Sensitivity For High-grade Lesions Research Articles

Cervical Cancer to See the Evaluation of the Effectiveness of Colposcopy in Iraqi Women

Background: One of the leading causes of female death in developing nations is cervical cancer, which accounts for one-fourth of all cases globally. Objective: This paper was focused to assess the outcomes of cervical cancer to see the evaluation of the effectiveness of colposcopy in Iraqi women. Patients and methods: This paper was represented as a cross-sectional study to assess the outcomes of cervical cancer to see the evaluation of the effectiveness of colposcopy in Iraqi women where to include from 25th August 2021 to 16th July 2022 into, 50 patients for ages between 25-50 years. This paper was analysed and examine of clinical features for cervical cancer by the SPSS program. Discussion: The specificity of the Swede score was scoring with seven or above was 87% in the current investigation, while the sensitivity for high-grade lesions was 92%. The threshold was lowered to 5, which boosted the sensitivity reached 72.42% and the specificity to 82%. Using a threshold of 5 for the Swedish score, the accuracy of the value of positive prediction is 75.48%. The accuracy considerably increased to 93.28% if the cutoff for the Swede score was set at 7. The results were similar to those that Bowring et al., as well as Strander et al., had previously reported. Conclusion: This study shows the Swede score was good as screening modalities as performance assessed of patients who have lower abdominal pain and discharge per vaginam as well as dyspareunia, abnormal uterine bleeding which colposcopy conducted into pointing of suspicious cervix with the unhealthy case. In comparison between the Swede score >5 and >7, our study noticed Swede score have a sensitivity of 92%, Specificity of 87%, and Accuracy of 93.28% were more perfect in compare with >5.

Clinical value of human papillomavirus genotyping testing in the diagnosis of cervical intraepithelial neoplasia

To Investigate the value of HPV genotyping in diagnosis of cervical intraepithelial neoplasia (CIN). From July 2012 to February 2013, 200 women from Tianjin Medical University General Hospital and 244 women from Affiliated Hospital of the Chinese People's Armed Forces Logistics College were selected to be HPV genotyping test and thin liqid-based cytology test. Consequently, 132 samples were performed colposcopy test and cervical biopsy. HPV prevalence was 26.4% (117/444) in this study. The infection of one type HPV was more common. The top 5 of HPV types were HPV16, 58, 33, 18, and 52. The top 5 of the risk for CIN II and above followed HPV16, 33, 39, 52 and 18. There was no significant difference between age and HPV positive rate (χ² = 0.948, P > 0.05). Multiple infection and cervical lesions rank correlation analysis (r = 0.132, P > 0.05). For CIN II and above disease, cytology positive rate was 90% (44/49), and HPV positive rate was 96% (47/49)cytology combine HPV positive rate was 98% (48/49, χ² = 0.063, P > 0.05). HPV infection should increasing trends with age. Cytology test and HPV genotyping test had good consistency. The combination of them can improve the sensitivity for high-grade lesions.