10 months ± 4 years and 6 months (6-253 months). Central fixation was achieved for 20 of 32 (63%) of the patients: for 10 of 12 children with infantile esotropia, 1 of 2 children with secondary sensory esotropia, 3 of 10 children with microesotropia, and 5 of 6 children with anisometropia and 1 (already with standard occlusion) of 2 children with partial clouding of the optical axis. The mean time required to achieve central fixation was 4.5 ± 3.6 (1-11) months. The poorest success rate was found for slightly nasal excentric fixation or fixation on the nasal macular wall, and the best rate for fixation on the temporal macular wall, above the foveola or above the papilla. Achieving central fixation correlated significantly--inversely proportional--to the level of refraction of the amblyopic eye (r = -0.4, p = 0.03), as well as with the difference between the refraction of the amblyopic eye and the dominant eye (r = -0.4, p = 0.02) and with the occurrence of astigmatism in the amblyopic eye (r = -0.4, p = 0.04). The typical age at the time of the first visit to the clinic in this study was around 5 years for most of the excentric fixations investigated. This requires greater intervention of occlusion therapy. In this study, the patients with anisomyopia and infantile esotropia showed the best success rates, and the children with microstrabismus showed the poorest success rates. The fixations close to the papilla, temporal macular wall, and over the foveola were shown to be favourable in relation to the prognosis. With microstrabism, a quasi-burned in nasal excentric fixation with binocularity dominated the unsuccessful attempts. With the primary forms of esotropia, a highly hyperopic amblyopic eye is unfavourable in relation to the prognosis.

Optic Disc Abnormalities – Diagnosis, Evolution and Influence on Visual Acuity

Congenital abnormalities of the optic disc are not so rare. The etiology for the most of them is unknown. Visual acuity of affected eye may be minimally or severely affected, depending on the extent of lesion. All of these conditions can be unilateral or bilateral. Children who have unilateral optic disc abnormalities generally present during the preschool years with sensory esotropia. Visual acuity may be unaffected like in optic disc pit, optic disc drusen, fibre medullares, ect. However, during the evolution they may cause a decrease in visual acuity like serous retinal detachment in optic disc pit, atrophy or subretinal neovascularisation in optic disc drusen. Some of them like fibre medullares needs only a good diagnose and they do not have any evolution. Fluorescein angiography and ultrasonography may be crucial diagnostic procedures to discover some of them, like optic disc drusen. Optic disc abnormalities may be associated with other congenital disorders of the eye and often central nervous system malformations. Secondary they may be associated retinal detachment, retinochisis, macular edema, choroid neovascularisation and lipid exudation. Some of these conditions may be found on routine ophthalmologic exam such as optic disc drusen and fibre medullares and often are diagnostically problem. The aim of our study was to present some of our cases with different optic disc abnormalities such as fibre medullares, optic disc coloboma, hypoplasio disc, optic disc drusen and optic disc pit.

Results of Re-operation on the Deviated Eye in Patients with Sensory Heterotropia

PurposeTo evaluate the result of re-operation on the deviated eye of recurred, consecutive or undercorrected sensory strabismus after surgery.MethodsThe medical records of 11 patients who had received second strabismus operation on the deviated eye due to recurred, consecutive or undercorrected sensory strabismus were studied retrospectively.ResultsAmong the 11 patients, five patients were operated for recurred exotropia after surgery of sensory exotropia (group 1), two for consecutive exotropia after surgery of sensory esotropia (group 2), and four for undercorrected esotropia after surgery of sensory esotropia (group 3). Re-operation was performed 19.2±12.6 years after the first operation and the mean preoperative deviation before re-operation was 30.0±8.66 prism diopters (PD), 32.5±10.6PD, and 32.5±8.66PD, respectively. In all cases, a small amount of recession or resection compared with the usual surgical dosage was applied in re-operation on the deviated eye. The mean follow-up period after re-operation was 12.3±14.2 (1-48 months). Among the 11 patients, postoperative deviations less than 10PD were achieved postoperatively in 8 (72.7%) at 1 month and of the 8 patients with follow-up data beyond 6 months, 5 (62.5%) showed orthotropia within 10PD at 6 months or later.ConclusionsThe surgical result of re-operation on the deviated eye of recurred, consecutive or undercorrected sensory strabismus after the first surgery was satisfactory in spite of the reduced amount of surgical correction compared with the surgical dosage recommended for the non-operated eye.

