Semi-liquid Food Research Articles

Efficacy of Wuda Granule on Recovery of Gastrointestinal Function after Laparoscopic Bowel Resection: A Randomized Double-Blind Controlled Trial.

To evaluate the efficacy and safety of Wuda Granule (WDG) on recovery of gastrointestinal function after laparoscopic bowel resection in the setting of enhanced recovery after surgery (ERAS)-based perioperative care. A total of 108 patients aged 18 years or older undergoing laparoscopic bowel resection with a surgical duration of 2 to 4.5 h were randomly assigned (1:1) to receive either WDG or placebo (10 g/bag) twice a day from postoperative days 1-3, combining with ERAS-based perioperative care. The primary outcome was time to first defecation. Secondary outcomes were time to first flatus, time to first tolerance of liquid or semi-liquid food, gastrointestinal-related symptoms and length of stay. Subgroup analysis of the primary outcome according to sex, age, tumor site, surgical time, histories of underlying disease or history of abdominal surgery was undertaken. Adverse events were observed and recorded. A total of 107 patients [53 in the WDG group and 54 in the placebo group; 61.7 ± 12.1 years; 50 males (46.7%)] were included in the intention-to-treat analysis. The patients in the WDG group had a significantly shorter time to first defecation and flatus [between-group difference -11.01 h (95% CI -20.75 to -1.28 h), P=0.012 for defecation; -5.41 h (-11.10 to 0.27 h), P=0.040 for flatus] than the placebo group. Moreover, the extent of improvement in postoperative gastrointestinal-related symptoms in the WDG group was significantly better than that in the placebo group (P<0.05). Subgroup analyses revealed that the benefits of WDG were significantly superior in patients who were male, or under 60 years old, or surgical time less than 3 h, or having no history of basic disease or no history of abdominal surgery. There were no serious adverse events. The addition of WDG to an ERAS postoperative care may be a viable strategy to enhance gastrointestinal function recovery after laparoscopic bowel resection surgery. (Registry No. ChiCTR2100046242).

Morphology and Cyto-Architecture of the Testis and Assessment of Selected Biochemical Parameters Associated with Male Fertility Following the Consumption of Tom Brown Weaning Diet in Albino Wistar Rats

Objectives/Background Natural products are preferred over synthetic drug as fertility enhancers as they are cost effective. Infertility among men of reproductive age keeps rising. Synthetic drugs ameliorate the problem but leave adverse side effects as men advance in age, hence the need for alternative medicine. Tom brown weaning diet is a processed cereal-based powdery blend which is cooked into a semi-liquid food for children from 6 months and contains good nutrient levels. This work focused on the effects of Tom brown weaning diet on testes of Wistar rats. Method Fifteen Wistar rats were divided into 3 groups namely: Control group, 50% tom brown group and 100% tom brown group. Control received only rat chow, 50% Tom brown group received tom brown diet and normal rat chows at 12 h cycle per time. This cycle was repeated till the end of the experiment. 50% Tom brown group received only tom brown diet throughout the experimental period. The testes were excised, measured, and processed for morphological and histological analysis. Results Average testicular weight and relative weight in the 50% tom brown, 100% tom brown and control groups were not significant at alpha level of P ˂ .05. This was also supported by the normal histological features seen in sections of the testes of rats in all groups as there were no shrinking and denser spermatogenic cells in the seminiferous tubules. Hormonal analysis showed a non-significant difference in the level of FSH and LH at alpha levels of P˂0.05. However, testosterone level increased significantly in 100% group compared to 50% and the control group at P˂ .05. Also, GC-MS study on the diet revealed 30 compounds in the diet. Conclusion This study revealed that Tom brown diet has no detectable damaging effect(s) on the testes but could improve the cytoarchitecture and enhance fertility.

Dietary habits and nutrition status in esophageal cancer patients after esophageal reconstruction.

