Sensitive Medical Data Research Articles

Respiratory disease detection in lung auscultation with convolutional neural networks and CVAE augmentation

The main purpose of this work was to investigate the possibility of detecting respiratory diseases in audio recordings of lung auscultation using modern deep learning tools, as well as to explore the possibility of using data augmentation by generating synthetic spectral representations of audio samples. The ICBHI (International Conference on Biomedical and Health Informatics) dataset was used for training, validation and augmentation. The dataset includes lung auscultations of 126 different subjects, there are a total of 920 sounds, of which 810 have signs of chronic diseases, 75 of non-chronic diseases and 35 with no pathology. The stage of data preprocessing includes discretization to 4kHz frequency, as well as filtering of frequency bands that do not carry information value for the task. In the next step, each sample was transformed into a frequency spectrum and Melspectrograms were generated. To solve the problem of class imbalance, the required number of synthetic spectrograms generated by convolutional variation autoencoders was added. At the stage of building the model, the methods of classical convolutional neural networks were used. The quality of the obtained algorithm was evaluated using a 10-fold cross-validation. Also, to assess the generalization of the proposed method, experiments were performed with the split of audio recordings into training and test sets using patient grouping. Qualitative evaluation of the model was performed using sensitivity, specificity, F1-score and Cohen’s kappa. A score of 98.45% F1-score was achieved for the 5-class classification problem which can contribute to the development of ways to synthesize and augment sensitive medical data. In addition, a cons of existing methods in the generalization of the obtained predictions were revealed, which opens the way for further research in the direction of clinical respiratory diseases detection.

Implementing a Secure Cloud-Based System to Safeguard Sensitive Medical Data for Healthcare

In most developed countries, the medical healthcare system is experiencing rapid development from the stage of clinical information to the stage of information dissemination. In all of these countries, it is undeniable that the Internet of Medical Things (IoMT) technologies have contributed in order to develop information medical healthcare. In reality, the development of smart medical healthcare has been hindered by the protection of medical privacy, according to research and acceptance. This is especially true as telecommunications systems continue to expand and wireless sensor networks (WSN) develop, as well as ways to penetrate those checks that have become increasingly difficult. In the smart healthcare system, protecting users’ information remains an outstanding issue. IoMT features and the protection of privacy and security have led to the development of an extended privacy homomorphism algorithm based on scrambling matrixes, an encryption algorithm enhanced by Modified RSA (mRSA), and a method of encrypted data compression that ensures data confidentiality. For the above purpose, we built a prototype system on a demo temporary domain using both hardware and software. According to the results, the proposed scheme protects E-healthcare from potential threats by providing stakeholders with a secure interface and preventing unauthorized users from accessing the mCloud, thus ensuring privacy. E-healthcare services based on cloud technology are protected by the proposed scheme because it is simple and robust.

Estimating the Effectiveness of some biological agents and Palm biochar in control of Dry bubble disease on the second flush of White mushroom Agaricus bisporus

In a time when technology is present in every aspect of our lives, it is crucial to incorporate advanced solutions to protect sensitive medical data in Social Medical Systems (SMS). This study explores the need to improve security in public healthcare by using advanced technologies to strengthen the weaknesses in the growing field of Social Medical Systems. This study specifically examines the analysis of IoT-23 data using machine learning (ML) and deep learning (DL) methods, as technology and healthcare converge. The research highlights the increasing significance of technology in healthcare, specifically focusing on the revolutionary emergence of Social Medical Systems. As these interlinked networks reshape the provision of public healthcare services, security challenges such as data breaches, cyber threats, and privacy concerns become crucial barriers that require innovative solutions. The study utilizes a wide range of machine learning (ML) and deep learning (DL) techniques to examine IoT-23 data, offering a detailed comprehension of the security environment in Social Medical Systems. The chosen models comprise Support Vector Machines (SVM), Isolation Forest, Random Forest, Convolutional Neural Networks (CNN), and Autoencoder. The results and discussions focus on evaluating metrics such as accuracy, precision, recall, and F1 score. These metrics provide insights into how effective each model is in identifying vulnerabilities.