Medial rectus pulley posterior fixation: A novel technique to augment recession

Medial rectus (MR) pulley posterior fixation, a technique of suturing the pulley to its muscle without scleral sutures, may be as effective as traditional scleral posterior fixation in primary treatment of acquired esotropia (ET) with a high AC/A ratio. This study examines the effectiveness of MR pulley posterior fixation for other variants of ET. We retrospectively analyzed the pre- and postoperative alignment of 16 patients: 9 previously operated patients with excess near ET, 4 patients with sensory ET with excess near ET, and 3 patients with large-angle infantile ET. Surgeries involved extraocular muscle recessions and resections in standard doses combined with MR pulley posterior fixation. All 9 reoperated patients were between 0 and 10 prism diopters of distance ET postoperatively. The excess near ET decreased from an average of 12.1 prism diopters preoperatively (range 6-20) to 1.3 prism diopters postoperatively (range, 0-4). Two of the 4 patients with sensory ET were overcorrected at distance (exotropia of 10 and 15 prism diopters, respectively). The excess near ET of these 4 patients decreased from an average of 13.5 prism diopters preoperatively (range, 10-20) to 2.5 prism diopters postoperatively (range, 0-8). In patients with large-angle infantile ET, the addition of pulley posterior fixation resulted in a greater effect than would be predicted for standard MR recessions, particularly at near. Pooling data for all groups, pulley posterior fixation was associated with a highly significant reduction of excess near esotropia postoperatively (P < 0.00001). MR pulley posterior fixation augments MR recession with relatively greater effect at near. Surgical dosage for unilateral recessions and resections combined with MR pulley posterior fixation should be reduced in patients with poor potential for postoperative fusion.

Sensory strabismus--eso or exo?

The type of horizontal strabismus from loss or impairment of vision is thought to depend on patient age at the time of vision loss. Association between the age at onset of vision loss and development of esotropia vs exotropia will be determined. Patients with a diagnosis of sensory strabismus and visual acuity of 20/40 or poorer were reviewed as well as patients with diagnoses consistent with the development of sensory strabismus. Parameters considered were age at onset of vision loss and type of strabismus. Patients were excluded if the age at onset was not clear. Of 123 patients with sensory strabismus reviewed: 82 (67%) had unilateral vision loss; 41 (33%) had bilateral vision loss; 75 (61%) had congenital vision loss; 50 (67%) developed esotropia; 25 (33%) developed exotropia; 48 (39%) had acquired vision loss; 5 (10%) developed esotropia; and 43 (90%) developed exotropia. A significant difference was noted between age at onset and type of horizontal strabismus (X2= 37.44; P <.0001). Of patients with congenital vision loss, 67% developed sensory esotropia and 33% developed sensory exotropia. Of those with acquired vision loss, 10% developed sensory esotropia and 90% developed sensory exotropia. Patients with congenital vision loss are significantly more likely to develop esotropia, P <.005, and those with acquired vision loss are significantly more likely to develop exotropia, P <.001.

Sensory Strabismus: When Does it Happen and Which Way Do They Turn?

Sensory strabismus may be horizontal, vertical or torsional in nature, or any combination of these but by far the most common form is horizontal. What causes the eyes to become esotropic rather than exotropic with the loss or impairment of vision, and are we able to predict which way they will turn? This review of the literature, followed by a review of patients with sensory strabismus indicates that although the literature may be contradictory, there is a strong tendency for patients with congenital vision loss to develop sensory esotropia and for those with acquired vision loss, as young as 22 months of age, to develop sensory exotropia.

The Prevalence of Dissociated Vertical Deviation in Patients With Sensory Heterotropia

We reviewed 281 consecutive patients with sensory esotropia or exotropia to determine the prevalence of dissociated vertical deviation in patients with sensory strabismus. We reviewed the charts of all patients who received a diagnosis of sensory heterotropia or dissociated vertical deviation and who were examined at the Pediatric Ophthalmology Service at the Texas Children's Hospital between 1973 and 1992. Statistical analyses of the prevalence of dissociated vertical deviation were determined after evaluating the direction of the accompanying horizontal strabismus and examining the temporal relationship of the unilateral vision loss. Dissociated vertical deviation was diagnosed in 35 patients (12.5%). It occurred more frequently in sensory esotropia (22 patients, 18.3%) than exotropia (13 patients, 8.1%) (P = .009). The age at which unilateral visual loss occurred did not influence the development of dissociated vertical deviation. Dissociated vertical deviation in patients with acquired loss of vision does not support the contention that dissociated vertical deviation is a genetically predetermined anomaly of binocular vision.