Surgery is the cornerstone of the treatment of esophageal cancer (EC). This study is to evaluate the dietary habits and nutrition status in EC patients who underwent esophagectomy followed by esophageal reconstruction. This retrospective study included patients with EC who underwent esophagectomy followed by esophageal reconstruction in the Department of Thoracic Surgery I of Peking University Cancer Hospital between February 2014 and December 2018. The primary outcomes were dietary habits and nutrition status. The secondary outcomes were gastrointestinal symptoms and quality of life (QoL). A total of 346 patients were included. At 30 months after the operation, 90.2% of the patients had recovered to regular dietary habits, 72.8% of patients had a restored frequency of preoperative regular food intake, 2.3% of the patients ate more than six times a day, and 0.6% had semi-liquid food because of bad teeth. The nutrition status remained stable after 6 months postoperatively and recovered slightly 1 year after the surgery. At 30 months after the operation, the most common gastrointestinal symptoms were reflux (38.4%), dysphagia (15.3%), hoarseness (11.8%), abdominal distension (6.6%), diarrhea (2.9%), and nausea and vomiting (2.3%). According to the European Organization for Research and Treatment of Cancer, Quality of Life Questionnaire-OG 25 (EORTC QLQ-OG 25), the factors that affected the life quality of patients during follow-up were anxiety, reflux, and dietary limitations. Most patients with EC who underwent esophageal reconstruction recovered to regular dietary habits and stable nutrition status, while some may still suffer from gastrointestinal symptoms, anxiety, and dietary limitations.

Research of the family Mesembrinellidae (Insecta: Diptera)

Adult Mesembrinellidae feeds on decomposed organic matter; their mouthparts are adapted to collect soft or semi-liquid food, including microorganisms. It is known that this family is attractive for feces, and animal substrates. They are potential bioindicators of environmental quality, with some species already evaluated for such use in certain forest environments, and can help to solve ecological problems and diagnose the causes of environmental changes, being an inexpensive way to indicate the conditions of an environment. Muscomorpha is supported by the presence of posterior spiracles, both immature forms, not the last abdominal segment. This infraorder shelters the so-called Muscoid Diptera, insects that are among the groups of greatest economic and medical-veterinary importance. The objective of this work is to verify the biological characteristics of the family Mesembrinellidae (Insecta: Diptera). In terms of the type of research source, we worked with scientific articles published in national and international journals. This modality of production, in addition to being commonly the most valued in the set of bibliographic production, is the most easily accessed. Access to articles was through virtual libraries such as SCIELO, ResearchGate, Hall, USP, UNB, CAPES, and LILACS.

Fabrication, characterization, and emulsifying properties of complex based on pea protein isolate/pectin for the encapsulation of pterostilbene.

In this study, pectin (PEC) and pea protein isolate(PPI) was successfully used to create complexes as a novel delivery system for pterostilbene (PT). When the mass ratio of PEC to PPI was 0.5, the particle size and ζ-potential of PPI-PEC-PT were 119.41±5.68nm and -23.26±0.61mV, respectively, and the encapsulation efficiency (EE) of PT was 90.92±2.08%. The photochemical stability of PT was enhanced after encapsulation. The results of the molecular docking and multispectral analysis demonstrated that the PPI and PT binding was spontaneous and mostly fueled by hydrophobic interactions. The hydrophobicity of PPI was significantly decreased and the emulsification activity and emulsion stability were significantly improved after production with PEC and PT. The best emulsification impact was demonstrated by the PPI-PEC-PT complex. PPI-PEC is an effective PT delivery material, and the PPI-PEC-PT complex is a new functional emulsification material with significant potential in liquid and semi-liquid food and health products.