Orthodontic Materials and Antimicrobial Nanomaterials

In a time when technology is present in every aspect of our lives, it is crucial to incorporate advanced solutions to protect sensitive medical data in Social Medical Systems (SMS). This study explores the need to improve security in public healthcare by using advanced technologies to strengthen the weaknesses in the growing field of Social Medical Systems. This study specifically examines the analysis of IoT-23 data using machine learning (ML) and deep learning (DL) methods, as technology and healthcare converge. The research highlights the increasing significance of technology in healthcare, specifically focusing on the revolutionary emergence of Social Medical Systems. As these interlinked networks reshape the provision of public healthcare services, security challenges such as data breaches, cyber threats, and privacy concerns become crucial barriers that require innovative solutions. The study utilizes a wide range of machine learning (ML) and deep learning (DL) techniques to examine IoT-23 data, offering a detailed comprehension of the security environment in Social Medical Systems. The chosen models comprise Support Vector Machines (SVM), Isolation Forest, Random Forest, Convolutional Neural Networks (CNN), and Autoencoder. The results and discussions focus on evaluating metrics such as accuracy, precision, recall, and F1 score. These metrics provide insights into how effective each model is in identifying vulnerabilities.

Soulbound Tokens: Enabler for Privacy-Aware and Decentralized Authentication Mechanism in Medical Data Storage

Context: The digitalization of the healthcare sector faces significant challenges due to the diverse representation of data and their distribution across various hospitals. Moreover, security is a key concern as healthcare-related data are subject to the legal obligations of GDPR and similar data protection legislations. Standardization efforts like HL7 have been implemented to enhance data interoperability. However, authentication still remains a critical issue, even significant challenges. Aim: This research aims to improve and strengthen the authentication process by introducing a novel architecture for decentralized authentication. Additionally, it proposes a new approach to decentralized data management, which is crucial for handling sensitive medical data efficiently. Methodology: The proposed architecture adopts a user-centric approach, utilizing Self-Sovereign Identity (SSI). It introduced a new non-fungible token (NFT) type called Soulbound token (SBT) in the medical context, which will facilitate user authentication across different hospitals, effectively creating a federation of interconnected institutions. Results: The implementation of the proposed architecture demonstrated a significant reduction in authentication time across multiple hospitals. The use of SBT ensured secure and seamless user authentication, enhancing overall system interoperability and data security. The decentralized approach also mitigated the risks associated with centralized authentication servers. Conclusion: The study successfully presents a novel decentralized authentication architecture for the healthcare domain, leveraging SSI and SBTs. This approach not only accelerates the authentication process but also enhances data security and interoperability among hospitals. Future research should explore the scalability of this architecture and its application in other sectors requiring stringent data security measures.

Secured mutual wireless communication using real and imaginary-valued artificial neuronal synchronization and attack detection

This research presents a cutting-edge security framework that integrates optimal Intrusion Detection System (IDS) and Artificial Neural Networks (ANNs)-based key exchange methods to enhance the reliability of mutual wireless communication in Internet of Medical Things (IoMT) networks. The advent of IoMT technology has brought about a significant transformation in patient care and healthcare operations. It allows for real-time monitoring and diagnosis to be conducted remotely. However, the protection of sensitive medical data has become a crucial issue that has to be addressed to maintain privacy and security. IoMT devices, which have limited processing capabilities, are especially susceptible to cyberattacks, therefore requiring the implementation of new security measures. The proposed methodology offers numerous advantages. By utilizing patient sensor data and analyzing network traffic, the suggested solution surpasses current methods in identifying and preventing network threats with increased precision. This research showcases the better effectiveness of Deep Learning (DL) models in identifying intrusions in IoMT settings, by examining 17 Machine Learning (ML) and 6 DL models. The suggested methodology relies on using a neural sequence of ANNs that consist of both real and imaginary-valued components. This approach enables reciprocal learning and synchronization, which in turn facilitates safe key distribution among IoMT devices. This novel method not only guarantees strong key exchange mechanisms but also enhances the overall security of IoMT networks. This paper presents a complete solution to solve the difficulties of protecting wireless communication in IoMT contexts. This approach performs better than comparable methods in the literature.

An advanced cryptographic scheme for DICOM medical image encryption using a novel spatiotemporal chaotic lattice

Ensuring the privacy and security of medical imaging data is crucial. Most existing methods focus on encrypting images in common formats, neglecting the unique challenges posed by medical formats. In this paper an advanced encryption algorithm based on a multi-dimensional and multi-parametric spatiotemporal coupled chaotic lattice (Double-MsCcL) system is proposed. The Double-MsCcL system enhances the complexity of chaotic sequences, and provides a robust foundation for medical image encryption. The encryption method proposed combines double-layer random DNA diffusion and fractal random permutation. Medical information is embedded in the image pixels, serving as the cryptosystem key. The designed double-layer DNA random diffusion algorithm alters pixel values, while the fractal random permutation algorithm disrupts pixel positions. This proposed approach effectively hides sensitive information, strengthens resistance to plaintext attacks, and address the often-overlooked Uint16 format of DICOM images. Comprehensive performance evaluations have shown that the proposed encryption scheme offers significant advantages in protecting sensitive medical imaging data. Our algorithm exhibits better performance in resisting plaintext analysis, statistical, and differential attacks, demonstrating significant security compared to existing state-of-the-art methods, which can be widely applied in the field of modern medical data protection.

Blockchain‐Enabled Decentralized Healthcare Data Exchange: Leveraging Novel Encryption Scheme, Smart Contracts, and Ring Signatures for Enhanced Data Security and Patient Privacy

ABSTRACTThe healthcare industry has undergone a digital transformation in recent years, with the adoption of electronic health records (EHRs) becoming increasingly prevalent. While this digitization offers various advantages, concerns regarding the security and privacy of sensitive medical data have also intensified. Data breaches and cyber‐attacks targeting healthcare organizations have underscored the need for robust solutions to protect patient data. Blockchain technology has emerged as a promising solution due to its decentralized and immutable nature, which ensures secure and transparent data recording. This paper proposes a novel approach that combines blockchain with advanced encryption scheme and privacy protection technique to establish a secure and privacy protected medical data sharing environment. The proposed system consists of three phases such as initialization phase, data processing phase, and authentication phase. The hybrid Feistal‐Shannon homomorphic encryption algorithm (HFSHE) is proposed to encrypt the medical data to ensure data confidentiality, integrity, and availability. Ring signature is integrated to the system to provide additional anonymity and protect the identities of the participants involved in data transactions. In addition, the smart contract developed performs authentication checks on users, generates a time seal, and verifies the ring signature. Through this enhancement, the system becomes more resilient to both external and internal threats, enhancing overall security as well as privacy. A comprehensive security analysis is conducted to compare the proposed method's performance against existing techniques. The results demonstrate the effectiveness of the proposed approach in safeguarding sensitive medical information within the blockchain ecosystem.

Secure aware software development life cycle on medical datasets by using firefly optimization and machine learning techniques

The abstract highlights the critical need for securing sensitive medical data, emphasizing the challenges in the medical domain due to the confidentiality of patient, disease, doctor, and staff information. The proposed study introduces a novel approach using machine learning, specifically integrating the firefly optimization technique with the random forest algorithm, to classify medical data in a secure manner. The significance lies in addressing the security concerns associated with medical datasets, offering a solution that prioritizes confidentiality throughout the software development life cycle (SDLC). The proposed algorithm achieves an impressive accuracy of 96%, showcasing its efficacy in providing a robust and secure framework for the development of applications involving medical data. This research contributes to advancing the field of medical data security, offering a practical solution for safeguarding sensitive information in healthcare applications.

Shielding sensitive medical imaging data

Shielding sensitive medical imaging data

Advancements in brain tumor identification: Integrating synthetic GANs with federated-CNNs in medical imaging analysis