Taste changes during radiotherapy for head and neck cancer

IntroductionTaste changes (dysgeusia) during radiotherapy for head and neck cancer are associated with malnutrition, tube feeding and reduced toleration of treatment. MethodThe MD Anderson symptom inventory – head and neck (MDASI-HN) questionnaire was completed by patients in a single department receiving radical radiotherapy or chemo-radiotherapy for head and neck cancer during weeks 1 and 4 of radiotherapy. Participants who developed dysgeusia in week 4 completed supplementary questions exploring what foods they could taste and how they managed taste changes. ResultsAt week 4, 97% of 61 participants reported taste changes, 77% reporting moderate or severe changes. 30% of participants reported taste changes during week 1. Patients with oropharyngeal, oral cavity and parotid gland tumours were most likely to develop dysgeusia. Females were more likely than males to report taste changes. A soft, semi-liquid diet was reportedly easier to tolerate as the more food was chewed the worse the taste became. ConclusionsPatients having radiotherapy for all head and neck cancers should be warned of the very high risk of developing taste changes and the time scale for this. Patients with taste changes should be advised a softer diet requiring less chewing will be better tolerated. The finding that females are more at risk than males of dysgeusia needs further investigation. Implications for practicePatients with head and neck cancer should expect taste changes from the start of radiotherapy. Patients with dysgeusia should be advised that soft, semi-liquid foods that require less chewing before swallowing are easier to tolerate and that taste changes day-to-day.

Twelve Years of Establishing the Strategies for Tongue Reconstruction.

Reconstruction after resection of malignant tongue tumors remains one of the most difficult problems in head and neck oncology. Recent trends in tongue reconstruction have focused on optimizing speech and swallowing functions and maximizing quality of life. In the recent literature, several reconstructive strategies including regional flaps and free flaps have been described. A case series of 328 patients underwent oral tongue reconstruction between March 2011 and March 2022. Functional evaluation was performed in all patients 3 months after reconstruction (where the patients required no adjuvant radiotherapy) or after radiotherapy. Total flap necrosis was seen in 5 patients with free flap reconstruction (2 radial forearm flaps, 1 lateral arm flap, and 2 anterolateral thigh flaps), 5 patients with infrahyoid myocutaneous flap, and 1 patient reconstructed with a supraclavicular flap. Our success rate is 96.6%; partial flap necrosis was observed in 11 patients with infrahyoid myocutaneous flap and 2 patients with a supraclavicular flap. Most patients with subtotal glossectomy or smaller defects (type II-IVA defects) could communicate on the phone and had the near-normal capacity for an oral diet. The remaining patients (type IVB-V defects) had significantly lower speech scores. The majority of patients could eat liquid and semiliquid foods. Tongue cancer surgery and subsequent reconstruction posed exciting challenges for the surgeon to optimize tongue function and quality of life for patients. Attention to the principles of tongue reconstruction and choosing appropriate flap for each defect achieve better functional results.

Influence of High-Pressure Homogenization on the Physicochemical Properties and Betalain Pigments of Red Beetroot (Beta vulgaris L.) Juice.

High-pressure homogenization (HPH) is considered an innovative and modern method of processing and preserving liquid and semi-liquid foods. The aim of this research was to examine the impact of HPH processing on the content of betalain pigments and physicochemical properties of beetroot juice. Combinations of the following HPH parameters were tested: the pressure used (50, 100, 140 MPa), the number of cycles (1 and 3) and the applied cooling or no cooling. The physicochemical analysis of the obtained beetroot juices was based on the determination of the extract, acidity, turbidity, viscosity and color values. Use of higher pressures and a greater number of cycles reduces the turbidity (NTU) of the juice. Moreover, in order to maintain the highest possible extract content and a slight color change of the beetroot juice, it was crucial to perform sample cooling after the HPH process. The quantitative and qualitative profiles of betalains have been also determined in the juices. In terms of the content of betacyanins and betaxanthins, the highest values were found in untreated juice at 75.3 mg and 24.8 mg per 100 mL, respectively. The high-pressure homogenization process resulted in a decrease in the content of betacyanins in the range of 8.5-20.2% and of betaxanthins in the range of 6.5-15.0%, depending on the parameters used. Studies have shown that that the number of cycles was irrelevant, but an increase in pressure from 50 MPa to 100 or 140 MPa had a negative effect on pigment content. Additionally, juice cooling significantly limits the degradation of betalains in beetroot juice.

Safety, efficacy, and selection strategy of laparoscopic local gastrectomy for gastrointestinal stromal tumors in the esophagogastric junction.