Brain tumors are a significant health concern worldwide, necessitating accurate and timely diagnosis for effective treatment planning and management. However, conventional methods for brain tumor identification through medical imaging analysis often face challenges related to accuracy, efficiency, and privacy concerns. Current approaches may struggle with limited datasets, privacy regulations hindering data sharing, and the need for specialized expertise in interpreting medical images. Accurately identifying brain tumors is pivotal in diagnosis, treatment planning, and patient prognosis. This research proposes a novel approach for advancing brain tumor identification by integrating Synthetic Generative Adversarial Networks with federated convolutional neural Networks in medical imaging analysis. Federated-CNNs are a type of neural network architecture designed for federated learning scenarios. In federated learning, model training occurs locally on data distributed across multiple devices or institutions without exchanging raw data. Federated CNNs allow collaborative model training across these distributed datasets by aggregating local model updates rather than exchanging raw data. This approach ensures that sensitive data remain localized within each participating institution, thus addressing privacy concerns in medical imaging analysis. Our methodology harnesses the power of GANs to generate synthetic brain MRI images, addressing data scarcity issues commonly encountered in medical imaging datasets. These synthetic images are then utilized in conjunction with Federated-CNNs, enabling cooperative model training between many healthcare institutions while maintaining the anonymity and privacy of data. Moreover, integrating Federated CNNs ensures that sensitive medical imaging data remain localized within participating institutions, addressing data privacy concerns and fostering collaboration among medical professionals. The research advances medical imaging analysis by introducing a novel methodology that leverages existing technologies to improve brain tumor identification accuracy. Specifically, the feature extraction phase using DenseNet121, implemented in MATLAB, achieves an outstanding accuracy of 99.82 % and outperforms Various existing methods, including Inception-V3, ResNet-18, and GoogleNet, demonstrating the efficacy of our approach in capturing discriminative features from medical imaging data. This high accuracy underscores the potential of our methodology to enhance diagnostic accuracy and clinical decision-making in neurology and oncology. The research offers a promising avenue for further exploration and innovation in medical imaging analysis, with significant implications for improving patient outcomes and advancing healthcare practices.

Prevention of Unauthorized Access to Electronic Health Records using Docker

This research focuses on securing electronic health records (EHRs) in cloud environments using Docker. The goal is to prevent unauthorized access and data loss while uploading EHRs to the cloud. By leveraging Docker's containerization capabilities, we propose a security framework that includes encryption, access control, and authentication protocols. Through extensive testing, we demonstrate the effectiveness of our approach in enhancing EHR security. This research provides valuable insights for healthcare organizations and cloud service providers seeking to protect sensitive medical data while leveraging the advantages of cloud computing.

Securing Biomedical Audio Data in IoT Healthcare Systems: An Evaluation of Encryption Methods for Enhanced Privacy

Communication technology have advanced quickly since the COVID-19 epidemic started, providing consumers with additional benefits and conveniences. Concerns over the privacy and confidentiality of this data have grown in importance as initiatives that promote the use of audio and video to enhance interpersonal interactions become more common. In the context of the Internet of Things (IoT), audio communications security is essential in the biomedical domain. Sensitive medical data may be compromised in these connections, which include exchanges between patients and doctors and broadcasts of vital signs. To protect patient privacy and reduce cybersecurity threats, strong security measures such as data encryption must be put in place. Our study attempts to address these issues in this environment. Comparative examination of the Chacha20, Salsa20, and Camellia encryption algorithms enabled us to ascertain that Chacha20 performs exceptionally well when it comes to audio file decryption and encryption speed. The results of our trials attest to this encryption method's astounding effectiveness and efficacy. We have also used the noise reduction technique, which is frequently used in audio security to enhance the quality of recordings and make it easier to identify significant information in audio signals. Then, Fourier transform technique, which is also used to analyze audio files and can be used to identify changes, extract hidden information, and authenticate audio files. By doing this, the audio files security and integrity are strengthened.

Healthcare security in cloud‐based wireless sensor networks: Botnet attack detection via autoencoder‐aided goal‐based artificial intelligent agent

SummaryThis paper presents a new method in the field of healthcare security that specifically targets cloud‐based wireless sensor networks (WSNs). The suggested method integrates a goal‐based artificial intelligent agent (GAIA) with an autoencoder (AE) architecture, yielding an autoencoder‐based agent (AE‐A). The main goal of this integrated system is to improve the efficiency of identifying botnet assaults, with a specific emphasis on the evolving security threats related to cloud computing. Our concept is around creating a meticulously calibrated, goal‐driven AI agent tailored explicitly for healthcare applications. The agent meticulously analyses network data and proficiently integrates autoencoder‐enhanced anomaly detection techniques to uncover intricate patterns indicative of botnet activities. The adaptability of the goal‐based AI agent is improved by ongoing real‐time learning, guaranteeing that its responses are in line with the primary goal of neutralizing threats. The autoencoder serves a vital role in the system by functioning as a tool for extracting features. This approach enables the AI Agent to navigate complex information and derive significant insights efficiently. Cloud computing resources greatly enhance the functionalities of a system, enabling scalability, real‐time analysis, and improved responsiveness. Utilizing goal‐driven AI and autoencoder together proves to be a successful strategy in safeguarding healthcare‐oriented WSNs against botnet attacks. This technique takes a proactive stance in ensuring the security of sensitive medical data. The suggested model is evaluated against various models, including the bidirectional long short‐term memory (BLSTM) method, the hybrid BLSTM with recurrent neural network (BLSTM‐RNN) algorithm, and the Random Forest algorithm. The models are evaluated using metrics such as Matthews correlation coefficient (MCC), prediction rate, accuracy, recall, precision, and F1 score analysis. The investigation demonstrates that the suggested model achieved the most significant values of 93% MCC, 94% prediction rate, 91% accuracy, 98% recall, 98% precision, and 98% F1 score, respectively when compared to the existing models.