ObjectiveTo investigate the safety, efficacy, and selection strategy of laparoscopic local gastrectomy for stromal tumors in the esophagogastric junction.MethodsThirty-eight patients with mesenchymal tumors in the esophagogastric junction were retrospectively enrolled from April 2018 to July 2021 in which the upper edge of the tumor is less than 2 cm from the Z-line or has invaded the Z-line <1/2 circumference. Surgical outcomes, complications, recover, and postoperative gastroesophageal reflux of both groups were compared.Results27 patients underwent wedge resection, and 11 underwent resection by opening all of the layers of the stomach wall. Operative time (90.0 vs. 181.8 min, respectively, P = 0.001) was shorter for the WR group vs. RASW. Blood loss (20 vs. 50 ml, respectively, P = 0.012) was less for the WR group vs. RASW. Recovery of the RASW group was slower in terms of time to pass gas (2 vs. 3 days, P = 0.034), time to oral intake (2 vs. 4 days, P = 0.007), time to semi-liquid food intake (4 vs. 8 days, P = 0.003), and postoperative hospitalization (5 vs. 8 days, P = 0.001) vs. WR. In terms of short-term complications (≤30 days), no significant between-group differences were observed. Cardia stenosis did not occur in either group. In the WR group, one patient experienced mild reflux at 6 months and recovered 1 year after surgery. In the RASW group, one patient experienced severe gastroesophageal reflux at 6 months and 1 year after surgery, which was not entirely relieved by taking antacids. No other patients have gastroesophageal reflux.ConclusionLaparoscopic local gastrectomy is safe and feasible for mesenchymal tumors in the esophagogastric junction in which the upper edge of the tumor is less than 2 cm from the Z-line or has invaded the Z-line <1/2 circumference, and has achieved an excellent short-term effect. The choice of surgery is based on the relationship between the tumor and the position of the cardia.

An Introduction to Home Care for Esophageal Cancer

Esophageal cancer is a common tumor of the digestive tract and is a malignant tumor which affect one’s health and is potentially life threatening. The incidence and mortality rate of esophageal cancer in China is relatively high, with the incidence rate being the sixth highest and the mortality rate being the fourth highest among all malignant tumors. The lesion often occurs in the middle segment of the epithelium of the esophagus, often showing a family tendency, and is more likely to occur in middle-aged and elderly men. The typical symptom of esophageal cancer is progressive dysphagia, first with dry food, then with semi-liquid food, and finally with water and saliva. Treatment is divided into surgical treatment, radiotherapy, chemotherapy, and combination therapy. Apart from malnutrition and pain, the treatment can also cause great psychological stress to patients with esophageal cancer. Therefore, diet, pain, and psychological care for patients with esophageal cancer are crucial. Therefore, it more care is given to the patients by medical and nursing staff during hospitalization. However, not much have been discussed about home care for patients with esophageal cancer. In this article, we will talk about the home care of esophageal cancer patients from the following aspects: dietary, pain management, and psychological care.

Effect of an Early Oral Food Intake Strategy on the Quality of Life of Postoperative Patients With Esophageal Cancer.

ObjectiveTo explore the early oral food intake on the quality of life of postoperative patients with esophageal cancer.MethodsA total of 100 patients with esophageal cancer were randomized into an observation group and a control group, with 50 patients in each group. The patients in the control group were routinely indwelt with a gastric tube and fasted for seven days. If no abnormality was found in examinations, the patients were instructed to attempt drinking water and gradually try eating liquid, semi-liquid, and common foods. The patients in the observation group were subjected to the early oral food intake strategy. The recovery and gastrointestinal symptoms of the patients were evaluated using the six-minute walk test and gastrointestinal symptom rating scale (GSRS) at discharge. The quality of life of patients was evaluated using the QLQ-C30 scale and QLQ-OES18 scale during the return visit to the hospital one month after discharge.ResultsThe GSRS score of the observation group was markedly lower than that of the control group. The six-minute walk distance in the observation group was significantly higher than that in the control group; the difference was statistically significant (P < 0.01). In comparing the QLQ-C30 scores of the two groups, the scores in physical function, emotional function, and general health condition in the observation group were higher than those in the control group. In comparing the QLQ-OES18 scores of the two groups, the scores in dysphagia, eating, reflux, pain domains, and choking symptoms in the observation group were lower than those in the control group; the differences were statistically significant (P < 0.01), and there were no statistically significant differences in other symptoms and related functions between the two groups (P > 0.05).ConclusionThe early oral food intake strategy can reduce gastrointestinal symptoms, promote recovery of postoperative patients with esophageal cancer, and improve quality of life.

Medical Nutrition Therapy in Patient With Multiple Fractures, and Liver Injury With Hypoalbuminemia Complications and Moderate Protein Energy Malnutrition: A Case Report

ObjectivesThe mandibular bone is a place of attachment for the muscles of mastication that are actively moving so that it can make it difficult for the patient to carry out the process of chewing food.MethodsA 29 years old male with diagnosis multiple fracture due to a traffic accident. The patient experienced a decrease in oral food worsened 2 days ago because he was difficult to open his mouth due to severe pain when opening his mouth. Looks like a post-surgery wound Mandibular ORIF on the left side of the mandibular region, postoperatively. Exploratory Laparotomy + Liver Repair” in the abdominal. On laboratory examination found the metabolic status Normochromic Normocytic Anemia (11,4), leukocytosis (13,600), thrombocytopenia (143,000), increased NLR (5.42), elevated transaminase enzymes (543/675), Azotemia (1,44), mild hypoalbuminemia (3,0).ResultsMedical nutrition therapy is given gradually according to the patient's eating tolerance, starting from giving 1350 Kcal via oral in the form of semi-liquid food because the patient still has difficulty chewing there until it reaches 2700 Kcal which is assisted by parenteral nutrition. The composition of the macronutrients given. The patient was given oral supplementation in the form of zinc, curcuma, Vitamin A, C, D and snakehead fish extract capsules. The patient was discharged after 12 days of treatment with improved food intake (achieved 100% KET), there was no decrease in anthropometric parameters, the postoperative wound looked dry and improved metabolic status in the form of a decrease in leukocytes towards normal (8.3 × 103/mL), improvement in blood levels platelets (438.000), immune system improvement (1402.9/mL), liver function improvement (43/95), Improvement of kidney function (0.57).ConclusionsOptimal postoperative wound care and adequate medical nutrition therapy with dietary modifications can improve the patient's clinical condition including reducing the inflammatory reaction that occurs and improving the quality of life of patients treated with postoperative repair of mandibular fractures and fractures of the radius/ulna and liver injury due to blunt abdominal trauma.Funding SourcesInstitutions from Department of Nutrition, Faculty of Medicine, Hasanuddin University.

Rheological characteristics of reconstituted freeze‐dried dragon fruit pulp powder: Effect of concentration and temperature

The rheological properties of reconstituted freeze-dried dragon fruit pulp powder (RFD) were studied at different combinations of concentration (25, 35, 45, and 55 °Brix) and temperature (15, 25, 35, and 45°C) using a rheometer. The RFD samples exhibited non-Newtonian fluid behavior. The behavior index ( n ) of the power law was less than one in all the experimental runs, revealing the shear-thinning nature of the RFD sample. The activation energy calculated from the Arrhenius equation at different concentrations was found to be in the range of 5.207 − 19.726 kJ/mol. The effect of concentration on viscosity at different shear rates was found to correlate with the power law type model with higher efficacy than the exponential type model. The combined effect of concentration and temperature was developed using multiple linear regression analyses. The storage modulus (G′) and loss modulus (G″) were estimated for RFD samples for different concentrations at a temperature of 45°C. The experimental data showed that both G′ and G″ increased with the increase of frequency. The RFD sample showed viscoelastic nature, which was revealed by the greater values of G′ than G″ at a specific frequency. This study on rheological behavior would assist with equipment design, consumer acceptability, and engineering calculations during dragon fruit pulp powder processing. Practical applications Dragon fruit is very perishable in nature. The freeze-dried fruit powder can be used as an ingredient in the preparation of food products by reconstituting with water. The addition of water alters the total soluble solids content as well as the intermolecular linkages, affecting the rheological characteristics of the reconstituted sample. Temperature and pressure are two processing factors that might have an impact on the rheological characteristics of a sample. Food rheology explains the flow properties of a liquid or semi-liquid food and contributes to heat and mass transfer during heating, pumping, and mixing. Thus, the rheological study provides information regarding selecting proper unit operation during processing.