Predicting treatment response in multicenter non-small cell lung cancer patients based on federated learning

BackgroundMulticenter non-small cell lung cancer (NSCLC) patient data is information-rich. However, its direct integration becomes exceptionally challenging due to constraints involving different healthcare organizations and regulations. Traditional centralized machine learning methods require centralizing these sensitive medical data for training, posing risks of patient privacy leakage and data security issues. In this context, federated learning (FL) has attracted much attention as a distributed machine learning framework. It effectively addresses this contradiction by preserving data locally, conducting local model training, and aggregating model parameters. This approach enables the utilization of multicenter data with maximum benefit while ensuring privacy safeguards. Based on pre-radiotherapy planning target volume images of NSCLC patients, a multicenter treatment response prediction model is designed by FL for predicting the probability of remission of NSCLC patients. This approach ensures medical data privacy, high prediction accuracy and computing efficiency, offering valuable insights for clinical decision-making.MethodsWe retrospectively collected CT images from 245 NSCLC patients undergoing chemotherapy and radiotherapy (CRT) in four Chinese hospitals. In a simulation environment, we compared the performance of the centralized deep learning (DL) model with that of the FL model using data from two sites. Additionally, due to the unavailability of data from one hospital, we established a real-world FL model using data from three sites. Assessments were conducted using measures such as accuracy, receiver operating characteristic curve, and confusion matrices.ResultsThe model’s prediction performance obtained using FL methods outperforms that of traditional centralized learning methods. In the comparative experiment, the DL model achieves an AUC of 0.718/0.695, while the FL model demonstrates an AUC of 0.725/0.689, with real-world FL model achieving an AUC of 0.698/0.672.ConclusionsWe demonstrate that the performance of a FL predictive model, developed by combining convolutional neural networks (CNNs) with data from multiple medical centers, is comparable to that of a traditional DL model obtained through centralized training. It can efficiently predict CRT treatment response in NSCLC patients while preserving privacy.

The Telehealth chain: a framework for secure and transparent telemedicine transactions on the blockchain.

Blockchain technology provides a secure and decentralized platform for storing and transferring sensitive medical data, which can be utilized to enable remote medical consultations. A theoretical framework for creating a blockchain-based digital system created to facilitate telemedicine system. This paper proposes a theoretical framework based on Hyperledger fabric for creating a blockchain-based digital entity to facilitate telemedicine services. The proposed framework utilizes blockchain technology to provide a secure and reliable platform for medical practitioners to interact remotely with patient transactions. The blockchain will serve as a one-stop digital service to secure patient data, ensure privacy, and facilitate payments. The proposed framework leverages the existing Hyperledger fabric platform to build a secure blockchain-assisted telemedicine platform.

Blockchain-Powered Secure Communication Protocol for the Internet of Medical Things (IoMT)

The Internet of Medical Things (IoMT) through network technology provides smart medical devices, equipment, and software to connect different patients and users with medical information. Integrating Blockchain technology into IoMT-based healthcare IoT solutions increases security and privacy. Blockchain’s decentralized architecture ensures data integrity, confidentiality, and traceability of patient information throughout its entire lifecycle. It solves deficiencies in data storage, transmission, and computation in the IoT ecosystem by using encryption technology and smart contracts. This integration provides real-world benefits such as creating tamper-proof documents and building trust between patients and doctors. The research helps improve the security of healthcare systems and highlights the important role of Blockchain in protecting sensitive medical data in the IoT environment.