Electroacupuncture for postoperative ileus after laparoscopic surgery on colorectal cancer: study protocol for a randomized controlled trial

BackgroundPostoperative ileus (POI) occurs in almost all patients after abdominal laparoscopic surgery, resulting in complications and increasing the length of hospitalization. Electroacupuncture has been used as an alternative therapy for gastrointestinal dysfunction, but its efficacy for POI is inconclusive. The study is designed to determine whether electroacupuncture can accelerate recovery from POI.Methods/designThis study is a three-arm, randomized controlled trial. A total of 105 patients will be randomized into a group receiving electroacupuncture at Tianshu (ST25), a group receiving electroacupuncture at Zusanli (ST36), or a control group in a 1:1:1 ratio. Patients in the electroacupuncture groups will receive electroacupuncture treatment for 4 days from the first day after surgery. The primary outcome consists of the time to first flatus and the time to first defecation. Secondary outcomes include the time to first tolerance of liquid and semiliquid food; the length of the hospital stay; postoperative pain, nausea, and vomiting; abdominal distension; the time to first get out of bed; and postoperative complications. The outcomes will be assessed by the patients themselves every day during hospitalization. Surgeons, nurses, assessors, and statisticians will be blinded to the group assignments. Patients in the two electroacupuncture groups, but not in the control group, will be blinded to the group assignments. The acupuncturists will not be blinded.DiscussionThe aim of this trial is to provide a nonpharmacological therapy for POI and may provide evidence of the effect of electroacupuncture at ST25 or ST36 on POI.Trial registrationChinese Clinical Trial Registry ChiCTR1900027466. Registered on 14 November 2019.

Impact of Foam-Mat Drying on Plant-Based Foods Bioactive Compounds: a Review.

Plant-based foods are recognized by their remarkable content of bioactive compounds. In an attempt to increase plant-based foods shelf-life, technologies like drying can be used. Foam-mat drying is a mild drying technology that removes water, usually by using hot air, from a foam obtained by the whipping of a liquid or semi-liquid food added with a foaming agent. There are several reports on the use of foam-mat drying for extending plant-based foods shelf-life, including reports on the effect of drying on their bioactive compounds. Therefore, this study aimed at reviewing the literature on the impact of foam-mat drying on plant-based foods bioactive compounds published in the last 10 years. Results show that short foam-mat drying time is beneficial to bioactive compounds retention. In addition, hot air temperature between 40-65°C, foam thickness between 0.2 and 1cm and the use of egg white as one of the foaming agents leads to high bioactive retention. Egg white is also the most used foaming agent. Regarding the mathematical models used for fitting the foam-mat drying kinetics, the Page model was shown as the most proper model. Foaming agent concentration is a delicate parameter, as its increase in foam formulation may beneficially enhance drying rates but, at the same time, it dilutes bioactive compounds and may cause their loss by oxidation. In conclusion, foam-mat drying stands out as a suitable technology for producing food powders with high bioactive retention.

An in-depth description of head morphology and mouthparts in larvae of the black soldier fly Hermetia illucens

The larvae of the black soldier fly (BSF) Hermetia illucens are increasingly being used for waste management purposes given their ability to grow on a wide range of organic decaying materials. Although significant efforts have been spent to improve the mass rearing of BSF larvae on specific substrates and their bioconversion capability, little is known about the biology of this insect, especially with regards to the digestive system.In this study, we analyzed the morphology of the head and buccal apparatus of H. illucens larvae by using optical and scanning electron microscopy, evaluating the different mouthparts and their modifications during larval development.Our analysis showed that the larval head of H. illucens presents similarities to those of campodeiform insect larvae, whereas the mandibular-maxillary complex represents a food intake solution typical of Stratiomyidae that enables BSF larvae to ingest semiliquid food. The mouthparts resemble a “tunnel boring machine”, where the hypopharynx separates finer organic particles from coarser and inorganic ones.