Analysis of GDPR Compliance in Utilizing Personal Data for Public Health Purposes in Romania.

The General Data Protection Regulation (GDPR), which became effective on May 25, 2016, underscored the significance of confidentiality across various economic and social domains. Within the medical sector, confidentiality of patient health information is meticulously governed by laws, e.g., no. 95/2006 and no. 46/2003. While these laws address numerous privacy aspects within the doctor-patient relationship, it becomes necessary to update them to align with the latest advancements in emerging technologies, particularly in the context of telemedicine. Upon reviewing the overview of rules pertaining to health data processing in Romania, as published by the European Data Protection Board (EDPB) in 2021, and comparing it with the current public health and research laws in Romania, it becomes apparent that there is a regulatory gap concerning the secondary use of health data. This gap is particularly notable in terms of planning, managing and enhancing the healthcare system, as well as utilizing such data for scientific and historical research purposes, leading to the necessity of developing and regulating the European Health Data Space. Although steps have been taken to align the GDPR legislation in Romania, there is still a disproportionality in the regulation of privacy and cyber security with the implementation of new technologies that will collect, process and store sensitive medical data.

Enhancing the Internet of Medical Things (IoMT) Security with Meta-Learning: A Performance-Driven Approach for Ensemble Intrusion Detection Systems.

This paper investigates the application of ensemble learning techniques, specifically meta-learning, in intrusion detection systems (IDS) for the Internet of Medical Things (IoMT). It underscores the existing challenges posed by the heterogeneous and dynamic nature of IoMT environments, which necessitate adaptive, robust security solutions. By harnessing meta-learning alongside various ensemble strategies such as stacking and bagging, the paper aims to refine IDS mechanisms to effectively counter evolving cyber threats. The study proposes a performance-driven weighted meta-learning technique for dynamic assignment of voting weights to classifiers based on accuracy, loss, and confidence levels. This approach significantly enhances the intrusion detection capabilities for the IoMT by dynamically optimizing ensemble IDS models. Extensive experiments demonstrate the proposed model's superior performance in terms of accuracy, detection rate, F1 score, and false positive rate compared to existing models, particularly when analyzing various sizes of input features. The findings highlight the potential of integrating meta-learning in ensemble-based IDS to enhance the security and integrity of IoMT networks, suggesting avenues for future research to further advance IDS performance in protecting sensitive medical data and IoT infrastructures.

Blockchain with optimal deep learning assisted secure data sharing and classification on future healthcare systems

In the future of healthcare, Blockchain (BC) technology holds immense potential for improving the security and privacy of data. By allowing the secure and immutable storage of medical files and healthcare-related transactions, BC ensured that sensitive medical data remains tamper-proof and open only to authorized parties. Patients have greater control over their data's development, revoking or granting access as required, but healthcare workers can streamline data sharing and ensure the integrity of important data. The decentralized nature of BC networks decreases the risk of centralized data breaches, eventually fostering trust and transparency in the healthcare ecosystems. Conversely, deep learning (DL) has great to revolutionize healthcare diagnostics in the future, offering quick and extremely accurate estimates of medical conditions. This technology has greatly enhanced patient solutions, decreased medical expenses, and improved the burden on medical staff by providing appreciated insights into an extensive range of conditions, from cancer to neurological disorders. With this stimulus, this study presents a novel BC with optimal DL-based secure data sharing and classification (BCODL-SDSC) technique in the future healthcare system. The goal of the BCODL-SDSC technique is to secure and thoroughly examine healthcare data using BC and DL techniques. Primarily, the BCODL-SDSC technique enables BC technology to store and maintain the patient’s data from the procedure of several transactions and enable access control to the various stakeholders. For the security of the medical images, the BCODL-SDSC technique applies the Fractional Order Lorenz system (FOLS) based encryption technique with tuna swarm optimization (TSO) algorithm based optimal key generation process. Finally, a multi-stage process performs the classification of the medical images: MobileNetv1 feature extractor, artificial rabbit’s optimization (ARO) based hyperparameter tuning, and stacked recurrent neural network (SRNN) based classification. The experimental outcome of the BCODL-SDSC technique was examined on a benchmark medical image database. An extensive comparative study reported that the BCODL-SDSC technique reaches an effective performance with other models with a maximum accuracy of 99.11%.