The clinical value of totally laparoscopic stomach-partitioning gastrojejunostomy for malignant gastric outlet obstruction

Objective: To explore the clinical value of totally laparoscopic stomach-partitioning gastrojejunostomy (TLSPGJ) for malignant gastric outlet obstruction. Methods: The clinical data of 9 gastric cancer patients who underwent TLSPGJ in Department of Pancreatic and Gastric Surgery, Cancer Hospital between September 2018 and September 2019 were retrospectively analyzed. Results: The mean operative blood loss of 9 cases were (13.3±5.0) ml, and the average operative time was (103.3±10.6) min. All patients received clear flow food on the first day after surgery. Postoperative first exhaust time was (3.1±0.8) days and the average postoperative hospital stay was (5.4±1.1) days. All of the 9 patients could tolerate semi-liquid food at discharge, and no postoperative complications such as bleeding or delayed gastric emptying occurred. Conclusion: TLSPGJ is an effective treatment for gastric output tract obstruction caused by malignant tumor.

Application value of parallel and cross-to-overlap anastomosis method in three-dimensional laparoscopic radical resection of right hemicolon cancer

Objective To investigate the application value of parallel and cross-to-overlap anastomosis method (PCOA) in three-dimensional (3D) laparoscopic radical resection of right hemicolon cancer. Methods The retrospective cross-sectional study was conducted. The clinicopathological data of 138 patients who underwent 3D laparoscopic radical resection of right hemicolon cancer at Henan Provincial People′s Hospital between July 2016 and July 2019 were collected. There were 83 males and 55 females, aged from 30 to 76 years, with a median age of 64 years. All the 138 patients with right hemicolon tumors were diagnosed as malignant tumors by enteroscopy and pathological examination before operation. The lymph node dissection and radical resection of right hemicolon cancer were performed according to the 9th edition of Japanese General Rules for Cancer of Colon, Rectum and Anus of the Japanese Colorectal Cancer Association. Observation indicators: (1) surgical situations; (2) postoperative conditions; (3) follow-up. Follow-up was conducted by outpatient examination or telephone interview to detect survival of patients and tumor recurrence and metastasis up to September 2019. Measurement data with normal distribution were represented as Mean±SD. Measurement data with skewed distribution were represented as M (range). Count data were represented as percentages or absolute numbers. Results (1) Surgical situations: all the 138 patients underwent 3D laparoscopic radical resection of right hemicolon cancer using PCOA to reconstruct digestive tracts, without conversion to open surgery. The operation time, time for PCOA, and volume of intraoperative blood loss was (151.0±54.0)minutes, (20.1±2.0)minutes, and (60±21)mL. (2) Postoperative situations: the time to first flatus, time to semi-liquid food intake, length of auxiliary incision, and incidence rate of postoperative complications were (2.5±0.4)days, (4.0±1.3)days, (3.0±0.2)cm, and 3.62%(5/138), respectively. Of the 5 patients with postoperative complications, 1 patient with intestinal obstruction was cured after conservative treatment including gastrointestinal decompression and nutritional support, 1 patient with anastomotic leakage was cured after conservative treatment including gastrointestinal decompression, local patency drainage, infection control and nutritional support, 1 patient with ascites and abdominal infection was cured after computed tomography-guided percutaneous catheter drainage, 1 patient with incisional infection was cured by controlling infection, strengthening dressing changes, local irrigation and drainage, 1 patient with pulmonary infection was cured after anti-infective treatment.The number of lymph nodes dissected after surgery, duration of postoperative hospital stay, and hospital expenses were 19±8, (7.2±4.1)days, and (4.8±1.4)×104 yuan. All the 138 patients were confirmed as colonic adenocarcinoma by postoperative pathological examination, including 27 cases of poorly differentiated adenocarcinoma, 92 cases of moderately differentiated adenocarcinoma, 10 cases of highly differentiated adenocarcinoma, and 9 cases of mucinous adenocarcinoma. (3) Follow-up: 133 of 138 patients were followed up for 2-38 months, with a median follow-up time of 18 months. During the follow-up, 2 patients died, 1 of which was detected multiple liver metastases at postoperative 16 months and died at postoperative 21 months, and the other was detected multiple liver metastases at postoperative 20 months and died at postoperative 24 months. Eight patients had distant metastasis, including 5 cases of liver metastasis, 1 case of lung metastasis, and 2 cases of abdominal metastasis. The 10 patients with death and tumor metastasis were confirmed as stage Ⅲ by postoperative pathological examination, and the other 123 patients were generally in good condition. Conclusion PCOA is safe and effective for 3D laparoscopic radical resection of right hemicolon cancer. Key words: Colonic neoplasms; Digestive tract reconstruction; Parallel and cross-to-overlap anastomosis; Surgery for right hemicolon cancer; Three-dimensional; Laparoscopy

Suppression mechanism of l-arginine in the heat-induced aggregation of bighead carp (Aristichthys nobilis) myosin: The significance of ionic linkage effects and hydrogen bond effects

The suppression mechanism of l-arginine (Arg) in fish myosin heat-induced aggregation was investigated in this work. The hydrodynamic radius determined by dynamic light scattering (DLS) and the turbidity of a myosin solution decreased in a dose-dependently manner with Arg after heating, especially in a solution without pH modification (P < 0.05). The surface hydrophobicity of myosin exhibited the same trend as that for hydrodynamic radius and turbidity (P < 0.05). The myosin secondary structures clearly changed with Arg concentration during heating (P < 0.05). These results demonstrate that positively-charged Arg could form ionic interactions with negatively charged myosin, as well as promote repulsion between myosin molecules induced by higher pH values. Furthermore, the resultant hydrogen bonding observed indicated that, in addition to Arg having ionic linkage effects, the specific structure of Arg played an important role in the suppression of myosin aggregation. Essentially, Arg markedly disturbed the hydrogen bonds of the myosin backbone and formed new hydrogen bonds with myosin molecules via two amino groups (-NH2), which are part of the guanidinium moiety of Arg, preferentially hydrogen bonding with the backbone carbonyl oxygen atoms of myosin molecules. This work provides support for using Arg as an additive to modify the texture of fish products to produce liquid and semiliquid food suitable for the elderly consumers in an aging society.

Sub-analysis of real nutrition of patients with jaw fractures

To evaluate the home real nutrition of patients with the mandible fractures during the treatment. Was investigate 57 men aged 18–59 years with a fractured mandible in II clinics of ТМА. All patients given appropriate surgery and drug treatment. Material collection was carried out 13–20 days after splinting, through interviews and questionnaires. Results: Intermaxillar fixation blocks chewing process, as they are forced to take liquid and semiliquid food. As a result of the survey it was found that calorific value of rations patients was within minimal 1080 kcal/day, maximal energetic value was 3300 kcal/day(p > 0.01) and an average of 2030 ± 35 kcal / day, had no statistically significant differences (p > 0.05). The energy value of the daily diet of most respondents (77%) was lower than the average daily energy expenditure even of a healthy person. 8%of patients consumed diet greater than 3000 Kcal/day. The diet was poor patients to proteins, especially animals. The protein intake was on average 63,8 ± 1,3 (p > 0.05) was the diet of women, 74,4 ± 1,8 of men. Such a diet is reflects at outcome major diseases. The diet of patients with jaw fractures has insufficient nutritional value, do not correspond on hygiene standards, also low biological inferiority. It is the need to correct the diet of patients to recommend the inclusion in foods rich in complete protein, unsaturated fats, enriched with vitamins, elements. It is necessary to conduct studies of patients to proper nutrition.